• Radiation Oncology Journal
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• 제7권2호
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• pp.235-245
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• 1989

Rhabdomyosarcoma is a highly malignant soft tissue sarcoma that can arise in any site of the body containing striated muscle or its mesenchymal analgae. It is the most common childhood sarcoma with two peak age frequencies, one at ages 2 to 6, and one in the adolescence. The site, stage and extent of disease, and pathologic characteristics of the tumor contribute to prognostic factors that influence therapeutic decisions. The results of treatment of 52 patients with rhabdomyosarcoma, who were treated at Department of Radiation Oncology, Yonsei University College of Medicine, Yosei Cancer Center from 1976 to 1987 were retrospectively analyzed. The most frequent clinical group and primary sites were IRS group III (57.7%) and head and neck (42.3%) including orbit (11.5%) and parameningeal region(13.5%). The overall and disease free 5 year survival rate of eligible 41 patients were 31.7%, 29.3%, respectively. The complete remission (CR) rate was 50% in clinical group III and 0% in IV. Primary tumors of the orbit, clinical group 1 and embryonal subtype had the best prognosis. The Survival rate was improved by additiion of chemotherapy to operation and radiation therapy.

• Radiation Oncology Journal
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• 제7권2호
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• pp.227-233
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• 1989

From April 1986 to Dec 1988, fifty one patients with carcinoma of lung were treated by radiation therapy in Department of Therapeutic Radiology, Yeungnam University Hospital Of the 51 patients, $31(61\%)$ were squamous cell ca, $8(15.7\%)$ were small cell ca, and remained $4(7.9\%)$ were other cell types. Total radiation dose was average $64Gy (60\~75 Gy)$ for group A and 45Gy $(40\~59Gy)$ for group B. The mass regression and the response of airway obstruction to radiation therapy was established on the basis of follow up chest X-ray. The mass regression above $50\%$ of total volume was noted in 23 patients $(74.2\%)$ among 31 patients and the difference between two groups was not seen. In squamous cell ca, however, the mass regression rate (above $50\%$ of total volume) was $83.3\%$ (10/12) in group A compared to $50\%$ (3/6) in group B(p<0.05). The alleviation of airway obstruction was noted as follows. In group A, CR $42.9\%$, PR $35.7\%$, no response $21.4\%$ and in group B, CR $55.6\%,\;PR\;33.3\%$, no response $11.1\%$. But, in squamous cell ca, responsiveness is higher than group B. The study indicates that the importance of higher radiation dose in the management of primary tumor mass and airway obstruction caused by lung cancer especially squamous cell ca. So, meticulous treatment planning and multimodality combination therapy without increasing si.do elect or complication is recommended in management of inoperable bronchogenic carcinoma.

• 대한두경부종양학회지
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• 제21권1호
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• pp.48-52
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• 2005

Objectives: Castleman's disease(CD) is a lymphoproliferative disorder of unknown etiology. To elucidate the clinicopathologic characteristics of CD, we retrospectively reviewed our experience. Methods: Fifteen patients with CD of the neck and mediastinum were identified. Patients were divided into two groups: group I had an unicentric CD and group II had multicentric CD. The histology of CD was divided into 3 subtypes: hyaline-vascular(HV), plasma cell(PC), and mixed. Results: The study included 12 cases of group I, 3 cases of group II in the clinical aspect and 10 cases with HV, 3 cases with PC, 2 cases with mixed type in the histologic aspect. Of group I patients who underwent complete surgical excision, all are currently free of disease. The clinical course of group II patients was variable. Of two patients with multicentric plasma cell CD who were treated, one remain free from disease and the other had a local recurrence in the neck. One patient with multicentric mixed CD died of disease after 30 months of presentation. Conclusion: Surgical resection is recommend for patients with the unicentric CD, regardless of histologic subtype. Patients with multicentric disease do not benefit from surgical resection and should be candidates for multimodality therapy.

• 접착 및 계면
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• 제21권4호
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• pp.162-167
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• 2020

피부 모사형 다기능 유연 센서는 인체 피부의 높은 자극 감지 성능과 기계적 안정성을 모사하고자 다학계적 접근을 통해 발전되어 왔다. 하지만, 실제 적용을 위해서는 일상생활 속에서 접하는 다양한 종류의 자극을 명확히 구분하고 각 자극의 세기를 정확히 감지하는 높은 수준의 자극 구별 능력이 필수적임에도 불구하고, 아직까지 낮은 수준의 자극 구별 능력을 보이는 실정이다. 본고에서는 기존 피부 모사형 유연 센서의 기본적인 작동 메커니즘과 대표적인 연구들을 간략히 소개하고, 최근 보고된 피부 모사형 다기능 유연 센서 관련 연구들의 연구 결과 및 자극 구별 능력에 대해 깊이 있게 다루고자 한다.

