• Asian Pacific Journal of Cancer Prevention
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• 제13권12호
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• pp.6087-6091
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• 2012

Context: Patients diagnosed with a cancer have a life time risk of developing another de novo malignancy depending on various inherited, environmental and iatrogenic risk factors. Of late the detection of new primary has increased mainly due to refinement in both diagnostic and treatment modalities. Cancer victims are surviving longer and thus are more likely to develop a new metachronous malignancy. Aims: To report our observed trend of increase in prevalence of both synchronous and metachronous second malignant neoplasms among cancer victims and to review the relevant literature. Settings and Design: A hospital based retrospective collection of prospective data of patients diagnosed with second denovo malignancy. Materials and Method: The study was conducted over a 5 year period from July 2008 to June 2012. All patients diagnosed with a histologically proven second malignancy as per Warren Gate's criteria were included. Various details regarding sex, age at presentation, synchronous or metachronous, treatment and outcome were recorded. Conclusions: The occurrence of multiple primary malignancies is not rare. Awareness of the possibility alerts the clinician in evaluation of patients with a known malignancy presenting with unusual sites of metastasis. Individualizing the treatment according to the stages of the primaries will result in durable cancer control particularly in synchronous double malignancy.

• 대한세포병리학회지
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• 제10권1호
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• pp.67-71
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• 1999

We report a case of 53-year-old man with plasmacytold transitional cell carcinoma of the urinary bladder, which may be confused with plasmacytoma. The patient initially presented with gross hematuria and dysuria for two months. Cystoscopy and radiologic studios revealed multiple intraluminal protruding masses on the urinary bladder invading perivesical fat tissue. After urinary cytologic examination and cystoscopic biopsy, radical cystectomy and pelvic lymph node dissections were done. Urine cytology showed single cells and poorly cohesive cells with round eccentric nuclei, bi-or multi-nucleation, indistinct nucleoli, coarse chromatin, and abundant basophilic cytoplasm within relatively clear background. The cytologic findings of tumor cells were similar to the plasma cells seen in plasmacytoma. The tumor of the bladder was composed on discohesive, individual cancer cells with diffuse pattern that simulated lymphoma or plasmacytoma. Immunohistochemical and electron microscopic studies clearly established the epithelial nature of the neoplasm. Recognition of this plasmacytoid type of transitional cell carcinoma of the urinary bladder can avoid the misdiagnosis.

• 대한한방내과학회지
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• 제39권2호
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• pp.268-276
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• 2018

Although patients with breast cancer receive standard treatments, they often experience recurrence or metastasis of tumors. Therefore, patients seeking treatment with traditional Korean medicine (TKM) in addition to conventional treatment have increased. We present a case of 46-year-old female with recurring breast cancer. She underwent surgeries and various hormone therapies since being diagnosed in 2007. Upon follow-up examination, she had metastatic lesions on the lung and multiple bones in 2015 and 2016. She received TKM treatments from May 2017 with Aromasin and Afinitor. However, hepatic metastasis was found after two months, so she started Capecitabine with TKM. After about two months, the liver nodules disappeared and a seeding nodule in the right paracolic gutter was decreased. After two months, the tumor response was stable disease. Back pain due to bone metastasis was improved. We suggest that combination treatment of TKM and chemotherapy is a promising method for treating breast cancer.

• Journal of Chest Surgery
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• 제37권2호
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• pp.184-187
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• 2004

식도와 폐에 동시성 중복암이 발생하는 경우는 드물다. 우폐 하엽과 흉부 식도에 원발성 편평상피세포암이 발생한 75세 남자 환자에 대해 우폐 하엽 절제술과 Ivor Lewis 술식을 동시에 시행하였다. 좌폐 상엽의 편평상피세포암으로 좌폐 상엽 절제술을 시행했던 69세 남자 환자에서 4개월 후 흉부 식도에 발생한 편평상피세포암에 대해 Ivor Lewis 술식을 시행하였다. 상기 2명의 환자는 수술 후 각각 10개월, 24개월째이며 재발 없이 잘 지내고 있다. 저자들은 식도와 폐에 발생한 동시성 중복암 2예에 대해 완전 절제를 시행하여 좋은 결과를 얻었기에 문헌고찰과 함께 보고하는 바이다.

• 성인간호학회지
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• 제28권4호
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• pp.378-387
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• 2016

Purpose: The purpose of this study was to describe the impact of fatigue and distress on self-efficacy among breast cancer survivors and to provide a base for development of nursing intervention strategy to improve self-efficacy. Methods: A descriptive research design was used. The subjects were 158 patients who were either being treated or were receiving follow-up care at a university breast center in D City from May 30 to August 30, 2014. Structured questionnaires, Revised Piper Fatigue Scale, Distress Thermometer, and Self-Efficacy Scale for Self-Management of Breast Cancer were used to measure fatigue, distress, and self-efficacy. Data were analyzed using t-test, ANOVA, Pearson's correlation coefficients, and multiple regressions. Results: The mean scores of fatigue, distress, and self-efficacy were 3.83, 4.31, and 3.77, respectively. There were significant differences among participants in terms of educational background, current treatment methods, perceived health status, economic burden for fatigue and perceived health status for distress. Self-efficacy was impacted by age, educational background, marital status, average monthly income, perceived health status, and medical expenses. Fatigue, age, and the burden on medical expense had the most impact on self-efficacy, accounting for 17% of the variance. Conclusion: Fatigue should be managed to improve self-efficacy of breast cancer survivors. Therefore, nursing programs designed to decrease fatigue may be helpful.

