• Title/Summary/Keyword: missing mechanism

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A review of pathophysiological mechanism of Bisphosphonate-related osteonecrosis of the jaw (임상가를 위한 특집 1 - 비스포스포네이트 관련 골괴사의 병태생리학적 기전에 대한 검토)

  • Kwon, Tae-Geon
    • The Journal of the Korean dental association
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    • v.52 no.4
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    • pp.192-202
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    • 2014
  • Bisphosphonate(BP) significantly influence the hone remodeling process. Increasing number of patients with osteoporosis and metastatic bone disease need high dose or long term bisphosphonate therapy. Major adverse effect is jaw bone necrosis and now the bisphosphonate-related necrosis of the jaw(BRONJ) is the major concern of dental practitioner. This study intended to perform the review of the current understandings concerning the pathophysiology of BRONJ. Even though pathophysiological mechanism of BRONJ is not clearly elucidated but now suggested as largely two different concepts; so-called "inside-out" or "outside-in" theory. Inside-out theory emphasize the osteonecrosis of the jaw is the initial major event and subsequent infection and inflammation is the second event that accompanies bone exposure and death of overlying mucosa. However, in "outside-in" theory, infection or inflammation initiated by traumatized oral epithelium is the major event of BRONJ. Both theory would be partially explain BRONJ. Recent research reveals the immune modulating effect and influence of microcrack accumulation by BP. These findings and those of others might explain the missing part of outside-in theory.

Fault Detection for thyristors of Power Converter Module in Control Rod Control System (원자로 제어봉구동장치 제어시스템의 전력변환기 사이리스터 고장 검출)

  • Kim, Choon-Kyung;Cheon, Jong-Min;Lee, Jong-Moo;Jung, Soon-Hyun;Kwon, Soon-Man
    • Proceedings of the KIEE Conference
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    • 2003.11c
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    • pp.559-562
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    • 2003
  • In this paper, we introduce a new method detecting thyristor faults of the power converter module in Control Rod Control System. When we control the currents in each coil of Control Rod Drive Mechanism by using the current control method, the current value can follow the current reference despite the faults like the missing phase or the diode acting. Comparing the fault current values with the normal current values, the bad transient characteristics of the abnormal current can make the operations of control rods incorrect. In this case, the information from the current trends cannot be enough to detect the fault occurrence in thyristors. Instead of the coil currents, the state of thyristors can be watched by measuring the coil voltages. In the existing system of Westinghouse type, the ripple detector takes charge of this task. But this detector has some shortcomings in the point of time for fault detection, we come to devise a new fault detection method solving the problems which belong to the ripple detector.

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The Effect of Academic Stress on Suicidal Impulse in Adolescence : Mediating Roles of Parent and Peer Attachment (학업스트레스가 청소년의 자살충동에 미치는 영향 : 부모와 친구에 대한 애착의 매개효과)

  • Moon, Kyoung-Suk
    • Korean Journal of Child Studies
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    • v.27 no.5
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    • pp.143-157
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    • 2006
  • This study examined the mediating roles of parent and peer attachment in the relationship between academic stress and suicidal impulse among Korean adolescents. The 2959 ninth grade students in this study were selected from among 3211 students(excluding missing cases) who participated in the Korean Youth Panel Study. Following Baron & Kenny's(1986) suggestion, the mediator model was employed to analyze parent and peer attachment. Results showed that academic stress had a significant relationship with adolescent's suicidal impulse. Parent attachment acted as a partial mediator between academic stress and suicidal impulse; that is parent attachment provided a protective mechanism minimizing the direct effects of academic stress. However, peer attachment had no significant relationship with academic stress.

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Progressive Collapse-Resistant Rotational Capacity Evaluation of WUF-W Connection by Fracture Index Analysis (파괴지수분석에 의한 WUF-W 접합부의 연쇄붕괴저항 회전능력평가)

  • Kim, Seonwoong
    • Journal of the Earthquake Engineering Society of Korea
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    • v.22 no.6
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    • pp.353-360
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    • 2018
  • This paper is to investigate the micro-behavior of the double-span beams with WUF-W seismic connection under combined axial tension and moment and to propose the rational rotational capacity of it for progressive collapse-resistant analysis and design addressing the stress and strain transfer mechanism. To this end, the behavior of the double-span beams under the column missing event is first investigated using the advanced nonlinear finite element analysis. The characteristics of fracture indices of double-span beams with WUF-W connection under combined axial tension and flexural moment are addressed and then proposed the rational rotational capacity as the basic datum for the progressive collapse-resistant design and analysis. The distribution of fracture indices related to stress and strain for the double-span beams is investigated based on a material and geometric nonlinear finite element analysis. Furthermore, the micro-behavior for earthquake and progressive collapse is explicitly different.

