• Title/Summary/Keyword: minimal damage

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Effect of Liver Damage by Combined Administration of Ethanol and Xylene in Rats (흰쥐에게 Ethanol과 Xylene 병행 투여시 간손상에 미치는 영향)

  • Yoon, In-Sook;Lee, Hye-Ja
    • The Journal of the Korea Contents Association
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    • v.10 no.7
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    • pp.259-267
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    • 2010
  • To evaluate an effect of liver damage on ethanol and xylene exposure, experiments on normal male rats of the S-D strain were performed in 4 groups. The biochemical results suggest that the ethanol group had significantly higher levels of AST, ALT, LDH and also, the xylene group had notably higher levels of AST, ALT, LDH along with MMHPA than those of the control groups. The levels of AST, ALT and LDH in the ethanol+xylene group were drastically higher than those in the control, ethanol and xylene groups. But, there were significantly lower ALP levels in the xylene and ethanol+xylene groups than both the control and ethanol groups. The histological features of rat livers treated with alcohol, or xylene proved to be normal. But the rat livers treated with ethanol+xylene showed mild to moderate necrosis and inflammation as well as minimal fatty changes. The results in this experiment suggest that liver functions decreased when medicated together with xylene and ethanol rather than solely with xylene.

Optimal Life Cycle Cost Design of a Bridge (교량의 생애주기비용 최적설계)

  • Park, Jang-Ho;Shin, Yung-Seok
    • Journal of the Korean Society of Safety
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    • v.25 no.6
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    • pp.115-122
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    • 2010
  • The importance of the life cycle cost (LCC) analysis for bridges has been recognized over the last decade. However, it is difficult to predict LCC precisely since the costs occurring throughout the service life of the bridge depend on various parameters such as design, construction, maintenance, and environmental conditions. This paper presents a methodology for the optimal life cycle cost design of a bridge. Total LCC for the service life is calculated as the sum of initial cost, damage cost, maintenance cost, repair and rehabilitation cost, user cost, and disposal cost. The optimization method is applied to design of a bridge structure with minimal cost, in which the objective function is set to LCC and constraints are formulated on the basis of Korean Bridge Design Code. Initial cost is calculated based on standard costs of the Korea Construction Price Index and damage cost on damage probabilities to consider the uncertainty of load and resistance. Repair and rehabilitation cost is determined using load carrying capacity curves and user cost includes traffic operation costs and time delay costs. The optimal life cycle cost design of a bridge is performed and the effects of parameters are investigated.

Analysis of Microclimate Responses and High-temperature Injury in Ginseng as Affected by Shading (인삼 차광자재별 미기상 및 고온피해 발생 비교 분석)

  • Jang, In Bae;Moon, Ji Won;Yu, Jin;Jang, In Bok;Suh, Su Jeoung;Chun, Chang Hoo
    • Korean Journal of Medicinal Crop Science
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    • v.27 no.4
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    • pp.278-283
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    • 2019
  • Background: High temperature damage in ginseng is influenced by shading materials related not only to temperature, but also to light intensity and light quality. To address, this green-colored khaki shading sheet is widely used. As they are recently, developed, there is limited research information about their attributes and use. Methods and Results: The four-layered shading net (FLSN), blue-colored shading sheet (BCSS), aluminum-coated shading board (ACSB), and green-colored shading sheet (GCSS) were installed in the wooden A type of sun-block facilities. Two layered black, shading net was additionally used to cover the facilities since the beginning of June. The average temperature at the facility where different shades were tested was in the order of BCSS ($28.9^{\circ}C$) > FLSN ($27.7^{\circ}C$) > GCSS ($27.6^{\circ}C$) > ACSB ($27.1^{\circ}C$). However, high temperature injury rates were in order: FLSN > ACSB > GCSS > BCSS. Root weight vaired and was in the order: ACSB > GCSS > BCSS > FLSN. Conclusions: High temperature damage is possible not only because of temperature increase, but also due to various environmental light factors. Ginseng high temperature injury was minimal when BCSS or GCSS were used by difference of light quality. Although the root weight was higher in ACSB, it could be vulnerable to high temperature damage. Therefore, we propose using GCSS for ginseng shading.

