• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.26 no.1
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• pp.19-34
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• 2013

Objective : This study was performed to evaluate the effect of immune reaction inductive substances such as PMA, LPS, DPE, DNCB and WP, the whitman pigra extracting substance at simultaneously on the translocation of $NF{\kappa}B$ towards to the nucleus and the mRNA expression patterns of various cytokine genes in THP-1 cells, monocytes of human. Methods : To analyze the cytokine genes expressions, the RT-PCR method was used, and measuring TNF-${\alpha}$ that had been secreted during cell culture by the ELISA method. The morphological changes were observed during THP-1 cell by a scanning electron microscope and the quantitative distribution of $NF{\kappa}B$ in the cell that was analyzed through immunocytochemistry and a confocal microscopy. Results : WP showed different influences onto the mRNA expression patterns of cytokine genes with PMA, LPS. DPE and DNCB according to the types of immune inductive substances in the THP-1 cells. Upon treating PMA and DPE on the THP-1 cells at the same time or either additionally treating WP thereon, the movement of $NF{\kappa}B$ increase towards the nucleus from cell cytoplasm was able to be observed. The expressions of IL-$1{\alpha}$ and IFN-${\gamma}$ induced by PMA and PMA+DNCB were suppressed by WP while the expression of TGF-${\beta}$ was promoted. Regarding the secretion pattern of TNF-${\alpha}$ according to the treatment of PMA, its secretion amount was incredibly increased by concurrent treatment of WP, however, in case of co-treatment of WP with PMA and DNCB, it was found that the secretion amount of TNF-${\alpha}$ decreased. Conclusions : In this study, the WP extracting substance was confirmed that it had an influence on expression patterns of cytokine genes according to the actions of a variety kinds of immune reaction inductive substances treated on the THP-1 cells. Especially, WP co-treatment with PMA and DNCB was suppressed the expression of inflammatory cytokines, such as IL-$1{\alpha}$, IFN-${\gamma}$ and TNF-${\alpha}$.

• PNF and Movement
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• v.14 no.3
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• pp.237-244
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• 2016

Purpose: This case report examines the influence of proprioceptive neuromuscular facilitation (PNF) combined with a dynamic neuromuscular stabilization approach on balance in patients with cerebellar atrophy. Methods: The target subject of this case report was a 34-year-old woman who was informed of the purpose of this research and voluntarily agreed to participate in it. The case report conformed to research ethics based on the Helsinki Declaration. The target subject was confirmed to have cerebellar atrophy from an unknown cause in 2009 and was diagnosed with slight ataxia. At that time, she could carry out daily activities without physical therapy. On May 19, 2015, she suffered both a subdural hemorrhage (SDH) and subarachnoid hemorrhage (SAH) in a traffic accident. She was urgently moved to the emergency room and managed by nonsurgical treatment, and then, the cerebellar atrophy and ataxia gradually deteriorated. To evaluate the patient's balance capacity before and after intervention, the trunk impairment scale (TIS), trunk impairment scale (OLST) during eye-closing/opening, timed up and go test (TUG), and visual analogue scale (VAS) were conducted. The PNF intervention program was executed for 30 min, four times a week, for three weeks. Results: The TIS and OLST during eye-closing/opening were improved by as much as a point, by 8.15 s and 6.21 s, respectively, after applying the PNF program. TUG and VAS decreased by 1.33 s and 3 points, respectively, after intervention. According to the result, the OLST during eye-closing/opening and VAS improved remarkably in comparison with those before intervention. Conclusion: As the final result of the case report, PNF intervention combined with DNSA more effectively improved the static balance capacity, such as the OLST during eye-closing/opening and VAS, compared to the dynamic balance capacity. In addition, the intervention duration and period of the exercise program are recommended to be more than 1 h a day for four weeks considering the learning ability of a patient with cerebellar atrophy.

• Korean Journal of Digital Imaging in Medicine
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• v.9 no.2
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• pp.31-38
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• 2007

To evaluate the accuracy and extent in the localization of cerebral motor coutex activation using a gradient- echo echo planar imaging(GE-EPI) compared to spin-echo echo planar iimaging(SE-EPI) on 3T MR imaging. Functional MR imaging of cerebral motor cortex activation was examined in GE-EPI and SE-EPI in five healthy male volunteers. A right finger movement was accomplished with a paradigm of 6 task and rest, periods and the cross-correlation was used for a statistical mapping algorithm. We evaluated any sorts of differenced of the time seried and the signal intensity changes between the rest and task periods obtained with two technoques. The qualitative analysis was distributed with activation sites of large veins and small veins by using two techniques and was found that both the techniques were clinically uesful for delineating large veins and small veins in fMRL Signal intensity charge of the rest and activation periods provided simmilar activations in both methods(GE-EPI : 0.93$\pm$0.11, SE-EPI : 0.80$\pm$.015) but the signal intensity in GE-EPI(133.95$\pm$15.76) was larger than in SE-EPI(74.5$\pm$18.90). The average SNRs of EPI raw data were higher at SMA in SE-EPI(48.54$\pm$12.37) than GE-EPI(41.4$\pm$12.54) and at M1 in SE-EPI(43.24$\pm$11.77) than GE-EPI(38.27$\pm$6.53). The localization of activation voxels of the GE-EPI showed a larger vein but the SE-EPI generally showed small vein. Then the analysis results of the two techniques were used for a statistacal paired student t-test. SE-EPI was found clinically useful for localizing the cerebral moter cortex cativation on 3.0T, but showed a little different activation patterns comparad to GE-EPI. In conclusion, SE-EPI may be feasible and can detect true cortical activation from capillaries and GE-EPI can obtain the large veins in the motor cortex activation on 3T MR imaging.

