Background: Chronic obstructive pulmonary disease (COPD) is a serious chronic condition with a global impact. Symptoms of COPD include progressive dyspnea, breathlessness, cough, and sputum production, which have a considerable impact on the lives of patients. In addition to the human cost of living with COPD and the resulting death, COPD entails a huge economic burden on the Chinese population, with patients spending up to one-third of the average family income on COPD management in some regions is clinically beneficial to adopt preventable measures via prudent COPD care utilization, monetary costs, and hospitalizations. Methods: Toward this end, this study compared the relative effectiveness of six indices in predicting patient healthcare utilization, cost of care, and patient health outcome. The six assessment systems evaluated included the three multidimensional Body mass index, Obstruction, Dyspnea, Exercise capacity index, Dyspnea, Obstruction, Smoking, Exacerbation (DOSE) index, and COPD Assessment Test index, or the unidimensional measures that best predict the future of patient healthcare utilization, cost of care, and patient health outcome among Chinese COPD patients. Results: Multiple linear regression models were created for each healthcare utilization, cost, and outcome including a single COPD index and the same group of demographic variables for each of the outcomes. Conclusion: We conclude that the DOSE index facilitates the prediction of patient healthcare utilization, disease expenditure, and negative clinical outcomes. Our study indicates that the DOSE index has a potential role beyond clinical predictions.
Objective: To investigate airway volumes using cone-beam computed tomography (CBCT) by skeletal patterns, sex, and cervical vertebral maturation (CVM) stages in Korean adolescents. Methods: The sample consisted of pretreatment CBCT and cephalograms of 95 adolescents (aged 12-19) obtained out of 1,611 patients examined for orthodontic treatment from 2018 to 2020 in Kyungpook National University Dental Hospital. The samples were classified into two sex groups; three skeletal pattern groups, four chronological age groups and four CVM stages. Nasopharyngeal volumes (NPV), oropharyngeal volumes (OPV), total pharyngeal airway volume (TAV) and minimum cross-sectional area (MCA) measurements were taken from the CBCT. Multiple linear regression analyses to find out which one of the independent variables are good predictors for airway variables. Significant factors were analyzed by two-way multivariate analysis of variance (MANOVA) then multiple comparisons were analyzed using a t-test, and Fisher least significant difference. Results: Age, sex, CVM, and Sella-Nasion-B point have significant influence on airway variable. Males and females showed similar patterns of change in chronological age groups 1-3; however, males had larger NPV, OPV, and MCA at CVM in group 4. According to CVM stages, males had larger OPV, TAV, and MCA at CVM stage 6 (p-value: 0.019, 0.021, 0.015, respectively) and no sex differences at CVM stages 3, 4, and 5. Conclusions: Skeletal patterns have an effect on airway volume. Sex differences were found in CVM 6.
KSCE Journal of Civil and Environmental Engineering Research
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v.5
no.4
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pp.75-86
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1985
A beam with web opening may reduce the cost of steel and the height of multistory steel buildings. Bower's analysis based on the theory of elasticity and Vierendeel analysis had evaluated the normal stresses around the holes, but these analyses have difficulties for practical uses because of complexity and the limitation for their application. In this study, it is shown that the finite element method, using smaller number of isoparametric elements by taking only a part of the beam which includes the hole, can diminish defects of the above two methods and it may represent more satisfactorily the distribution of the local stress concentration around the hole than the other methods which employed linear elements such as in the analysis by Samuel or Redwood. This study presents the effects of moments, shears, and eccentricities of a hole on the distribution of the normal stresses calculated by using the proposed finite element method. Consequently, it is found that the variations of shear force and hole depth give significant effects on the normal stresses around a hole, while the variations of eccentricities of the hole provide a little effect on them. The regression coefficients resulted from the multiple linear regression may be used for estimating the normal stresses around any arbitrary hole in the web of a beam, since the normal stresses guessed by this regression coefficient equation match well the results by the finite element method except the case of large eccentricity.
