• 대한치과교정학회지
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• 제25권2호
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• pp.209-221
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• 1995

한국인에게 적합한 설측교정장치와 이상적인 설측 치열궁 아치와이어 제작의 기초자료를 얻기위하여 정상교합자 경석고 모형 30개를 재료로 하여 설측치관의 형태와, 후지타 설측 브라켓을 위치시킨 모형에서 설측치열궁 형태를 조사하여 다음과 같은 결과를 얻었다. 각 치아에 대한 치관의 근원심 경사도와 설면의 순설측 치관 경사도의 평균치를 얻었다. 각 치아에 대한 브라??? 위치에서 설면의 수평 및 수직적 형태를 얻은 결과 대구치, 소구치, 견치는 상하악이 비슷한 모양을 보였으며, 강하악의 중절치와 측절치도 비슷한 모양을 보여 각각 브라켓 기저부를 공유할 수 있을 것으로 나타났다. 브라켈 부착위치에서의 평균 설측치열궁 형태를 얻은 결과, 그 형태는 전치부는 반원형이며 견치와 소구치 사이에 강한 오프??? 밴드가 있는 버섯 형태로서 소구치간 및 제2소구치와 대구치간에도 오프??? 밴드가 필요한 것으로 나타났다. 남녀간의 평균 설측치열궁 형태는 상악은 거의 일치하였고 하악은 여자가 남자보다 다소 작은 형태를 나타내었다.

• 한국수자원학회논문집
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• 제36권3호
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• pp.507-520
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• 2003

V형 여울은 하천 양안에 설치하여 여울의 가운데로 물의 흐름을 집중시켜 하도 중앙 직하류에 세굴로 인한 소(pool)를 형성하는 역할을 하는 인공 여울이다. V형 여울의 설치 목적은 평탄화된 하도에 소를 형성시켜 갈수시 어류의 서식처 노는 피난처를 제공하고, 홍수시에는 유속이 약한 구간을 발생시켜 어류의 피난처를 제공하는 것이다. 본 연구에서는 V형 여울의 수리 모형 실험을 실시하여 각 조건에 따른 세굴심을 측정하여 세굴 특성을 분석하였고, 나아가 수리량 조건 및 V형 여울 형태와 세굴 간의 정량적인 관계를 실험 결과로부터 도출하였다. 또한 V형 여울과 형태가 유사한 수제에서의 세굴심에 대한 기존의 연구 결과와 V형 여울의 경우를 비교하였다. 그 결과 Breusers와 Raudkivi(1991)가 제안한 수제에서의 세굴심 예측식은 V형 여울에서의 세굴심을 과소평가하지만 V형 여울께서의 세굴 특성을 일부 반영하는 것으로 나타났다. V형 여울의 세굴에 영향을 주는 인자들의 무차원화를 통해 V형 여울에서의 세굴심 예측식을 제안하였고 제안된 예측식은 V형 여울의 적용에 있어서 세굴심을 추정하는데 사용될 수 있고 판단된다. V형 여울의 세굴에 지배적인 영향을 주는 인자는 여울 중앙에서의 프루드 수이고, 그밖에 여울과 흐름의 각도와 여울 개구부의 폭도 부분적으로 영향을 준다.

• 대한치과기공학회지
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• 제31권1호
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• pp.23-36
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• 2009

