• Asian Pacific Journal of Cancer Prevention
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• v.13 no.4
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• pp.1151-1158
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• 2012

High-risk human papillomavirus (HPV) genotypes are the major cause of cervical cancer. Hence, HPV genotype detection is a helpful preventive measure to combat cervical cancer. Recently, several HPV detection methods have been developed, each with different sensitivities and specificities. The objective of this study was to compare HPV high risk genotype detection by an electrochemical DNA chip system, a line probe assay (INNO-LiPA) and sequencing of the L1, E1 regions. A total of 361 cervical smears with different cytological findings were subjected to polymerase chain reaction-sequencing and electrochemical DNA chip assessment. Multiple infections were found in 21.9% (79/361) of the specimens, most prevalently in 20-29-year olds while the highest prevalence of HPV infection was found in the 30-39-year age group. The most prevalent genotype was HPV 16 at 28.2% (138/489) followed by HPV 52 at 9.6% (47/489), with the other types occurring at less than 9.0%. The electrochemical DNA chip results were compared with INNO-LiPA and sequencing (E1 and L1 regions) based on random selection of 273 specimens. The results obtained by the three methods were in agreement except for three cases. Direct sequencing detected only one predominant genotype including low risk HPV genotypes. INNO-LiPA identified multiple infections with various specific genotypes including some unclassified-risk genotypes. The electrochemical DNA chip was highly accurate, suitable for detection of single and multiple infections, allowed rapid detection, was less time-consuming and was easier to perform when compared with the other methods. It is concluded that for clinical and epidemiological studies, all genotyping methods are perfectly suitable and provide comparable results.

• Journal of the Institute of Electronics and Information Engineers
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• v.53 no.9
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• pp.18-25
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• 2016

In D2D communications underlaying a multicell network, it is of primary importance to ensure coexistence of cellular links and D2D links with minimal interference. Therefore, resource allocation scheme for D2D links should be designed to limit the interference between cellular links and D2D links. In this paper, we propose an effective resource allocation scheme for multiple D2D links which share the uplink spectrum resource with cellular users in a multicell network. Under the assumption that the locations of users are known to the base station, the proposed scheme allocates cellular resources to D2D links, such that the interference between a cellular link and multiple D2D links is minimized. In particular, we compute two constants from the path loss model and then use the constants to protect both cellular and D2D links. Simulation results are provided to verify the performance of the proposed scheme.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.34 no.11
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• pp.1715-1720
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• 2010

In this study, we analyzed the crack-healing characteristics of specimens; different crack lengths and coating methods of $Si_3N_4$ ceramic structures with long cracks were analyzed. Cracks with lengths of about $100-500\;{\mu}m$ were obtained using a Vickers indenter for a load of 24.5-98 N. In the case of a crack obtained by applying a load of 24.5 N, the crack-healed specimen with $SiO_2$ nanocolloid coating exhibited the highest bending strength, which was higher than that of a smooth specimen by 140%, but the bending strength of a crack-healed specimen that had a $SiO_2$ nanocolloid coating and originally had multiple cracks was lower than that of a smooth specimen. However, when compared to the cracked specimens, the bending strength of most specimens with multiple cracks increased slightly. On the basis of these results, the crack-healing characteristics of $Si_3N_4$ ceramic structures with multiple indentations were studied for different coating methods. The most effective coating method for long-crack specimens was hydrostatic pressure coating.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.39 no.6
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• pp.779-788
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• 2019

The compaction grouting method is one of the conventional ground improvement methods, which consolidates and compacts the surrounding ground through the injection of grout materials with low mobility. Injecting the grout into the ground can improve the soil properties, as well as form a composite of soil-grout columns. However, the conventional grout pumping is not applicable to handle multiple injection holes at the same time, which may diminish its constructability when the construction time is not enough. This paper proposes a simultaneous multiple compaction-grouting method using a new pump system developed to cover up simultaneously three injection holes at a time. Field injection tests with a single injection hole and with triangular arrangement of injection holes were conducted to evaluate the applicability of the proposed method to soft clay ground. In addition, a series of standard penetration tests (SPTs) were performed to assess the efficiency of each arrangement in improving the soft ground. It is noted from the in-situ test results that the interval distances between injection holes and the elapse time for ground stabilization are the crucial factors governing the applicability of the simultaneous multiple compaction-grouting method to improve the soft clay ground.

