• Title/Summary/Keyword: mucosa

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Salivary Components Adsorbing to Oral Mucosal Epithelial Cells (구강점막 상피세포에 부착하는 타액 성분)

  • Kho, Hong-Seop
    • Journal of Oral Medicine and Pain
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    • v.24 no.3
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    • pp.261-267
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    • 1999
  • The present investigation was carried out to identify salivary components of mucosal pellicle and to explore the difference of mucosal pellicle components according to the location of oral mucosa. By using antisera and immunoblotting, high-(MG1) and low-(MG2) molecular-mass salivary mucins, amylase, IgA, proline-rich proteins(PRPs) were detected in mucosal pellicle in vivo. In addition, the data indicated that mucins, IgA and proline-rich proteins could be cleaved into lower-molecular-mass products, whereas the IgA, proline-rich proteins could also be cross-linked into higher-molecular-mass complexes. Mucosal pellicles from buccal, labial and palatal mucosa showed similar pattern in immunoblotting experiments using anti-MG2 and anti-PRPs antisera. The data from this study suggest that during mucosal pellicle formation multiple components of saliva adsorb to oral mucosal epithelial cell surfaces, and selected components can be proteolytically cleaved into smaller fragments and/or cross-linked into higher-molecular products.

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Melanosis Coli Associated with Aloe Consumption in a Child (알로에 복용 후 발생한 소아 대장 흑색증 1예)

  • Shim, Jeong-Ok;Lee, Seung-Koo
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.13 no.1
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    • pp.81-85
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    • 2010
  • Melanosis coli is described as a black or brown discoloration of the mucosa of the colon. Such a discoloration is largely due to pigment granule deposition in macrophages in the colonic mucosa, which arises from anthraquinone-containing laxative abuse. Melanosis coli has usually been reported in the elderly. We present the first case of melanosis coli associated with aloe consumption in a Korean child.

Histochemical Properties Study on the Mucosubstances of the Intestinal Mucosa in the Raja kenojei (홍어 장점막 점액의 조직화학적 성상에 관한 연구)

  • Joo, Kyeng Woong
    • Korean Journal of Clinical Laboratory Science
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    • v.36 no.2
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    • pp.173-177
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    • 2004
  • This study is performed in order to clarify the histochemical structure, the distribution of mucous cell and goblet cell, and the histochemical properties of the mucosubstances in the middle region of intestinal mucosa and rectum of Raja kenojei. In the H&E stain, distribution of the mucous cells and acidophilic cells were a more compacted middle portion than other regions of intestine, but the former was more than the latter in the number of mucous cells to rectum. The mucosubstances were stained with aldehyde fuchsin pH 1.7-alcian blue(pH 2.5) stain and then compared to distribution of the mucosubstances used in image and microscope technology(IMT-Size5). The middle intestine of Raja kenojei was composed of mucous cells having only large amounts of mucosubstances in the distal region was much more than that of proximal region. It was two types of mucous cells to rectum, one type was the same as proximal intestine while the other had small amounts of weakly sulfated and large amounts of carboxylated mucins.

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AN EXPERIMENTAL STUDY ON SKIN AND MUCOSAL GRAFTS IN THE ORAL CAVITY (구강내 피부 및 점막이식에 관한 실험적 연구)

  • Choi, Jae-In;Kim, Jong-Won
    • The Journal of the Korean dental association
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    • v.22 no.1 s.176
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    • pp.49-55
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    • 1984
  • The objective of this study was to observe the healing of skin and mucosal grafts, comparing with the control sites. Six adult dogs were divided into two groups of three. Mucosal defects were created in all four quadrants, and the left side was used as a control. In the Group I animals, a split-thickness skin from the chest was grafted, and in the group II animals, a split-thickness mucosa from the buccal cheek was grafted into the mouth. Gross and microscopic examination was done at 3, 7, 14, 28, 42 days. The results were as follows. 1. Wound epithelization was accelerated in the supraperiosteal grafts. 2. After healing, the grafted skin was unnatural to the oral cavity, showing grayish-white color, hair, and sebaceous gland. But the mucosal grafts could not be discriminated from the adjacent mucosa. 3. the grafting on the cortical bone failed.

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A Case of Pyogenic Granuloma of Vocal Cords (성대에 발생한 화농성 육아종 1예)

  • 박경호;유영화;김수환;조승호
    • Korean Journal of Bronchoesophagology
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    • v.9 no.2
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    • pp.74-77
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    • 2003
  • Pyogenic granuloma is very uncommon disease. It is a benign, elevated, and capillary-rich lesion occupying on the skin and mucous membranes, and is a reactive lesion, an overgrowth of granulation tissue. And this lesion may grow rapidly and can recur frequently. Pyogenic granuloma usually occurs on the lip, tongue, oral mucosa, and nasal mucosa. But, pyogenic granuloma of vocal cords is very rare. Recently, we experienced a case of pyogenic granuloma of a 48-year-old man who had been presented with hoarseness for 3 months. He was diagnosed pyogenic granuloma after laryngeal microscopic surgery. So we report this rare case with review of literatures.

