• 한국융합학회논문지
• /
• 제7권4호
• /
• pp.1-7
• /
• 2016

구조적 MRI 영상은 여러 단 변량과 다변량 방법을 위해 그레이 메터 (GM), 화이트 메터 (WM), 뇌척수액 (CSF) 세션화 과정을 하고 난후 형태계측학적 특징을 추출하기 위해 사용한다. 새로운 접근 방법은 매우 가벼운 알츠하이머 병에서 가벼운 알츠하이머병의 진단을 위해 적용된다. 간이정신상태검사에 따른 형태계측학적 특징과 가우시안 복합 모델 파라미터를 결합하여 정상인으로부터 알츠하이머 병 환자로 분류하는 방법을 제안한다. 결합한 특징은 주성분 분석 기법을 이용한 고차원의 저주를 제거한 후 다중 커널 SVM 분류기에 공급한다. 제안한 진단 방법의 실험적 결과는 90%이상의 특성도와 고민감도에 따라 다중 커널 SVM을 가진 층화 정확도가 96%까지 최대 산출한다.

• 복식문화연구
• /
• 제1권2호
• /
• pp.159-179
• /
• 1993

The purpose of this study is to collect data for he improvement of the accuracy of upper garments construction of the old whose bodies have been changed due to their age. In this study the body measurements with 61 items were taken from 226 men(aged fro m 60 to 80) living in Seoul by the R. Martin's method in 1992. The data were calculate by computer and analyzed by the multivariate method, especially factor and cluster analysis. The results of the study were as follows; 1. The average stature of elderly males was 163.6cm, chest circumference 91.6cm, waist circumference 9\\85.5cm. hip circumference 92.8cm, neck circumference 37cm, arm length 55.4 cm, back length 42.6cm, shoulder breadth 42.9cm and the Roher's Index 1.39, which was a standard body shape. 2. The items of factor analysis were explained to seven, namely, the degree of fatness of the upper body, the size of the frame of body, the length of the upper body, the degree of curve of the front body, the size of shoulder, the shape of the back, and the slope of shoulder. 3. The body types of subjects were classified into four types. The majority was type 4, which was 67% of subjects and considered as balanced body type. The distinctive features of those types are as follows; Type 1. The subjects of this type had a slight skeletal structure and were the thinnest of all the subjects with thin and forward-bent arm. Type 2. The subjects of this type were the tallest of all the subjects. they had the straightest side of body and a well-developed upper arm. The thigh length of this type was longer than the length of trunk. Type. 3. The subjects of this type was only one, so ti could be excluded. Type 4. The subjects of this type had a long trunk, well-developed shoulder, and a crook in their neck and back. The arm length and thigh of this type were short and those circumferences were thick. Type 5. The subjects of this type were the shortest of all, but had the highest degree of fatness in the waist and abdominal. They had well-developed front muscles of body and projected hip.

• 한국대기환경학회지
• /
• 제14권6호
• /
• pp.631-642
• /
• 1998

Fall-out particles were collected by the modified British deposit gauges at 35 sampling sites in Suwon area from January to November, 1996. Twenty chemical species (Al. Ba, Cd, Cr, K, Pb, Sb, Zn, Cu, Fe, Ni, V, F-, Cl-, NO3-, 5042-, Na+, NH4+, Mg2+, and Ca2+) were analyzed by AAS and If. The purposes of this study were to estimate qualitatively various emission sources of the fell-out particle by applying multivariate statistical techniques such as factor analysis, multiple regression analysis, and discriminant analysis. During the study, outlier sites were determined by a z-score method. Cl-, Na+, Mg2+, and SO42- were highly correlated due to their common marine related source. Wind speed was the most influential factor for the deposition fluxes of the particle itself and all the chemical species as well. When applying the factor analysis, 8 source patterns were qualitatively obtained, such as marine source, soil source, oil burning source, Cr related source, tire source, Cd related source, agriculture source, and F- related source. As a result of the multiple regression analysis, we could suggest that some chemical compounds may possibly exist in the form of CaSO4, NaN03, NaCl, MgC12, (NH4)2SO4, NaF, and CaCl2 in the fall-out particles. Finally, spatial and seasonal classification study performed by a discriminant analysis showed th.at SO42-, Ca2+, Cl-, and Fe were dominant in the group of spatial pattern; however, SO42-, Cl-, Al, and V were in the group of seasonal pattern.

