• 제목/요약/키워드: multiple weights

검색결과 298건 처리시간 0.027초

Organic matrix-free imaging mass spectrometry

  • Kim, Eunjin;Kim, Jisu;Choi, Inseong;Lee, Jeongwook;Yeo, Woon-Seok
    • BMB Reports
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    • 제53권7호
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    • pp.349-356
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    • 2020
  • Mass spectrometry (MS) is an ideal tool for analyzing multiple types of (bio)molecular information simultaneously in complex biological systems. In addition, MS provides structural information on targets, and can easily discriminate between true analytes and background. Therefore, imaging mass spectrometry (IMS) enables not only visualization of tissues to give positional information on targets but also allows for molecular analysis of targets by affording the molecular weights. Matrix-assisted laser desorption/ionization-time of flight (MALDI-TOF) MS is particularly effective and is generally used for IMS. However, the requirement for an organic matrix raises several limitations that get in the way of accurate and reliable images and hampers imaging of small molecules such as drugs and their metabolites. To overcome these problems, various organic matrix-free LDI IMS systems have been developed, mostly utilizing nanostructured surfaces and inorganic nanoparticles as an alternative to the organic matrix. This minireview highlights and focuses on the progress in organic matrix-free LDI IMS and briefly discusses the use of other IMS techniques such as desorption electrospray ionization, laser ablation electrospray ionization, and secondary ion mass spectrometry.

The Effect of Sub-division (Two or Three Sub-populations) of a Population on Genetic Gain and Genetic Diversity

  • Oikawa, T.;Matsui, H.;Sato, K.
    • Asian-Australasian Journal of Animal Sciences
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    • 제15권6호
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    • pp.767-771
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    • 2002
  • Breeding efficiencies were compared among three population schemes: a single population, a population with two subpopulations and a population with three sub-populations. A simulation experiment of selection was carried out for 10 generations with 20 replications each by comparing average breeding values and inbreeding coefficients among the three population schemes. Phenotypes of three traits were generated with a model comprising 36 loci, each with additive genetic effects and residuals distributed normally. Among the three population schemes, the single population scheme was definitely superior to the other two with regards to selection response and inbreeding. The multiple sub-population scheme was, however, considered to be an alternative population scheme when the difference in economic weights of the traits was small among the sub-populations, assuming moderate inbreeding depression for traits and crossbreeding. The scheme with two sub-populations had a higher genetic value than that with three subpopulations; however, the genetic values of the schemes were comparable when maternal heterosis was taken into account. The choice of population schemes may depend on the cost-sharing policy between the breeding population and the commercial population rather than just the breeding efficiency.

한국 노인의 영양부족위험 진단을 위한 간이조사표의 개발 (Development of a Simple Screening Test for Identifying Korean Elderly at Risk of Undernutrition)

  • 김기남;현태선;이정원
    • 대한지역사회영양학회지
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    • 제5권3호
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    • pp.475-483
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    • 2000
  • The develop a simple screening test for identifying Korean elderly at risk of undernutrition, the data of the health-related habits, dietary behaviors and nutrient intakes of the elderly in Chongju were analyzed. Two risk indicators, mean adequacy ratio (MAR) and the respondents perceived health, were used to detect the undernutrition risk of the elderly. In order to select a list of questions for the test, factors a affecting nutritional status and items investigated in previous nutrition surveys of the elderly were considered, and 21 questions were primarily selected. A multiple regression and stepwise regression analysis were used to take out the weak predictors of poor nutrient intake, and to give item weights to the strong predictors, and a list of 17 questions was finally adopted. To determine the cut-point of the test score, sensitivity, and positive predictive values were calculated. The Simple Screening Test developed in this study is a brief, easily scored tool to predict poor nutrient intake and the perceived health status of the elderly. The test may provide a basis of further comprehensive nutritional assessment or intervention planning, if necessary, for those who are diagnosed ad "high risk". The test, however, needs to be independently validated by other groups of individuals.dividuals.

