• Asian Pacific Journal of Cancer Prevention
• /
• 제13권9호
• /
• pp.4413-4416
• /
• 2012

Aim: Individual differences in chemosensitivity and clinical outcome in non-small cell lung cancer (NSCLC) patients treatment with platinum-based chemotherapy may be due to genetic factors. Our study aimed to investigate the prognostic role of GSTP1, XRCC1 and XRCC3 in NSCLC patients treated with chemotherapy. Methods: A total of 460 cases were consecutively selected from The Affiliated Hospital of Nantong University between Jan. 2003 to Nov. 2006, and all were followed-up until Nov. 2011. Genotyping of GSTP1 Ile105Val, XRCC1 Arg194Trp, XRCC1 Arg399Gln and XRCC3 Thr241Met was conducted by duplex polymerase-chain-reaction with confronting-two-pair primer methods. Results: Patients with GSTP Val/Val exhibited a shorter survival time, and had a 1.89 fold greater risk of death than did those with the IIe/IIe genotype. For XRCC1 Arg194Trp, the variant genotype Trp/Trp was significantly associated with a decreased risk of death from NSCLC when compared with the Arg/Arg. Individuals carrying XRCC1 399Gln/Gln genotype had a longer survival time, with a lowered risk of death from NSCLC. Conclusion: This study indicated that GSTP1 Ile105Val, XRCC1 Arg194Trp and XRCC1Arg399Gln genes have a role in modifying the effect of platinum-based chemotherapy for NSCLC patients in a Chinese population. Our findings provide information for therapeutic decisions for individualized therapy in NSCLC cases.

• 한국조리학회지
• /
• 제22권1호
• /
• pp.141-152
• /
• 2016

Recently, not only development of curriculum associated directly with job, the development of new education model is in great need. So, the purpose of this study is to develop the instructional design guideline utilizing goal-based scenario(GBS) for college students who major in culinary arts. First, to achieve this goal, we recognized the 7 core elements(learning goal, mission, cover story, role activity, scenario operating, resource, feedback) composing GBS through literature review and case study. Second, we drew a conclusion about the problem and guideline for traditional culinary practice course by conducting inspection about culinary practice environment and needs with professors who are teaching culinary arts. Third, we applied the instructional design guideline for culinary practice to regular classes according to GBS's factors, and then we did formative evaluation with content experts and educational technology expert. Finally, we designed the final instructional design guideline for culinary practice by modifying early model reflected the result of formative evaluation. The results of this study are as following. First, when we applied GBS to culinary practice, professors have to focus on process of materialization by developing easy scenario to students. Also, they have to prepare the class circumstance to feel about sense of realism in advance. Second, to give a conjugally new skill at working, professors's effort is important. culinary practice education at college has responsibility to carry out the vocational training that has competitiveness and difference with labor market's needs. Therefore, it is necessary for us to develop the teaching and learning model for culinary practice which is suitable for major based on the manpower demand for industry without causing job mismatch from demand for industry.

• 동력기계공학회지
• /
• 제13권6호
• /
• pp.95-101
• /
• 2009

The generator for gas turbine power generation consists of the rotor which generates magnetic field, the winding coil which is the path for the field current and the wedge and retaining ring which prevents the radial movement of the coil. Relatively severe deformation was observed at the coil end section during the inspection of the generator for peaking-load operation, and the thermal-electricity and the centrifugal force were evaluated by the simple modeling of the windings to find the cause. But the simulation stress was not sufficient to induce the coil plastic deformation. The analysis result seems to be applicable to the base-load generators which runs continuously without shut down up to a year, but there had been more deformation than simulated for the generator which is started up and shut down frequently. The cause of the coil deformation was the restriction of the expansion and shrinkage. The restriction occurs when the winding coil shrinks, and the stress overwhelms the yield stress and cause the plastic deformation. The deformation is accumulated during the start-ups and shut-downs and the thermal growth occurs. The factors which induce the coil restriction during the expansion and shrinkage should be reduced to prevent the unallowable deformation. The resolutions are cutting off the field current earlier during the generator shut-down, modifying the coil end section to remove the stress concentration and making the insulation plate inserted between the coil end section and the retaining ring have the constant thickness.

