• Journal of the Korean Operations Research and Management Science Society
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• v.26 no.1
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• pp.15-32
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• 2001

It is well known that the web design is composed of several factors which are interacting with each other. However, the current approach to web design had been focused on modifying specific factors without considering its impact on other factors. In this sense, we propose more holistic approach to the web design by using fuzzy cognitive map. For this purpose, we form an illustrative fuzzy cognitive map for the web design which is based on the literature, and analyzed and impact of change in a specific factor on other factors. Especially, to improve the output analyzability, we suggested an advanced version of fuzzy cognitive map called stratified fuzzy cognitive map. After simulating the fuzzy cognitive map for web design, we could conclude that our approach is robust and effective compared to the traditional web design approach.

• 한국생물공학회:학술대회논문집
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• 2003.10a
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• pp.717-720
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• 2003

A chromogenic biosensor employing microfluidics on a chip has been developed for the determination of high-density lipoprotein (HDL) cholesterol (HDL-C) in human serum. We have investigated a plain and effective method to immobilize enzymes within the microchip without chemically modifying micro-channel or technically micro-fabricating column reactor and fluid channel network. In assessing risk factors of coronary heart disease, a micro-chip system would minimize requirements of instrument and reagent handling.

• Journal of Korean Biological Nursing Science
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• v.10 no.2
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• pp.121-130
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• 2008

Purpose: This study was undertaken to identify stroke risk with risk factors and knowledge of stork in women with prehypertension. Methods: A total of 46 pre-hypertensive women in urban area aged 44.8 (SD 11.4) yr old in average were selected by a convenient sampling. Demographic data, risk factors, and knowledge of stroke were assessed through face to face interview. Stroke risk scores were calculated based on points given to age, systolic blood pressure, smoking, DM, and heart disease in Framingham stroke risk score. Data were analyzed by SPSS WIN 12.0 using descriptive statistics, two sample t-test, and Pearson's correlation coefficient. Results: The mean systolic blood pressure of participants was 133.11 mmHg, and HDL cholesterol was lower than the recommended level, although rest of physiologic risk factors were within normal. Of the participants, 82% did not do regular physical activity and 75% did not control fat intake persistently. Mean stroke risk points and knowledge scores were 4.48 and 29.15, respectively, which were significantly different between women with and without persistent controlling fat intake. Conclusion: Results indicate stroke prevention intervention for prehypertensive women should address comprehensively modifying lifestyle as well as physiologic factors, and information focusing on stroke risk factors and warning symptoms.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.9
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• pp.5077-5083
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• 2013

Background: Breast cancer is the most frequent cancer in women globally and represents the second leading cause of cancer death among women (after lung cancer). India is going through epidemiologic transition. It is reported that the incidence of breast cancer is rising rapidly as a result of changes in reproductive risk factors, dietary habits and increasing life expectancy, acting in concert with genetic factors. Materials and Methods: In order to understand the existing epidemiological correlates of breast cancer in South India, a systematic review of evidence available on epidemiologic correlates of breast cancer addressing incidence, prevalence, and associated factors like age, reproductive factors, cultural and religious factors was performed with specific focus on screening procedures in southern India. Results: An increase in breast cancer incidence due to various modifiable risk factors was noted, especially in women over 40 years of age, with late stage of presentation, lack of awareness about screening, costs, fear and stigma associated with the disease serving as major barriers for early presentation. Conclusions: Educational strategies should be aimed at modifying the life style, early planning of pregnancy, promoting breast feeding and physical activity. It is very important to obtain reliable data for planning policies, decision-making and setting up the priorities.

• Structural Engineering and Mechanics
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• v.60 no.2
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• pp.237-249
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• 2016

There are constraints on truck weight, axle configurations and size imposed by departments of transportation around the globe due to structural capacity limitations of highway pavements and bridges. In spite of that, freight movers demand some vehicles that surpass the maximum size and legal weight limits to use the transportation network. Oversized trucks serve the purpose of spreading the load on the bridge; thus, reducing the load effect on the superstructure. For such vehicles, often a quick structural analysis of the existing bridges along the traveled route is needed to ensure that the structural capacity is not exceeded. For a wide vehicle having wheel gage larger than the standard 1830 mm, the girder distribution factors in the design specifications cannot be directly used to estimate the live load in the supporting girders. In this study, a simple approach that is based on finite element analysis is developed by modifying the AASHTO LRFD's girder distribution factors for slab-on-steel-girder bridges to overcome this problem. The proposed factors allow for determining the oversized vehicle bending moment and shear force effect in the individual girders as a function of the gage width characteristics. Findings of the study showed that the relationship between the girder distribution factor and gage width is more nonlinear in shear than in flexure. The proposed factors yield reasonable results compared with the finite element analysis with adequate level of conservatism.

• International conference on construction engineering and project management
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• 2011.02a
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• pp.58-65
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• 2011

Construction Productivity is one of the most important elements in construction management. It is used in construction process scheduling and cost management, which are significant sector in construction management. It is important to make appropriate schedule and monitor how works are done within schedule. But construction project contains uncertainty and inexactitude, modifying construction schedule is being an issue to manage construction works well. Even though prediction and monitoring of productivity can be principal activity, it is hard to predict productivity with manager's experience and a standard of estimate. A large number of factors influencing productivity, such as drawing, construction method, weather, labor, material, equipment, etc. But current calculation of productivity depends on empirical probability, not consider difference of each influencing factor. In this research, the aim is to present a productivity predicting regression model of form work, which includes effectiveness of influences factors. 5 variables existed inside form work are selected by interview and site research based on literature review of existed various productivity influencing factors. The effectiveness and correlation of productivity influencing factors are analyzed by statistical approach, and it is used to make productivity regression model. The finding of this research will improves monitoring and controlling of project schedule in construction phase.

