• Journal of the Korean Society of Physical Medicine
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• v.11 no.2
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• pp.103-114
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• 2016

PURPOSE: The purpose of this study was first to develop a Korean version of pediatric functional muscle testing for children with a motor developmental disorder who have a communication problem and who are aged below five years, and also to verify the content validity. METHODS: First, the preliminary study was conducted to verify the reliability of pediatric functional muscle testing, developed by Venita in Korea. Based on the results of the study, the primary evaluation items were selected and modified. Second, the first test of content validity was conducted through a panel discussion, and a second investigation of content validity was carried out by utilizing the Item Content Validity Index (I-CVI). In this study, we selected only 0.78 or more items from I-CVI. RESULTS: Based on the results of the preliminary study, 19 primary evaluation items were selected. Based on the results of the first and second content validity tests, 15 tertiary evaluation items for the Korean version of pediatric functional muscle testing were determined. CONCLUSION: This study developed a new Korean version of pediatric functional muscle testing and suggested that it will be a useful tool to measure muscle strength for Korean children with a motor developmental disorder and a communication problem, aged below five years.

• Journal of Life Science
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• v.22 no.5
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• pp.613-620
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• 2012

To evaluate the effects of sleep habits on the powers of beta waves and the sensory motor rhythm of the electroencephalogram (EEG), female college student subjects were divided into four groups, according to their sleep habits, as follows: GSHG (Good Sleep Habit Group), CSHG (Common Sleep Habit Group: late bedtime), CSDG (Cognitive Sleep Disorder-Delayed Sleep Phase Syndrome Group), and NSDG (Non-cognitive Sleep Disorder-Delayed Sleep Phase Syndrome Group). Brain function was stimulated by reading a book for 3 min in the morning (9~12 am) and the EEG was measured. According to the results, the powers of the beta waves and sensory motor rhythm were not different during the resting period among the four groups. However, during the reading stimulation period, the powers of beta waves and the sensory motor rhythm in the GSHG were significantly greater than in the other groups ($p$ <0.05). Beta powers during stimulation also increased in all brain areas in the GSHG ($p$ <0.05). Interestingly, these were decreased in the frontal and temporal lobes in the CSHG by the reading stimulation ($p$ <0.05). On the other hand, sensory motor rhythm, which represents focusing efficacy, only improved in the GSHG. These results indicate that the brain's focusing function during the reading stimulation was not properly operating in the morning in the female college students who had a delayed bedtime and bad sleep habits.

• The Journal of Korean Academy of Sensory Integration
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• v.1 no.1
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• pp.25-37
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• 2003

Objective : To explore the effectiveness of sensory integration program of home-based outcomes in child with sensory modulation disorder. Methods : This study used the simple case study. The subjects were three children diagnosed as developmentally delayed who 14 month and 26 month males and a 15 month female. After initial evaluation, parents were educated on sensory diet and Wilbarger protocol method for 30 minutes twice for home-based treatment and asked to make out daily treatment planning. To measure improvement of children, we used for the Denver Developmental Screening Test II(DDST II), Wee Functional Independence Measure(WeeFIM), hand function, functional ability, oral motor function, Sensory Profile(Dunn, 1999). Results : After the home-based program, the scored of the Denver Developmental Screening Test II(DDST II), Wee Functional Independence Measure(WeeFIM), hand function, functional ability, oral motor function, Sensory Profile(Dunn, 1999) were higher rather than initial evaluation after the home-based program. Conclusion : The home-based program is effective for children with sensory modulation disorder but parents had to be educated by therapist specific evaluation and treatment in sensory integration.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.34 no.4
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• pp.236-241
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• 2023

Objectives: According to the 10th revision of the International Classification of Diseases, the main categories of tic disorders (F95.0, F95.1, and F95.2) follow a diagnostic hierarchy based on the duration and diversity of tic symptoms. The present study investigated the use of this diagnostic hierarchy in real-world clinical practice. Methods: Based on the National Health Insurance Service-National Health Information Database, the diagnosis of transient tic disorder (F95.0) made after a diagnosis of chronic motor or vocal tic disorder (F95.1) or Tourette's syndrome (F95.2) and diagnosis of chronic motor or vocal tic disorder (F95.1) made after a diagnosis of Tourette's syndrome (F95.2) were referred to as type A errors. The diagnosis of transient tic disorder (F95.0) repeated after a period of >12 months was referred to as type B error. Demographic and clinical differences according to the diagnostic error types were analyzed using analysis of variance, Student's t-tests, and chi-squared tests. Results: Most participants (96.5%) were without errors in the diagnosis of tic disorders. Higher proportions of males (p=0.005) and antipsychotic prescriptions (p<0.001) were observed in patients with type A or B diagnostic errors. A higher proportion of health insurance holders was observed among those with type A errors (p=0.027). Conclusion: Errors were absent in majority of the tic diagnoses in real-world clinical practice in terms of the diagnostic hierarchy.