• 한국콘텐츠학회논문지
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• 제22권10호
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• pp.213-224
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• 2022

본 연구는 상품과 생산, 마케팅 등 다양한 측면에서 장점을 갖고 있어 급격하게 비중이 커져가는 니트 갑피를 활용한 스니커즈의 스타일 유형과 디자인 특성을 분석하여 디자인 전략과 상품 개발의 방향을 설정하는데 목적이 있다. 이를 위해 니트 갑피 스니커즈 시장에서 주목받고 있는 브랜드의 상품과 온라인 마켓에서 인기를 끌고 있는 상품 총 924개를 대상으로 스타일 유형과 디자인 특성을 분석하였다. 분석된 연구의 결과는 첫째, 고유성으로, 전통적인 소재와 제작기법을 따르지 않음으로써 니트 갑피 스니커즈만의 고유한 하이브리드적 스타일과 디자인이 정립되고 있다. 둘째, 복합성으로 컬러와 소재에 있어 다양한 조합을 통해 각각의 특성을 살린 멀티플한 이미지를 창출하고 있다. 셋째, 실험성으로 일반 스니커즈에 비해 한층 더 공학적이고 새로운 재료와 기법을 접목하여 과감한 디자인 변화를 꾀하고 있다. 스니커즈 시장이 날로 확대되어 가는 현 시점에서 산업의 경향을 반영한 본 연구를 통해 신발 분야에 대한 다양한 연구 활동과 산업 분야의 브랜드 기획 방향에 기초적인 정보를 제공할 것으로 기대한다.

• Journal of information and communication convergence engineering
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• 제20권3호
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• pp.174-180
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• 2022

Emotion recognition is an essential component of complete interaction between human and machine. The issues related to emotion recognition are a result of the different types of emotions expressed in several forms such as visual, sound, and physiological signal. Recent advancements in the field show that combined modalities, such as visual, voice and electroencephalography signals, lead to better result compared to the use of single modalities separately. Previous studies have explored the use of multiple modalities for accurate predictions of emotion; however the number of studies regarding real-time implementation is limited because of the difficulty in simultaneously implementing multiple modalities of emotion recognition. In this study, we proposed an emotion recognition system for real-time emotion recognition implementation. Our model was built with a multithreading block that enables the implementation of each modality using separate threads for continuous synchronization. First, we separately achieved emotion recognition for each modality before enabling the use of the multithreaded system. To verify the correctness of the results, we compared the performance accuracy of unimodal and multimodal emotion recognitions in real-time. The experimental results showed real-time user emotion recognition of the proposed model. In addition, the effectiveness of the multimodalities for emotion recognition was observed. Our multimodal model was able to obtain an accuracy of 80.1% as compared to the unimodality, which obtained accuracies of 70.9, 54.3, and 63.1%.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제17권5호
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• pp.1413-1432
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• 2023

Recommender systems aim to recommend items to users by taking into account their probable interests. This study focuses on creating a model that utilizes multiple sources of information about users and items by employing a multimodality approach. The study addresses the task of how to gather information from different sources (modalities) and transform them into a uniform format, resulting in a multi-modal feature description for users and items. This work also aims to transform and represent the features extracted from different modalities so that the information is in a compatible format for integration and contains important, useful information for the prediction model. To achieve this goal, we propose a novel multi-modal recommendation model, which involves extracting latent features of users and items from a utility matrix using matrix factorization techniques. Various transformation techniques are utilized to extract features from other sources of information such as user reviews, item descriptions, and item categories. We also proposed the use of Principal Component Analysis (PCA) and Feature Selection techniques to reduce the data dimension and extract important features as well as remove noisy features to increase the accuracy of the model. We conducted several different experimental models based on different subsets of modalities on the MovieLens and Amazon sub-category datasets. According to the experimental results, the proposed model significantly enhances the accuracy of recommendations when compared to SVD, which is acknowledged as one of the most effective models for recommender systems. Specifically, the proposed model reduces the RMSE by a range of 4.8% to 21.43% and increases the Precision by a range of 2.07% to 26.49% for the Amazon datasets. Similarly, for the MovieLens dataset, the proposed model reduces the RMSE by 45.61% and increases the Precision by 14.06%. Additionally, the experimental results on both datasets demonstrate that combining information from multiple modalities in the proposed model leads to superior outcomes compared to relying on a single type of information.

