• Title/Summary/Keyword: moment analysis

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Segmentation Method of Overlapped nuclei in FISH Image (FISH 세포영상에서의 군집세포 분할 기법)

  • Jeong, Mi-Ra;Ko, Byoung-Chul;Nam, Jae-Yeal
    • The KIPS Transactions:PartB
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    • v.16B no.2
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    • pp.131-140
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    • 2009
  • This paper presents a new algorithm to the segmentation of the FISH images. First, for segmentation of the cell nuclei from background, a threshold is estimated by using the gaussian mixture model and maximizing the likelihood function of gray value of cell images. After nuclei segmentation, overlapped nuclei and isolated nuclei need to be classified for exact nuclei analysis. For nuclei classification, this paper extracted the morphological features of the nuclei such as compactness, smoothness and moments from training data. Three probability density functions are generated from these features and they are applied to the proposed Bayesian networks as evidences. After nuclei classification, segmenting of overlapped nuclei into isolated nuclei is necessary. This paper first performs intensity gradient transform and watershed algorithm to segment overlapped nuclei. Then proposed stepwise merging strategy is applied to merge several fragments in major nucleus. The experimental results using FISH images show that our system can indeed improve segmentation performance compared to previous researches, since we performed nuclei classification before separating overlapped nuclei.

Synthesis, Magneto-Spectral, Electrochemical, Thermal Characterization and Antimicrobial Investigations of Some Nickel(II) Complexes of Hydrazones of Isoniazid (Isoniazid의 hydrazone을 갖는 몇 가지 니켈(II) 착물들의 합성, 자기적 및 전기적 성질, 열적 특성과 항균성에 대한 연구)

  • Prasad, Surendra;Agarwal, Ram K.
    • Journal of the Korean Chemical Society
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    • v.53 no.6
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    • pp.683-692
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    • 2009
  • The synthesis of a novel series of nickel(II) complexes with new ligands derived from hydrazones of isoniazid have been reported in present work. The complexes have general compositions [$Ni(L)_2X_2$] or $[Ni(L)_3](ClO_4)_2$ {L = N-isonicotinamido-furfuraldimine (INH-FFL), N-isonicotinamido-3',4',5'-trimethoxybenzaldimine (INH-TMB) or N-isonicotinamido-cinnamalidene (INH-CIN) and X = $Cl^-$, ${NO_3}^-$, $ NCS^-$ or $CH_3COO^-$}. The ligands hydrazones behave as neutral bidentates (N and O donor) through the carbonyl oxygen and azomethine nitrogen. The new complexes with octahedral geometry have been characterized by elemental analysis, molecular weight determinations, magnetic susceptibility/moment, thermogravimetric, electrochemical and spectroscopic studies viz. infrared and electronic spectra. On the basis of conductivity measurements in nitrobenzene ($PhNO_2$) solution the [$Ni(L)_2X_2$] and $[Ni(L)_3](ClO_4)_2$ complexes have been found to be non-electrolytes and 1:2 electrolytes, respectively. Thermal properties have also been investigated, which support the geometry of the complexes. Antibacterial and antifungal properties of nickel(II) complexes and few standard drugs have also been examined and it has been observed that the complexes have moderate antibacterial activities.

Buckling Analysis of Stiffened Plates with Elastic Supports Subjected to In-Plane Bending Moment Considering Warping of End Stiffeners (지지단 보강재의 뒤틀림을 고려한 면내휨을 받는 탄성지지 보강판의 좌굴해석)

