• Title/Summary/Keyword: modeling activity

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Optimization of Processing Conditions for Making a Black Ginger and Design Mixture for Black Ginger Drinks (흑생강 제조 공정 최적화 및 기능성 흑생강 음료 제조)

  • Ban, Young-Ju;Baik, Moo-Yeol;Hahm, Young-Tae;Kim, Hye-Kyung;Kim, Byung-Yong
    • Food Engineering Progress
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    • v.14 no.2
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    • pp.112-117
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    • 2010
  • Black ginger, obtained from steaming and drying process, provides the various functional properties. This study was performed to investigate the optimum processing conditions for black ginger with high content of biologically active substance such as anti-oxidations. Optimum processing conditions such as temperature and time for black ginger was determined by response surface methodology (RSM) with manufacturing process and functionality. The optimum steaming condition was determined 6 hours at 93.2$^{\circ}C$, and 82.7 mg/L DPPH scavenging activities was obtained at this condition. The black ginger drink was made with black ginger extracts, Japanese apricot, and honey. Interaction effects of these ingredients were investigated by modified distance based on design and analyzed by linear, nonlinear regression model, and RSM. The optimization of mixture ratio was made by statistical modeling using DPPH scavenging activities and sensory properties which are the important target constraints in drink. Total flavonoids showed a linear canonical form, while preference and antiradical activity showed a nonlinear canonical form indicating the higher interaction among mixtures. The response trace plot revealed that antiradical activity, sensory properties and total flavonoids were quite sensitive to the drink blending. The optimum formulation of the drink was set at 14.2% of black ginger extracts, 5% of Japanese apricot, and 10.8% honey.

Estimation of Ventilation Rates in Korean Homes Using Time-activity Patterns and Carbon Dioxide (CO2) Concentration (시간활동양상 및 이산화탄소 농도를 이용한 한국 주택 환기량 추정)

  • Park, Jinhyeon;Ryu, Hyeonsu;Heo, Jung;Cho, Mansu;Yang, Wonho
    • Journal of Environmental Health Sciences
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    • v.45 no.1
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    • pp.1-8
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    • 2019
  • Objectives: The purpose of this study was to estimate the ventilation rate of residential homes in Korea through tracer gas methods using indoor and outdoor concentrations of carbon dioxide ($CO_2$) and $CO_2$ generation rates from breathing. Methods: In this study, we calculated the number of occupants in a home by time through data on the average number of people per household from the Korean National Statistical Office and also measured the amount of $CO_2$ generation by breathing to estimate the indoor $CO_2$ generation rate. To estimate the ventilation rate, several factors such as the $CO_2$ generation rate and average volume of residential house provided by the Korean National Statistical Office, indoor $CO_2$ concentrations measured by sensors, and outdoor $CO_2$ concentrations provided by the Korea Meteorological Administration, were applied to a mass balance model for residential indoor environments. Results: The average number of people were 2.53 per household and Koreans spend 61.0% of their day at home. The $CO_2$ generation rate from breathing was $13.9{\pm}5.3L/h$ during sleep and $15.1{\pm}5.7L/h$ in a sedentary state. Indoor and outdoor $CO_2$ concentrations were 849 ppm and 407 ppm, respectively. The ventilation rate in Korean residential houses calculated by the mass balance model were $42.1m^3/h$ and 0.71 air change per hour. Conclusions: The estimated ventilation rate tended to increase with an increase in the number of occupants. Since sensor devices were used to collect data, sustainable data could be collected to estimate the ventilation rate of Korean residential homes, which enables further studies such as on changes in the ventilation rate by season resulting from the activities of occupants. The results of this study could be used as a basis for exposure and risk assessment modeling.

Sustainable Land Use within a Limit of Environmental Carrying Capacity in Metropolitan Area, Korea (지속가능한 발전을 위한 환경용량의 산정과 토지이용형태 연구 - 수도권지역을 중심으로 -)

  • Moon, Tae-Hoon
    • Korean System Dynamics Review
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    • v.8 no.2
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    • pp.51-82
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    • 2007
  • The purpose of this paper is exploring changes in land use pattern when considering environmental carrying capacity. A sustainable development requires a society to define sustainability constraints, environmental carrying capacity. Environmental carrying capacity can be defined as a level of human activity a region can sustain at a desired level of quality of environment. This concept of environmental carrying capacity can be applied to land use to explore sustainable land use pattern. Since land use pattern can affect environment in an important way, exploring sustainable land use pattern within the limit of environmental carrying capacity can suggest useful implications for a sustainable regional management and planning. For this purpose, this paper built the environmental carrying capacity land use model and applied it to the Metropolitan Area, Korea. System dynamics modeling methods was used to build the model. The model developed in this paper consisted of 6sectors; population, housing, industry, land, environment, and traffic sector. The model limits its main focus on the NO2 level as an indicator of quality of environment in Metropolitan Area. Box model was translated into system dynamics model and combined to urban dynamics model to estimate NO2 level, the maximum number of population, industry structure, housing and maximum amount of land use for industrial, housing, and green space that can sustain desirable NO2 level. Metropolitan area was divided into 16 areas and the model was applied to each area. Since NO2 is flowing in and out from each area, model was built to allow this transboundering nature of air pollutants. Based on the model estimation, several policy implications for a sustainable land use pattern was discussed.