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A New Connected Coherence Tree Algorithm For Image Segmentation

  • Zhou, Jingbo;Gao, Shangbing;Jin, Zhong
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • 제6권4호
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    • pp.1188-1202
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    • 2012
  • In this paper, we propose a new multi-scale connected coherence tree algorithm (MCCTA) by improving the connected coherence tree algorithm (CCTA). In contrast to many multi-scale image processing algorithms, MCCTA works on multiple scales space of an image and can adaptively change the parameters to capture the coarse and fine level details. Furthermore, we design a Multi-scale Connected Coherence Tree algorithm plus Spectral graph partitioning (MCCTSGP) by combining MCCTA and Spectral graph partitioning in to a new framework. Specifically, the graph nodes are the regions produced by CCTA and the image pixels, and the weights are the affinities between nodes. Then we run a spectral graph partitioning algorithm to partition on the graph which can consider the information both from pixels and regions to improve the quality of segments for providing image segmentation. The experimental results on Berkeley image database demonstrate the accuracy of our algorithm as compared to existing popular methods.

Acoustic Signal based Optimal Route Selection Problem: Performance Comparison of Multi-Attribute Decision Making methods

  • Borkar, Prashant;Sarode, M.V.;Malik, L. G.
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • 제10권2호
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    • pp.647-669
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    • 2016
  • Multiple attribute for decision making including user preference will increase the complexity of route selection process. Various approaches have been proposed to solve the optimal route selection problem. In this paper, multi attribute decision making (MADM) algorithms such as Simple Additive Weighting (SAW), Weighted Product Method (WPM), Analytic Hierarchy Process (AHP) method and Total Order Preference by Similarity to the Ideal Solution (TOPSIS) methods have been proposed for acoustic signature based optimal route selection to facilitate user with better quality of service. The traffic density state conditions (very low, low, below medium, medium, above medium, high and very high) on the road segment is the occurrence and mixture weightings of traffic noise signals (Tyre, Engine, Air Turbulence, Exhaust, and Honks etc) is considered as one of the attribute in decision making process. The short-term spectral envelope features of the cumulative acoustic signals are extracted using Mel-Frequency Cepstral Coefficients (MFCC) and Adaptive Neuro-Fuzzy Classifier (ANFC) is used to model seven traffic density states. Simple point method and AHP has been used for calculation of weights of decision parameters. Numerical results show that WPM, AHP and TOPSIS provide similar performance.

Design of a Planar Slotted Waveguide Array Antenna for X-band Radar Applications

  • Bhatti, Rashid Ahmad;Park, Byeong-Yong;Im, Yun-Taek;Park, Seong-Ook
    • Journal of electromagnetic engineering and science
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    • 제11권2호
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    • pp.97-104
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    • 2011
  • A planar slotted waveguide array antenna has been designed at 9.37 GHz for X-band radar applications. The antenna consists of multiple branchline waveguides with broadwall radiating shunt slots and a main waveguide to feed the branch waveguides through a series of inclined coupling slots. The antenna feed point is located at the center of the main waveguide. Element weights in the array have been calculated bysampling a continuous circular Taylor aperture distribution at the 25 dB sidelobe level in both the E and Hplanes. A commercially available electromagnetic (EM) simulation tool has been used to characterize the individual isolated slot and that data hassubsequently been used to design the planar array. The array is finally analyzed in a CST Microwave studio and the measured and simulated results have been found to be in good agreement.

지진력을 받는 해양케이블의 동적 비선형해석 (Dynamic Non-Linear Analysis of Ocean Cables Subjected to Earthquakes)

  • 김남일;신현목
    • 한국지진공학회논문집
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    • 제3권2호
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    • pp.77-86
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    • 1999
  • 이전의 연구에서 하중증분법을 이용하여 지점 변위를 일으키고 자중. 부력, 그리고 조류력을 받는 해양케이블의 초기평형 상태를 결정하였다 본 연구에서는 이 상태를 기준으로 동적으로 지점운동 또는 지진하중에 대하여 첨가질량 및 케이블운동에 의한 Morison force를 고려한 해양케이블의 동적 비선형해석을 수행한다 지점운동과 지진력을 받는 수중케이블에 대하여 기하학적인 비선형해석을 수행하고 해석결과의 분석을 통하여 해양케이블의 동특성을 파악한다.