  • 이용수
    • Computational Structural Engineering
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    • v.10 no.1
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    • pp.135-148
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    • 1997
  • The main objective of this paper is to analyze the rectangular stiffened plates with two opposite ends elastically restrained and the others simply supported subjected to in-plane bending by Finite Element Method. Another objective is to develope Classical Method analyzing the unstiffened rectangular plates with the above boundary conditions. In order to validate finite element and classical methods, the buckling strengths of the rectangular plates with four simply supported ends, and with two simply supported and the others fixed ends by finite element method and classical method are compared with those of references. In finite element method, elastically restrained ends can be obtained as considering torsional and warping rigidities of end stiffeners. The buckling strengths of the rectangular plates with elastically restrained ends by finite element and classical methods are calculated and compared with each other. In case of stiffened plates, to validate finite element method, the buckling strengths of the rectangular stiffened plates with four simply supported ends, and with two simply supported and the others fixed ends are also compared with those of references. The buckling strengths of the rectangular stiffened plates with elastically restrained ends by finite element method are calculated as solving eigenvalue problems which are obtained as assembling rectangular plate elements and beam elements considered torsional and warping rigidities. The buckling strengths of rectangular stiffened plates according to various positions of rectangular intermediate stiffener, J and I/sub w/ of end stiffeners are also obtained, which are compared to determine the efficient position of intermediate stiffener.

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The Study of Aerial Triangulation Using GPS (GPS를 이용한 사진기준점 측랑에 관한 연구)

  • 이재원;문두열;김정희;김진수
    • Spatial Information Research
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    • v.12 no.2
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    • pp.181-191
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    • 2004
  • Nowadays, GPS-photogrammetry can be applied to the basemap production, a land register and NGIS. And from now on, as the increase of GPS receiver rate, the study on the interpolation methods considering the exact movement of an aircraft at photoflight and the study on the supplement of GPS defect by INS are required continuously. GPS-Photogrammetry, which are based on the direct measurement of the projection centers and attitude at the moment of camera exposure time through loading the GPS receiver in aircraft. This photogrammetric methods can of for us to acquire the exterior orientation parameters with only minimum ground control points, even the ground control process could be completely skipped. Consequently, we can drastically reduce the time and cost far the mapping process. In this thesis, two test flights were conducted in area to evaluate the performance of accuracy and efficiency through the analysis of results between the two photogrammetric methods, that is, traditional photograrammetry, GPS-Photogrammetry. Test results shows that a large variety of advantages of GPS-Photogrammetry against traditional photogrammetry is to be verified. Especially, the number of ground control points for the exterior orientation could be saved more than 70~80%, and the cost far map production 30~50%, respectively. In addition, it was convinced that the large reduction of control points has not any effect on the block accuracy.

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Crystallographic and Magnetic Properties of Li0.5Fe2.5-χRhχO4 by Using Applied Field Mossbauer Spectrometer (외부자기장 뫼스바우어 분광기를 이용한 Li0.5Fe2.5-χRhχO4의 자기적 성질과 결정학적 구조에 관한 연구)

  • Kang, Kun-Uk;Kim, Chul-Sung
    • Journal of the Korean Magnetics Society
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    • v.14 no.6
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    • pp.219-223
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    • 2004
  • L $i_{0.5}$F $e_{2.5-{\chi}}$R $h_{\chi}$ $O_4$ ($\chi$ = 0.25, 0.50, 0.75, 1.00) has been prepared by solid state reaction. Crystallographic and magnetic properties were investigated by Mossbauer spectroscopy, SQUID magnetometry, and x-ray diffraction. The crystal structure is found to be a cubic spinel structure with space group Fd3m for all the samples. The lattice constant $a_{0}$ increases from 8.3365 $\AA$ to 8.3932 $\AA$ with increasing Rh concentration $\chi$. The migration of Li ion has been confirmed by x-ray patterns and the results of applied field Mossbauer analysis. The temperature dependence of the absorption area of each site was analyzed with the Debye model for the recoil-free fraction. The Debye temperature for the octahedral sites is almost as large as for the tetrahedral sites, thereby suggesting similar inter-atomic binding forces for the octahedral and the tetrahedral sites. The saturated magnetic moment and the Mossbauer spectra taken at 4.2 K under the applied field (6 T) show that the spin structure of L $i_{0.5}$F $e_{2.5-{\chi}}$R $h_{\chi}$ $O_4$ is compatible with the collinear Neel Model.