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Changes in Serum Biochemical Markers of Bone Cell Activity in Growing Thoroughbred Horses

  • Inoue, Yoshinobu;Asai, Y.;Ohmori, H.;Fujii, H.;Matsui, T.;Yano, H.
    • Asian-Australasian Journal of Animal Sciences
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    • v.19 no.11
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    • pp.1632-1637
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    • 2006
  • We studied the changes in biochemical markers of bone metabolism in growing Thoroughbred horses. Serum osteocalcin (OC), as a marker for bone formation, and carboxy-terminal propeptide of type-I collagen (PICP), as a marker for bone formation, carboxy-terminal telopeptide of type-I collagen (ICTP), as a marker for bone resorption, were determined in nine clinically healthy horses from 3 d to 17 mo of age. The BW and withers height (WH) increased during the study. On the other hand, a rapid reduction in body weight gain (BWG) was observed between 1 mo and 9 mo of age and a rapid reduction in withers height gain was observed between 1 mo and 5 mo of age. The serum markers decreased significantly with increasing age. In particular, dramatic changes in serum markers occurred between 3 d to 1 wk and 5 to 7 mo of age in these horses, which suggests that bone turnover rapidly decreased after birth. On the other hand, the ratio of PICP to ICTP decreased through the experiment. This result suggests that the reduction in bone formation exceeded that of bone resorption. There was a significant correlation between markers and growth parameters, except for the correlation between PICP and BWG on single linear regression analysis. Serum OC and ICTP were affected by the WH in multiple linear regression analysis. These results indicated that the age-related variation in serum biochemical markers of bone metabolism reflected bone growth, but neither BW nor BWG. Therefore, we consider that changes in bone modeling are the major factor affecting the levels of serum biochemical markers by 17 mo of age in horses.

A Study on the Effect of CEO and Eemployee's Intention to Innovation Activity Performances (경영자와 조직구성원의 의지가 혁신활동성과에 미치는 영향에 관한 연구)

  • Kim, Tae Sung;Koo, Il Seob
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.10 no.2
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    • pp.11-16
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    • 2015
  • A lot of factor effects on the enterprise's innovation and business performance, for instance CEO and members intention etc.. Niehoff et al. says, The success factors of innovation enterprise's management lead to members of vision, innovation, innovation activities and support for an aggressive attitude of the enterprise members. However, today's products consumers wanted diverse and complex needs. CEO and members of the enterprise has been the diversity effort. The increase cost savings as well as in the profit improve factors that enterprise's participated a education and training, Subgroup activities, process quality, eliminate waste, improve yields, lead time reduction, process capability increasing, ets. This paper is a report of an empirical survey performed to 277 small and medium-sized enterprise in the korea. Cronbach's alpha coefficient is employed to analyze the reliability of the data. The effect analysis of each group is performed by the SEM(structural equation model). We use the SPSS' Amos program to analyze the equation modeling and test the hypotheses of the model.

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p-Coumaric Acid Potently Down-regulates Zebrafish Embryo Pigmentation: Comparison of in vivo Assay and Computational Molecular Modeling with Phenylthiourea

  • Kim, Dong-Chan;Kim, Seonlin;Hwang, Kyu-Seok;Kim, Cheol-Hee
    • Biomedical Science Letters
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    • v.23 no.1
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    • pp.8-16
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    • 2017
  • p-Coumaric acid is an organic compound that is a hydroxyl derivative of cinnamic acid. Due to its multiple biological activities p-coumaric acid has been widely studied in biochemical and cellular systems and is also considered as a useful therapeutic candidate for various neuronal diseases. However, the efficacy of p-coumaric acid on zebrafish developmental regulation has not been fully explored. In this study, therefore, we first investigated the action mechanism of the p-coumaric acid on the zebrafish development in a whole-organism model. p-Coumaric acid treated group significantly inhibited the pigmentation of the developing zebrafish embryos compared with control embryos without any severe side effects. In addition, p-coumaric acid down-regulated more effectively in a lower concentration than the well-known zebrafish's melanogenic inhibitor, phenylthiourea. We also compared the molecular docking property of p-coumaric acid with phenylthiourea on the tyrosinase's kojic acid binding site, which is the key enzyme of zebrafish embryo pigmentation. Interestingly, p-coumaric acid interacted with higher numbers of the amino acid residues and exhibited a tight binding affinity to the enzyme than phenylthiourea. Taken all together, these results strongly suggest that p-coumaric acid inhibits the activity of tyrosinase, consequently down-regulating zebrafish embryo pigmentation, and might play an important role in the reduction of dermal pigmentation. Thus, p-coumaric acid can be an effective and non-toxic ingredient for anti-melanogenesis functional materials.