• Korean Journal of Biological Psychiatry
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• v.13 no.4
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• pp.299-304
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• 2006

Objectives : The purpose of the present study was to investigate whether the TaqI A polymorphism of dopamine receptor D2 gene(DRD2) is associated with Tourette syndrome(TS) and chronic motor tic disorder(CMT) in Korean population. Methods : DRD2 TaqI A RFLP genotyping was carried out with DNA extracted from blood samples of 75 patients with tic disorders(47 with TS and 28 with CMT) and 90 healthy subjects. Genotype and allelic frequencies for the DRD2 gene polymorphisms of the tic disorder group as a whole were compared to those of the control group. Separating the TS group, thereafter, the frequency of genotypes and alleles were compared to those of the controls. Results : The results demonstrated that genotype and allele distributions for the DRD2 gene polymorphism in the tic disorder as a whole, TS, and control groups were not significantly different. Conclusion : No association was found for DRD2 gene, TS and CMT. The data suggest that DRD2 gene may not be a useful marker for the prediction of the susceptibility of tic disorder.

• The Journal of Korean Physical Therapy
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• v.28 no.4
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• pp.232-242
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• 2016

Purpose: This study was conducted to develop a Korean version of the pediatric functional muscle test (K-PFMT) for children with motor developmental disorders, and to verify its reliability and validity. Methods: The subjects were 40 children, aged below 5 years. Each was scored on the K-PFMT by 14 physical therapists to determine inter-rater reliability and internal consistency. Additionally, 3 of the 14 therapists tested 20 children again one or two weeks later to determine test-retest reliability. The internal consistency was calculated by Cronbach's alpha. The inter-rater and test-retest reliability were calculated using the intraclass correlation coefficient (ICC). One-way ANOVA and the paired t-test were used to compare differences among the three evaluator groups and between the test and retest group. Concurrent validity was evaluated by Pearson's correlation with a total score of GMFM. Results: Chronbach's alpha was over 0.98 for each test item and 0.99 for the total items. There was no significant differences in the score of K-PFMT among the three evaluator groups except for a few items. The test-retest ICC was from 0.89 to 1.00 and from 0.82 to 1.00, respectively. There was no significant difference between the test and retest group, except for a few items. There were high significant correlations between K-PFMT and GMFM. Conclusion: This study showed that a K-PFMT with relatively high reliability and validity was successfully developed. The K-PFMT will be a useful tool for measurement of muscle strength of children with motor developmental disorder.

• BMB Reports
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• v.51 no.1
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• pp.3-4
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• 2018

Parkinson's disease (PD) is a debilitating disorder resulting from loss of dopamine neurons. In dopamine deficient state, the basal ganglia increases inhibitory synaptic outputs to the thalamus. This increased inhibition by the basal ganglia output is known to reduce firing rate of thalamic neurons that relay motor signals to the motor cortex. This 'rate model' suggests that the reduced excitability of thalamic neurons is the key for inducing motor abnormalities in PD patients. We reveal that in response to inhibition, thalamic neurons generate rebound firing at the end of inhibition. This rebound firing increases motor cortical activity and induces muscular responses that triggers Parkinsonian motor dysfunction. Genetic and optogenetic intervention of the rebound firing prevent motor dysfunction in a mouse model of PD. Our results suggest that inhibitory synaptic mechanism mediates motor dysfunction by generating rebound excitability in the thalamocortical pathway.

• The Journal of Pediatrics of Korean Medicine
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• v.29 no.1
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• pp.50-59
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• 2015

Objectives The purpose of this study is to report seven cases of autism spectrum disorder treated by oriental medicine. Methods Seven patients who are diagnosed with autism spectrum disorder were treated with herbal medicine (Kwakhyangjungkisanhapyukmijihwangtang-gamibang), and the effect was measured. Results After the treatment, cognitive skill, speech, motor function, communication skill, and the patients' general conditions have gotten better. Conclusions This study has shown that the oriental medical treatment for autism spectrum disorder was effective, but further studies are needed.

• Speech Sciences
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• v.7 no.1
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• pp.97-107
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• 2000

Motor aphasia is an affection frequently caused by insult of the left middle cerebral artery and usually accompanied by a large lesion involving the Broca's area and the adjacent motor and premotor areas. Therefore, a patient with motor aphasia commonly shows articulatory disturbances due to failure of the motor programing of speech sound. Objective assessment and treatment of phonologic programing is one of the important aspects of speech therapy in aphasic patients. We analyzed the speech disorders acompanied with motor aphasia in a 45-year-old man using a computerized sound spectrograph, Visi-$Pitch{\circledR}$, and Multi-Dimensional Voice $Program{\circledR}$. We concluded that a computerized speech analysis system is a useful tool to visualize and quantitatively analyse the severity and progression of dysarthria, and the effect of speech therapy.

• Journal of Korean Physical Therapy Science
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• v.13 no.2
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• pp.121-127
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• 2006

Consideration for therapy method and oral motor function character of children with cerebral palsy. Therapists who treat for feeding disorder children owing the regression of oral motor function are necessary to gain knowledge about dysfunction of sensing, perception and cognition with baffling to eat and inhibition of primitive reflex, oral anatomy and function, and motor control (trunk, head, positioning of the upper limbs and the lower limbs and muscle tone). Oral motor function program is a comprehensive rehabilitation program which requires systematized enforcement and collaborated attempts to physiotherapists, occupational therapists, speech therapists, psychotherapists. Especially, physical therapists are not accustomed to oral motor program, hoping to provide diffusely and apply new therapy approach method for many areas (bell's palsy, respiratory failure, speech articulation). It will comprise to study owing to holistic approach with clinic.