Seismic Performance-based Design using Computational Platform for Structural Design of Complex-shaped Tall Building (전산플랫폼을 이용한 비정형 초고층 건축물 성능기반 내진설계기술의 실무적용)

  • Lee, Dong-Hun;Cho, Chang-Hee;Youn, Wu-Seok;Kang, Dae-Eon;Kim, Taejin;Kim, Jong-Ho
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.26 no.1
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    • pp.59-67
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    • 2013
  • Complex-shaped tall building causes many structural challenges due to its structural characteristics regarding inclined members and complexed shape. This paper is aimed at development of design process using computational-platform which is effective design tool for responding frequent design changes, particularly as to overseas projects. StrAuto, a parametric structural modeling and optimizing system, provides the optimized alternatives according to design intent and realize a swift process converting a series of structural information necessary to nonlinear analytical models. The application of the process was to a 45-story hotel building in Ulanbator, Mongolia adopting shear wall and special moment frame with outrigger systems. To investigate the safety of lateral force resisting system against maximum considered earthquake(MCE), nonlinear response history analysis was conducted using StrAuto.

Evaluation of Wave Characteristics and JONSWAP Spectrum Model in the Northeastern Jeju Island on Fall and Winter (제주도 북동부 연안에서 추동계 파랑특성과 JONSWAP 스펙트럼의 적용성 평가)

  • Kang, Dong-Hyub;Lee, Byung-Gul
    • Journal of the Korean Society for Marine Environment & Energy
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    • v.17 no.2
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    • pp.63-69
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    • 2014
  • Analysis frequency spectrum through observed wave data in northeastern shore, jeju island, during winter and fall, and review wave characteristics. In order to compute maximum wave height, we calculate the ratio of significant wave height to maximum wave height using the linear regression equation. In addition, for calculating JONSWAP spectrum, we assumed ${\gamma}$ value using significant wave height and peak frequency in the observation area. Consequently, the highest frequency is below 1 m in the case of significant wave height and during the first observation, the mean of height was estimated at 0.523 m and during the scend observation, it was 0.423 m. Furthermore, in peak frequency, the highest frequency was 0.12 Hz~0.15 Hz (period is nearly 6.67s~8.33s), the results of ${\gamma}$ from using significant wave height and peak frequency is 2.72 and the significant wave height calculated by straight linear regression equation was $1.635H_s$.

Hydrological Studies on the flood and Risk of failure of the Hydraulic Structures(Ⅰ) -On the annual maximum series- (水利構造物의 破壞危險度와 設計洪水量에 관한 水文學的 硏究(Ⅰ) -年最高値 系列을 中心으로-)

  • Lee, Soon-Hyuk;Park, Myeong-Keun
    • Magazine of the Korean Society of Agricultural Engineers
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    • v.27 no.2
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    • pp.23-37
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    • 1985
  • This studies were carried out to get characteristics of frequency distribution, probable flood flows according to the return periods, and the correlation between return periods and those length of records affect the Risk of failure in the annual maximum series of the main river systems in Korea. Especially, Risk analysis according to the levels were emphasized in relation to the design frequency factors for the different watersheds. Twelve watersheds along Han, Geum, Nak Dong, Yeong San and Seom Jin river basin were selected as studying basins. The results were analyzed and summarized as follows. 1. Type 1 extremal distribution was newly confirmed as a good fitted distribution at selected watersheds along Geum and Yeong San river basin. Three parameter lognormal Seom Jin river basin. Consequently, characteristics of frequency distribution for the extreme value series could be changed in connection with the watershed location even the same river system judging from the results so far obtained by author. 2. Evaluation of parameters for Type 1 extremal and three parameter lognormal distribution based on the method of moment by using an electronic computer. 3. Formulas for the probable flood flows were derived for the three parameter lognormal and Type 1 extremal distribution. 4. Equations for the risk to failure could be simplified as $\frac{n}{N+n}$ and $\frac{n}{T}$ under the condition of non-parametric method and the longer return period than the life of project, respectively. 5. Formulas for the return periods in relation to frequency factors were derived by the least square method for the three parameter lognormal and Type 1 extremal distribution. 6. The more the length of records, the lesser the risk of failure, and it was appeared that the risk of failure was increasing in propotion to the length of return periods even same length of records. 7. Empirical formulas for design frequency factors were derived from under the condition of the return periods identify with the life of Hydraulic structure in relation to the risk level. 8. Design frequency factor was appeared to be increased in propotion to the return periods while it is in inverse proportion to the levels of the risk of failure. 9. Derivation of design flood including the risk of failure could be accomplished by using of emprical formulas for the design frequency factor for each watershed.