• 대한영상의학회지
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• 제83권1호
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• pp.230-238
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• 2022

폴리아크릴 아마이드겔(polyacrylamide gel; 이하 PAAG)은 중국, 동유럽 등에서 유방 확대술에 이용되던 물질이었으나, 다양한 부작용을 일으키는 것으로 밝혀져 현재는 사용이 금지된 물질이다. 그러나 위에서 언급된 국가의 여성들이 다른 국가로 이주하게 되면서, 우리나라에서도 PAAG를 이용한 유방 확대술을 시행한 환자들을 만나게 되었다. 이를 시행한 경우, 매우 다양한 영상의학적 소견을 보이며, 이로 인해 악성 종양이나 다른 진단과의 감별이 어렵기 때문에 정확한 진단 및 치료 계획을 세우기 위해 다양한 영상의학적 소견에 대해 숙지하는 것이 필요하다. 현재까지 한국에서의 PAAG 유방 확대술에 의한 부작용과 관련된 영상의학적 소견에 대해 보고된 바가 적기 때문에, 이에 PAAG 유방 확대술을 시행한 네 개의 증례 통해 다양한 영상의학적 진단 도구를 통한 영상의학적 소견에 대하여 보고하고자 한다.

• Journal of Korean Neurosurgical Society
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• 제44권4호
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• pp.222-227
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• 2008

Objective : Malignant gliomas are the most common primary cerebral neoplasms in adults. Despite multimodality treatments, the prognosis for patients with malignant glioma remains poor. However, recently, the effectiveness of concomitant chemoradiotherapy (CCRT) with temozolomide (TMZ) has been reported. We report for the first time preliminary results of the treatment with CCRT of newly diagnosed malignant gliomas in Korean people. Methods : Thirty-two patients over the age of 17 years with newly diagnosed and histologically confirmed high-grade gliomas (HGG), from June 2004 to August 2007 were the subjects of this study. There were 17 men and 15 women, with a median age of 53.5 years (range, 17-74). Pathologically, glioblastoma, anaplastic astrocytoma, anaplastic oligodendroglioma, and gliomatosis cerebri had been diagnosed in eighteen, eight, four, and two patients, respectively. These 32 patients were treated with CCRT with TMZ. Results : The median follow-up period was 12.5 months (range 3-48). At the time of this analysis, 13 patients died and three patients had been lost to follow-up. There was no mortality caused by drug toxicity. The median progression-free survival (PFS) of these patients was 9.0 months, and the six-month PFS rate was 72.4%. The median overall survival (OS) was 26 months, and the one-year OS rate was 83.6%. The 18 patients with glioblastoma were analyzed separately from the other patients with HGG, and the median OS was 18 months, and the one-year OS rates were 81.8%. The median PFS was seven months, and the six-month PFS rate was 75.0%. Conclusion : Our results are consistent with many other reports, confirming that CCRT with TMZ achieves good clinical outcomes in the treatment of HGG. Therefore, we suggest that CCRT with TMZ as adjuvant chemotherapy be considered as a standard therapy for patients with HGG.

• Radiation Oncology Journal
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• 제12권3호
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• pp.307-313
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• 1994

Purpose : Maxillary sinus cancers usually are locally advanced and involve the structures around sinus. It is uncommon for this cancer to spread to the regional lymph-nodes. For this reason, local control is of paramount important for cure. A policy of combined treatment is generally accepted as the most effective means of enhancing cure rartes. This paper reports our experience of a retrospective study of 31 Patients treated with radiation therapy alone and combination therapy of surgery and radiation. Materials and Methods: Between July 1974 and January 1992, 47 Patients with maxillary sinus cancers underwent either radiation therpay alone or combination therapy of surgery and radiation. Of these, only 31 patients were eligible for analysis. The distribution of clinical stage by the AJCC system was $26\%$(8/31) for T2 and $74\%$(23/31) for T3 and T4. Eight patients had palpable lymphadenopathy at diagnosis. Primary site was treated by Cobalt-60 radiation therapy using through a $45^{\circ}$ wedge-pair technique. Elective neck irradiation was not routinely given. Of these 8 patients, the six who had clinically involved nodes were treated with definite radiation therapy. The other two patients had received radical neck dissection. The twenty-two patients were treated with radiation alone and 9 patients were treated with combination radiation therapy, The RT alone patients with RT dose less than 60 Gy were 9 and those above 60 Gy were 13. Results : The overall 5 year survival rate was $23.8\%$. The 5 year survival rate by T-stage was $60.5\%$ and $7.9\%$ for T2 and T3,4, respectively. Statistical significance was found by T-stage(p<0.005). The 5 year survival rate by N-stage was $30\%$ for N (-) and $8.3\%$ for N(+), but statistically no significant difference was seen(p${\geq}$0.1). The 5 year survival rate for RT alone and combination RT was $22.5\%$ and $27.4\%$, respectively. The primary local control rate was $65\%$ (20/31). Conclusion : This study did not show significant difference in survival between RT alone and combination RT. There is still much controversy with regard to which treatment is optimum. Improved RT technique and development of multimodality treatment are essential to improve the local control and the survival rate in patients with advanced maxillary sinus cancer.