• Journal of Science Education
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• v.37 no.1
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• pp.1-10
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• 2013

The purpose of this study was to examine the effect of multiple intelligences-specific observation strategy on observation skills, achievement and scientific attitude in elementary science class For this study, the observation learning for the multiple intelligences-specific observation strategy was applied to elementary science class. The results of this study were as follows: To examine this learning materials were applied to elementary science curriculum, and an experimental group and a control group were selected from 4th graders at elementary school J located in Incheon. The results of this study were as follows.: 1. this study was found statistically significant difference in the pupil's enhancement of the observation ability(p<.05). Specifically, analysis of elements of the observation abilities, it was effective to increase abilities of classification of statements, qualitative observation and quantitative observation. 2. science academic achievement of the group using this developed program was significantly higher compared with a control group. 3. there weren't differences between the comparison and experimental groups in term of the scientific attitude. But the experimental group showed greater increases in the openness, spontaneity and creativity that are the elements of scientific attitude. In conclusion, the Multiple Intelligences Observation Training was useful to develop the elementary school student's the observation ability, science academic achievement, scientific attitude(openness, spontaneity and creativity) and better be widely applied to science education.

• The Journal of Korean Orthopaedic Ultrasound Society
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• v.2 no.2
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• pp.74-78
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• 2009

Purpose: To evaluate the effectiveness of ultrasonography-guided multiple needling for calcific tendinitis of the shoulder. Materials and Methods: We included 18 symptomatic calcific tendinitis patients who underwent ultrasonography-guided multiple needling and followed for average 17 weeks. The procedures were multiple needling or aspiration of the calcific deposit and injection of local anesthetics and steroid into the subacromial bursa under the ultrasound control. Clinical improvements were evaluated using pain VAS, UCLA score and KSS score. The size and status of calcific deposits were compared. Results: A significant improvement was seen in pain VAS, UCLA score and KSS score (p<0.05). At the final follow up, the calcific deposits had resolved completely of nearly completely in 39%, and the size was decreased in 61%. Conclusion: Ultrasound-guided multiple needling is considered as a useful method which could provide prompt pain relief and reduce calcific deposit for calcific tendinitis of the shoulder.

• Journal of Advanced Marine Engineering and Technology
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• v.39 no.7
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• pp.760-764
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• 2015

Wireless sensors, installed on machinery, and Time Division Multiple Access (TDMA) transmission make an ideal system for monitoring machine conditions in industrial plants because there is no need for electronic wiring. However, there has not yet been a successful field application of such a system, capable of continuously transmitting data at sample rates greater than 100 Hz. In this research, a TDMA network protocol capable of acquiring data from multiple sensors at sample rates greater than 100 Hz was developed for field application. The protocol was implemented in a single cluster-star topology network, and the system was evaluated based on the node number and transmission distance. Network simulator 2 (ns-2) was used for a real field simulation. Non-TDMA and TDMA protocol cases were compared using four sensor nodes. In the cases of 20-s and 40-s transmission times, there was little difference between the reception rates of the non-TDMA and TDMA systems. However, the difference was much greater when using a 60-s transmission time.