The goal of esthetic restoration is to achieve morphologic, optical, and biologic acceptance. Creation of a natural looking ceramic restoration, which blends harmoniously with surrounding dentition, is not always achieved. A successful color match is an important aspect of any esthetic dental restoration. Since natural enamel has inherent translucency, it is important that ceramic restorations reproduce the translucency and color of the natural teeth. However, the final color match of porcelain crowns to adjacent natural dentition remains some problem. Difficulties related to color matching arise from the structural differences that exist between metal ceramic crowns and natural teeth, the limited range of available ceramic shades, inadequate shade guides, different types of metal alloys, repeated firing, the condensation technique, and varying compositions of ceramic materials. Many factors contribute to the esthetic success of dental restoration: optical properties such as color and its elements of hue, value, and chroma; translucency and opacity; light transmission and scattering; and metamerism and fluorescence. The purpose of this study was to determine the color changes of metal-ceramic system with different veneering porcelain powder after repeated firing. The objectives of this in vitro study were to measure the lightness($L^*$), chromaticity($a^*$), chromaticity($b^*$), chroma($C^*$), hue(h), reflectance(%), color difference(${\Delta}E$). The following conclusions were obtained: 1. An increase in the number of firings resulted in decrease in lightness($L^*$) but increase in chromacticity($a^*$) with all porcelain. After the second sintering resulted in decrease in chromacticity($b^*$) with opaque-dentin porcelain and dentin porcelain but in increase with enamel porcelain and translucency porcelain. And after the second sintering resulted in decrease in chroma($C^*$) with opaque-dentin porcelain and dentin porcelain, but on the whole side in decrease with enamel porcelain and translucency porcelain. 2. After the second firing, a increase in the number of firings resulted in decrease reflectance(%) in all wavelength. 3. There were noticeable color differences(${\Delta}E$) between first sintering and multiple firings(dentin porcelain: 5.29~8.15, opaque-dentin porcelain: 4.83~8.2, enamel porcelain: 8.93~13.15, translucency porcelain: 9.37~12.91), but the color difference(${\Delta}E$) after second sintering were down to 4.87 in all porcelain. 4. Given the NBS Criteria, a 'trace' was not found this study but a 'slight' was found 2-3, 3-5 in dentin porcelain, 2-3 in opaque-dentin porcelain, 3-5, 5-10 in enamel porcelain and translucency porcelain, a 'noticeable' was 2-5, 3-10, 5-10 in dentin porcelain and opaque-dentin porcelain, 2-3, 2-5, 3-10 in enamel porcelain 2-3, 3-10 in translucency porcelain, an 'appreciable' was 1-2, 1-3, 2-10 in dentin porcelain 1-2, 1-3, 2-10, 3-10 in opaque-dentin porcelain, 2-10 in enamel porcelain, 2-5, 2-10 in translucency porcelain, a 'much' was 1-5, 1-10 in dentin porcelain and opaque-dentin porcelain, 1-2, 1-3, 1-5 in enamel porcelain 1-2, 1-3, 1-5, 1-10 in translucency porcelain, a 'very much' was 1-10 in enamel porcelain.

• 생물정신의학
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• 제25권3호
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• pp.60-71
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• 2018

Objectives A growing body of evidence has suggested that morphologic changes in cerebellum may be implicated with pathophysiology of major depressive disorder (MDD). The aim of this study is to investigate a difference in the volume and cortical thickness of the specific region of cerebellum between patients with MDD and healthy controls (HC). Methods A total of 127 patients with MDD and 105 HC participated in this study and underwent T1-weighted structural magnetic resonance imaging. We analyzed volume and cortical thickness of each twelve cerebellum regions divided by left and right and the volume and cortical thickness of the whole cerebellum from T1-weigted image of participants. One-way analysis of covariance was used to investigate the volume and cortical thickness difference of total and specific regions between two groups adjusting for age, gender, medication, and total intracranial cavity volume. Results We found that the patients with MDD had significantly greater volume in the left cerebellum lobule III region [false discovery rate (FDR)-corrected p = 0.034] compared to HC. Also, our findings indicate that cortical thickness of left lobule VIIB (FDR-corrected p = 0.032) and lobule VIIIB (FDR-corrected p = 0.032) are significantly thinner in the patients with MDD compared with the HC. No significant volume and cortical thickness differences were observed in other sub-regions of the cerebellum. The volumes and cortical thickness of whole cerebellum between patients with MDD and HC did not differ significantly. Conclusions We observed the region-specific volume and cortical thickness difference in cerebellum between the patients with MDD and HC. The results of our study implicate that the information about structural alterations in cerebellum with further replicative studies might provide a stepping stone toward a specific marker to diagnose MDD.

• Archives of Plastic Surgery
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• 제34권3호
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• pp.279-284
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• 2007

Purpose: The vein graft was considered as a useful conduit for nerve defect. But the problem is that it might be collapsed in long vein graft state. A new experimental model using vein graft filled with hyaluronic acid was considered. Methods: Thirty rats were used for the experimental animal. In group I, one side of the femoral nerve was exposed and a segment was removed about 15mm. The neural gap was connected with nerve graft. In group II, the nerve gap was connected with vein graft only. In group III, the nerve gap was connected with vein graft filled with hyaluronic acid. A walking track analysis was made periodically for 2 months and NCV(nerve conduction velocity) was executed at the end of the experiment. And morphologic studies were also done for all groups Results: In a walking track analysis, the toe-spread was widen and the foot-length was lengthened. The recovery of the toe-spread and foot length was checked 2 weeks interval, periodically for two months. The SFI (sciatic function index) was $-52.5{\pm}8.2$ in group I, $-68.1{\pm}4$ in group II, $-55.3{\pm}7.9$ in group III. In electrophysiological study, NCV(nerve conduction velocity) was $26.71{\pm}3.11m/s$ in group I, $17.94{\pm}4.35m/s$ in group II, $25.69{\pm}2.81m/s$ in group III. The functional recovery in group I and III was superior to that the group II statistically(p < 0.05) Under electromicroscopic study, the number of the myelinated axons were $1419.1{\pm}240$ in group I, $921.7{\pm}176.8$ in group II, $1322.2{\pm}318$ in group III. The number of the myelinated axons were much more in group I and III than group II statistically (p<0.05). Conclusion: This study suggested that the vein graft filled with hyaluronic acid is more effective than vein graft only for the conduit of the nerve gap. It was thought that the technique could be used in clinical cases with nerve defects as an alternative method to classical nerve grafts.

