• 한국의학물리학회지:의학물리
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• 제29권2호
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• pp.53-58
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• 2018

This paper evaluates patient-specific quality assurance (PSQA) in the treatment of small and multiple tumors by the CyberKnife system with fixed collimators, using an ion chamber and EBT3 films. We selected 49 patients with single or multiple brain tumors, and the treatment plans include one to four targets with total volumes ranging from 0.12 cc to 3.74 cc. All PSQA deliveries were performed with a stereotactic dose verification phantom. The A16 microchamber (Standard Imaging, WI, USA) and Gafchromic EBT3 film (Ashland ISP Advanced Materials, NJ, USA) were inserted into the phantom to measure the point dose of the target and the dose distribution, respectively. The film was scanned 1 hr after irradiation by a film digitizer scanner and analyzed using RIT software (Radiological Imaging Technology, CO, USA). The acceptance criteria was <5% for the point dose measurement and >90% gamma passing rate using 3%/3 mm and relative dose difference, respectively. The point dose errors between the calculated and measured dose by the ion chamber were in the range of -17.5% to 8.03%. The mean point dose differences for 5 mm, 7.5 mm, and 10 mm fixed cone size was -11.1%, -4.1%, and -1.5%, respectively. The mean gamma passing rates for all cases was 96.1%. Although the maximum dose distribution of multiple targets was not shown in the film, gamma distribution showed that dose verification for multiple tumors can be performed. The use of the microchamber and EBT3 film made it possible to verify the dosimetric and mechanical accuracy of small and multiple targets. In particular, the correction factors should be applied to small fixed collimators less than 10 mm.

• 한국항공우주학회지
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• 제39권9호
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• pp.848-857
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• 2011

영상센서 기반의 충돌회피 시스템을 구성하기 위해서는 수 픽셀 이내의 낮은 신호대잡음비 환경에서 다수의 표적을 탐지할 수 있는 알고리듬이 필요하다. 이처럼 영상 내에서 희미하게 나타나는 잠재적인 표적과 잡음을 구분하기 위한 방법으로서 연속적인 영상 정보를 효율적으로 처리하는 Track-Before-Detect (TBD) 알고리듬이 연구되고 있다. 본 논문에서는 기존의 TBD 알고리듬을 확장하여 다수 표적 탐지 요구조건을 만족시키기 위한 두 가지 방식의 기법을 제시하였다. 첫 번째 방식은 동적 계획법과 K-평균 클러스터링 기법에 기반을 두고 있으며 두 번째 방식은 은닉 마르코프 모델에 Sub-Window 기법을 적용하였다. 제안한 방식의 성능 및 차이점은 수치해석 결과를 통해 분석하였다.

• 전기학회논문지
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• 제56권10호
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• pp.1826-1835
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• 2007

In this paper, we present a new approach for automatic detection and tracking for multiple targets. We combine a highest probability data association(HPDA) algorithm for target detection with a particle filter for multiple target tracking. The proposed approach evaluates the probabilities of one-to-one assignments of measurement-to-track and the measurement with the highest probability is selected to be target- originated, and the measurement is used for probabilistic weight update of particle filtering. The performance of the proposed algorithm for target tracking in clutter is compared with the existing clustering algorithm and the sequential monte carlo method for probability hypothesis density(SMC PHD) algorithm for multi-target detection and tracking. Computer simulation studies demonstrate that the HPDA algorithm is robust in performing automatic detection and tracking for multiple targets even though the environment is hostile in terms of high clutter density and low target detection probability.

• Advances in Computational Design
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• 제2권3호
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• pp.241-256
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• 2017

This paper introduces the process for Multi-objective Optimization Framework (MOF) which mediates multiple conflicting design targets. Even though the extensive researches have shown the benefits of optimization in engineering and design disciplines, most optimizations have been limited to the performance-related targets or the single-objective optimization which seek optimum solution within one design parameter. In design practice, however, designers should consider the multiple parameters whose resultant purposes are conflicting. The MOF is a BIM-integrated and simulation-based parametric workflow capable of optimizing the configuration of building components by using performance and non-performance driven measure to satisfy requirements including build programs, climate-based daylighting, occupant's experience, construction cost and etc. The MOF will generate, evaluate all different possible configurations within the predefined each parameter, present the most optimized set of solution, and then feed BIM environment to minimize data loss across software platform. This paper illustrates how Multi-objective optimization methodology can be utilized in design practice by integrating advanced simulation, optimization algorithm and BIM.

• Journal of Ginseng Research
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• 제42권1호
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• pp.98-106
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• 2018

Panax ginseng has been used since ancient times based on the traditional Asian medicine theory and clinical experiences, and currently, is one of the most popular herbs in the world. To date, most of the studies concerning P. ginseng have focused on specific mechanisms of action of individual constituents. However, in spite of many studies on the molecular mechanisms of P. ginseng, it still remains unclear how multiple active ingredients of P. ginseng interact with multiple targets simultaneously, giving the multidimensional effects on various conditions and diseases. In order to decipher the systems-level mechanism of multiple ingredients of P. ginseng, a novel approach is needed beyond conventional reductive analysis. We aim to review the systems-level mechanism of P. ginseng by adopting novel analytical framework-network pharmacology. Here, we constructed a compound-target network of P. ginseng using experimentally validated and machine learning-based prediction results. The targets of the network were analyzed in terms of related biological process, pathways, and diseases. The majority of targets were found to be related with primary metabolic process, signal transduction, nitrogen compound metabolic process, blood circulation, immune system process, cell-cell signaling, biosynthetic process, and neurological system process. In pathway enrichment analysis of targets, mainly the terms related with neural activity showed significant enrichment and formed a cluster. Finally, relative degrees analysis for the target-disease association of P. ginseng revealed several categories of related diseases, including respiratory, psychiatric, and cardiovascular diseases.