The effects of physical decontamination methods on zirconia implant surfaces: a systematic review

  • Tan, Nathan Chiang Ping;Khan, Ahsen;Antunes, Elsa;Miller, Catherine M;Sharma, Dileep
    • Journal of Periodontal and Implant Science
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    • v.51 no.5
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    • pp.298-315
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    • 2021
  • Purpose: Peri-implantitis therapy and implant maintenance are fundamental practices to enhance the longevity of zirconia implants. However, the use of physical decontamination methods, including hand instruments, polishing devices, ultrasonic scalers, and laser systems, might damage the implant surfaces. The aim of this systematic review was to evaluate the effects of physical decontamination methods on zirconia implant surfaces. Methods: A systematic search was conducted using 5 electronic databases: Ovid MEDLINE, PubMed, Scopus, Web of Science, and Cochrane. Hand searching of the OpenGrey database, reference lists, and 6 selected dental journals was also performed to identify relevant studies satisfying the eligibility criteria. Results: Overall, 1049 unique studies were identified, of which 11 studies were deemed suitable for final review. Air-abrasive devices with glycine powder, prophylaxis cups, and ultrasonic scalers with non-metal tips were found to cause minimal to no damage to implantgrade zirconia surfaces. However, hand instruments and ultrasonic scalers with metal tips have the potential to cause major damage to zirconia surfaces. In terms of laser systems, diode lasers appear to be the most promising, as no surface alterations were reported following their use. Conclusion: Air-abrasive devices and prophylaxis cups are safe for zirconia implant decontamination due to preservation of the implant surface integrity. In contrast, hand instruments and ultrasonic scalers with metal tips should be used with caution. Recommendations for the use of laser systems could not be fully established due to significant heterogeneity among included studies, but diode lasers may be the best-suited system. Further research-specifically, randomised controlled trials-would further confirm the effects of physical decontamination methods in a clinical setting.

Fragility-based performance evaluation of mid-rise reinforced concrete frames in near field and far field earthquakes

  • Ansari, Mokhtar;Safiey, Amir;Abbasi, Mehdi
    • Structural Engineering and Mechanics
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    • v.76 no.6
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    • pp.751-763
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    • 2020
  • Available records of recent earthquakes show that near-field earthquakes have different characteristics than far-field earthquakes. In general, most of these unique characteristics of near-fault records can be attributed to their forward directivity. This phenomenon causes the records of ground motion normal to the fault to entail pulses with long periods in the velocity time history. The energy of the earthquake is almost accumulated in these pulses causing large displacements and, accordingly, severe damages in the building. Damage to structures caused by past earthquakes raises the need to assess the chance of future earthquake damage. There are a variety of methods to evaluate building seismic vulnerabilities with different computational cost and accuracy. In the meantime, fragility curves, which defines the possibility of structural damage as a function of ground motion characteristics and design parameters, are more common. These curves express the percentage of probability that the structural response will exceed the allowable performance limit at different seismic intensities. This study aims to obtain the fragility curve for low- and mid-rise structures of reinforced concrete moment frames by incremental dynamic analysis (IDA). These frames were exposed to an ensemble of 18 ground motions (nine records near-faults and nine records far-faults). Finally, after the analysis, their fragility curves are obtained using the limit states provided by HAZUS-MH 2.1. The result shows the near-fault earthquakes can drastically influence the fragility curves of the 6-story building while it has a minimal impact on those of the 3-story building.

Seismic analysis and performance for stone pagoda structure under Gyeongju earthquake in Korea

  • Kim, Ho-Soo;Kim, Dong-Kwan;Jeon, Geon-Woo
    • Earthquakes and Structures
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    • v.21 no.5
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    • pp.531-549
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    • 2021
  • Analytical models were developed and seismic behaviors were analyzed for a three-story stone pagoda at the Cheollyongsa temple site, which was damaged by the Gyeongju earthquake of 2016. Both finite and discrete element modeling were used and the analysis results were compared to the actual earthquake damage. Vulnerable parts of stone pagoda structure were identified and their seismic behaviors via sliding, rocking, and risk analyses were verified. In finite and discrete element analyses, the 3F main body stone was displaced uniaxially by 60 and 80 mm, respectively, similar to the actual displacement of 90 mm resulting from the earthquake. Considering various input conditions such as uniaxial excitation and soil-structure interaction, as well as seismic components and the distance from the epicenter, both models yielded reasonable and applicable results. The Gyeongju earthquake exhibited extreme short-period characteristics; thus, short-period structures such as stone pagodas were seriously damaged. In addition, we found that sliding occurred in the upper parts because the vertical load was low, but rocking predominated in the lower parts because most structural members were slender. The third-floor main body and roof stones were particularly vulnerable because some damage occurred when the sliding and rocking limits were exceeded. Risk analysis revealed that the probability of collapse was minimal at 0.1 g, but exceeded 80% at above 0.3 g. The collapse risks at an earthquake peak ground acceleration of 0.154 g at the immediate occupancy, life safety, and collapse prevention levels were 90%, 52%, and 6% respectively. When the actual damage was compared with the risk analysis, the stone pagoda retained earthquake-resistant performance at the life safety level.

