• 한국산학기술학회논문지
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• 제13권9호
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• pp.4107-4118
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• 2012

본 연구는 한국 여성근로자의 직업관련 건강상태와 영향요인을 파악하기 위한 서술적 상관관계연구이다. 본 연구자료는 한국산업안전보건공단 한국산업안전보건연구원에서 취업자 근로환경 전국표본조사를 위해 2006년도 시행한 근로환경조사를 바탕으로 20-64세 여성근로자들로부터 얻었다. 한국 여성근로자의 직업관련 신체적 건강상태는 교육수준, 가정내 주수입원 종류, 회사규모, 고용형태, 주당 근로시간, 교대근무여부, 직무요구도 등에서 유의한 차이가 있었다. 심리적 건강상태는 교육수준, 월 평균소득, 가정내 주수입원 종류, 주당 근로시간, 교대근무 여부, 감정노동여부, 직무요구도, 직무자율성, 물리적 위험, 화학적 위험, 근골격계 위험부담요인 등에서 유의한 차이가 있었다. 직업관련 신체적 심리적 건강상태에 영향을 주는 요인을 알아보기 위해 단계적 중회귀분석을 한 결과 신체적 건강상태와 심리적 건강상태에 가장 큰 영향을 주는 요인은 근골격계 부담 이었고 설명력은 각각 6.12%, 2.97% 이었다. 그러므로 근골격계 부담요인 감소를 위한 작업장 환경조성과 체계적인 건강관리 및 보건교육이 필요할 것으로 사료된다.

• Journal of Pharmaceutical Investigation
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• 제32권2호
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• pp.65-72
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• 2002

Recently, stem cell-mediated gene therapy is emerging as a novel therapeutic approach. For the successful gene modification of stem cells, the development of a suitable gene transfer technique needs to be preceded. This review focuses on the various gene transfer techniques based on nonviral and viral vectors, and physical methods. The advantages and disadvantages of each gene transfer method are compared, and the general properties of these vectors are discussed in relation to the gene transfer in stem cell research. This review also highlights the therapeutic application of stem cell-mediated gene therapy. The choice of gene transfer vectors may vary depending on the type of the stem cells and the target of stem cell therapy. Of various gene transfer methods, viral vector-based gene therapy has been emphasized due to the higher transfection efficiency. The current status and up-to-date findings of stem cell-mediated gene therapy are discussed in the viewpoint of the various targets of stem cell therapy such as the modification of stem cell potency, the acceleration of regeneration process and the formation of expressional organization.

• 보건교육건강증진학회지
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• 제33권4호
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• pp.89-100
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• 2016

Objectives: Life style modification leads to decrease health risk and change of health status for person at health risk. This study aimed to suggest essential components and effective strategies for customized health management service to provide individual and risk group in public and private health care organizations. Methods: To systematic review the essential component of health management service, I performed to collect political legislation, research papers, reports, publication and public release for heath management service from 2008 to 2016. Essential components of heath management service were service scope, service design, organizations and applied technology. Results: Service cope was composed of health risk factors, such as smoking, drinking, nutrition, physical activity and weight control. Main strategies were customized health management services, personalized behavior modification programs, evidence-based service protocol, utilization of information and communications technology (ICT), multi-dimension and multi-level approach, and public and private organizations partnership through health policies and health care system. Conclusions: To make the most of the limited resources, it should require a systematic approach that focuses on continuous monitoring and partnership of health management service.

• The Plant Pathology Journal
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• 제30권1호
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• pp.1-9
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• 2014

Acetylation of histone lysine residues occurs in different organisms ranging from yeast to plants and mammals for the regulation of diverse cellular processes. With the identification of enzymes that create or reverse this modification, our understanding on histone acetylation has expanded at an amazing pace during the last two decades. In fungal pathogens of plants, however, the importance of such modification has only just begun to be appreciated in the recent years and there is a dearth of information on how histone acetylation is implicated in fungal pathogenesis. This review covers the current status of research related to histone acetylation in plant pathogenic fungi and considers relevant findings in the interaction between fungal pathogens and host plants. We first describe the families of histone acetyltransferases and deacetylases. Then we provide the cases where histone acetylation was investigated in the context of fungal pathogenesis. Finally, future directions and perspectives in epigenetics of fungal pathogenesis are discussed.

