• Journal of Korean Foot and Ankle Society
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• v.1 no.1
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• pp.23-29
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• 1997

Freiberg's disease is a pathologic condition of the second or third metatarsal head, rarely the forth or fifth metatarsal head, and it becomes abnormally enlarge due to avascular necrosis of subchondral cancellous bone. From Nov. 1982 to Sep. 1994, we treated surgically 10 cases of the disease who complained the continuous symptoms inspite of proper conservative management. Metatarsal head excision was done in 8 cases and resurfacing of the cartilagenous portion of the metatarsal head in 2 cases. During the average follow up of 55 months, the pain was relieved in all patients who were underwent surgical intervention but the stiffness of the metatarsophalangeal joint was remained in most of cases. It seems to be a logical treatment of choice in younger and active patients that conservative management is the initial treatment but more ablative procedure is needed for the continued symptoms. We can propose the metatarsal head excision or resurfacing of the involved joint is effective treatment method with simple procedure and minimize morbid period than other procedures such as corrective osteotomy.

• Journal of Korean Academy of Nursing
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• v.43 no.5
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• pp.579-586
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• 2013

Purpose: This article provides an update and overview of a nursing research program focused on understanding the pathophysiology and management of irritable bowel syndrome (IBS). Methods: This review includes English language papers from the United States, Europe, and Asia (e.g., South Korea) from 1999 to 2013. We addressed IBS as a health problem, emerging etiologies, diagnostic and treatment approaches and the importance of a biopsychosocial model. Results: IBS is a chronic, functional gastrointestinal disorder characterized by recurrent episodes of abdominal pain and alterations in bowel habit (diarrhea, constipation, mixed). It is a condition for which adults, particularly women ages 20-45, seek health care services in both the United States and South Korea. Clinically, nurses play key roles in symptom prevention and management including designing and implementing approaches to enhance the patients' self-management strategies. Multiple mechanisms are believed to participate in the development and maintenance of IBS symptoms including autonomic nervous system dysregulation, intestinal inflammation, intestinal dysbiosis, dietary intolerances, alterations in emotion regulation, heightened visceral pain sensitivity, hypothalamic-pituitary-adrenal dysregulation, and dysmotility. Because IBS tends to occur in families, genetic factors may also contribute to the pathophysiology. Patients with IBS often report a number of co-morbid disorders and/or symptoms including poor sleep. Conclusion: The key to planning effective management strategies is to understand the heterogeneity of this disorder. Interventions for IBS include non-pharmacological strategies such as cognitive behavior therapy, relaxation strategies, and exclusion diets.

• Tuberculosis and Respiratory Diseases
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• v.70 no.2
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• pp.143-149
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• 2011

Background: Stopping medical treatment by tuberculosis (TB) patients prior to completing treatment period is a major concern in private hospitals. We evaluated the impact of public-private mix (PPM) project on increasing treatment success rate of TB in a private tertiary hospital in Korea. Methods: Starting in February 2009, TB patients treated at Dankook University Hospital received health education and case monitoring activities by specially trained public health nurses (PPM project). On a retrospective basis, we reviewed medical records and compared the treatment outcome of TB patients treated under the PPM project (PPM group) to patients treated without the PPM project (control group) between January 2008 and June 2010. In addition, we also evaluated the risk factors treatment non-completion. Results: The number of patients in the PPM group and control group were 123 (85 pulmonary TB and 38 extrapulmonary TB) and 146 (101 pulmonary TB and 45 extra-pulmonary TB), respectively. The PPM group had demographic and clinical findings comparable to those of control group. The PPM group showed a significantly higher treatment success rate (93.5%) compared to the control group (77.9%). However, development of complications, proximity to the hospital, and presence of co-morbid disease did not influence the treatment success rate. Conclusion: The PPM project was effective at increasing the TB treatment success rate. An effort to improve and to expand the PPM project is needed in private Korean hospitals.

• Clinical and Experimental Pediatrics
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• v.54 no.2
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• pp.55-63
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• 2011

Prader-Willi syndrome (PWS) is a complex multisystem genetic disorder that is caused by the lack of expression of paternally inherited imprinted genes on chromosome 15q11-q13. This syndrome has a characteristic phenotype including severe neonatal hypotonia, early-onset hyperphagia, development of morbid obesity, short stature, hypogonadism, learning disabilities, behavioral problems, and psychiatric problems. PWS is an example of a genetic condition caused by genomic imprinting. It can occur via 3 main mechanisms that lead to the absence of expression of paternally inherited genes in the 15q11.2-q13 region: paternal microdeletion, maternal uniparental disomy, and an imprinting defect. Over 99% of PWS cases can be diagnosed using DNA methylation analysis. Early diagnosis of PWS is important for effective long-term management. Growth hormone (GH) treatment improves the growth, physical phenotype, and body composition of patients with PWS. In recent years, GH treatment in infants has been shown to have beneficial effects on the growth and neurological development of patients diagnosed during infancy. There is a clear need for an integrated multidisciplinary approach to facilitate early diagnosis and optimize management to improve quality of life, prevent complications, and prolong life expectancy in patients with PWS.

