• Korean Journal of Radiology
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• v.25 no.8
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• pp.726-741
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• 2024

Recent advancements in Alzheimer's disease treatment have focused on the elimination of amyloid-beta (Aβ) plaque, a hallmark of the disease. Monoclonal antibodies such as lecanemab and donanemab can alter disease progression by binding to different forms of Aβ aggregates. However, these treatments raise concerns about adverse effects, particularly amyloid-related imaging abnormalities (ARIA). Careful assessment of safety, especially regarding ARIA, is crucial. ARIA results from treatment-related disruption of vascular integrity and increased vascular permeability, leading to the leakage of proteinaceous fluid (ARIA-E) and heme products (ARIA-H). ARIA-E indicates treatment-induced edema or sulcal effusion, while ARIA-H indicates treatment-induced microhemorrhage or superficial siderosis. The minimum recommended magnetic resonance imaging sequences for ARIA assessment are T2-FLAIR, T2^* gradient echo (GRE), and diffusion-weighted imaging (DWI). T2-FLAIR and T2^* GRE are necessary to detect ARIA-E and ARIA-H, respectively. DWI plays a role in differentiating ARIA-E from acute to subacute infarcts. Physicians, including radiologists, must be familiar with the imaging features of ARIA, the appropriate imaging protocol for the ARIA workup, and the reporting of findings in clinical practice. This review aims to describe the clinical and imaging features of ARIA and suggest points for the timely detection and monitoring of ARIA in clinical practice.

• Journal of Sensor Science and Technology
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• v.22 no.1
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• pp.71-75
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• 2013

Nuclear containment building is used as second blockage to protect us from a radiation leakage caused by the natural disaster or any accidents, so it's safety is important and must be kept with continuous surveillance. In this study, we measured the strain of a nuclear containment building's wall by using FBG sensor and investigated the structural safety of a nuclear containment building. 50 FBG strain sensors and 18 FBG strain sensors were attached on the side wall and upper dome of a nuclear containment building, respectively. We measured the strains of the outside concrete wall during the Structural Integrity Test (SIT) of a nuclear containment building. The strain of an upper dome was larger than that of a side wall, about $200{\mu}{\varepsilon}$. And the very small strain was measured at vertical direction of a side wall. These experimental results were used to evaluate the structural health of nuclear containment building.

• Journal of Positioning, Navigation, and Timing
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• v.2 no.1
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• pp.33-40
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• 2013

In this paper, GPS signal anomaly generation software is proposed which can be used for the analysis of GPS signal anomaly effect and the design, verification, and operation test of anomalous signal monitoring technique. For the implementation of anomalous signal generation technique, anomalous signals are generated using a commercial signal generation simulator, and their effects and characteristics are analyzed. An error model equation is proposed from the result of analysis, and the anomalous signal generation software is constructed based on this equation. The proposed anomalous signal generation software has high scalability so that users can easily utilize and apply, and is economical as the additional cost for purchasing equipment is not necessary. Also, it is capable of anomalous signal generation based on real-time signal by comparing with the commercial signal generation simulator.

• Journal of Navigation and Port Research
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• v.35 no.9
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• pp.701-706
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• 2011

Radio waves including GPS signals, various TV communications, and radio broadcasting can be disturbed by a strong solar storm, which may occur due to solar flares and produce an ionospheric delay anomaly in the ionosphere according to the change of total electron content. Electron density irregularities can cause deep signal fading, frequently known as ionospheric scintillation, which can result in the positioning error using GPS signal. This paper proposes a detection algorithm for the ionosphere delay anomaly during a solar storm by using multi-reference stations. Different TEC grid which has irregular electron density was applied above one reference station. Then the ionospheric delay in zenith direction applied different TEC will show comparatively large ionospheric zenith delay due to the electron irregularity. The ionospheric slant delay applied an elevation angle at reference station was analyzed to detect the ionospheric delay anomaly that can result in positioning error. A simulation test was implemented and a proposed detection algorithm using data logged by four reference stations was applied to detect the ionospheric delay anomaly compared to a criterion.

• Smart Structures and Systems
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• v.21 no.6
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• pp.741-749
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• 2018

Structural health monitoring (SHM) systems are necessary to achieve smart predictive maintenance and repair planning as well as they lead to a safe operation of mechanical structures. In the context of vibration-based SHM the measured structural responses are employed to draw conclusions about the structural integrity. This usually leads to a mathematically illposed inverse problem which needs regularization. The restriction of the solution set of this inverse problem by using prior information about the damage properties is advisable to obtain meaningful solutions. Compared to the undamaged state typically only a few local stiffness changes occur while the other areas remain unchanged. This change can be described by a sparse damage parameter vector. Such a sparse vector can be identified by employing $L_1$-regularization techniques. This paper presents a novel framework for damage parameter identification by combining sparse solution techniques with an Extended Kalman Filter. In order to ensure sparsity of the damage parameter vector the measurement equation is expanded by an additional nonlinear $L_1$-minimizing observation. This fictive measurement equation accomplishes stability of the Extended Kalman Filter and leads to a sparse estimation. For verification, a proof-of-concept example on a quadratic aluminum plate is presented.