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ANP 모형을 이용한 금융기업의 옴니채널 고객 시스템의 중요 구축 요소 분석 (A Study for Analysing Key Factors for Establishing the Omni-Channel Customer System in a Financial Enterprise Using ANP)

  • 황현천;김우제
    • 산업경영시스템학회지
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    • 제43권1호
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    • pp.50-60
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    • 2020
  • The omni-channel customer system is the communication system between enterprise and customer via multiple channels such as mail, email, SMS, and mobile. The omni-channel customer system complements each other channel through the integration of each channel. The purpose of this research is to derive key factors and calculate the weights that a financial enterprise considers when adopting the omni-channel customer system. For this research, we analyzed the request for proposal documents used for the omni-channel customer system implementation projects in the financial enterprise. Also, we derived, classified, and stratified the key factors to be considered for the introduction of the omni-channel customer system in the financial enterprise. As a result of analyzing the key factors, customer experience, operations, and security were identified as the components of the top category in introducing the omni-channel customer system in the financial sector. Furthermore, the weight for each key factor was calculated by using ANP. As a result of ANP, operations, customer experience, and security were important in order. Also, the degree of easiness for connecting with other systems and the various abilities for representing the contents of the omni-channels were derived as the important key factors.

Critical Factors Affecting Construction Price Index: An Integrated Fuzzy Logic and Analytical Hierarchy Process

  • NGUYEN, Phong Thanh;NGUYEN, Quyen Le Hoang Thuy To
    • The Journal of Asian Finance, Economics and Business
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    • 제7권8호
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    • pp.197-204
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    • 2020
  • Nowadays, many construction engineering and technology enterprises are evolving to find that prosperity is driven and inspired by an open economy with dynamic markets and fierce multifaceted competition. Besides brand and product uniqueness, the ability to quickly provide customers with quotes are matters of concern. Such a requirement for prompt cost estimation of construction investment projects with the use of a construction price index poses a significant challenge to contractors. This is because the nature of the construction industry is shaped by changes in domestic and foreign economic factors, socio-financial issues, and is under the influence of various micro and macro factors. This paper presents a fuzzy decision-making approach for calculating critical factors that affect the construction price index. A qualitative approach was implemented based on in-depth interviews of experts in the construction industry in Vietnam. A synthetic comparison matrix was calculated using Buckley approach. The CoA approach was applied to defuzzified the fuzzy weights of factors that affect the construction price index. The research results show that the top five critical factors affecting the construction price index in Vietnam are (1) consumer price index, (2) gross domestic product, (3) basic interest rate, (4) foreign exchange rate, and (5) total export and import.

웹 기반 정보보안 수준 측정 도구 설계 (Web-Based Information Security Leveling Tool)

  • 성경
    • 한국컴퓨터정보학회논문지
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    • 제10권4호
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    • pp.375-384
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    • 2005
  • 정보통신기술이 발달함에 따라 보안 사고가 증가로 조직의 효율적인 보안 관리를 위한 보안수준 측정에 대한 방법과 도구개발의 필요성이 요구되고 있다. 그러나 외국의 연구는 대부분 수준 측정을 위한 항목구성이 우리 조직의 실정에 맞지 않고 또한 도구 역시 사용의 편이성이나 경제성을 제공하지 못하고 있으며, 국내의 연구 또한 보안수준 측정 시 조직의 특성을 적절히 감안하지 못하고 있다. 따라서 본 논문에서는 다중 가중치를 조직의 특성에 따라 가변적으로 적용하고 수준 측정자의 주관성을 감소시키기 위하여 퍼지기법과 비용 한계의 범위 안에서 보안 대책의 수립을 위해 유전 알고리즘을 적용한 효율적인 보안 수준측정 도구를 제안하고자 한다.

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