• Journal of Plant Biotechnology
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• 제3권2호
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• pp.67-81
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• 2001

Traditionally, genetic variability is generated by an extensive crossing program, which is complemented by strict selection to identify useful new recombinants. Plant biotechnology offers many opportunities for breeders to solve certain breeding problems at the molecular level. The tissue culture methodology and the genetic modification of economically important monocotyledons have undergone a revolution in the last decade. As the production of transgenic plants is a complex procedure, including the uptake of DNA molecules into the cells, the integration of foreign nucleotide sequences into the host genomic DNA and the expression of new genes in a controlled way, and as there are still many unsolved questions, further development is necessary. The methodology opens up the possibility of introducing novel genes that may induce resistance to diseases and abiotic stresses, allow the modification of dough quality and the dietetic quality of proteins, and increase the levels of micronutrients such as iron, zinc, and vitamins. In the present review, the authors would like to summarise the most important advances in wheat transformation.

• 한국항행학회논문지
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• 제25권3호
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• pp.185-193
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• 2021

항공기의 성능 개선이나 관련 법규의 요건 만족을 위해 항공기 시스템 개조는 필요하다. 이러한 개조를 위해 기술력이나 항공기의 감항성을 위한 설계 검증, 형식 증명에 대한 부가형식증명(STC)의 인증 절차는 적절한 표준이 요구된다. 본 연구는 국내 항공기 개조 현황과 수요를 분석하고 현재의 부가형식증명 절차를 검토하여 그 문제점을 진단한다. 또한 늘어난 항공기의 수명에 대하여 개조기술 및 인증 능력 향상방안을 연구한 결과 개조 조직의 인가와 분야별 전문 엔지니어 자격 임명 그리고 교육 체계 개선이 요구되었고 국내 부가형식증명 절차의 개선을 도출하였다.

• Journal of Nutrition and Health
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• 제42권3호
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• pp.234-245
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• 2009

Nutritional assessment for the elderly can identify health status and morbidity. However, development of Nutritional Risk Index (NRI) remains limited for elderly because of difficulties in understanding physiological mechanism of elderly. This study was performed to analyze and develop Nutritional Risk Index for Korean elderly Women (Geriatric Nutritional Risk Index, GNRI). Based on literature review, factors for NRI were identified and indices were assessed by a cross-sectional survey. The survey involved Korean elderly women (${\geq}$60, n = 94) in Gwangju area, and sociodemographics, lifestyle characteristics, health conditions, dietary intakes based on 24h- recall, anthropometric measures (wt, ht, BMI, waist, hip, WHR, body protein, body fat, abdominal fat, and triceps skinfold thickness), and clinical biochemistry parameters (systolic blood pressure, diastolic blood pressure, cholesterol, HDL-cholesterol, triglyceride, total protein, albumin, prealbumin, hemoglobin, hematocrit, fasting blood glucose, HbAlc, ferritin, Zn, Ca, Na, K, Vit E, Vit $B_{12}$, folate, C-reactive protein) were examined relation to nutritional risk index. Based on literature review and data analyses, three NRIs were categorized (NRI I, NRI II, NRI III) and used for further analysis. NRI I was related to having metabolic syndrome, NRI II was related to serum albumin and body weight, and NRI III was related to food habit and health concerns. Abdominal fat (%) of elderly was correlated with each NRIs. NRI II was correlated with nutritional deficiency and higher tendency of inflammatory response, and NRI III was correlated with nutritional status which tend to be lower on aging (protein, folate, Vit $B_{12}$). NRI can serve as a useful tools in assessing health risk and nutritional status. Some modification of items in NRI and validity study are need to apply to Korean elderly.