Micromachining of Cr Thin Film and Glass Using an Ultrashort Pulsed Laser

  • Choi, Ji-Yeon;Kim, Jae-Gu;Shin, Bo-Sung;Whang, Kyung-Hyun
    • Journal of the Optical Society of Korea
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    • v.7 no.3
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    • pp.160-164
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    • 2003
  • Materials processing by ultrashort pulsed laser is actively being applied to micromachining technology due to its advantages with regard to non-thermal machining. In this study, materials processing with ultrashort pulses was studied by using the high repetition rate of a 800 nm Ti:sapphire regenerative amplifier. This revealed that the highly precise micromachining of metallic thin film and bulk glass with a minimal heat affected zone (HAZ) could be obtained by using near damage threshold energy. Grooves with diffraction limited sub-micrometer width were obtained with widths of 620 nm on Cr thin film and 800 nm on a soda-lime glass substrate. The machined patterns were investigated through SEM images. We also phenomenologically examined the influence of variations of parameters and proposed the optimal process conditions for microfabrication.

Development of A New Methodology for Evaluating Nuclear Safety Culture (원자력 안전문화의 정량화 방법론 개발)

  • Jae, Moosung;Han, Kiyoon
    • Journal of the Korean Society of Safety
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    • v.30 no.4
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    • pp.174-180
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    • 2015
  • This study developed a Safety Culture Impact Assessment Model (SCIAM) which consists of a safety culture assessment methodology and a safety culture impact quantification methodology. The SCIAM uses safety culture impact index (SCII) to monitor the status of safety culture of the NPPs periodically and it uses relative core damage frequency (RCDF) to present the impact of safety culture on the safety of the NPPs. As a result of applying SCIAM to the reference plant (Kori 3), the standard for the healthy safety culture of the reference plant is suggested. SCIAM might contribute to improve the safety of the NPPs (Nuclear Power Plants) by monitoring the status of safety culture periodically and presenting the standard of healthy safety culture.

DESIGN OF TRANSBUCCAL TROCAR TIP USED IN MANDIBULAR ANGLE FRACTURES (하악골 골절시 사용되는 TRANSBUCCAL TROCAR TIP의 새로운 고안)

  • Ahn, Byoung-Keun;Rhee, Gun-Ju;Han, Ho-Jin;Park, Hyoung-Tae
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.11 no.1
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    • pp.87-92
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    • 1989
  • Transbuccal trocar has been an established method of fixation for the bone plate in the case of mandibular angle fracture. Other than extraoral approaches, this transbuccal approach has many advantages in the treatment of the fracture of mandibular angle. These advantages are as follows ; (1) Damage to the facial nerve branches is minimal. (2) Less postoperative scar is formed. (3) Good vision of occlusion can be easily obtained on the entire operation. (4) Shorter operation time is needed. But, in the clinical procedure of plate fixation, it is has a difficulty in manipulation of the plate and correction of position. To solve these problems, we designed and used a trocar tip which can be easily attached to the trocar, and could make an improvement in the clinical procedures.

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Radiation Dosimetry for Radionuclide Therapy (동위원소 치료 관련 방사선 흡수선량평가)

  • Kim, Eun-Hee
    • 대한핵의학회:학술대회논문집
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    • 2001.05a
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    • pp.4-10
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    • 2001
  • The radionuclide therapy is a protocol for tumor control by administering radionuclides as the cytotoxic agents. Radionuclides concentrated at the site of cancerous lesion are expected to kill the cancerous cells with minimal injury to the normal tissue. The efficacy of every radionuclide treatment can be evaluated by examining the toxicity to the lesion differentiated from that to the normal tissue. Radiation dosimetry is the procedure of quantitating the energy absorbed by target volumes of interest. Dosimetric information plays an indicator of the expected radiation damage and thus the therapeutic efficacy. This paper summarizes the dosimetric aspects in radionuclide therapy in terms of radionuclides of use, radiation dosimetry methodology and considerations for each treatment in practical use.

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