• The Journal of Internal Korean Medicine
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• 제45권1호
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• pp.1-10
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• 2024

Objectives: This study investigated the pattern identification (PI) and clinical index of Parkinson's disease (PD) for personalized diagnosis and treatment. Methods: This prospective observational multi-center study recruited 100 patients diagnosed with PD from two Korean medicine hospitals. To cluster new subtypes of PD, items on a PI questionnaire (heat and cold, deficiency and excess, visceral PI) were evaluated along with pulse and tongue analysis. Gait analysis was performed and blood and feces molecular signature changes were assessed to explore biomarkers for new subtypes. In addition, unified PD rating scale II and III scores and the European quality of life 5-dimension questionnaire were assessed. Results: The clinical index obtained in this study analyzed the frequency statistics and hierarchical clustering analysis to classify new subtypes based on PI. Moreover, the biomarkers and current status of herbal medicine treatment were analyzed using the new subtypes. The results provide comprehensive data to investigate new subtypes and subtype-based biomarkers for the personalized diagnosis and treatment of PD patients. Ethical approval was obtained from the medical ethics committees of the two Korean medicine hospitals. All amendments to the research protocol were submitted and approved. Conclusions: An objective and standardized diagnostic tool is needed for the personalized treatment of PD by traditional Korean medicine. Therefore, we developed a clinical index as the basis for the PI clinical evaluation of PD. Trial Registration: This trial is registered with the Clinical Research Information Service (CRIS) (KCT0008677)

• Journal of Korea Spatial Information System Society
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• 제8권2호
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• pp.13-38
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• 2006

Range query is one of the most important operations for spatial objects, it retrieves all spatial objects that overlap a given query region in multi-dimensional space. The DOT(DOuble Transformation) is known as an efficient indexing methods, it transforms the MBR of a spatial object into a single numeric value using a space filling curve, and stores the value in a $B^+$-tree. The DOT index is possible to be employed as a primary index for spatial objects. However, the range query processing based on the DOT index requires much overhead for spatial transformations to get the query region in the final space. Also, the detailed range query processing method for 2-dimensional spatial objects has not been studied yet in this paper, we propose an efficient multi-dimensional range query processing technique based on the DOT index. The proposed technique exploits the regularities in the moving patterns of space filling curves to divide a query region into a set of maximal sub-legions within which space filling curves traverse without interruption. Such division reduces the number of spatial transformations required to perform the range query and thus improves the performance of range query processing. A visual simulator is developed to show the evaluation method and the performance of our technique.

• Korean Journal of Ecology and Environment
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• 제56권1호
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• pp.70-82
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• 2023

Recently, Korean government has introduced Multi Metric Indices (MMI) using various biocommunity information for aquatic ecosystem monitoring and ecosystem health assessment at the national level. MMI is a key tool in national ecosystem health assessment programs. The MMI consists of indices that respond to different target environmental factors, including environmental disturbance (e.g. nutrients, hydrological and hydraulic situation of site etc.). We used zooplankton community information collected from Korean lakes to estimate the availability of candidate zooplankton MMI indices that can be used to assess lake ecosystem health. First, we modified the candidate indices proposed by the U.S. EPA to suit Korean conditions. The modified indices were subjected to individual index suitability analysis, correlation analysis with environmental variables, and redundancy analysis among indices, and 19 indices were finally selected. Taxonomic diversity was suggested to be an important indicator for all three taxonomic groups (cladoceran, copepod, rotifer), on the other hand, the indices using biomass for large cladocerans and copepods, while the indices using abundance were suggested for small cladocerans and rotifers.

• Korean Journal of Optics and Photonics
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• 제16권6호
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• pp.527-534
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• 2005

We investigate the pulsation characteristics in a multi-section DFB laser which is composed of one DFB section, phase tuning section, and gain section. Multi-section DFB lasers with anti-phase (AP) complex-coupled (CC) DFB structure show wide current ranges of gain and phase tuning sections fer stable pulsations compared to those with in-phase CC DFB structure or index-coupled DFB structure. For multi-section DFB lasers with AP CC DFB structure, the current range of a gain section for stable pulsations increases and the tuning range of the pulsation frequency increases as a coupling strength or a gain coupling coefficient increases Also, the tuning range using the phase variation in a phase tuning section increases. For a fixed coupling strength, the current ranges of gain and phase tuning sections for stable pulsations increase and the tuning range of the pulsation frequency increases as the length of a DFB section increases.

• Journal of the Korea Academia-Industrial cooperation Society
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• 제16권5호
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• pp.3579-3586
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• 2015

In this study, EEG, HRV, and Vibra image were compared and analyzed in the environmental test room due to stimulation of aroma and color temperature. The condition of the environmental test room was in temperature $25[^{\circ}C]$, relative humidity 50[RH%], air current speed 0.02[m/s] and illuminance 1000[lux] with setting up different sensory stimulation condition which are before exposure, single-sensory stimulation of Jasmine scent, single-sensory stimulation of RED color lighting, and multi-sensory stimulation of Jasmine scent and RED color lighting. The result of this study, at multi-sensory stimulation of Jasmine scent and RED color lighting, relative $S{\alpha}$ wave, SEF50, $SMR/{\theta}$ and SDNN were revitalized, and both sides ${\alpha}$ wave asymmetry index, stress index, fatigue degree, and HRT were decreased. Also, Viba image of tension/anxiety and stress were declined. Therefore multi-sensory stimulation of Jasmine scent and RED color lighting effects to increase the Neuro-energy like amenity, productivity of work efficiency, and concentration.