• 한국가축번식학회지
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• 제15권1호
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• pp.23-32
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• 1991

本 硏究는 한국 在來山羊에 있어서 分娩後 子宮粘膜 및 膣粘膜上皮의 形態學的 變化를 알아보기 위하여 遂行하였다. 子宮 및 膣은 分娩直後 및 分娩後 1, 3, 10 및 21日에 光學顯微鏡的으로 觀察하였던 바 다음과 같은 結果를 얻었다. 1. 光學顯微鏡的 觀察에서는 子宮粘膜上皮細胞의 높이는 分娩後 時間이 經過함에 따라서 減少하는 傾向이었으며 apocrine樣 分泌像은 分娩後 1日부터 10日째에 觀察되었다. Trichrom染色에서 明照細胞와 暗照細胞의 出現頻度는 分娩後 1日째에 多數 觀察되었으나 21日째에는 小數 觀察되었고 PAS 陽性細胞는 小數가 出現하였으나 分娩後 21日째에는 觀察되지 않았다. 한편 分娩後 1日째에 子宮粘膜上皮細胞間 또는 上皮下에서 globule leucocyte(GL)가 多數 觀察되었으나 그후는 약간 減少하였고 分娩後 10日째부터 上皮細胞에서 空胞內에 crystalline樣 構造가 觀察되었다. 2. 膣粘膜上皮細胞의 높이는 分娩後 3日째에 가장 높았고 時期가 經過함에 따라 減少하였으며 肥滿細胞의 出現頻度는 時期가 經過함에 따라 增加하였다. 分娩後 3日째와 10日째의 膣粘膜上皮의 表層細胞는 立方形을 나타내었으며 分娩後 10日과 21日째에 粘膜上皮細胞內에 空胞가 觀察되었다.

• Journal of Yeungnam Medical Science
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• 제18권1호
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• pp.112-122
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• 2001

구순 구개열을 가지는 성인 남자 17명의 두 부계측방사선 사진을 McNamara씨 분석법을 중심으로 하여 정상 대조군과 비교하여 다음과 같은 결론을 얻었다. 구순 구개열 환자에서 Na. perpendicular to point A. SNA angle이 통계적으로 유의하게 작게 나와 두개저에 대해 상악이 후방에 위치하였다(p<0.01). Effective maxillary length, Maxillomandibular differential, Wit's appraisal 등이 구순 구개열 환자와 대조군에서 통계적으로 유의하였으나 Effective mandibular length, Mandibular plane angle, Facial axis angle, Lower anterior facial height 등은 유의하지 않았다. 이는 하악의 경사도, 성장방향 등은 정상이나 상악의 절대적인 길이가 작으며 이로 인하여 상하악간의 부조화가 생긴 것으로 사료된다. 구순 구개열 환자에서 pogonion to Na. perpendicular가 95% 신뢰구간에서 통계적으로 유의하게 작게 나와 하악이 두개저에 대해 상대적으로 후방에 위치하였다. 교정치료에도 불구하고 point A에 대해 상악 전치가 상대적으로 후방에 위치하였다.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제32권4호
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• pp.137-143
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• 2021

Objectives: Despite the growing concern regarding the adverse effects related to problematic smartphone use (PSU), little is known about underlying morphologic changes in the brain. The brainstem is a deep brain structure that consists of several important nuclei associated with emotions, sensations, and motor functions. In this study, we sought to examine the difference in the volume of brainstem substructures among adolescents with and without PSU. Methods: A total of 87 Korean adolescents participated in this study. The PSU group (n=20, age=16.2±1.1, female:male=12:8) was designated if participants reported a total Smartphone Addiction Proneness Scale (SAPS) score of ≥42, whereas the remaining participants were assigned to the control group (n=67, age=15.3±1.7, female:male=19:48). High-resolution T1 magnetic resonance imaging was performed, and the volume of each of the four brainstem substructures [midbrain, pons, medulla, and superior cerebellar peduncle (SCP)] was measured. Analysis of covariance was conducted to reveal group differences after adjusting for effects of age, gender, whole brainstem volume, depressive symptoms, and impulsivity. Results: The PSU group showed a significantly smaller volume of the SCP than the control group (F=8.273, p=0.005). The volume of the SCP and the SAPS score were negatively correlated (Pearson's r=-0.218, p=0.047). Conclusion: The present study is the first to reveal an altered volume of the brainstem substructure among adolescents with PSU. This finding suggests that the altered white matter structure in the brainstem could be one of the neurobiological mechanisms underlying behavioral changes in PSU.