• 한국항행학회논문지
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• 제1권1호
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• pp.35-46
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• 1997

다중 표적의 추적은 과거 10여년 동안 레이다 용용분야에서 큰 주목을 받아 왔으며 많은 학술회의와 논문발표의 중심 과제가 되어왔다. 이 문제를 해결하기 위하여 여러 가지 추적방식들이 제시되어 왔다. 그 중 대표적인 것으로는 Nearest Neighbor (NN) 방식에 의한 비확률적인 짝배정(association) 방법과 확률적인 표적모형에 기초한 Multiple Hypothesis Test (MHT) 방식 및 Joint Probabilistic Data Association (JPDA) 방식으로 대별할 수 있다. 이러한 여러 가지 방식들은 각기 그 장점 및 단점을 가지게 되어 계산속도나 표적의 추적정확도에 있어서 큰 차이를 나타내게 된다. 본 논문에서는 NN방식, MHT 방식 및 JPDA 필터에 기초한 세 가지 추적 알고리듬을 비교하고, 시뮬레이션을 통하여 다중 기동 표적에 대하여 그 추적성능을 분석한다.

• 한국표면공학회:학술대회논문집
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• 한국표면공학회 2017년도 춘계학술대회 논문집
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• pp.95.1-95.1
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• 2017

In this study, it has been tried to make the single Mo-Cu alloying targets with the Cu showing the best surface hardness that was determined by investigation on the coatings with the double target process. The single alloying targets were prepared by powder metallurgy methods such as mechanical alloying and spark plasma sintering. The nanocomposite coatings were prepared by reactive magnetron sputtering process with the single alloying targets in $Ar+N_2$ atmosphere. The microstructure changes of the Mo-Cu-N coatings with diverse Cu contents were investigated by using XRD, SEM and EDS. The mechanical properties of the coatings were evaluated by using nano-indentor, scratch test, and ball on disc methods. Especially, the coated samples were tested by using various lubricating oil to compare the property of anti wear-resistance. In this study, the nano-composite MoN-Cu coatings prepared using an alloying target was eventually compared with the coatings from the multiple targets.

• 한국군사과학기술학회지
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• 제14권3호
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• pp.517-523
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• 2011

The estimation filter in radar systems must track targets' position within low tracking error. In the Multi-Function Radar(MFR), ${\alpha}-{\beta}$ filter and Kalman filter are widely used to track single or multiple targets. However, due to target maneuvering, these filters may not reduce tracking error, therefore, may lost target tracks. In this paper, a target tracking filter based on particle filtering algorithm is proposed for the MFR. The advantage of this method is that it can track targets within low tracking error while targets maneuver and reduce impoverishment of particles by the proposed resampling method. From the simulation results, the improved tracking performance is obtained by the proposed filtering algorithm.

• Journal of Electrical Engineering and Technology
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• 제13권3호
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• pp.1377-1382
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• 2018

In the marine environment, many clutters have similar features with the marine targets due to the diverse changes of the air temperature, water temperature, various weather and seasons. Also, the clutters in the ground environment have similar features due to the same reason. In this paper, we proposed a robust Hybrid Machine Character (HMC) method to classify the targets from the clutters in the infrared images for the various environments. The proposed HMC method adopts human's multiple personality utilization and the CNN ensemble method to classify the targets in the ground and marine environments. This method uses an advantage of the each environmental training model. Experimental results demonstrate that the proposed method has better success rate to classify the targets and clutters than previously proposed CNN classification method.

• 한국전자파학회논문지
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• 제26권9호
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• pp.806-813
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• 2015

차량용 레이더(automotive radar)는 크기, 무게, 비용 등의 문제로 적은 수의 수신 채널을 가진 안테나를 사용한다. 이때, 스펙트럼 추정 기법 중 하나인 relaxation(RELAX) 기법을 이용하면, 표적의 방위각뿐만 아니라, 빔 내에 존재하는 표적의 개수 추정 또한, 가능하다. 하지만, 차량용 레이더의 적은 수신 채널 개수로 인하여, 정밀하지 않은 각도 영역에서의 스펙트럼 추정이 이루어지며, 이는 부정확한 방위각 추정 성능을 야기한다. 이를 개선하기 위해 본 논문에서는 minimum length description(MDL) 기준을 통한 표적 개수의 추정과 결부한 root-multiple signal classification(root-MUSIC) 기법을 이용하여 표적의 정확한 방위각을 추정하도록 제안한다. 시뮬레이션에서는 세 점 표적들이 안테나 빔 내에 존재할 때, 제안한 방법이 더 나은 방위각 추정 결과를 도출할 수 있음을 보인다.