• The Journal of Korean Medicine
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• v.37 no.3
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• pp.1-12
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• 2016

Objectives: The abdominal examination is a diagnosis method for determining a morbid condition of the chest and abdomen by touching and pressing. This study reviewed research trends concerning the abdominal examination and suggested of future research directions for quantification of abdominal examination. Methods: A systematic literature search was carried out for relevant articles published between 2000 and 2016 in five databases such as Korean studies Information Service System(KISS), Oriental Medicine Advanced Searching Integrated System(OASIS), DataBase Periodical Information Academic (DBpia), National Digital Science Library and PubMed based on the Keywords 'abdominal examination'. Results: 128 articles were collected for analysis. Overview on the abdominal examination based on selected 17 articles. Then selected articles have been reclassified by diseases of clinical research and parameters for diagnosis of abdominal examination. Conclusions: Taken together, instrument for quantitative evaluation of abdomen characteristic fit to the traditional Korean Medicine have not yet developed. It is suggested that in order to dominate the market about abdominal examination in advance, more concern should be paid to establishing appropriate development of quantitative criteria and instrument. This review will help researcher to systematically understand and to develop Korean medical device as globally competitive device.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.15
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• pp.6289-6292
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• 2015

Purpose: To determine the biological behaviour of common odontogenic cystic lesions by analysing and comparing bcl-2 expression amongst them. Materials and Methods: Our study covered 90 formalin fixed paraffin embedded tissue samples: 26 primary cases each of radicular cysts (RC), dentigerous cysts (DC) and odontogenic keratocysts (OKC) and 12 of recurrent OKCs. Bcl-2 expression was analysed immunohistochemically and data analysis was accomplished using SPSS version 17.0. Means were taken for age while for gender and site of the lesions frequencies and percentages were determined. The Chi-square test was applied to evaluate any statistically significant difference of bcl-2 expression in these lesions and p value of ${\leq}0.05$ was taken as significant. Results: All the recurrent OKCs showed a strong positivity for bcl-2 that was absent in all of its primary cases (p value<0.05). Although variation in expression of bcl-2 was not found to be statistically significant between RC and DC, however, it became significant when all primary cases of these common odontogenic lesions were compared. Conclusions: Recurrent OKC showed comparatively a more aggressive behaviour than their primary counterparts and also from RC and DC. Bcl-2 proved to be a valuable adjunct in determining aggressive biological behaviour of odontogenic lesions.

• The Journal of the Acoustical Society of Korea
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• v.14 no.5
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• pp.94-101
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• 1995

In this paper, a new vocal cords model, called a four-mass model, is proposed for a hoarse speech mechanism. Pathological changes of vocal cords cause hoarse speech and glottal waveform reflects motion states of vocal cords. From these facts, we assumed that the morbid vocal cords be dissymmetric and take the four-mass type. The glottal waveforms and the model parameters of normal and hoarse speech signals are analyzed, and some relations bet ween the model parameters and the hoarse pathology are discussed. Experimental results show that the new research method of hoarse speech can reveal relations between the acoustic features of hoarse speech and the hoarse pathology, and be used to diagnose laryngeal diseases and to improve tone quality of hoarse speech.

• Korean Journal of Agricultural Science
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• v.17 no.2
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• pp.142-145
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• 1990

A six months old, sika deer with metatarsal bone fracture was referred to the veterinary teaching hospital of Chungnam National University. Midshaft femoral amputation was performed. The sika deer was satisfactorily anesthetized with 1.2mg of xylazine per kg of body weight by intramuscular injection. Procedures of operation was same with those of midshaft femoral amputation in dogs. The sika deer revealed inconveniency in rising, walking and galloping just after operation but they became skilled after a month. After amputation morbid sign was not observed for about 6 months up to nowadays.

• The Korean Journal of Emergency Medical Services
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• v.8 no.1
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• pp.161-168
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• 2004

The workers of limestone industry have relatively higher rate of accident and injury than other industry workers. This survey was conducted to provide the informations for the planning of safety and health educations to prevent the accident and injury. The purpose of this study is to identify the morbidity rate per month and to determine the related health factors, and to find accident experiences of the limestone workers and to analyze the reasons and types of that accidents. The study design was a descriptive survey. Self reporting questionnaires developed by researcher were used for data collection. The subjects of this study were 225 workers in limestone industries in Jecheon city. The statistical methods utilized for data analysis were frequency analysis, $x^2$-test with SPSS-pc(ver.9.0). The results are as follows, 1. The workers morbidity rate per month was 22%, and morbid factors were Flu., G-I trouble, hypertension, orthopedic trauma, external wound, burn, etc., and the related health factors are self-assessment for health, exercise, accessability for medical facilities. 2. 40% of the subjects have experienced the accidents during last 6 months. The types of the accidents were safety violations, traffic accidents and fire accidents. Injury types were external wounds, fracture/amputation and burn. The workers of limestone industry have higher morbidity rate and experiences of accidents. Therefore the more increased safety and health educations than now for both the workers and the managers are needed. And this study could be helpful to increase the quality and the quantity of the educations needed.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.13
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• pp.5423-5425
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• 2014

Purpose: To evaluate the risk factors for endometrial hyperplasia concomitant endometrial polyps in pre- and post-menopausal women. Materials and Methods: A total of 203 patients undergoing endometrial sampling before hysterectomy were evaluated in this retrospective study. Data recorded were age, gravidity, parity, body mass index (BMI: weight(kg)/$height(m)^2$), endometrial thickness (ET), menopausal status, presence of adenomyosis and diabetes mellitus. Results: Endometrial hyperplasia and polyps were detected in 13 patients. There were statistically significant differences in terms of age, menopausal status, morbid obesity and diabetes mellitus (p<0.005). Logistic regression demonstrated that menopausal status and presence of diabetes mellitus were independent risk factors. Conclusions: According to the current study; menopause and diabetes mellitus are strong risk factors for the presence of concomitant endometrial polyps and endometrial hyperplasia.