• 보건행정학회지
• /
• 제7권1호
• /
• pp.73-99
• /
• 1997

This study was carried out by using questionnaires with 126 insurance societies from Sept. 30, 1995 to Oct. 18, 1995. The primary data collected bythe survey have been significantly supplemented by secondary data obtained from sources such as health insurance statistical year books and internal data in the Ministry of Health and Wolfare. Major findings were summarized as follows: Two financial coordinating programs have significantly improved financial status of regional health insurance societies: the catastrophic program for high cost medical care that was initiated in 1991 and the program for hospitalization cost of the aged in 1995. Another finding is that there existed ambiguity and inconsistency of equity index that had been used by stabilization programs and its side effects could not be ignored. Regression analyses were made to identify factors that affect financial transfers. Inde pendent variables in the regression include utilization frequency, dependancy ration, insurance contribution per insured and medical expense per insured. All these variables were statistically significant in the equations of applying distribution rate (distribution/contribution) and transfer rate (transfer/contribution) as dependent variables. Policy suggestions for the catastrophic program for high cost medical care are modifying the definition of catastrophic case and setting the maximum amount of subsidies for each society based on distribution rates. To solve the problems of the financial coordinating program for the aged, we could consider reimbursing more than 50% of the copayment incurred by the aged 65 or more and determining the maximum amount of outpatient copayment at 10,000 Won per day or per visit for the elderly. More fundamental improvement could be made by amending the Welfare Benefit Act to establish and expand medical and welfare facilities for the elderly.

• 한국융합학회논문지
• /
• 제9권8호
• /
• pp.149-154
• /
• 2018

직업적 음성 사용자들의 범위가 확대됨에 따라 음성에 대한 관심이 증가하고 있다. 특히 교사는 음성장애 위험이 높은 직업군에 포함되기 때문에 음성문제 발생과 음성장애 발병 요인에 대한 규명이 필요하다. 본 연구는 교사의 음성 특성과 음성장애 위험 요인에 대한 체계적 연구 분석을 통해 교사의 음성장애 위험 요인을 확인하고 이를 위한 기초자료를 제공하였다. 2000년부터 2018년까지 '직업', '교사', '직업적 음성 사용자', '음성', '음성장애', '위험' 키워드를 조합하여 414편의 연구가 검색되었으며 그 중 8편의 연구를 최종 분석 대상으로 선정하였다. 질적 평가는 Qualsyst: checklist for assessing the quantitative studies 항목을 수정하여 비뚤림 평가를 실시하였다. 연구 결과 교사는 음성 사용에 있어 음성의 오남용이 자주 발생하였으며 이는 환경에 영향을 받는 것으로 확인되었다. 이러한 결과를 통해 교사의 음성 오남용 환경 개선과 주기적인 음성 교육이 필요함을 제안한다.

• Journal of Biosystems Engineering
• /
• 제34권5호
• /
• pp.351-357
• /
• 2009

This study was conducted to verify the simulation model through the drying test, and investigate effect of factors, such as temperature of drying air, airflow rate, and velocity of the airflow, on the drying. The low temperature drying simulation model was developed based on the circulation dry simulation model presented by Keum et al. (1987), and by modifying low temperature thin layer drying model, equilibrium moisture content model, latent heat of vaporization model, and crack ratio prediction model. The heat pump and experimental dryer with a capacity of 150kg were used for the test. The RMSE between the predicted and measured value was 0.27% (drying temperature), 0.15% (crack ratio), and 2.08% (relative humidity), so the relevance of the model was verified. In addition, the effect of drying temperature, airflow rate, and velocity of the airflow on the drying was examined. The experimental results showed that the crack ratio at drying temperature of $25{\sim}40^{\circ}C$ was allowable. Moreover, at below $30^{\circ}C$, variation of the crack ratio was slight, but drying time was delayed. Given these results, the drying temperature of over $30^{\circ}C$ was effective. As the airflow rate increased, required energy dramatically increased. Whereas drying rate slowly increased, so loss of drying efficiency was caused. Considering these results, the dryer needed to be designed and adjusted to lower than $30\;m^3/min{\cdot}ton$. As velocity of the airflow increased, required drying energy increased when the velocity of the airflow was over $5\;m^3$/hr, while crack ratio and drying rate showed little variation.

• 한국식생활문화학회지
• /
• 제8권1호
• /
• pp.11-19
• /
• 1993

The purposes of this study were to: (a) measure the levels of job satisfaction with five facets of a job: the work itself, promotion, pay, supervision and co-workers and (b) investigate relationships between job characteristics and job satisfaction levels of the dietitians in school foodservice. Subjects consisted of 151 dietitians, with 91 in Seoul and 60 in KyoungKi-Do. The survey form was developed on modifying Job Descriptive Index developed by Smith, Kendall, Hulin and Job Characteristics Inventory developed by Sims, Szilagy, Keller. The responding rate was 81.7%. Data were analyzed for frequencies, means, t-test, ANOVA, Pearson correlation and multiple regression using SPSS PC Package. The results of this study were as follows: 1) Less than a half of the sample(40.9%) were 31 to 35 years, married were 62% and junior college graduates were 33.9%. 2) A striking majority of the respondents(81.7%) ranked work itself as the the most important aspect of their jobs. 3) The dietitians were the most satisfied with work itself, then supervision, co-workers, wage and promotion in decreasing order. 4) In relations of demographic factors to the job satisfaction, satisfactions with wage and co-workers were found significantly related to education. 5) Task identity was the most prevalent job characteristics. 6) The $R^2$ for the multiple regression model was 0.26, indicating that 26% of the variance in job satisfaction could be accounted for the job characteristics. This model showed that friendship of job characteristics made the greatest contributions. The second was variety and the third was dealing with others. Especially dealing with others was negatively related to job satisfaction.