• Journal of Nutrition and Health
• /
• 제36권7호
• /
• pp.769-776
• /
• 2003

This study has analyzed the association of physical activity and television watching time with obesity in 30-50 aged women from middle income town in Busan city area. Data were obtained using a questionnaire, including information about physical activity, TV watching time and health habit; social data regarding educational level and monthly income; family history of chronic condition. Height and weight were measured. Outcome variable was obesity, defined as a body mass index 25 kg/m$^2$ or greater. Odds ratios (OR) for obesity were estimated by multivariate logistic regression, and interpreted as a relative risk of obesity. The prevalence of obesity was 11.8%. The mean BMI of obese women was 26.9 kg/m$^2$. The OR of obesity was higher in subject of 40s than 30s. Subjects who had higher educational level presented lower OR than those of elementary or middle school education. Family income was not associated with obesity. Women having a family history of chronic condition had higher risk of obesity than those who did not have it. The OR was lower in active people at work (OR = 0.51; 95% CI = 0.26 - 0.98) than in inactive ones, and the ORs associated with regular exercise or activity at leisure time were not statistically different. However, subjects watching TV $\geq$ 3.5 hr/day showed higher OR (OR = 2.34; 95% CI = 1.16 - 4.74), compared with those watching TV $\geq$ 1.5 hr/day. Association of the joint classification of physical activity variables with obesity was estimated. The highest relative risk of 5.99 was in women in physically inactive at work and high category of TV watching ($\geq$ 3.5 hr/day). Even in women in active at work, the watching TV $\geq$ 3.5 hr/day made them have the high OR (OR = 2.44; 95% CI = 1.03 - 5.77). And at each time level of TV watching, the increasing activity level at work was associated with lower OR for obesity. These findings suggest that both TV watching time and physical activity at work were related to obesity in adult female, each with independent effects on obesity. TV watching time seems to be a significant factor that could partly evaluate the energy expenditure.

• Journal of Korean Neurosurgical Society
• /
• 제49권1호
• /
• pp.26-30
• /
• 2011

Objective: The primary objective of this study was to perform a retrospective evaluation of the radiological and pathological features influencing the formation of peritumoral brain edema (PTBE) in meningiomas. Methods: The magnetic resonance imaging (MRI) and pathology data for 86 patients with meningiomas, who underwent surgery at our institution between September 2003 and March 2009, were examined. We evaluated predictive factors related to peritumoral edema including gender, tumor volume, shape of tumor margin, presence of arachnoid plane, the signal intensity (SI) of the tumor in T2-weighted image (T2WI), the WHO histological classification (GI, GII/GIII) and the Ki-67 antigen labeling index (LI). The edema-tumor volume ratio was calculated as the edema index (EI) and was used to evaluate peritumoral edema. Results: Gender (p=0.809) and pathological finding (p=0.084) were not statistically significantly associated with peritumoral edema by univariate analysis. Tumor volume was not correlated with the volume of peritumoral edema. By univariate analysis, three radiological features, and one pathological finding, were associated with PTBE of statistical significance: shape of tumor margin (p=0.001), presence of arachnoid plane (p=0.001), high SI of tumor in T2WI (p=0.001), and Ki-67 antigen LI (p=0.049). These results suggest that irregular tumor margins, hyperintensity in T2WI, absence of arachnoid plane on the MRI, and high Ki-67 LI can be important predictive factors that influence the formation of peritumoral edema in meningiomas. By multivariate analysis, only SI of the tumor in T2WI was statistically significantly associated with peritumoral edema. Conclusion: Results of this study indicate that irregular tumor margin, hyperintensity in T2WI, absence of arachnoid plane on the MRI, and high Ki-67 LI may be important predictive factors influencing the formation of peritumoral edema in meningiomas.

• Asian Pacific Journal of Cancer Prevention
• /
• 제13권6호
• /
• pp.2639-2642
• /
• 2012

Background: The patterns of gastric cancer recurrence vary across societies. We designed the current study in an attempt to evaluate and reveal the outbreak of the recurrence patterns of gastric cancer and also prediction of time to recurrence and its effected factors in Iran. Materials and Methods: This research was performed from March 2003 to February 2007. Demographic characteristics, clinical and pathological diagnosis and classification including pathologic stage, tumor grade, tumor site and tumor size in of patients with GC recurrent were collected from patients' data files. To evaluate of factors affected on the relapse of the GC patients, gender, age at diagnosis, treatment type and Hgb were included in the research. Data were analyzed using Kaplan-Meier and logistic regression models. Results: After treatment, 82 patients suffered recurrence, 42, 33 and 17 by the ends of first, second and third years. The mean ( SD) and median ( IQR) time to recurrence in patients with GC were 25.5 (20.6-30.1) and 21.5 (15.6-27.1) months, respectively. The results of multivariate analysis logistic regression showed that only pathologic stage, tumor grade and tumor site significantly affected the recurrence. Conclusions: We found that pathologic stage, tumor grade and tumor site significantly affect on the recurrence of GC which has a high positive prognostic value and might be functional for better follow-up and selecting the patients at risk. We also showed time to recurrence to be an important factor for follow-up of patients.

• 약학회지
• /
• 제53권2호
• /
• pp.51-59
• /
• 2009

Quantitative analysis of (+)-catechin (C), (-)-epigallocatechin (EGC), (-)-epicatechin (EC), (-)-epigallocatechin gallate (EGCG), (-)-epicatechin gallate (ECG) and caffeine in commercial green tea was carried out by HPLC employing gradient elution of 0.1% acetic acid and acetonitrile on ODS column. The optimized HPLC method provided satisfactory linearity, accuracy and precision. The relationship between the concentration of the components and cultivated region of the commercial green tea was not significant, while the concentration of EGCG, ECG and caffeine decreased significantly in the later harvested green tea samples (p<0.01). Multivariate analysis of the components was performed in order to characterize and evaluate the cultivated region and harvest period-related variation. Hierarchical clustering and discriminant analysis were applied to classify the geographical and seasonal origins of the green tea samples. The classification accuracy of the cultivated region and harvest period by discriminant analysis was 95% and 91%, respectively, indicating that this method could be reliable and convenient for the quality control of herbal products with different origin.

