• 한방비만학회지
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• 제6권1호
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• pp.11-26
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• 2006

Hair tissue mineral analysis is widely accepted for assessing essential and toxic elements which can give information about disease, metabolic disorder, nutritional imbalance, drug abuse, environmental exposure and so on. In Oriental Medicine, hair have been used as a diagnostic method which reflects the physiological and pathological status of body, especially kidney system(腎臟) and blood(血) like the quotations from Donguibogam(東醫寶鑑), 'hair belongs to kidney system(髮屬腎)' and 'hair is the remainder of blood(髮者血之餘)' Therefore we have suggested that HTMA have possibility to be utilized for screening and treatment for obesity, growth disorder, general deficiency syndrome(諸虛證), etc. in Oriental Medicine.

• 대한물리의학회지
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• 제15권1호
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• pp.95-104
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• 2020

PURPOSE: A prospective study was conducted to investigate the correlation between the inspiration ability, bone mineral density, lumbar muscle strength, and muscular endurance for the national softball athletes in the national training center. METHODS: The general characteristics of study subjects, inspiration ability, bone mineral density, muscle strength, and muscular endurance data were analyzed using descriptive statistics. In addition, the Pearson product moment correlation was performed to investigate the correlation between the inspiratory capacity, bone mineral density, muscle strength, and muscular endurance. RESULTS: The inspiration, flow rates, and volume were not correlated with the bone mass and bone mineral density. Inspiration and the flow rates and volume were not correlated with the bone mass and bone mineral density. On the other hand, inspiration was correlated with the Extensor muscles (r=.464, p=.006) at an angular velocity of 60°/s and the flexors (r=.463, p=.006) and extensor muscles (r=.615, p<.001) at an angular velocity of 180°/s. The flow rate was also correlated with the extensor muscles (r=.444, p=.009) at an angular velocity of 60°/s and with flexor muscles (r=.432, p=.011) and extensor muscles (r=.589, p<.001) at an angular velocity of 180°/s. Finally, the volume was correlated at the extensor muscles at an angular velocity of 180°/s (r=.534, p=.001). CONCLUSION: The correlation between the inspiratory capacity, bone mineral density, muscle strength, and muscular endurance of softball athletes did not correlate with the bone mass and bone density. On the other hand, the lumbar muscle strength increased with increasing inspiratory capacity.

• The Korean Journal of Physiology and Pharmacology
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• 제14권4호
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• pp.199-204
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• 2010

The potential therapeutic action of shikonin in an experimental model of rheumatoid arthritis (RA) was investigated. As a RA animal model, DBA/1J mice were immunized two times with type II collagen. After the second collagen immunization, mice were orally administered shikonin (2 mg/kg) once a day for 35 days, and the incidence, clinical score, bone mineral density (BMD), bone mineral content (BMC) and joint histopathology were evaluated. BMD in the proximal regions of the tibia largely increased in the shikonin treatment group compared with the control group. We also examined the effect of shikonin on inflammatory cytokines and cartilage protection. Shikonin treatment significantly reduced the incidence and severity of collagen-induced arthritis (CIA), markedly abrogating joint swelling and cartilage destruction. Shikonin also significantly inhibited the production of matrix metalloproteinase (MMP)-1 and up-regulated tissue inhibitors of metalloproteinase (TIMP)-1 in mice with CIA. In conclusion, shikonin exerted therapeutic effects through regulation of MMP/TIMP; these results suggest that shikonin is an outstanding candidate as a cartilage protective medicine for RA.

• Journal of Periodontal and Implant Science
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• 제44권5호
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• pp.227-234
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• 2014