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Pseudo-Static Behaviors of U-shaped PSC Girder with Wide Flanges (확폭플랜지를 갖는 U형 프리스트레스 거더의 유사정적거동)

  • Rhee, In-Kyu;Lee, Joo-Beom;Kim, Lee-Hyeon;Park, Joo-Nam;Kwak, Jong-Won
    • Proceedings of the KSR Conference
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    • 2008.11b
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    • pp.993-999
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    • 2008
  • A girder height limitation is the critical parameter for rapid construction of bridge deck and construction space limitation especially in urban area such as high population area and high density habitats. A standard post-tensioned I-shaped concrete girder usually demands relatively higher girder height in order to retain sufficient moment arm between compression force and tensile force. To elaborate this issue, a small U-shaped section with wide flanges can be used as a possible replacement of I-shaped standard girder. This prestressed concrete box girder allows more flexible girder height adjustment rather than standard I-shaped post-tensioned girder plus additional torsion resistance benefits of closed section. A 30m-long, 1.7m-high and 3.63m-wide actual small prestressed concrete box girder is designed and a laboratory test for its static behaviors by applying 6,200kN amount of load in the form of 4-point bending test was performed. The load-deflection curve and crack patterns at different loading stage are recorded. In addition, to extracting the dynamic characteristics such as natural frequency and damping ratio of this girder, several excitation tests with artificial mechanical exciter with un-symmetric mass are carried out using operational frequency sweep-up. Nonlinear finite element analysis of this 4 point bending test under monotonic static load is investigated and discussed with aids of concrete damaged plasticity formulation using ABAQUS program.

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Effect of Cu content on Hot Tearing Susceptibility in Al-Si-Cu Aluminum Casting Alloy (Al-Si-Cu 알루미늄 주조 합금의 열간 균열 민감성에 미치는 Cu 함량의 영향)

  • Oh, Seung-Hwan;Munkhdelger, Chinbat;Kim, Heon-Joo
    • Journal of Korea Foundry Society
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    • v.41 no.5
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    • pp.419-433
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    • 2021
  • Al-Si-Cu alloys benefit from the addition of copper for better hardness and strength through precipitation hardening, which results in remarkably strong alloys. However, the addition of copper expands the solidification range of Al-Si-Cu alloys, and due to this, these alloys become more prone to hot tearing, which is one of the most common and serious fracture phenomena encountered during solidification. The conventional evaluation method of the hot tearing properties of an alloy is a relative and qualitative analysis approach that does not provide quantitative data about this phenomenon. In the present study, the mold itself part of a device developed in Instone et al. was partially modified to obtain more reliable quantitative data pertaining to the hot tearing properties of an Al-Si-Cu casting alloy. To assess the influence of Cu element, four levels of Cu contents were tested (0.5, 1.0, 3.0, and 5.0 wt.%) in the Al-Si-Cu system alloy and the hot tearing properties were evaluated in each case. As the Cu content was increased, the hot tearing strength decreased to 2.26, 1.53, 1.18, and 1.04 MPa, respectively. At the moment hot tearing occurred, the corresponding solid fraction and solidification rate decreased at the same temperature due to the increase in the solid-liquid coexistence range as the Cu content increased. The morphology of the fracture surfaces was changed from dendrites to dendrites covered with residual liquid, and CuAl2 phases were observed in the vicinity of hot tearing.