A Child's Informal Knowledge of Multiplication ((두 자리 수)${\times}$(두 자리 수) 해결과정에서 나타나는 아동의 비형식적인 지식에 관한 사례연구)

  • Jeon, Hyung-Og;Lee, Kyung-Hwa
    • Journal of Educational Research in Mathematics
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    • v.18 no.4
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    • pp.483-497
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    • 2008
  • This study investigated what kind of informal knowledge is emergent and what role informal knowledge play in process of solving 2-digit by 2-digit multiplication task. The data come from 4 times interviews with a 3th grade student who had not yet received regular school education regarding 2-digit by 2-digit multiplication. And the data involves the student's activity paper, the characteristics of action and the clue of thinking process. Findings from these interviews clarify the child's informal knowledge to modeling strategy, doubling strategy, distributive property, associative property. The child formed informal knowledge to justify and modify her conjecture of the algorithm.

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Analysis of Engineering Students' Characteristics in Design Problem Solving (설계 문제의 해결 과정에서 나타나는 공과대학생의 문제해결 특성 분석)

  • Rho, Tae-Cheon;Kim, Young-Jong;Kim, Tae-Hoon
    • Journal of Engineering Education Research
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    • v.9 no.4
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    • pp.46-62
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    • 2006
  • The purpose of this study is to identify characteristics which are related with design problem solving. For this, an effective problem solver and an ineffective problem solver have been compared and analyzed in terms of the process of design problem solving with a population of students who are enrolled in College of Engineering. This study can be concluded as follows. First, the process of design problem solving was performed in non-linear form and it was varied depending on individuals. Second, the results of problem solving could be varied according to the qualitative level of performance in each stage rather than according to the differences of consumption time by each stage. Third, the main activities in process of design problem solving were identifying a design brief, identifying requirements, exploring a problem solution, and idea modeling. Fourth, the making activities took place most frequently and the longest time in the entire process, meanwhile exploring a problem solution was related to the results of design problem solving.

The Causal Relationship of Adolescent's Family Conflicts, Self-concept, and School Adjustment as Health Protection Behavior (청소년이 인지하는 가족내 갈등과 건강보호행동으로서의 자아개념, 학교적응간의 인과관계분석)

  • Park Jae-San;Moon Jae-Woo
    • Korean Journal of Health Education and Promotion
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    • v.23 no.2
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    • pp.91-107
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    • 2006
  • Objectives: The school adjustment problems of the adolescence groups become more aggravated and are on the increase. The objective of this study is to identify the causal relationship of intra-family conflicts, self-concept and school adjustment as health protection behavior. Methods: The study setting is the adolescence groups. Data were collected by self-administered questionnaires from the middle and high school students in Seoul. The study sample consisted of 268 students. Structural Equation Modeling(SEM) analysis was conducted to find the causal relationship of intra-family conflicts, self-concept and school adjustment. Results: This study shows that firstly, the total effects of intra-family conflicts have a negative effect on self-concept(path coefficients=-0.080) and school adjustment(path coefficients=-0.107). And the self-concept factor as an intervening variable are affecting positively on school adjustment(path coefficients=0.411). Secondly, the economic conflicts, personaliy conflicts and social activity conflicts of father and mother among various family conflicts are more highly affecting on self-concept and school adjustment(p<0.01) Conclusions: These results imply that first, communication between parents and students is essential to solve the problems of school adjustment. Especially economic conflicts should be solved to improve the self-concept and school adjustment. second, a variety of programs are available for schools to employ in an effort to provide interventions for students who demonstrate school adjustment. Finally, it is necessary for family, school and all the society members to comprehensively cooperate to solve family conflicts and school adjustment.

Dose modeling and its Application of Ir-192 for substitution of Ralstron Brachytherapy source (Ralstron 선원대체형 Iridium-192 선원의 선량모델링과 응용)

  • 김옥배;최태진;김진희;이호준;박정호;김성규;조운갑;한현수
    • Progress in Medical Physics
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    • v.11 no.2
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    • pp.131-139
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    • 2000
  • We designed high dose rate Ir-192 source which was prepared for substitute the Co-60 source in Ralstron unit (Simatsu, Japan) which is supplied for cervical cancer treatment. The source dimension is 1.5 mm in a diameter and 1.5mm thickness of cylinder and encapsulated with 3 mm diameter of stainless steel(SUS316L) to substituted for the Co-60 source size. The Ir-192 source was prepared the dose model for tissue dose computation through the experimental determination of apparent activity and applied the empirical tissue correction factors extended to 20cm distance. The tissue dose model was applied the 4.69 R/cm-mCi-hr gamma constant and the ratio of energy absorption coefficient of water to that of air showed 1.112 include filteration of the self-absorptions. In this experiments, we prepared the dose computation software to clinical usefulness.

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