• 복식문화연구
• /
• 제19권3호
• /
• pp.597-611
• /
• 2011

The purpose of this study is to propose a design method for one-piece dress patterns with high body fitness through an appearance evaluation of one-piece dress patterns with the application of the 3D Virtual Clothing System known as i-designer. Measures consisted of an optical illusion effect in visual imagery and mutual influence according to a change in the length and princess line, in a silhouette of a one-piece dress. The data was assessed by a t-test and a multi-way ANOVA and factor analysis using SPSS 17.0. The results were as follows; The design of the study pattern was done by modifying the ease of the bust circumference, ease of the abdominal circumference, ease of the hip circumference, the position of the side seam line, and the appearance of horizontality in the hem line, which received a low evaluation in appearance evaluations of a one-piece dress pattern. As a result of analyzing the visual image according to a change in the length and princess line, in the form of a silhouette of a one-piece dress, four factors were selected; the whole-body optical illusion factor, the upper-body optical illusion factor, the bust optical illusion factor, and the lower-body optical illusion factor. As a result of analyzing the effect of the interaction in the visual image according to the design variables, the influence of the main effect was found to be great in each factor. In the upper-body optical illusion factor, a significant difference was not noted in the two-way interaction between the length and the princess line. However, the influence on three-way interaction among the length, princess line, and silhouette was significant.

• 한국통신학회논문지
• /
• 제34권7C호
• /
• pp.654-662
• /
• 2009

모바일 비디오 스트리밍을 위해 비디오 스트림들을 사용가능한 대역폭에 맞추면서 인코딩을 하기 위해서 시간 적 해상도, 공간적 해상도, 화면 화질의 세 가지 요소를 가지고 조절할 수 있는데, 그 중에서도 양자화 파라미터 (quantization parameter)를 가지고 화변 화질을 조절하는 것이 가장 널리 사용되고 있는 방법이다. 그러나 본 논 문에서는 낮은 대역폭 환경에서는 적응적으로 공간적 해상도를 변경하는 것이 화면 화질이나 에너지 소모량 면에서 더 효율적이라는 것을 보이고, 사용 가능한 대역폭에 대해서 최척의 공간적 해상도를 찾기 위한 모델을 제시 한다. 적응적 공간 해상도 제어 기법은 비디오 서버와 모바일 기기 간의 대역폭이 심하게 변화거나, 모바일 기기가 에너지 소모에 민감한 상황에서 특히 효과적이다. 본 기법은 낮은 비트율 상황에서 기존의 방법에 비해 화질을 약 0.5dB 만큼 개선하고, 에너지 소모를 50% 이상 줄일 수 있다.

• 한국산학기술학회논문지
• /
• 제21권11호
• /
• pp.125-138
• /
• 2020

현재 한국의 전자상거래 시장은 급성장 중이고 특히 온라인 상거래에서는 SNS를 통한 거래가 지속적으로 증가하는 추세입니다. 본 연구는 정보시스템 성공 모델을 적용하고 이를 SERVQUAL의 수정과 결합함으로써 고객의 관점으로 전자상거래 상황에서 SNS 기반 상거래에 대한 서비스 품질 결정 요인의 영향에 대해 조사합니다. 본 논문은 누적 샘플링 기술을 사용하여 진행한 온라인 설문 조사에서 총 216개의 표본을 분석했습니다. 독립변수로 확신성, 공감성, 반응성, 신뢰성, 자각된 유용성 및 고객만족을 사용하였습니다. 종속변수로는 자각된 유용성, 고객만족 그리고 순이익으로 설정하였습니다. SPSS 25 통계 프로그램을 통해 빈도 분석, 요인분석&신뢰도분석, 회귀분석을 진행하였습니다. 이로써 총 11개의 가설에 대한 결과를 도출하였습니다. 결과는 확신성(Assurance), 공감성(Empathy), 반응성(responsiveness) 그리고 신뢰성(Realiability)은 자각된 유용성(Perceived Usefulness)과 고객만족(Customer Satisfaction)에 중요한 영향을 미친다는 것을 보여줍니다. 또한 SNS기반의 상거래에서 자각된 유용성, 고객 만족도 및 순이익 간의 긍정적인 유의미한 관계를 보여주고 있습니다. 이러한 유의미한 결과를 토대로 향후 관련된 후속 연구에 도움이 될 것이라 기대합니다.