• Quality Improvement in Health Care
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• v.3 no.1
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• pp.126-143
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• 1996

Background : Little work has been carried out regarding quality assessment research in a primary care setting, comparing with that of hospitals. This study aims to evaluate the process of diagnosis and management of hypertension by public health doctors on the basis of pre-established clinical guideline, and to identify several modifying factors associated with them. Methods : Hypertension was selected as the target disease, because it is a chronic disease which is of great public health importance. Self-administered questionnaires were mailed to public health doctors practicing at health centers and health subcenters across the nation. The response rate was 20.9%. The questionnaire included the diagnosis and management process such as measuring blood pressure, history taking, physical examinations, and treatment approches and potentially modifying factors such as level of training, duration of practice as a public health doctor, and education on management of hypertension. Results : Public health doctors pay little attention in measuring BP, hypertension related history taking, performing physical examination and laboratory examination. But they devoted much effort in diagnosing hypertension exactly and giving nonpharmacological treatment. Among various antihypertensive drugs, calcium-channel blockers were the most preferred agent(50.9%). Level of training, duration of practice ad a public health doctor, and education on management of hypertension made no difference on quality of care(p>0.05). Conclusion : These public health doctors showed poor compliance with the pre-established clinical guidelines, which leaves much to be desired in diagnosing and managing hypertensive patients by public health doctors. This study might be able to contribute to develop some strategies, such as educational programs, which would be able to improve the process of care in hypertensives.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.13 no.1
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• pp.37-43
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• 1991

Cephalometric prediction tracing is the preoperative double checking procedure which can predict bony and soft tissue change. Soft tissue profile prediction is routinely performed according to the known ratios of the soft to hard tissue movement which can vary considerably in each individual. Besides interindividual variation of the ratios of the soft to hard tissue change, actual results of the postoperative soft tissue profile can reflect other important modifying factors if it is compared with prediction tracing used. The purpose of this study is to compare soft tissue prediction tracing used with postoperative tracing and to find intervening modifying factor via serial tracing. Review of 30 prediction tracing showed that the most important factor contributing to prodiction tracing inaccuracy was the skeletal and dental relapse. And, some factors which may be responsible for prediction tracing inaccuracy were discussed.

• 한국균학회소식:학술대회논문집
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• 2014.10a
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• pp.11-11
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• 2014

Fungal pathogens have huge impact on health and economic wellbeing of human by causing life-threatening mycoses in immune-compromised patients or by destroying crop plants. A key determinant of fungal pathogenesis is their ability to undergo developmental change in response to host or environmental factors. Genetic pathways that regulate such morphological transitions and adaptation are therefore extensively studied during the last few decades. Given that epigenetic as well as genetic components play pivotal roles in development of plants and mammals, contribution of microbial epigenetic counterparts to this morphogenetic process is intriguing yet nearly unappreciated question to date. To bridge this gap in our knowledge, we set out to investigate histone modifications among epigenetic mechanisms that possibly regulate fungal adaptation and processes involved in pathogenesis of a model plant pathogenic fungus, Magnaporthe oryzae. M. oryzae is a causal agent of rice blast disease, which destroys 10 to 30% of the rice crop annually. Since the rice is the staple food for more than half of human population, the disease is a major threat to global food security. In addition to the socioeconomic impact of the disease it causes, the fungus is genetically tractable and can undergo well-defined morphological transitions including asexual spore production and appressorium (a specialized infection structure) formation in vitro, making it a model to study fungal development and pathogenicity. For functional and comparative analysis of histone modifications, a web-based database (dbHiMo) was constructed to archive and analyze histone modifying enzymes from eukaryotic species whose genome sequences are available. Histone modifying enzymes were identified applying a search pipeline built upon profile hidden Markov model (HMM) to proteomes. The database incorporates 22,169 histone-modifying enzymes identified from 342 species including 214 fungal, 33 plants, and 77 metazoan species. The dbHiMo provides users with web-based personalized data browsing and analysis tools, supporting comparative and evolutionary genomics. Based on the database entries, functional analysis of genes encoding histone acetyltransferases and histone demethylases is under way. Here I provide examples of such analyses that show how histone acetylation and methylation is implicated in regulating important aspects of fungal pathogenesis. Current analysis of histone modifying enzymes will be followed by ChIP-Seq and RNA-seq experiments to pinpoint the genes that are controlled by particular histone modifications. We anticipate that our work will provide not only the significant advances in our understanding of epigenetic mechanisms operating in microbial eukaryotes but also basis to expand our perspective on regulation of development in fungal pathogens.

• The Korean Journal of Rehabilitation Nursing
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• v.14 no.1
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• pp.32-38
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• 2011

Purpose: The purpose of this study was to investigate the level of awareness toward disabled persons among nursing students and to identify associating factors for their awareness of disabled persons. Method: 410 nursing students completed the survey on the awareness and frequency of contacts toward disabled persons, self-efficacy, and clinical practice satisfaction. Results: The scores in awareness, contact, clinical practice satisfaction was $50.53{\pm}7.53$, $52.41{\pm}10.61$, $79.21{\pm}10.88$ and $67.04{\pm}9.47$, respectively, indicating. Awareness of disabled persons had significant positive correlations with frequency of contact (p<.001), satisfaction with nursing major (p=.045), satisfaction with clinical practice (p<.001) and self-efficacy (p=.029). Conclusion: To improve awareness of disability, we need to improve student's satisfaction with nursing major and clinical practice by modifying the curriculum. Thereby awareness toward disabled and the weak can improve naturally.