• 통합자연과학논문집
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• 제16권1호
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• pp.39-45
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• 2023

P2X receptors are ATP-activated ion channels in the plasma membrane. P2X receptors have a role in a diverse range of disorders, making them a valuable therapeutic target. Hence, the present investigation employed homology modelling of the P2X receptor based on the crystal structure of 5SVJ, 6AH4, 5YVE and 5SVL. Twenty models, using both single- and multiple template-based methods, were developed, and the best model was chosen based on the validation result. We observed that a strategy based on multiple templates provided greater accuracy. Future studies involving binding site and docking analysis can make use of the produced structures.

• Smart Structures and Systems
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• 제20권2호
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• pp.127-137
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• 2017

Identification of damping characteristics is of significant importance for dynamic response analysis and condition assessment of structural systems. Damping is associated with the behavior of the energy dissipation mechanism. Identification of damping ratios based on the sensitivity of dynamic responses and the model updating technique is investigated with numerical and experimental investigations. The effectiveness and performance of using the sensitivity-based model updating method and vibration monitoring data for damping ratios identification are investigated. Numerical studies on a three-dimensional truss bridge model are conducted to verify the effectiveness of the proposed approach. Measurement noise effect and the initial finite element modelling errors are considered. The results demonstrate that the damping ratio identification with the proposed approach is not sensitive to the noise effect but could be affected significantly by the modelling errors. Experimental studies on a steel planar frame structure are conducted. The robustness and performance of the proposed damping identification approach are investigated with real measured vibration data. The results demonstrate that the proposed approach has a decent and reliable performance to identify the damping ratios.

• Structural Engineering and Mechanics
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• 제32권2호
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• pp.251-267
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• 2009

Reinforced concrete (RC) structures consist of two different materials: concrete and steel bar. The stress transfer behaviour between the two materials through bond plays an important role in the load-carrying capacity of RC structures, especially when they subject to lateral load such as blast and seismic load. Therefore, bond and slip between concrete and reinforcement bar will affect the response of RC structures under such loads. However, in most numerical analyses of blast-induced structural responses, the perfect bond between concrete and steel bar is often assumed. The main reason is that it is very difficult to model bond slip in the commercial finite element software, especially in hydrodynamic codes. In the present study, a one-dimensional slide line contact model in LS-DYNA for modeling sliding of rebar along a string of concrete nodes is creatively used to model the bond slip between concrete and steel bars in RC structures. In order to model the bond slip accurately, a new approach to define the parameters of the one-dimensional slide line model from common pullout test data is proposed. Reliability and accuracy of the proposed approach and the one-dimensional slide line in modelling the bond slip between concrete and steel bar are demonstrated through comparison of numerical results and experimental data. A case study is then carried out to investigate the bond slip effect on numerical analysis of blast-induced responses of a RC column. Parametric studies are also conducted to investigate the effect of bond shear modulus, maximum elastic slip strain, and damage curve exponential coefficient on blast-induced response of RC columns. Finally, recommendations are given for modelling the bond slip in numerical analysis of blast-induced responses of RC columns.

• 만화애니메이션 연구
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• 통권6호
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• pp.116-131
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• 2002

Character plays an important role not merely in animation but also in the modern image industry. From this perspective a new academic approach to and an analysis of character seems of much significance. With this in view this study carried out an elucidation of the basic factors and concept of plasticity for the creation of animation character on the basis of animation structural elements. Furthermore, an inquiry was conducted into fundamental requirements and factors of animation characters, human anatomy serving as the basis of forms for animation character modelling, the characteristics and techniques for creating animation cubic character, and then suggested a method of creation. In this process it was revealed that integral cubic character was applied to diverse animations, that character of high density was prerequisite for the creation of creative and effective animations, and that cubic character plasticity played a catalytic role in activation popular sympathy and the character industry.

• 한국방재안전학회논문집
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• 제10권1호
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• pp.1-10
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• 2017

근래에 들어 증가하고 있는 도심지 지반함몰 사고는 사회적 이슈가 되고 있으며 이로 인해 최근 관련 법안이 발의 되었다. 지반함몰은 수많은 원인인자들의 복합적 작용으로 발생하므로 수치해석적 기법의 적용에 한계점이 존재한다. 이로 인해 지반함몰 메커니즘 규명 연구는 주로 모형실험을 이용하여 진행되었다. 선행 연구들은 상하수도관 파열로 인한 지반함몰 모사에 초점이 맞추어져 있으며, 지하수 흐름, 지반 굴착공사 등 다양한 원인에 의해 발생하는 지반함몰에 대한 연구가 부족한 실정이다. 또한 기존 수행된 대부분의 모형실험은 1 g 상태의 모형실험이며, 지반함몰 메커니즘 평가 시 지반의 현장 구속응력을 고려할 수 없다. 따라서 본 논문에서는 모형실험을 이용한 지반함몰 거동 평가에 대한 선행 연구동향들을 고찰하여 보다 다양한 환경 조건을 모사할 수 있는 기법들에 대해 논의하였다. 또한 본 연구에서는 더 신뢰성이 있는 지반함몰 메커니즘 평가 기법으로서 원심모형실험기법을 제시하였다. 마지막으로 본 연구에서는 지반안정성평가에 지반함몰 메커니즘에서 사용한 모형실험 기법을 적용할 것을 제시했다.