• Journal of Hospice and Palliative Care
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• v.17 no.4
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• pp.270-277
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• 2014

Purpose: This is a retrospective study that investigated cancer patients' complaints of moderate or severe pain to analyze pain characteristics, pain relief interventions and their effects. Methods: The participants of this study were 363 patients who were hospitalized in the cancer ward for three to 30 days and scored 4 points or higher on the pain severity assessment. Results: The most frequent region of pain was the abdomen. The most frequent factor that exacerbated pain was movement. The most frequent pain alleviating factor was administration of analgesics. The most frequent pain type was breakthrough pain, and the most frequent non-pharmaceutical intervention for pain control was heat therapy. Among all, analgesics were routinely prescribed for 52.2% of the participants. Morphine sulfate was the most frequently used analgesic while Gabapentin was the most frequently used non-narcotic analgesic. At the time of discharge, 82.5% of the participants marked their pain intensity as 3 points or lower. Conclusion: For cancer patients complaining of moderate or severe pain, it is important to actively control pain from the beginning of admission. Thus, it is necessary to educate not only cancer patients using narcotic analgesic for pain control and their families but nurses about the effects and side-effects of drugs. Moreover, patients and their families need to learn how to assess and record pain at home to collect data that can be referred for future treatment.

• Journal of the Korean Society for Nondestructive Testing
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• v.23 no.1
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• pp.30-37
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• 2003

In order to replace the manual ultrasonic testing(UT) with an automated UT(AUT), a scanner which enables us to control the positions of a transducer is essential. Encoders have been commonly used to obtain the position information from the conventional scanners controlled by motor. Encoders have various advantages in many aspects. However, if the slip of motor wheel occurs during scanning, various errors are involved in the position accuracy. Thus, the position information of encoders becomes meaningless in case of slip. The reliability of AUT results nay become serious problem. Hence, slip must be avoided, but it can not be completely avoided at present time. In this paper, a new idea that surface wave is used to solve this problem and replace encoders has been proposed. It is shown that this idea can be employed in AUT scanner without encoders. That is, one transducer transmitting surface wave is fixed and the other transducer attached to the scanner receives UT signal. Then, computer calculates the present position of scanner based on the information given by surface wave. Thus, the movement of a scanner can be controlled by the amount of input based on the information obtained.

• The Journal of Internal Korean Medicine
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• v.21 no.1
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• pp.169-180
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• 2000

Objectives : To satisfy the demand of good treatment of constipation Methods : we investigated the literatures of Oriental Medicine about Constipation. Results: 1. There are three categories of etimological factors of constipation, that is, endogenous, exogenous and non-exo-endogenous factor. The endogenous factor is caused by seven emotions, called depression of Ki and stagnation of Ki. The exogenous factor is six excessive atmospheric influences, for example, wind, cold, dampness, heat and dryness. And the non-exo-endogenous factors are overfatigue, improper diet, stagnated blood and deficiency of Ki and blood that comes from old age, long disease and after delivery. 2. Classification: According to cause of disease it is classified by constipation due to cold, heat, wind, dryness, retention of undigested and phlegm. According to Internal Organs there are constipation due to deficiency syndrome of the stomach, excess syndrome of the stomach, deficiency syndrome of kidney and splenic constipation. And Differentiation of syndromes according to Ki and blood, there are constipation of deficiency type and excess type. There are constipation due to stagnation and deficiency of Ki, deficiency of blood and stagnated blood. 3. Principles and Methods of treatment 1) Herbal Medicine (1) Excess type [1] Constipation due to heat : Seunggitang(承氣湯) and Majainwhan(麻子仁丸) [2] Constipation due to stagnation of Ki : Samatang(四磨湯) and Yukmatang(六磨湯) (2) Deficiency type [1] Constipation due to deficiency of Ki : Whanggitang(黃?湯) [2] Constipation due to deficiency of blood: Yunjangwhan(潤腸丸) [3] Constipation due to cold : Jechunjun(濟川煎) and Banyuwhan(半硫丸) 2) Enema therapy: It is a method to induce defecation by honey or pig's bile juice for weak people. 3) Acupuncture and Moxibustion: Acupoints used to treat constipation are BL25, ST25 and TE6. Moxibustion at CV8, CV6 is good for constipation due to cold. (4) Diet therapy: It is very important that we eat meals regularly and defecate on the same time even if you don't. And we have to eat food like fruits, vegetables and beans. (5) finger pressure: Finger pressing around these points like ST25, SP25, BL25, BL31, BL32, BL33 and BL34 is good for it. (6) Kigong therapy: Abdominal breathing (7) Old man' s constipation: Hip bath or diet therapy is commended. Laxation with lubricant like Supungyunjangwhan(搜風潤腸丸) is used. (8) Women' s constipation: After delivery, we have to administer tonifying prescription Sipjundaebotang(十全大補湯) and enema can be used. Conclusion : We have to examine the cause of disease and bowl movement carefully. After comprehensive analysis of the data gained by the four methods of diagnosis, we diagnose and treat patients on the base of overall of symptoms and signs.

