• 제목/요약/키워드: monacolin K biosynthetic gene cluster

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Some Monascus purpureus Genomes Lack the Monacolin K Biosynthesis Locus

  • Kwon, Hyung-Jin;Balakrishnan, Bijinu;Kim, Yeon-Ki
    • Journal of Applied Biological Chemistry
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    • 제59권1호
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    • pp.45-47
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    • 2016
  • Two Monascus purpureus genomes lack the monacolin K biosynthesis locus (mok), while Monascus species are generally assumed to be monacolin K producers. These M. purpureus harbor a fusion of mokA and mokB orthologues. This finding suggests that an ancestral mok locus underwent a deletion event in the M. purpureus genome.