Gene Expression Profiling at Early Stage of Head Regeneration in the Earthworm(Perionyx excavatus) using Expressed Sequence Tags

  • Cho, Sung-Jin;Lee, Myung-Sik;Eunsik Tak;Lee, Jong-Ae;Park, Bum-Joon;Cho, Hyun-Ju;Moon, Joo-Sik;Park, Soon-Cheol
    • Proceedings of the Korean Society of Sericultural Science Conference
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    • 2003.10a
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    • pp.143-143
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    • 2003
  • Among all animal species, a few have the remarkable capacity to regenerate a missing part of their body after amputation. The early process of epimorphic regeneration in which dedifferentiation and cell proliferation are involved, provides a useful model to investigate the mechanism of normal development as well as differentiation. To better understand early stage of head regeneration, we have generated 5'-end sequence of 1,592 expressed sequence tags (ESTs) from cDNA library of regenerating tissue. (omitted)

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A Harmony in Language and Music (언어와 음악의 상관관계 고찰을 위한 연구)

  • 이재강
    • Lingua Humanitatis
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    • v.2 no.1
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    • pp.287-301
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    • 2002
  • Either in music or in language, sound plays its role by taking up the fixed multi-spaces in one's consciousness. Music space differs from auditory space whose aim Is to perceive the positions and identities of the outer things. While auditory space is based on the interests of the outer things, music space is based on the indifference. We discuss the notion of space because it is where symbols reside. Categorial perception about the phonemic restoration describes the ability of a listener how to use his own intelligence to acknowledge and fill the missing points; however, musical perception can be explained as a positive regression to avoid colloquial logic and danger of segmentation in the course of auditory experience and phonation acquisition by an infant. About the question on the difference of the listening to the language sound and other sound, auditory mechanism proceeds language sound the same as other types of sound. But there are another theories which claim that brain proceeds the farmer differently from the latter. The function of music has not been discovered as clear as that of language; music has much more meanings in comparison with language.

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Mechanism of Growth Hormone Action : Recent Developments - A Review

  • Sodhi, R.;Rajput, Y.S.
    • Asian-Australasian Journal of Animal Sciences
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    • v.14 no.12
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    • pp.1785-1793
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    • 2001
  • The interaction of growth hormone with it's receptor results in dimerization of receptor, a feature known in action of certain cytokines. The interaction results in generation of number of signalling molecules. The involvement of Janus kinases, mitogen activated kinases, signal transduction and activator of transcription proteins, insulin like substrate, phosphatidylinositol 3-kinase, phospholipase C, protein kinase C is almost established in growth hormone action. There are still many missing links in explaining diversified activities of growth hormone. Amino acid sequence data for growth hormones and growth hormone receptors from a number of species have proved useful in understanding species specific effects of growth hormone. Complete understanding of growth hormone action can have implications in designing drugs for obtaining desired effects of growth hormone.

Development of GPS Tracking System for Container using Smart Tag (Smart Tag를 이용한 컨테이너의 GPS 위치 추적 시스템 개발)

  • Kim, Dong-Wan;Park, Jee-Ho
    • The Transactions of the Korean Institute of Electrical Engineers P
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    • v.55 no.4
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    • pp.176-182
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    • 2006
  • In this paper, we explore a novel transportation container in the marine terminals. The container includes Smart Tag embedded with radio frequency(RF) chips, which is used to access information about productions and possibly incorporated with GPS systems for integrated managements of them. The proposed mechanism is valuable for decreasing cost, increasing satisfaction of customers, and preventing economic loss due to production missing, thus increase of economic efficiency is highly anticipated. Consequently, accurate and proficient management is considerably accomplished in overall procedures of inventory and currency by means of the proposed systems.

A longitudinal data analysis for child academic achievement with Korea welfare panel study data (경시적 자료를 이용한 아동 학업성취도 분석)

  • Lee, Naeun;Huh, Jib
    • Journal of the Korean Data and Information Science Society
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    • v.28 no.1
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    • pp.1-10
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    • 2017
  • Longitudinal data of Korean child academic achievement have been used to find the significant exploratory variables under the assumption of independent repeated measured data. Using the exploratory variables in previous research works, we analyze the linear mixed model incorporating the fixed and random effects for child academic achievement to detect the significant exploratory variables. Korea welfare panel study data observed three times between 2006 and 2012 by additional survey for children. The child academic achievement is evaluated by the sum of academic achievements of Korean, English and Mathematics. We also investigate the multicollinearity and the missing mechanism and select some popular correlation matrices to analyze the linear mixed model.

AKA-PLA: Enhanced AKA Based on Physical Layer Authentication

  • Yang, Jing;Ji, Xinsheng;Huang, Kaizhi;Yi, Ming;Chen, Yajun
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.11 no.7
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    • pp.3747-3765
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    • 2017
  • Existing authentication mechanisms in cellular mobile communication networks are realized in the upper layer by employing cryptographic techniques. Authentication data are broadcasted over the air in plaintext, enabling attackers to completely eavesdrop on the authentication and get some information about the shared secret key between legitimate nodes. Therefore, reusing the same secret key to authenticate several times results in the secret key's information leakage and high attacking rate. In this paper, we consider the most representative authentication mechanism, Authentication and Key Agreement (AKA), in cellular communication networks and propose an enhanced AKA scheme based on Physical Layer Authentication (AKA-PLA). Authentication responses generated by AKA are no longer transmitted in plaintext but masked by wireless channel characteristics, which are not available to adversaries, to generate physical layer authentication responses by a fault-tolerant hash method. The authenticator sets the threshold according to the authentication requirement and channel condition, further verifies the identity of the requester based on the matching result of the physical layer authentication responses. The performance analyses show that the proposed scheme can achieve lower false alarm rate and missing rate, which are a pair of contradictions, than traditional AKA. Besides, it is well compatible with AKA.