Purpose: Dentin hypersensitivity is a potential threat to oral health. Laser irradiation may provide reliable and reproducible treatment but remains controversial. The present study aimed to evaluate the effects of $CO_2$ or erbium-doped yttrium aluminium garnet (Er:YAG) laser therapy, and to assess mineral content. Methods: Eighteen human single-rooted teeth affected with advanced periodontitis were obtained. Buccal and lingual surfaces were planed to form 36 specimens. Ethylenediaminetetraacetic acid gel (24%) was applied to remove the smear layer and simulate hypersensitive teeth. The experimental groups were: group 1, control (no irradiation); group 2, $CO_2$ laser (repetitive pulsed mode, 2 W, $2.7J/cm^2$); and group 3, Er:YAG laser (slight contact mode, 40 mJ/pulse and 10 Hz). To evaluate dentinal tubule occlusion, six specimens per group (2-mm thickness) were prepared and observed using scanning electron microscopy (SEM) for calculation of the occlusion percentage. To evaluate the mineral content, six specimens per group (0.6-mm thickness) were used, and then the levels of Ca, K, Mg, Na, and P were measured by inductively coupled plasma-atomic emission spectrometry. In addition, the surface temperature of the specimens during laser irradiation was analyzed by a thermograph. Results: The SEM photomicrographs indicated melted areas around exposed dentinal tubules and a significantly greater percentage of tubular occlusion in the $CO_2$ and Er:YAG laser groups than the control, and in the Er:YAG group than the $CO_2$ laser group. In addition, no significant differences were noted among the experimental groups for the mineral elements analyzed. The $CO_2$ laser group showed an evident thermal effect compared to the Er:YAG group. Conclusions: $CO_2$ and Er:YAG laser are effective in treating dentin hypersensitivity and reducing its symptoms. However, the Er:YAG laser has a more significant effect; thus, it may constitute a useful conditioning item. Furthermore, neither $CO_2$ nor Er:YAG lasers affected the compositional structure of the mineral content.

• 대한수의학회지
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• 제40권4호
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• pp.755-762
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• 2000

The aim of this investigation was to examine the effects of osteocalcin, bone-specific alkaline phophatase, estrogen, insulin-like growth factor-I (IGF-I), Ca, P and bone mineral density on osteoporosis induced by ovariectomy in rats. Female Sprague-Dawley 30 rats of three-forth's birth, weighing $215{\pm}10g$, were divided into two groups including the sham operation group(5 heads) and ovariectomy group(25 heads). They were fed normal diets for 2 weeks before the experimental operation and for 8 more weeks after operation. The level of osteocalcin, TALP, BALP, estrogen, bone mineral density and IGF-I were increased in experimental group, but a little increased in sham operation group at same period. The change of rates of osteocalcin, TALP, BALP, estrogen, bone mineral density and IGF-I were significantly higher in experimental group than sham operation group. $Ca^{2+}$ was not changed between two groups and P was significantly decreased in experimental group and Ca/P ratio was higher in experimental group than sham operation group. Body weights were increased in all two groups and growth rate per day was higher in experimental group than sham operation group. However, femur weight I body weight ratio was lower in experimental group than sham operation group.

• Journal of Korean Neurosurgical Society
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• 제54권5호
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• pp.384-389
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• 2013

Objective : Use of quantitative computed tomography (CT) to evaluate bone mineral density was suggested in the 1970s. Despite its reliability and accuracy, technical shortcomings restricted its usage, and dual-energy X-ray absorptiometry (DXA) became the gold standard evaluation method. Advances in CT technology have reduced its previous limitations, and CT evaluation of bone quality may now be applicable in clinical practice. The aim of this study was to determine if the Hounsfield unit (HU) values obtained from CT correlate with patient age and bone mineral density. Methods : A total of 128 female patients who underwent lumbar CT for back pain were enrolled in the study. Their mean age was 66.4 years. Among them, 70 patients also underwent DXA. The patients were stratified by decade of life, forming five age groups. Lumbar vertebrae L1-4 were analyzed. The HU value of each vertebra was determined by averaging three measurements of the vertebra's trabecular portion, as shown in consecutive axial CT images. The HU values were compared between age groups, and correlations of HU value with bone mineral density and T-scores were determined. Results : The HU values consistently decreased with increasing age with significant differences between age groups (p<0.001). There were significant positive correlations (p<0.001) of HU value with bone mineral density and T-score. Conclusion : The trabecular area HU value consistently decreases with age. Based on the strong positive correlation between HU value and bone mineral density, CT-based HU values might be useful in detecting bone mineral diseases, such as osteoporosis.