• 성인간호학회지
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• 제24권6호
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• pp.557-568
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• 2012

Purpose: This was a correlation study to identify the relationship of spiritual well-being, hope on fatigue in cancer patients on chemotherapy. Methods: The subjects completed structured questionnaires: the 'Spiritual Well-being Scale', developed by Paloutzian & Ellison, 'Hope Scale', developed by Kim & Lee and 'Fatigue Scale', developed by Mendoza et al. Data were collected from 120 patientsat two general hospitals and were analyzed using t-test, ANOVA & Sheffe's test, Pearson's correlation coefficients and multiple stepwise regression. Results: Participants with higher fatigue had lower scores for hope (r=-.36, p<.001) and lower scores for spiritual well-being (r=-.23, p=.011). Participants with higher scores for hope had higher scores for spiritual well-being (r=.61, p<.001). The factors seen as contributing to fatigue were hope, financial burden of treatment, period of religious life, living with spouse, and reported pain. These variables explained 32.3% of the variance in fatigue. Hope with 13% was the most influential. Conclusion: The fatigue of the cancer patients on chemotherapy can be reduced if hope is improved, and hope can be improved if the spiritual well-being is improved. Therefore, we suggest developing a nursing intervention program that leads to improve hope and spiritual well-being of the cancer patients on chemotherapy for reducing fatigue.

• Journal of Korean Neurosurgical Society
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• 제30권9호
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• pp.1127-1129
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• 2001

The vast majority of schwannomas occur on cranial nerves, and rarely in the retroperitoneum. Solitary schwannoma in the psoas muscle is extremely rare. The authors present a case of retroperitoneal neoplasm in the psoas muscle identified as schwannoma which is not associated with von Recklinghausen's disease. A 68 years old female patient was admitted because of low back pain and weakness at the left leg. CT and MRI revealed a large cystic mass with well-defined margin and multiple internal septation within the left psoas muscle. The tumor was totally extirpated and histologically confirmed as a schwannoma.

• 대한세포병리학회지
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• 제18권2호
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• pp.133-142
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• 2007

Cytologic diagnosis of the metastatic tumors to the thyroid is important in the management of the patients. There have been rare reports analyzing fine-needle aspiration (FNA) cytology of metastatic tumors to the thyroid. This study examines comprehensive cytologic findings of metastatic tumors to the thyroid with radiologic findings. The FNA cytology slides obtained from 12 cases with metastatic tumors of the thyroid; lung cancer (n=5), tongue and tonsil cancer (n=3), esophageal cancer (n=2), and breast cancer (n=2) were reviewed. Radiological study showed single mass with heterogeneous texture or multiple masses without calcification. Metastatic tumor was easily considered in a differential diagnosis of FNA cytology because they had peculiar cytological features which were not seen in primary thyroid tumor. The smear background varied from predominantly necrotic, bloody, and inflammatory to colloid. The aspirates exhibited a mixture of benign follicular cells and malignant cells in 6 cases. The characteristic cytoplasmic features of the tumor cells, such as keratin, mucin and melanin, were found in 9 cases. Although some cases mimic primary thyroid neoplasm, a careful examination of the cytological characteristics may help cytopathologists to recognize a metastatic tumor in the thyroid by FNA, and may help the clinicians to establish a proper treatment plan.

• Journal of Chest Surgery
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• 제31권4호
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• pp.422-426
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• 1998

53 세 남자가 하부 식도에서 발생한 거대한 용종성 종괴에 의한 연하곤란을 주소로 내원하여 식도 절제술과 식도-위 문합술을 시행하였다. 현미경소견상 기저세포양 편평세포암과 연골 분화가 여러 곳에서 관찰되는 연골육종이 혼재하는 진성암육종이었다. 위장주위 임파절과 기도분기부하 임파절에 편평세포암이 전이되어 있었다. 면역조직화학적 검사상 편평세포 지역은 cytokeratin 에 강한 양성이었고 기저세포양 지역은 고분자량 cytokeratin 에 양성이었다. 방추세포육종은 vimentin 과 smooth muscle actin 에 양성이었고 연골육종 지역은 vimentin 과 S-100 단백질에 양성이었다. 술후 항암제 치료와 방사선 치료의 보조병용요법을 시행하였으며 술후 11 개월인 현재까지 재발의 소견 없이 정상 식사를 하고 있다.

• 한국어병학회지
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• 제22권2호
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• pp.107-113
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• 2009

지중 양식 중인 메기, Silurus asotus에 Ameiurus nrbulosus 상피종과 유사한 질병이 발생하였다. 상피종은 피부, 지느러미 및 수염에 독립된 형태로 대형의 종괴를 형성하고 있었으며, 조직학적으로는 증생된 상피를 관입된 결합조직에 의해 피포되어 구획되어져 있으며, 증생된 상피 세포는 불규칙한 배열을 하고 있었다. 또한 종양의 내부에는 점액세포와 곤봉세포가 다수 내재되어 있었다. 본 상피종의 발생 원인은 단정할 수는 없지만 상피종을 유발하는 것으로 알려진 바이러스는 검출되지 않았기 때문에 기존에 어류의 종양원으로 보고된 바이러스이외의 종류이던가 아니면 다른 요인이 작용할 것으로 생각되지만 본 연구에서는 원인을 추정할 수 없었다.