• 대한세포병리학회지
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• 제1권1호
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• pp.1-17
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• 1990

Hepatocellular carcinoma (HCC) is malignant tumor frequently occurring in Koreans. There have been few reports regarding the cytologic findings of fine needle aspiration (FNA) of HCC. Most have suggested a diagnostic problem in the cytology distinguishing HCC from some benign hepatic lesions-for example, a regeneration nodule in cirrhosis and liver cell adenoma. In spite of its high frequency in Korea, no cytologic study has been reported, concerning the FNA of HCC. In an attempt to achieve cytologic criteria for the diagnosis of HCC, the authors studied retrospectively cytopathologic findings of 247 cases of HCC. These cases were confirmed either by histoiogic examination including lobectomy, biopsy, or ceil block material, or, when tissue diagnosis was unavailable, by a high serum alpha-fetoprotein level (over 400 I. U.). All aspiration smears were stained by the Papanicolaou method. In each case, the smears were analyzed for cell patterns and various cytomorphology of the tumor cells. The smear background was assessed for the presence of tumor cell necrosis and inflammatory components and compared to that of metastatic carcinomas. The cell patterns were classified as trabecular, acinar, dispersed, and irregular. The cytologic parameters analyzed included the degree of nuclear atypia and the presence of mitoses, intranuclear cytoplasmic inclusions, nucleolar prominency, endothelial lining, multinucleated giant cells, eosinophiic globules, bile, and Mallory body. Most of the FNA of HCC showed markedly cellular smears. The tumor cells were most frequently arranged in a trabecular pattern (80.3%). The irregular (12.6%), the acinar (5.5%), and the dispersed patterns (1.7%) followed in decreasing frequency. Individual hepatoma cells were larger than normal liver cells. However, they had morphologic features characteristic of the hepatic cells the cells were round or polygonal, their cytoplasm was abundant and granular with eosinophilic or amphophilic stainability, and their nuclei were round to oval, located centrally, and tended to have prominent nucleoli. Anaplasia and pleomorphism of tumor cells were generally mild to moderate. These findings existed even in very well differentiated cases. Mitotic figures were present in about 85% of the cases. Prominent nucleoli were observed only in about half the cases. The frequency of other cytologic features was as follows intranuclear cytoplasmic inclusion in 86.8% : endothelial lining in 56.1% : bile in 19.8% : and giant cells in 60.1%. Clear cells were often present in 11.7%, Most aspiration smears of HCC displayed clean background without necrosis or inflammatory material in contrast to the dirty, necrotic background of metastatic cancers and cholangiocarcinomas. Based on the above mentioned features, it is suqqested that the cytologic critieria most important for the diagnosis of HCC include a markedly cellular smear, trabecular pattern, hepatocytoid appearance of tumor cells, endothelial lining, the presence of bile, giant cells, intranuclear cytoplasmic inclusions, and prominent nucleoli, Among these, trabecular pattern, endothelial lining, giant cells and clean smear background are points to be considered in differentiating HCC from metastatic and cholangiocellular carcinoma.

• 대한본초학회지
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• 제29권6호
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• pp.15-20
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• 2014

Objectives : Commiphora myrrha (CM) has been used in traditional medicine for treating disease such as obesity, hyperlipidemia, atherosclerosis, diabetes and osteoarthritis. However, the protective effects of CM on acute pancreatitis (AP) has not been reported. Thus, the aim of this study was to evaluate the protective effects of CM water extract on cerulein-induced AP. Methods : AP was induced in mice via intraperitoneal injection of supramaximal concentrations of the stable cholecystokinin analogue cerulein ($50{\mu}g/kg$) every hour for 6 times. Water extract of CM (0.1, 0.2, or 0.5 g/kg) was administrated intraperitoneally 1 h prior to the first injection of cerulein. The mice were killed at 6 h after the final cerulein injection. Pancreas was rapidly removed for morphologic and histochemical examination, myeloperoxidase (MPO) assay. Blood samples were taken to determine serum amylase and lipase activities. Results : Administration of CM significantly inhibited pancreatic weight/body weight ratio, pancreas histological injury. And CM administration inhibited the serum digestive enzyme elevation such as amylase and lipase on cerulein-induced pancreatitis. In addition, Pancreas MPO activity which indicates neutrophil infiltration was inhibited by CM extract on cerulein-induced pancreatitis. Conclusions : In conclusion, our results could suggest that pre-treatment of CM reduces the severity of cerulein-induced AP. Therefore, CM could be used as a protective agent against AP. Also, this study could give a clinical basis that CM could be a drug or agent to prevent AP.