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Effect of Sodium Taurodihydrofusidate on Nasal Drug Delivery: Differences in Its Concentration and Penetrant Molecular Weight

  • Hosoya, Ken-ichi;Kubo, Hiroyuki;Takashi-Akutsu;Hideshi-Natsume;Kenji-Sugibayashi;Yasunori-Morimoto
    • Archives of Pharmacal Research
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    • v.17 no.2
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    • pp.57-59
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    • 1994
  • The effect of sodium taurodihydrofusidate (STDHF) on drug permeation across nasal mucosa was studied in vitro using Ussing type diffusion chamber. Disodium cromoglicate (DSCG, M.W.5123) and fluorescein isothiocyanate-dextran (FD) of different molecular wieghts (M.W. 4400-71200) were used as model drugs. Pemeation profiles of DSCG and FDs showed a typical pseudo steady-state curve with short lag time. The pemeability coefficient of FD (M.W. 9400) sigmodially increased with increasing STDHF concentration. It also enhanced the DSCG pemeation. Interestingly the enhancement efficacy was independent of molecular weight of penetrants.

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PATHOLOGIC STUDIES ON SODIUM MONOFLUOROACETATE (COMPOUND 1080) POISONING IN RABBITS (Sodium monofluoroacetate (Compound 1080) 중독(中毒)에 관(關)한 가토(家兎)의 병리해부학적(病理解剖學的) 연구(硏究))

  • Kim, Hwa Sik
    • Korean Journal of Veterinary Research
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    • v.1 no.1
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    • pp.65-70
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    • 1961
  • Many losses in domestic animals have bern reported in this country, since sodium monofluoroacetate (Compound 1080) was used as a rodenticide. Lesions described inclubed multiple petechiae in epi- and endocardium, lung and intestinal mucosa, or superficial necrosis of the gastric mucosa. In this studies as to the poisoning 7 rabbits were administered 0.6mg (Group I), 0.4mg (Group II), and 0.3mg (Group III) of sodium monofluoroacetate per kilogram of body weight. and the results obtained were as follows: In addition to the changes mentioned above fatty degeneration in central parts of hepatic lobule or nut meg liver, haemorrhagic feci in cerebral cortex and leptomeninges and fatty degeneration in kidney and cardiac muscles were found.

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An embouchure aid for saxophone player (색소폰 연주자를 위한 앙부슈어 보조 도구의 제작)

  • Moon, Ho-Jin
    • Restorative Dentistry and Endodontics
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    • v.37 no.1
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    • pp.54-60
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    • 2012
  • This study aims to introduce the method that can relieve vibrating forces to oral environment by making an embouchure aid. Thin plastic crown forms were fabricated to prevent tooth abrasion and irritation to lip mucosa for the saxophone player. After application to the player, the most comfort form was chosen and delivered to 3 professional saxophone players. After 5 mon, the players responded to the survey. This embouchure aid did not disturb playing and gave comfort to lower lip. In general, the players preferred thin soft type and thought it caused little effect on sound. Far too little attention has been paid to the problems encountered by single-reed wind instrumentalist who suffer from tooth abrasion and irritation to lip mucosa. The embouchure aid not only prevent tooth damage but also diminish the discomfort of tight embouchure.

Ultrasonography in periodontal diagnosis (악안면 초음파의 치주학적 활용)

  • Kim, Dae-Yeob;Lee, Jong-Bin;Pang, Eun-Kyoung
    • The Journal of the Korean dental association
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    • v.55 no.11
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    • pp.800-807
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    • 2017
  • Ultrasonography is one of the most common diagnostic tools in medical imaging with non-invasive and non-radiation loaded characteristics. In the field of dentistry, especially for periodontology, high frequency ultrasonic device can be used for several purposes such as evaluating gingival thickness, identifying the level of alveolar bone, measuring the volume of mucosa of donor site for soft tissue graft and so on. According to recent studies, it was demonstrated that ultrasonic diagnosis had both accuracy and repeatability comparable to conventional diagnostic tools. However, improvement and development of intra-oral probe suitable for adpatation to gingiva and palatal mucosa, are considered as prerequisites for diffusion of ultrasonic diagnosis in periodontology.

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HUGE PERIPHERAL OSSIFYING FIBROMA OF THE LOWER POSTERIOR EDENTULOUS RIDGE : CASE REPORT

  • Kim, Jae-Jin;Kim, Eun-Seok
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.31 no.5
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    • pp.435-439
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    • 2009
  • The peripheral ossifying fibroma(POF) is a relatively common, non-neoplastic gingival growth that is classified as a reactive hyperplastic inflammatory lesion. The clinical appearance of POF is generally a small, well-circumscribed, focal mass with a sessile or pedunculated base. The pathogenesis of this lesion is uncertain. POFs are believed to arise from cells of the periodontal ligament as hyperplastic growth of tissue that is unique to the gingival mucosa. Approximately 60% of POFs occur in the maxilla, and 55%-60% of all cases occur in the incisor-canine area. Most lesions are less than 2 cm in size. To our knowledge, huge POF of approximately 8 cm in size in the lower posterior edentulous ridge has not been previously described in the English literature. We report an unusually huge POF overlying the lower posterior edentulous ridge mucosa, along with long-term follow up result.