• Journal of Yeungnam Medical Science
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• 제14권2호
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• pp.383-392
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• 1997

미숙아를 포함한 신생아에서의 재태 연령에 따른 골밀도의 차이를 관찰하여 향후 대사성 골질환의 진단을 기초 자료로 삼기 위하여, 1995년 3월 1일부터 1997년 2월 28일까지 영남대학교 의과대학 부속병원에서 출생한 신생아 중 자궁내 성장 발육 이상 소견이 없고, 생후 1주일이내에 골밀도 측정이 가능하였던 53명을 대상으로 이중에너지 X-선 흡수계측법 (dual energy X-ray absorptiometry, DXA, X-R 26, Norland, U.S.A.)을 사용하여 생후 1주일내의 요추에서의 골밀도를 측정하여 다음과 같은 결과를 얻었다. 1. 골밀도는 성별에 따른 차이는 없었고, 재태 연령군별 골밀도는 재태 연령 28-30주군의 $0.149{\pm}0.009g/cm^2$에서부터 39-41주군의 $0.229{\pm}0.034g/cm^2$까지 재태 연령의 증가에 따라 함께 증가를 보여 33-34주군과 35 - 36주군 사이를 제외한 재태 연령군별 골밀도는 유의한 차이를 보였으며 (p<0.05), 재태 연령이 28주 3일에서 41주 3일로 증가함에 따라 골밀도는 직선적인 상관관계를 나타내었다 ($Y=7.5{\times}10^{-3}X-0.082$, r=0.7018, p<0.001). 2. 출생체중별 골밀도는 1,000-1,499그람군의 골밀도는 $0.158{\pm}0.020g/cm^2$을 나타내었고, 3,500-4,000그람군의 골밀도는 $0.251{\pm}0.021g/cm^2$를 나타내어 출생 체중군별 골밀도는 1,000-1,499그람군과 1,500-1,999그람군 사이를 제외한 모든 체중군별로 유의한 차이를 나타내었다 (p<0.05). 출생체중이 1,250그람으로부터 3,880그람까지 증가하는데 따라 골밀도는 유의하게 증가하며 직선적인 상관관계를 나타내었다 ($Y=3.9{\times}10^{-5}X+0.093$, r=0.7296, p<0.001). 재태연령이 증가할수록, 출생체중이 증가할수록 골밀도가 증가하는 것을 관찰하였으며, 이는 향후 미숙아를 포함하는 신생아에 대한 골밀도 변화를 관찰하는 기초 자료가 될 수 있다고 생각된다.

• 대한디지털의료영상학회논문지
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• 제10권2호
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• pp.5-10
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• 2008

Thanks to recent development of science and technology, economic standard has been improved and life expectation has been gradually increased. Accordingly, disease aspect and demand for health have been changed in the concept from conventional center of disease to health improvement As the health issue in middle and senior age has also been vital in the national health, osteoporosis, one of the physical maladies occuring in these age group, is on the rise as a matter of important concern so that the researches on the osteoporosis have being accomplished actively in several medical domains. Research has been earned out for 735 examined objects, who have received medical examination of bone mineral density in the volunteer medical service of Daegu and Kyungbuk province for recent 4 years. The result indicated that serious osteoporosis prevailed over osteoporosis for male while osteopenia was majority to osteoporosis and that abnormal bone mineral density was more prominent than normal bone mineral density for both male and female. This study is to present basic data which is indispensible to preparation of senior citizen dominated society afterward, investigating the prevalence rate of osteoporosis.

• 동의생리병리학회지
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• 제18권6호
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• pp.1548-1551
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• 2004

studied on the physicochemistrical property of the clean active water depositting on the ceramic stone by the mineral-Oriental medicine. The results are as follows. The cluster of the clean active water is observed 53-66.5㎐ for contral water. The clean active water is observed 7.2 ph and 1.3330 refractive index for contral water. In the chemical experimental test by ICP, the clean active water is observed 102℃ in boiling point and 4.8㎎/100g V.E for 0㎎g/100g of contral water. In the antibiotic experimentation, an anion, the dimintion index of bacilli, radiation degree and radiate energy of the clean active water increased for contral water. And in the deodorization experimentation, the clean active water is observed 95% deodorization index.

• 핵의학기술
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• 제28권1호
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• pp.13-17
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• 2024

Bone Mineral Densitometry (BMD) values is determined numerically with T or Z-score while the image is not considered in the interpretation. Abnormal finding was observed in the left femoral bone density image of a 64-year-old female patient who underwent a left kidney transplantation. This was due to the ethiodized oil used for embolization in the treatment of lymphatic leakage. Radiologic technologists should not only monitor changes of BMD values, but keep in mind to assess the changes in the image to provide accurate information to the patient.