• Proceedings of the Korea Association of Information Systems Conference
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• 1997.10a
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• pp.503-525
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• 1997

정보시스템 아웃소싱(outsourcing)의 적용 범위와 그 규모가 증대함에 따라, 아웃 소싱은 정보시스템의 관리에서 근본적인 이슈로 등장하게 되었다. 정보시스템 아웃소싱의 중요성이 인식되었으나, 그에 대한 실증적 연구는 매우 미흡한 설정이다. 본 연구의 주요 목적은 정보시스템 아웃소싱에 있어 고객회사(client firm)와 서비스 제공업자(vendor)간의 관계의 성공 및 실패에 영향을 미치는 요인을 조사하는 것이다. 본 연구의 연구 모델은 관 계적거래이론(relational exchange theory), 커뮤니케이션 행동(communication behavior), 거래비용분석(transaction cost analysis) 등의 조직간관계(interorganizational relationship) 이론에 기반을 두고 작성되었다. 미국의 207개 회사의 정보시스템 아웃소싱 설문조사에 의 하여 다음과 같은 연구결과가 도출되었다. (1) 서비스 제공업자의 능력(vendor capability), 관계결속성(solidarity), 관계지속성(continuity expectation), 유연성(flexibility), 서비스업자의 활동에 대한 모니터링(monitoring of the vendor), 참여도(participation) 등이 아웃소싱 관 계의 성공과 양의 상관관계를 가지고 있으며, (2) 역할연합도(role integrity), 자산특이성 (asset specificity) 등은 아웃소싱 관계의 성공과 음의 관계를 가지고 있는 것으로 나타났 다. 이 결과에 의하면, 비관계적 거래(discrete exchange) 보다는, 관계적 거래(relational exchange)에 기반을 두어 아웃소싱 관계를 운영하는 것이 아웃소싱의 성공적인 구현을 필 수적으로 보여진다. 이 연구 결과를 기초로 하여 아웃소싱 대상 업무의 선택, 서비스 제공 업자의 선택, 그리고 아웃소싱 관계의 지속적인 관리를 위한 지침을 제시하였다.

• Proceedings of the Korean Reliability Society Conference
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• 2001.06a
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• pp.235-238
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• 2001

It is well known that the reliability of materials of mechanical products is becoming more and more important not only for assurance of quality, but for international competition of products. In order to assure the reliability of materials or mechanical products nondestructive evaluation (NDE) techniques are playing more important roles. The existence of Internal defects in materials or mechanical parts is served as crack initiation site during the various loading condition. Historically, nondestructive evaluation (NDE) technique has been used almost exclusively for detecting microscopic discontinuities In materials or mechanical parts after they have been in service to expand the role of the NDE to include all aspects of materials production and application. Research efforts are being directed at developing and perfecting NDE techniques capable of monitoring (1) materials production processes (2) material integrity following transport, storage and fabrication and (3) the amount and rate of degradation during service. In addition, efforts are underway to develop technique capable of quantitative discontinuity sizing, permitting determination of response using fracture mechanics analysis, as well as techniques for quantitative materials characterization to replace the qualitative techniques used in the past. In this paper, the important role of NDE technology for reliability assurance of materials/mechanical parts is introduced.

• Aerospace Engineering and Technology
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• v.6 no.1
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• pp.230-236
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• 2007

The quality control of composite structure includes inspection, testing and monitoring in all processes from receiving inspection to part fabrication. The purpose of these activities is to ensure that the design objectives are consistently achieved. The quality factors include material, receiving inspection, storage and shelf-life control, environmental control, testing, inspection and record control. This paper presents the process verification method using destructive test and quality control method in composite structure of aircraft. And it is believed that the destructive test will be basis to obtain a reliability of non-destructive test in complex composite structure and to ensure the design requirements in composite part.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.24 no.4 s.175
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• pp.858-865
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• 2000

It is well recently recognized that quench is one of the serious problems for the integrity of superconducting magnets, which is mainly attribute to the rapid temperature rising in the magnet due to some extrinsic factors such as conductor motion, crack initiation etc. In order to apply acoustic emission(AE)echnique effectively to monitor and diagnose superconducting magnets, it is essential to identify the sources of acoustic emission. In this paper, an acoustic emission technique has been used to monitor and diagnose quenching phenomenon in racetrack shaped superconducting magnets at cryogenic environment of 4.2K. For these purposes special attention was paid to detect AE signals associated with the quench of superconducting magnets. The characteristics of AE parameters have been analyzed by correlating with quench number, winding tension of superconducting coil and charge rate by transport current. In addition, the source location of quench in superconducting magnet was also discussed on the basis of correlation between magnet voltage and AE energy.

• Journal of the Korean Society of Manufacturing Technology Engineers
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• v.23 no.1
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• pp.27-31
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• 2014

This paper describes a tomographic imaging technique for evaluating the thickness reduction of a plate-like structure using a noncontact sensor network based on an electromagnetic acoustic transducer that generates shear horizontal plate waves. Because this technique is based on the effect of mode cutoff and time of flight of guided waves caused by a change in thickness, the tomographic image provides information on the presence of defects in the structure. To verify the performance of the method, artificial defects with various thickness reduction ratios were machined in an aluminum plate, and the tomographic imaging results are reported. The results show that the generated tomographic image displays the thickness reductions and can identify their locations. Therefore, the proposed technique has good potential as a tool for health monitoring of the integrity of plate-like structures.