Han, Yeo-Jung;Han, Mi Ah;Ryu, So Yeon;Choi, Seong Woo
Journal of Korean society of Dental Hygiene
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v.15
no.3
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pp.487-495
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2015
Objectives: The purpose of the study was to investigate the associated factors with oral health behavior in public health majoring students. Methods: Using convenience sampling method, the subjects were 474 health-related majoring students in Jeollanamdo. A self-reported questionnaire was completed from September 1 to 15, 2014. The questionnaire consisted of general characteristics of the subjects, oral health related characteristics, oral health knowledge and behavior. Data were analyzed using SAS 9.3 version. T-test, ANOVA, correlation and multiple linear regression analyses were performed to evaluate the related factors with oral health behavior. Cronbach's ${\alpha}$ in oral health knowledge in this study was 0.52 and that in oral health behavior was 0.80. Results: The overall score of oral health behavior was $3.38{\pm}0.52$. Of all behaviors, the practice in brush of teeth and tongue had the highest mean score. In multiple regression analysis, oral health knowledge in the nursing and dental hygiene students was positively associated with the oral health behavior(${\beta}=0.04$, p=0.003, ${\beta}=0.23$, p=0.003, and ${\beta}=0.18$, p=0.034, respectively). Necessity of dental care, one of oral symptom, and more than two oral symptoms were negatively associated with oral health behavior(${\beta}=-0.14$, p=0.002, ${\beta}=-0.11$, p=0.037, and ${\beta}=-0.17$, p=0.011, respectively). Conclusions: Higher oral health knowledge showed higher levels of oral health behavior. These results will enhance the quality of oral health behavior by increasing the level of oral health knowledge. The optimal oral health education program would be able to improve oral health behavior by increasing the level of oral health knowledge.
Lee, Hyo Jung;Park, Eun-Cheol;Kim, Seung Ju;Lee, Sang Gyu
Asian Pacific Journal of Cancer Prevention
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v.16
no.16
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pp.6913-6917
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2015
Background: Due to the rapid progress of industrialization, the expansion of the nuclear family, and an increase in women's social activities, the burden of care of cancer patients has increased, so that all family members are now involved in care. We compared the health-related quality of life (HRQOL) between members of families of cancer patients (hereafter, cancer families) and members of cancer-free families (non-cancer families). Materials and Methods: The data were from the Community Health Survey (2012). The study population included respondents at least 30 years of age. Data were adjusted for the following covariates: sex, age, education, marital status, household income, economic activity, household type, chronic disease, and perceived health status. Frequency analysis, analyses of variance, and multiple linear regression analysis were performed. Results: Among 163,495 respondents, 3,406 (2.1%) were part of a cancer family and 160,089 (97.9%) were part of a non-cancer family. Cancer families had lower EQ-5D scores than non-cancer families. However, by subgroup, the scores had significant association between cancer and non-cancer families only for females and for those who worked. Conclusions: There was a significant relationship between HRQOL scores and being a family member of a cancer patient. This indicates that the responsibility for care has been extended to the entire family, not only the primary caregiver.
This study evaluated the relative extraction ratio (RER) of As and heavy metals (Cd, Cu and Pb) in paddy soils using the two types extractant, 0.05 M EDTA and 0.43 M HNO3. The RER was calculated by dividing the concentrations of metals obtained by 0.05 M EDTA or 0.43 M HNO3 extraction by those obtained by aqua regia extraction. The RER of 0.43 M HNO3 was larger than that of 0.05 M EDTA. Correlation analysis indicated there was statistically significant correlation (p<0.001) between the concentration in aqua regia and 0.05 M EDTA or 0.43 M HNO3. Especially, Cd showed the higher correlation than other metals. Stepwise multiple linear regression analyses indicated soil pH, CEC, organic matter content, and soil texture all influenced the metal extraction rates and bioavailability of the metals.
Objectives: The purpose of this study was to examine the cross-sectional relationship between low blood lead levels and increasing blood pressure among Korean adults using a nationally representative sample of the Korean population: the Korea National Health and Nutrition Examination Survey (KNHANES) 2008. Methods: A total of 918 subjects aged 40 and older and not currently being treated for hypertension participated in this study. Information about age, gender, smoking status, alcohol consumption, education level, and the use of anti-hypertensive medication was collected. The blood pressure was defined as the mean of the second and the third measurements after three time measurements. Lead levels were determined by an analysis of blood samples. Multiple linear and logistic regression analyses were implemented after adjusting for covariates including age, gender, educational level, smoking status, alcohol consumption, and BMI. Results: This study showed that the average differences in systolic and diastolic blood pressure comparing the lowest to highest quintile of blood lead were 4.33 mmHg (95% CI, 0.66-8.00; p for trend = 0.027) and 2.66 mmHg (95% CI, 0.26-5.06; p for trend = 0.021), respectively. After multivariate adjustment for covariates, the prevalence odds ratio (POR) of subjects in the highest quintile was associated with a 1.70-fold increase in the risks of hypertension (95% CI, 0.83-3.49; p for trend test = 0.112) over those in the lowest quintile of blood lead concentration, However, it was not statistically significant. Conclusions: This study provided evidence for an association between low- levels of blood lead and elevations in blood pressure and risk for hypertension in the general population of Korea.