• Journal of Advanced Marine Engineering and Technology
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• 제37권5호
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• pp.500-509
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• 2013

This study reports a numerical analysis of the internal flow characteristics of the integrated urea-SCR muffler system with the various geometries of the multi-perforated tube which is set up between the muffler inlet and in front of SCR catalysts. The multi-perforated tube is generally used to disperse uniformly the urea-water solution spray and to make better use of the SCR catalyst, resulting in the increased $NO_x$ reduction and decreased ammonia slip. The effects of the multi-perforated tube orifice area ratios on the velocity distributions in front of the SCR catalyst, which is ultimately quantified as the uniformity index, were investigated for the optimal muffler system design. The steady flow model was applied by using a general-purpose commercial software package. The air at the room temperature was used as a working fluid, instead of the exhaust gas and urea-water solution spray mixture. From the analysis results, it was clarified that the multi-perforated tube geometry sensitively affected to the formation of the bulk swirling motion inside the plenum chamber set in front of the SCR catalyst and to the uniformity index of the velocity distribution produced at the inlet of the catalyst.

• Journal of the Korean Society of Safety
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• 제24권2호
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• pp.76-82
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• 2009

The NIOSH lifting equation has been used as a dominant tool in evaluating the hazard levels of lifting tasks. Although it provides two different ways for each simple and complex lifting task, the NIOSH simple lifting equation is almost used for not only simple tasks but also complex tasks. However, most of lifting tasks in industries are in the form of complex lifting. Therefore some errors occur inevitably in the evaluation of complex lifting tasks. Among complex lifting tasks, a multi-stacking task is the most popular in lifting tasks. To compensate the error in the evaluation of multi-stacking tasks by using the NIOSH simple lifting equation, a set of calculations for finding LIs(Lifting Indices) was performed for the systematically varying multi-stacking tasks. Then a regression model which finds the equivalent height in simple lifting task for multi-stacking task was established. By using this model, multi-stacking tasks can be evaluated with less error. To validate this model, some real multi-stacking tasks were evaluated as examples.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제9권7호
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• pp.2599-2613
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• 2015

Multi-index hashing (MIH) is the state-of-the-art method for indexing binary codes, as it di-vides long codes into substrings and builds multiple hash tables. However, MIH is based on the dataset codes uniform distribution assumption, and will lose efficiency in dealing with non-uniformly distributed codes. Besides, there are lots of results sharing the same Hamming distance to a query, which makes the distance measure ambiguous. In this paper, we propose a data-oriented multi-index hashing method (DOMIH). We first compute the covariance ma-trix of bits and learn adaptive projection vector for each binary substring. Instead of using substrings as direct indices into hash tables, we project them with corresponding projection vectors to generate new indices. With adaptive projection, the indices in each hash table are near uniformly distributed. Then with covariance matrix, we propose a ranking method for the binary codes. By assigning different bit-level weights to different bits, the returned bina-ry codes are ranked at a finer-grained binary code level. Experiments conducted on reference large scale datasets show that compared to MIH the time performance of DOMIH can be improved by 36.9%-87.4%, and the search accuracy can be improved by 22.2%. To pinpoint the potential of DOMIH, we further use near-duplicate image retrieval as examples to show the applications and the good performance of our method.

• Journal of radiological science and technology
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• 제27권2호
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• pp.21-27
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• 2004

This study was conducted to estimate absorbed radiation doses associated with CT examinations. We compared CT dose index between single detector CT and multi detector CT. To establish radiation dose criteria in CT examination in Korea, we measured radiation dose for CT examinations in Seoul and kyungki-do. The results obtained were as follows ; 1. Averaged CTDIW value per 100 mAs was $13.5{\pm}3.2\;mGy$, and ranged from 8.1 mGy to 19.1 mGy in head phantom, was $7.1{\pm}2.0\;mGy$, and ranged from 3.7 mGy to 10.9 mGy in body phantom. 2. CTDIW was 3.2 mGy(1.26 times) larger in multi detector CT than single detector CT in head phantom, and 2.1 mGy(1.34 times) larger in body phantom. 3. The dose was the highest in 4 channel multi detector CT, and followed 8 channel multi detector CT, 16 channel multi detector CT and single detector CT in head phantom. And the dose was the highest in 4 channel and 8 channel multi detector CT, and followed 16 channel multi detector CT and single detector CT in body phantom.

• Journal of Korean Institute of Industrial Engineers
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• 제10권2호
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• pp.29-36
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• 1984

This paper proposes a procedure for solving a multi-stage stockpile problem with budget constant. To establish the stockpile importance index, value assessment procedure is employed with two attributes; item's essentiality and Unsatisfactoriness rate of requirements, Then we propose the balancing of stockpile importance index among stockpile items as a reasonable objective for stockpile problem.