• Archives of Pharmacal Research
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• 제22권6호
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• pp.549-553
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• 1999

The antipruritic effect of DA-5018m a capsaicin derivative, was examined in mice. Male ICR mice were topically pretreated with Zostrix-HP (0.075% capsaicin cream), 0.1%, 0.3% DA-5018 cream or cream base (control) twice daily for 4 days. One hour after the last application, itch was induced either by compound 48/80 ($50{\mu}g$, s.c.) or leukotriene B4 (0.03 nmol, i.d.) injection into the rostral back of the animals, and the number of scratches made by the animals at the injection site was counted for 60 min post-injection. DA-5018 cream (both 0.1 and 0.3%) significantly inhibited compound 48/80-induced scratching when compared with the cream base control (p<0.01), which Zostrix-HP showed minimal inhibition of the scratching behavior. In leukotriene B4-induced itch model, Zostrix-HP and 0.3% DA-5018 cram significantly inhibited the scratching during the first 10-min period (p<0.01). The results suggest that DA-5018 cream can be used as an antipruritic agent and warrant clinical evaluation.

• Restorative Dentistry and Endodontics
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• 제45권3호
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• pp.27.1-27.9
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• 2020

Apical surgery for a mandibular molar is still challenging for many reasons. This report describes the applications of computer-guided cortical 'bone-window technique' using piezoelectric saws that prevented any nerve damage in performing endodontic microsurgery of a mandibular molar. A 49-year-old woman presented with gumboil on tooth #36 (previously endodontically treated tooth) and was diagnosed with chronic apical abscess. Periapical lesions were confirmed using cone-beam computed tomography (CBCT). Endodontic microsurgery for the mesial and distal roots of tooth #36 was planned. Following the transfer of data of the CBCT images and the scanned cast to an implant surgical planning program, data from both devices were merged. A surgical stent was designed, on the superimposed three-dimensional model, to guide the preparation of a cortical window on the buccal side of tooth #36. Endodontic microsurgery was performed with a printed surgical template. Minimal osteotomy was required and preservation of the buccal cortical plate rendered this endodontic surgery less traumatic. No postoperative complications such as mental nerve damage were reported. Window technique guided by a computer-aided design/computer-aided manufacture based surgical template can be considerably useful in endodontic microsurgery in complicated cases.

• 한국안전학회지
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• 제26권4호
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• pp.87-95
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• 2011

The urgent VAI(Vital Area Identification) method development is required since 'The Act of Physical Protection and Radiological Emergency' that is established in 2003 requires an evaluation of physical threats in nuclear facilities and an establishment of physical protection in Korea. The KAERI(Korea Atomic Energy Research Institute) has developed the VAI methodology and VAI software called as VIPEX(Vital area Identification Package EXpert) for identifying the vital areas. This study is to demonstrate the applicability of KAERI's VAI methodology to a hypothetical facility, and to identify the importance of information of cable and piping runs when identifying the vital areas. It is necessarily needed to consider cable and piping runs to determine the accurate and realistic TEPS(Top Event Prevention Set). If the information of cable and piping runs of a nuclear power plant is not considered when determining the TEPSs, it is absolutely impossible to acquire the complete TEPSs, and the results could be distorted by missing it. The VIPEX and FTREX(Fault Tree Reliability Evaluation eXpert) properly calculate MCSs and TEPSs using the fault tree model, and provide the most cost-effective method to save the VAI and physical protection costs.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1993년도 하계학술대회 논문집 B
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• pp.929-931
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• 1993

The design sensitivity analysis based on the finite element method is presented for the eddy current problem with a voltage source. Since, in this problem, the complex variable is used as the state variable, new approach to the sensitivity calculation for the complex variable system is required. Its result is applied to the design of the rotor slot shape of squirrel cage induction motor. As a analysis model, only one slot pitch of rotor is analyzed by using a Periodic boundary condition. The use of this minimal modelling method leads to much saving of calculation time. The design objective is to obtain the desired slip-torque characteristic. Because the shape of rotor slot has much influence on the slip torque characteristic, the design variables are taken on the interface shape between rotor core and rotor bar. The initial shape of rotor slot is the trapezoidal type with rounding corners. The obtained final shape is quite similar to the double squirrel cage type.

• 한국물환경학회지
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• 제29권6호
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• pp.730-738
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• 2013

In recent years, low impact development (LID) has emerged as an effective approach to control stormwater in an urban area, and watershed and stormwater managers need modeling tools to evaluate alternative plans for controlling stormwater. This study illustrates how to design and evaluate the effect of non-point pollutant management using SUSTAIN which is developed by USEPA. SUSTAIN can provide evaluating, selecting, and placing LID facilities in an urban catchment based on user-defined cost-effectiveness criteria. Also, this paper suggests a minimal methodology for estimating model parameters for modeling an ungauged urban catchment to reflect the situation of typical Korean urban interested catchments which are usually ungauged. In addition, the optimal length of various LID facilities and the optimal number of units in our test catchment are estimated.