Kim, Hyo Seong;Son, Ji Hwan;Chung, Jee Hyeok;Kim, Kyung Sik;Choi, Joon;Yang, Jeong Yeol
Archives of Plastic Surgery
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v.47
no.5
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pp.411-418
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2020
Background Excessive bleeding is one of the most severe complications of orthognathic surgery (OGS). This study investigated the associations of intraoperative blood loss and surgical time with the direction of maxillary movement. Methods This retrospective study involved patients who underwent OGS from October 2017 to February 2020. They were classified based on whether maxillary setback was performed into groups A1 and B1, respectively. Relative blood loss (RBL, %) was used as an indicator to compare intraoperative blood loss between the two groups. The surgical time of the two groups was also measured. Subsequently, the patients were reclassified based on whether posterior impaction of the maxilla was performed into groups A2 and B2, respectively. RBL and surgical time were measured in the two groups. Simple linear and multiple regression analyses were performed. P-values <0.05 were considered to indicate statistical significance. Results Eighteen patients were included. The RBL and surgical time for the groups were: A1, 13.15%±5.99% and 194.37±42.04 minutes; B1, 12.41%±1.89% and 196.50±46.07 minutes; A2, 13.94%±3.82% and 201.00±39.70 minutes; and B2, 9.61%±3.27% and 188.84±38.63 minutes, respectively. Only RBL showed a statistically significant difference between the two groups (A2 and B2, P=0.04). Conclusions Unlike maxillary setback, posterior impaction of the maxilla showed a significant association with RBL during surgery. When performing posterior impaction of the maxilla, clinicians need to pay particular attention to surgery and postoperative care.
The beneficial effects of total parenteral nutrition (TPN) in improving the nutritional status of malnourished patients during hospital stays have been well established. However, recent randomized trials and meta-analyses have reported an increased rate of TPN-associated complications and mortality in critically ill patients. The increased risk of complications during TPN therapy has been linked to the development of hyperglycemia, especially during the first few days of TPN therapy. This retrospective study was conducted to determine whether the amount of dextrose from TPN in the 1st week in the intensive care unit (ICU) was related to the development of hyperglycemia and the clinical outcome. We included 88 non-diabetic critically ill patients who stayed in the medical ICU for more than two days. The subjects were 65 ${\pm}$ 16 years old, and the mean APACHE (Acute Physiology and Chronic Health Evaluation) II score upon admission was 20.9${\pm}$7.1. The subjects received 2.3${\pm}$1.4 g/kg/day of dextrose intravenously. We divided the subjects into two groups according to the mean blood glucose (BG) level during the 1st week of ICU stay: <140 mg/dl vs ${\geq}$ 140 mg/dl. Baseline BG and the amount of dextrose delivered via TPN were significantly higher in the hyperglycemia group than those in the normoglycemia group. Mortality was higher in the hyperglycemia group than in the normoglycemia group (42.4% vs 12.8%, P=0.008). The amount of dextrose from TPN was the only significant variable in the multiple linear regression analysis, which included age, APACHE II score, baseline blood glucose concentration and dextrose delivery via TPN as independent variables. We concluded that the amount of dextrose delivered via TPN might be associated with the development of hyperglycemia in critically ill patients without a history of diabetes mellitus. The amount of dextrose in TPN should be decided and adapted carefully to maintain blood glucose within the target range.
Journal of the Korea Academia-Industrial cooperation Society
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v.13
no.6
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pp.2664-2671
/
2012
This study aimed to investigate the relationship between physical characteristics and walking ability in the elderly population. Subjects were 77 elderly (38 men and 39 women) who are capable of walking independently with and without walking aids. Correlation and stepwise multiple linear regression analyses were used to analyze the relationship between physical characteristics (age, gender, height, weight, body mass index, muscle mass, waist/hip ratio, heart rate, vital capacity, flexibility, maximum oxygen consumption, one-leg standing time, and strength of knee flexor and extensor) and walking velocity of subjects. Age, height, vital capacity, one-leg standing time, and strength of knee flexor and extensor showed significant correlations with walking velocity of subjects (p<.05). Further, the strength of knee flexor explained 27% of the variance, and up to 32% of the walking velocity could be explained when the strength of knee extensor were added to the model. The findings suggest that walking velocity of elderly depends on the strength of lower limb's strength and a variety of physical characteristics.
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