• 한국인터넷방송통신학회논문지
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• 제13권2호
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• pp.239-244
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• 2013

건설현장에서 공사 진행 사항을 실시간으로 취득하여 3차원 공간정보와 센서네트웍을 결합한 유비쿼터스 기반 건설현장 관리시스템을 구현함으로써 건설현장에 가서 공사 진척 현황을 확인해야 하는 수고와 시간을 아낄 수 있고 실시간 정보를 PC, 노트북 또는 스마트 폰 등으로 전송하여 공사 관련 담당자나 담당자가 있는 사무실 등에서 수신할 수 있도록 하였다. 특히, 건설현장의 공사 진행 현황은 물론 공사에 영향을 미칠 수 있는 온도, 습도 등의 환경정보 및 GPS 정보를 모바일 스마트 폰으로 제공함으로써 언제 어느 곳에서든지 필요한 정보를 제공받을 수 있을 뿐만 아니라 공사의 진행과 설계변경 등에 도움을 줄 수 있도록 하여 건설현장 실시간 자동관리가 가능할 수 있도록 연구되었다.

• 대한간호학회지
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• 제38권6호
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• pp.866-873
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• 2008

Purpose: The study was done to compare quality of life by gender, and to identify factors which explain quality of life in individuals with coronary artery disease. Methods: For the survey, 91 individuals (53 men and 38 women) agreed to participate in the study. Cardiovascular risk factors, systolic blood pressure, body mass index, total cholesterol, triglyceride, high density lipoprotein-cholesterol, and low density lipoprotein-cholesterol, health behavior as well as quality of life, were measured. Descriptive statistics, t-test, correlation and hierarchical multiple regression with SPSS WIN 12.0 were used to analyze the data. Results: Significant gender differences were found for education, smoking status, chronic disease, perceived health status, and quality of life within sub-dimensions. Hierarchical regression analysis showed gender (men), age, perceived health status, cardiovascular risk scores, and health behaviors together explained 40.2% (adjusted $R^2$) of variance in quality of life. Conclusion: As the factors explaining quality of me in individuals with coronary artery disease have been identified as gender (men), age, perceived health status, and health behaviors, health promotion programs designed for this population should focus on these factors for effective behavioral modification, and consequent improvement in quality of life.

• Journal of Animal Science and Technology
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• 제57권1호
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• pp.1.1-1.11
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• 2015

Background: Due to increased interest in animal welfare, there is now a need for a comprehensive assessment protocol to be used in intensive pig farming systems. There are two current welfare assessment protocols for pigs: Welfare Quality$^{(R)}$ Assessment Protocols (applicable in the Europe Union), that mostly focuses on animal-based measures, and the Swine Welfare Assurance Program (applicable in the United States), that mostly focuses on management- and environment-based measures. In certain cases, however, animal-based measures might not be adequate for properly assessing pig welfare status. Similarly, welfare assessment that relies only on environment- and management-based measures might not represent the actual welfare status of pigs. Therefore, the objective of this paper was to develop a new welfare protocol by integrating animal-, environment-, and management-based measures. The background for selection of certain welfare criteria and modification of the scoring systems from existing welfare assessment protocols are described. Methods: The developed pig welfare assessment protocol consists of 17 criteria that are related to four main principles of welfare (good feeding, good housing, good health, and appropriate behavior). Good feeding, good housing, and good health were assessed using a 3-point scale: 0 (good welfare), 1 (moderate welfare), and 2 (poor welfare). In certain cases, only a 2-point scale was used: 0 (certain condition is present) or 2 (certain condition is absent). Appropriate behavior was assessed by scan sampling of positive and negative social behaviors based on qualitative behavior assessment and human-animal relationship tests. Results: Modification of the body condition score into a 3-point scale revealed pigs with a moderate body condition (score 1). Moreover, additional criteria such as feed quality confirmed that farms had moderate (score 1) or poor feed quality (score 2), especially those farms located in a high relative humidity region. Conclusions: The developed protocol can be utilized to assess welfare status in an intensive pig farming system. Although further improvements are still needed, this study is a first step in developing a pig welfare assessment protocol that combines animal-, environment-, and management-based measures.