• Journal of Ginseng Research
• /
• 제44권6호
• /
• pp.775-783
• /
• 2020

Background: The reports about valuable oligosaccharides in ginseng are quite limited. There is an urgent need to develop a practical procedure to detect and analyze ginseng oligosaccharides. Methods: The oligosaccharide extracts from ginseng were permethylated by solid-phase methylation method and then were analyzed by ultra-high-performance liquid chromatography-Q-Orbitrap/MS. The sequence, linkage, and configuration information of oligosaccharides were determined by using accurate m/z value and tandem mass information. Several standard references were used to further confirm the identification. The oligosaccharide composition in white ginseng and red ginseng was compared using a multivariate statistical analysis method. Results: The nonreducing oligosaccharide erlose among 12 oligosaccharides identified was reported for the first time in ginseng. In the comparison of the oligosaccharide extracts from white ginseng and red ginseng, a clear separation was observed in the partial least squares-discriminate analysis score plot, indicating the sugar differences in these two kinds of ginseng samples. The glycans with variable importance in the projection value large than 1.0 were considered to contribute most to the classification. The contents of oligosaccharides in red ginseng were lower than those in white ginseng, and the contents of maltose, maltotriose, maltotetraose, maltopentaose, maltohexaose, maltoheptaose, maltooctaose, maltononaose, sucrose, and erlose decreased significantly (p < 0.05) in red ginseng. Conclusion: A solid-phase methylation method combined with liquid chromatography-tandem mass spectrometry was successfully applied to analyze the oligosaccharides in ginseng extracts, which provides the possibility for holistic evaluation of ginseng oligosaccharides. The comparison of oligosaccharide composition of white ginseng and red ginseng could help understand the differences in pharmacological activities between these two kinds of ginseng samples from the perspective of glycans.

• 박물관보존과학
• /
• 제2권
• /
• pp.69-76
• /
• 2000

본 연구는 동남해안 및 도서지방의 신석기시대 주칠토기 23점에 대한 과학적 분석의 일환으로서 먼저 태토성분, 소성온도, 안료성분 및 안료두께를 분석한 데에 이어 태토성분에 대한 통계적인 고찰 및 경도분석을 통한 안료성분의 역할을 보강하여 재정리한 것이다. 유도결합플라즈마분광기(ICP-AES)와 엑스선형광분석기(XRF)를 사용하여 태토의 성분분석을 실시하였고, 이 분석결과에 대한 다변량해석(PCA : 주성분분석법)을 수행한 결과, 토기의 태토는 범방, 욕지도, 나머지 지역의 3개 군으로 분류되었다. 또 태토와 안료의 경도를 토기 표면으로부터 깊이별로 측정한 결과, 산화철이 다량 포함된 안료층의 경도가 태토층보다 높았고 이를 통해 산화철이 고온소성시 경도를 크게 하는 역할을 했음을 알 수 있었다. 또한 안료층의 경도가 태토층 보다 높은 것은 안료층도 소성되었음을 의미하는 것으로, 토기성형시 안료를 먼저 바른 후 토기가 구워졌음을 유추해 볼 수 있다.

• 대한토목학회논문집
• /
• 제36권5호
• /
• pp.915-926
• /
• 2016

본 연구는 도시지역 토사재해 위험지역에 대한 특성을 살펴보고, 다변량 통계분석을 이용하여 위험지역들을 유형화하여 관리전략상의 시사점을 도출한다. 사례분석은 서울시 산재된 토사재해 위험지역 49개소 현장조사 표본자료를 대상으로 하며, 조사항목의 특성정보를 이용하여 분석을 수행하였다. 분석 결과, 도시지역 토사재해 위험지역에는 계류부 하단 주변에 공원, 택지, 도로 등이 주로 위치하고 있으며, 다수의 주택가가 위험 지역과 인접해 있음을 알 수 있었다. 또한 군집분석과 판별분석을 통해 토사재해 위험지역은 크게 2가지 유형으로 구분되며, 위험지역에 대해 중점적으로 고려해야 할 요소는 주변 토지이용과 비탈면 경사임을 확인하였다. 이들 인자를 근거로 각 유형별 특성을 고려한 도시지역 토사재해 관리전략 상의 시사점을 도출하였다. 본 연구에서 제시한 분석방법과 관리전략상의 시사점은 기존의 산지 중심의 위험지역 관리대책에 더하여 피해 영향권에 해당하는 시가지에 대한 관리대책을 고려함으로써 토사재해에 보다 효과적으로 대응할 수 있는 기초가 될 수 있을 것으로 기대된다.