• The Journal of Korean Orthopaedic Ultrasound Society
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• v.7 no.1
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• pp.13-19
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• 2014

Purpose: To evaluate the effectiveness of ultrasonography-guided combined multiple needling and high-energy extracorporeal shock wave therapy (ESWT) for calcific tendinitis of the shoulder. Materials and Methods: We included 42 calcific tendinitis patients who underwent ultrasonograpy-guided multiple needling followed by high-energy ESWT who visited the clinic from January 2010 to June 2013. The average follow up period was 45 weeks. Clinical evaluation was done before and after 12 weeks from treatment, in clinical terms using pain visual analogue scale (P-VAS), ASES, UCLA scores reflecting performance and symptom improvement, and in sonographic terms by studying the changes in size of the calcific nodules. Results: A statistically significant improvement was seen in P-VAS, ASES, UCLA scores and decreased calcification size on sonographic evaluation. Conclusion: Ultrasonography-guided combined multiple needling and high-energy ESWT is considered as a useful method which could provide clinical function improvement and reduction of calcification deposit.

• Korean Journal of Radiology
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• v.24 no.10
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• pp.1006-1016
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• 2023

Objective: Computed tomography (CT) is an established method for the diagnosis, staging, and treatment of multiple myeloma. Here, we investigated the potential of photon-counting detector computed tomography (PCD-CT) in terms of image quality, diagnostic confidence, and radiation dose compared with energy-integrating detector CT (EID-CT). Materials and Methods: In this prospective study, patients with known multiple myeloma underwent clinically indicated whole-body PCD-CT. The image quality of PCD-CT was assessed qualitatively by three independent radiologists for overall image quality, edge sharpness, image noise, lesion conspicuity, and diagnostic confidence using a 5-point Likert scale (5 = excellent), and quantitatively for signal homogeneity using the coefficient of variation (CV) of Hounsfield Units (HU) values and modulation transfer function (MTF) via the full width at half maximum (FWHM) in the frequency space. The results were compared with those of the current clinical standard EID-CT protocols as controls. Additionally, the radiation dose (CTDIvol) was determined. Results: We enrolled 35 patients with multiple myeloma (mean age 69.8 ± 9.1 years; 18 [51%] males). Qualitative image analysis revealed superior scores (median [interquartile range]) for PCD-CT regarding overall image quality (4.0 [4.0-5.0] vs. 4.0 [3.0-4.0]), edge sharpness (4.0 [4.0-5.0] vs. 4.0 [3.0-4.0]), image noise (4.0 [4.0-4.0] vs. 3.0 [3.0-4.0]), lesion conspicuity (4.0 [4.0-5.0] vs. 4.0 [3.0-4.0]), and diagnostic confidence (4.0 [4.0-5.0] vs. 4.0 [3.0-4.0]) compared with EID-CT (P ≤ 0.004). In quantitative image analyses, PCD-CT compared with EID-CT revealed a substantially lower FWHM (2.89 vs. 25.68 cy/pixel) and a significantly more homogeneous signal (mean CV ± standard deviation [SD], 0.99 ± 0.65 vs. 1.66 ± 0.5; P < 0.001) at a significantly lower radiation dose (mean CTDIvol ± SD, 3.33 ± 0.82 vs. 7.19 ± 3.57 mGy; P < 0.001). Conclusion: Whole-body PCD-CT provides significantly higher subjective and objective image quality at significantly reduced radiation doses than the current clinical standard EID-CT protocols, along with readily available multi-spectral data, facilitating the potential for further advanced post-processing.

• Composites Research
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• v.28 no.6
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• pp.333-339
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• 2015

Electromagnetic interference shielding composite with low density ($1.18g/cm^3$) was fabricated using electroless plated FeCo magnetic metal hollow fibers and ethylene propylene diene monomer (EPDM) polymer. Aspect ratio of the fibers were controlled and their hollow structure was obtained by heat treatment process. The FeCo hollow fibers were then mixed with EPDM to manufacture the composite. The higher aspect ratio of the magnetic metal hollow fibers resulted in high electromagnetic interference shielding effectiveness (30 dB) of the composite due to its low sheet resistance (30 ohm/sq). The enhanced electromagnetic interference shielding effectiveness was mainly attributed to the formation of conducting network over the percolation threshold by high aspect ratio of fibers as well as an increase of the reflection loss by impedance mismatch owing to low sheet resistance, absorption loss, and multiple internal reflections loss.