• 한국소음진동공학회논문집
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• 제21권7호
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• pp.622-628
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• 2011

The purpose of this study was to analyze the vibro-acoustic characteristics of a stiffened rectangular plate at high frequencies. The stiffeners attached along the plate surface were assumed to have rotational and translational stiffness and inertia. The harmonic response of the stiffened plate were predicted and compared using the Rayleigh-Ritz method with two different trial functions - polynomial and beam functions. The variation of the spatially averaged mean square velocity and the modal characteristics with the number of stiffeners were obtained. The use of the beam function ensured fast convergence which was essential for analyzing the high frequency vibration responses. Using the calculated modal characteristics and the Rayleigh-integral, the radiated sound power was predicted, and the effects of stiffeners were investigated. The proposed model can be applied to study optimal layout of stiffeners for minimal noise generation of the stiffened structures.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2013년도 추계학술대회 논문집
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• pp.543-548
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• 2013

이 논문은 세탁기의 진동제어를 위한 MR 댐퍼의 설계과정을 제시한다. 이 연구에서는 MR 댐퍼의 작은 크기와 함께 높은 댐핑력과 저전력을 소비하도록 설계되었다. MR 댐퍼는 전단모드를 사용하도록 제안되었고 빙햄모델을 이용하여 최설설계를 진행하였다. 이 과정에서 멀티코일이 댐핑력을 높이기 위해 적용되었고 최적화된 구조를 찾아내기 위하여 APDL을 이용하여 최적설계가 수행되었다. 이 후 최적의 수치 값들을 통해 제작하여 실험을 수행하였다. 이 때 슬라이딩모드 제어기를 적용하여 시뮬레이션과 제어실험을 모두 수행하였다. 실험의 결과로부터 MR 댐퍼가 세탁기의 진동제어를 위한 요구 댐핑력을 만족시켜줌을 확인하였다.

• 경영정보학연구
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• 제5권2호
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• pp.151-168
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• 2003

A knowledge portal is an integrated gateway for accessing relevant knowledge, collaborating and communicating with other users, and also linking internal applications which is becoming crucial in the age of information abundance. Research and development is a typical knowledge-intensive activity. However, knowledge management support in R&D has been minimal in most research organizations. In this paper, a knowledge portal is designed to support team-based researches in science and technology for searching and browsing knowledge, and also communicating with other team members, coordinating research project and collaborating with other researchers. Automating knowledge acquisition from various knowledge sources, knowledge categorization by applying text categorization method, and knowledge recommendation can help to relieve management effort and increase the efficiency of knowledge management processes. A prototype system based on the suggested model is also presented.

• 한국정보과학회논문지:컴퓨팅의 실제 및 레터
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• 제6권1호
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• pp.36-44
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• 2000

본 논문은 고속통신망을 통하여 사용자 개입을 허용하는 멀티미디어 프리젠테이션과 멀티미디어 응용에 포함된 다양한 미디어의 저작을 동시에 수행할 수 있는 도구의 개발에 관한 것이다. 도구 개발을 위해 실시간 동기식 멀티미디어 프리젠테이션을 지원하기 위해 동적 버퍼링 기법, 송수신 시스템간의 데이타 전송률을 동기화를 위해 버퍼 관리 기법과 QoS 파라메터를 기반으로 한 적응형 전송 알고리즘을 적용하였다. 또한, TRSG 모델을 이용하여 사용자가 프리젠테이션 도중에 참여할 수 있도록 하였다. 마지막으로 제안된 도구가 QoS 유지 및 동기화에 영향을 미치는 요소들을 계속적으로 모니터링하여 멀티미디어 프리젠테이션의 수행 상태를 지속적으로 제어하는 이벤트 감시 스레드 기법을 적용하여 연속적인 출력보장과 최소한의 QoS를 지원할 수 있도록 하였다.

• Steel and Composite Structures
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• 제33권1호
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• pp.1-18
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• 2019

In the present study, the behavior of steel plate shear walls (SPSW) with variable column flexural stiffness is experimentally and numerically investigated. Altogether six one-bay one-story specimens, three moment resisting frames (MRFs) and three SPSWs, were designed, fabricated and tested. Column flexural stiffness of the first specimen pair (one MRF and one SPSW) corresponded to the value required by the design codes, while for the second and third pair it was reduced by 18% and 36%, respectively. The quasi-static cyclic test result indicate that SPSW with reduced column flexural stiffness have satisfactory performance up to 4% story drift ratio, allow development of the tension field over the entire infill panel, and cause negligible column "pull-in" deformation which indicates that prescribed minimal column flexural stiffness value, according to AISC 341-10, might be conservative. In addition, finite element (FE) pushover simulations using shell elements were developed. Such FE models can predict SPSW cyclic behavior reasonably well and can be used to conduct numerical parametric analyses. It should be mentioned that these FE models were not able to reproduce column "pull-in" deformation indicating the need for further development of FE simulations with cyclic load introduction which will be part of another paper.