• Korean journal of communication and information
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• v.48
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• pp.170-190
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• 2009

The aim of this study is to examine the ideological orientation of Minjujungbo which was the first and the largest newspaper in Busan during the U.S. Military Government in Korea. For this purpose this study analyzed the personal history of the editorial staffs and the coverage of the three historical events. The events analyzed were the supporting statement to trusteeship by Korean Communist Party in Jan. 1946, the money counterfeit by Jungpansa in May, 1946 and the general strike in Sep. 1946. The coverages of Minjujungbo on these three events were compared with those of other newspapers which had shown the orientation of the rightist, the neutral, and the leftist respectively. Most of the editorial staffs had been involved the leftist movement but were not socialist to the core at that time. Most of them were the members of Pusanilbo which was published by Japanese in late colonial period. The coverages of Minjujungbo were analyzed to be similar to those of Seoulsinmun which was evaluated as the neutral. But the coverage of the general strike was analyzed as leftist slightly. In conclusion it can be said that the ideological orientation of Minjujungbo was the left-of-center.

• 전자공학회논문지 IE
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• v.49 no.1
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• pp.12-17
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• 2012

Fast development of ubiquitous technology prompted the broadening of the related application area. Application of ubiquitous techniques and system into the construction sites may give us many benefits. There are always a lot of hazard situations in construction sites, and the falling is known to have the high accident rate. To prevent the falling, there has been a lot of efforts including safety education and use of safety gears. In this study, we designed, fabricated and tested a system that can monitor the worker's safety and location informations in real time by using the wireless technology of TOA and RSSI. We used ATmegal28 that is popular in the industrial equipments as MCU and NanoPan 5357 module from Nanotron and CC2500 chipset from TI for radio circuits. We also used 3-axis accelerometer and pressure MEMS sensors to obtain the environmental information, and therefore to aquire the informations of the worker's movement and altitude. We used Labview software from National Instrument to monitor and control the system. We developed the system to send the warning alarms to the server operator and the workers when the workers in the danger zone did not wear the safety hook.

• Journal of the Institute of Electronics Engineers of Korea SC
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• v.45 no.5
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• pp.28-34
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• 2008

The real-time biomedical signal monitoring is a very important factor to realize the ubiquitous healthcare environment. Most of these devices for monitoring the biomedical information get the PPG signal from the user, and these signals are utilized for monitoring their health. It is inconvenient to get the PPG because the user should wear the finger probe with his finger for measuring the PPG signal. Also it is difficult to get the PPG correctly, because of the motion artifacts from the movement of the user. In this paper, we develop the watch type biomedical signal monitoring system without the finger probe, and propose the new algorithm for reducing the motion artifacts from the PPG signal. We designed the system which gets the PPG from the sensor on the wrist band strip. As compared with the finger probe type, this system we proposed is more affected by the motion artifacts. So to filter this motion artifacts, we propose the new method; the improved PMAF(Periodic Moving Average Filter) method.

• Journal of the korean academy of Pediatric Dentistry
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• v.39 no.4
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• pp.390-396
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• 2012

Infraocclusion is defined as tooth whose relative occlusal movement was blocked during the period of active eruption due to ankylosis and so on. Then infraoccluded tooth remains under the occlusal plane composed by adjacent structures showing normal eruption patterns. Untreated infraocclusion may cause: prolonged retention of infraoccluded teeth; extrusion of apposed teeth; destruction of periodontal tissues by occlusal force and food packing; increased sensitivity for dental caries; and disturbances on eruption pathway of succedaneous teeth. Therefore, periodic check-ups and proper treatments are required. There are many treatment options on infraoccluded deciduous molars such as periodic observation, conservative method, restoration and space regaining with extraction of the teeth. The choice of treatment may depend on the presence of succedaneous teeth, time of diagnosis and degree of infraocclusion. In this case report, three patients showing displacement of the second premolars due to infraocclusion of upper second primary molars, were treated by means of space regaining with removable orthodontic appliances and extraction of ankylosed primary molars. All malpositioned permanent premolars in the 3 cases showed ordinary eruption pathways after treatment.