• Title/Summary/Keyword: molecules

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Nano-Encapsulation of Fluorescent Dyes in Diblock Copolymer Micelles

  • Yoo, Seong-Il;Zin, Wang-Cheol;Sohn, Byeong-Hyeok
    • Proceedings of the Polymer Society of Korea Conference
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    • 2006.10a
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    • pp.193-193
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    • 2006
  • Fluorescent dyes were encapsulated in the nanometer-sized diblock copolymer micelles to control the fluorescence resonance energy transfer. Since acceptor molecules and donor molecules were effectively isolated in the independent micelles, the energy transfer between donors and acceptors was suppressed by the site isolation, leading to the simultaneous emission from both donor and acceptor molecules.

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Biological Roles of Alternative Autophagy

  • Shimizu, Shigeomi
    • Molecules and Cells
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    • v.41 no.1
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    • pp.50-54
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    • 2018
  • Atg5 and Atg7 have long been considered as essential molecules for autophagy. However, we found that cells lacking these molecules still form autophagic vacuoles and perform autophagic protein degradation when subjected to certain stressors. During this unconventional autophagy pathway, autophagosomes appeared to be generated in a Rab9-dependent manner by the fusion of vesicles derived from the trans-Golgi and late endosomes. Therefore, mammalian autophagy can occur via at least two different pathways; the Atg5/Atg7-dependent conventional pathway and an Atg5/Atg7-independent alternative pathway.

Bonding Behavior of Carbon Black/Nylon 66 Hybrid Nanofiber Webs via Microwave Heating (카본블랙/나일론 66 혼합 나노섬유웹의 마이크로파에 의한 접착거동)

  • Shin, Dong-Ho;Joo, Chang-Whan
    • Proceedings of the Korean Fiber Society Conference
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    • 2003.10b
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    • pp.114-117
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    • 2003
  • Conventional heating the heat source cause the molecules to react from the surface toward the center so that successive layers of molecules heat in turn. The product surfaces may be in danger of over heating by the time heat penetrates the material. Microwave, however, produce a volume heating effect. All molecules are set in action at the same time. It also evens temperature gradients and offers other important benefits such as selective heating. (omitted)

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Study on the microwave heating on kevlar fiber-bonding using Polyvinylidene floride(PVDF) (Polyvinylidene floride(PVDF)를 이용한 케블라 섬유접착에 마이크로웨이브에 관한 연구)

  • Young-Soo Lee;Jin-Ah Lee;Chang-Whan Joo
    • Proceedings of the Korean Fiber Society Conference
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    • 2001.10a
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    • pp.403-404
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    • 2001
  • In conventional heating, the heat source causes the molecules to react from the surface toward the center so that successive layers of molecules heat in turn. In the microwave heating, which is produced a volume heating effect, all molecules are set in action at the same time. And, It also evens temperature gradients without the concern of material thickness. (omitted)

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Possible Misinterpretation in Surface Adsorption Studies by CP-MAS NMR

  • Han, Oc-Hee;Bae, Yoon-Kyung
    • Journal of the Korean Magnetic Resonance Society
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    • v.12 no.1
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    • pp.60-64
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    • 2008
  • Cross-polarization (CP) signals were observed even from liquid samples such as neat toluene. Therefore, CP signals of liquid molecules in the presence of high surface materials do not necessarily mean the molecules are adsorbed on solid surface, especially when no signal from the tertiary observing nuclei such as carbons of the molecules is detected.

Intercalation of Functional Organic Molecules with Pharmaceutical, Cosmeceutical and Nutraceutical Functions into Layered Double Hydroxides and Zinc Basic Salts

  • Hwang, Seong Ho;Han, Yang Su;Choe, Jin Ho
    • Bulletin of the Korean Chemical Society
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    • v.22 no.9
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    • pp.1019-1022
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    • 2001
  • Negatively charged functional organic molecules such as retinoic acid, ascorbic acid, indole acetic acid, citric acid, salicylic acid, acidic dye (indigo carmine, Food Blue 1) are intercalatively encapsulated by zinc basic salt (hydrozincite) and layered double hydroxide. Such functional organic-inorganic nanohybrids are realized via coprecipitation reaction involving simultaneous formation of layered inorganic lattice and intercalation of anionic species. The heterostructural nature of these nanohybrids, their particle morphology and textural characterizations are mainly discussed on the basis of Powder X-ray Diffraction and Field Emission Scanning Electron Microscopy results.

Collisional Excitation using Metastable Helium Jet Produced in a Graphite Tube Nozzle

  • 최익순;하영미;이상국
    • Bulletin of the Korean Chemical Society
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    • v.18 no.12
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    • pp.1285-1288
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    • 1997
  • The graphite tube nozzle has been developed for the generation of metastable He jet by which the nitrogen molecules initially excited in a jet with Engelking type nozzle have been further excited in a corona excited supersonic expansion. The excitation process of nitrogen molecules in the jet collision has been discussed in detail by observing the emission intensity from the vibronic emission spectra of nitrogen molecules and nitrogen molecular ions upon helium jet collision.

Molecular Reorientation of Oblate Symmetric Top Molecules with Internal Extended Rotational Diffusion

  • Shin, Kook-Joe Shin
    • Bulletin of the Korean Chemical Society
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    • v.4 no.5
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    • pp.228-230
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    • 1983
  • Molecular reorientation of oblate symmetric top molecules with internal rotation is investigated theoretically and an analytic expression for the overall reorientational correlation time in terms of the internal angular momentum correlation time is derived. This expression is quite different from the expression for prolate symmetric top molecules but reduces to the same expression in the spherical top limit. Fast internal rotation is treated by a modified version of the extended rotational diffusion while the bulky symmetric top mainbody is treated by the rotational diffusion model.

Transfersomes-mediated gene transfer into organs in mice by direct application on intact skin

  • Lee, Eun;Kim, Adele;Kim, Chong-Kook
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.416.2-416.2
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    • 2002
  • Transfersomes are highly detormable hydrophilic lipid vesicles that are able to penetrate the skin barrier so that they can be used to carry low- and high-molecular weight molecules into the body. Until recently. it has been reported that molecules such as insulin. interleukin-2 and several other large molecules have been transported into the body using Transfersomes as a delivery system. Here however, for the very first time, genes (GFP) have been transported into the mice non-invasively using the Transtersomes as a delivery vehicle. (omitted)

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Deep Learning Approach Based on Transcriptome Profile for Data Driven Drug Discovery

  • Eun-Ji Kwon;Hyuk-Jin Cha
    • Molecules and Cells
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    • v.46 no.1
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    • pp.65-67
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    • 2023
  • SMILES (simplified molecular-input line-entry system) information of small molecules parsed by one-hot array is passed to a convolutional neural network called black box. Outputs data representing a gene signature is then matched to the genetic signature of a disease to predict the appropriate small molecule. Efficacy of the predicted small molecules is examined by in vivo animal models. GSEA, gene set enrichment analysis.