• 한국환경복원기술학회지
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• 제2권1호
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• pp.29-37
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• 1999

Land cover classification is an essential basic information in natural environment management; however, land cover classification studies in Korea have not yet been proceeded to a sufficient level. At the present, only a limited number of the precedent studies that only cover definite city area has been conducted. Furthermore, there is almost no research conducted on the land cover classification schemes that could accurately classify the Korea's land cover conditions. This study primarily focuses on the land cover classification scheme which carries the most urgent priority in order to classify and to map out the Korean land cover conditions. In order to develop the most suitable land cover classification scheme, many foreign land cover classification cases and projects that are being carried out were reviewed in depth. The land cover classification scheme this study proposes comprises 3 levels : The first level consists of 7 different classes; the second level consists of 22 different classes; and the third level is made up of 50 classes. The land cover classification map will serve many important roles in natural environment management, such as the conjecture of natural habitats and estimation of oxygen production or carbon dioxide absorption capability of a forest. In water pollution modelling, the land cover classification data can be used to estimate and locate non-point sources of water pollution. If applied to a watershed, modelling it will allow to estimate the total amount of pollution from non-point sources of pollution in the water shed. The land cover classification data will also be good as a barometer data that determines defusion of air pollutants in air pollution modelling.

• 문화기술의 융합
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• 제7권2호
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• pp.367-375
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• 2021

본 연구는 텍스트 마이닝을 이용하여 언택트 연구의 지식구조를 파악하고 연구 방향 정립을 위한 함의를 찾고자 하였다. 2019년부터 2020년 10월까지 발표된 연구 문헌 171편의 서지정보를 네트워크 분석과 토픽 모델링 기법을 사용, 분석하였다. 사용, 서비스, 소비, 영향, 기술 키워드 등의 등장 빈도가 높았고, 등장논문의 수는 코로나19, 기술, 사용, 서비스의 순서였다. 중심성과 구조적 공백 분석 결과 서비스, 사용, 소비, 기술, 온라인 등의 키워드를 중심으로 연구가 이루어졌고, 더 연구가 필요함을 확인하였다. 토픽 모델링으로 코로나19와 사회기술변화, 교육콘텐츠 필요성 및 활용, 사용자 편의 기술 및 서비스, 제품 마케팅 및 판매, 기업의 서비스 디자인, 사용과 소비 영향요인 등 6개 토픽을 추출하였고 토픽을 잇는 키워드는 기술, 서비스, 사용, 소비, 필요, 요인 등이었다. 지식구조 분석은 언택트 연구와 정책 제안에 유용한 정보를 제공할 수 있다. 본 연구의 탐색적 성격을 넘어 양적 축적과 질적 다변화가 필요하다.

• 대한화학회지
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• 제57권1호
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• pp.99-103
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• 2013

The present communication deals with the Pharmacophore modeling, 3D QSAR and docking analysis on series of Pyrimidine derivatives as potential calcium channel blockers. The computational studies showed hydrogen bond donor, hydrogen bond acceptor, and hydrophobic group are important features for calcium channel blocking activity. These studies showed that Pyrimidine scaffold can be utilized for designing of novel calcium channels blockers for CVS disorders.

• 한국터널지하공간학회 논문집
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• 제10권1호
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• pp.91-104
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• 2008

터널의 경우 안정성을 정량적으로 평가하기 위해 안전율 개념이 제안된 바 있다. 이는 역학적 해석의 범주에 한정된 것으로 수리 역학적(hyro-mechanical) 연계해석의 범주에서는 해석 모델링의 복잡성으로 인해 안전율 개념이 적용된 연구는 극히 드문 실정이다. 최근 들어 수리-역학적 연계해석에 관한 연구가 활발히 진행되고 있다. 본 연구에서는 해저 터널의 안전율을 정확히 산정하기 위해 수리-역학적 연계해석 시 유도배수 모델링 방법을 비교 분석하였다. 수치해석 시 터널 내부로 유도배수하는 방법으로는 숏크리트 수리특성을 조절하는 유도배수 방법과 집수정을 이용한 유도배수 방법이 고려되었다. 두 방법의 비교를 위해 암반등급, 숏크리트 두께, 암반 수리특성에 대하여 민감도 분석을 수행하였고, 연구 결과 해저터널의 수리-역학적 연계해석 시 집수정을 이용한 유도배수 방법을 사용하는 것이 터널의 안정성을 검토하는 데에 보다 신뢰성이 높은 것으로 나타났다.

• Journal of Electrical Engineering and Technology
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• 제8권6호
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• pp.1615-1625
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• 2013

Modelling and simulating the wind power intermittent behaviour are the basis of the planning and scheduling studies concerning wind power integration. The wind power outputs are evidently correlated in space and time and bring challenges in characterizing their behaviour. This paper provides a methodology to model and simulate the clustered wind power considering its spatio-temporal correlations using the theory of copula. The sampling approach captures the complex spatio-temporal connections among the wind farms by employing a conditional density function calculated using multidimensional copula function. The empirical study of real wind power measurement shows how the wind power outputs are correlated and how these correlations affect the overall uncertainty of clustered wind power output. The case study validates the simulation technique by comparing the simulated results with the real measurements.