• Title/Summary/Keyword: mild schedule

검색결과 21건 처리시간 0.023초

미송(美松)의 열기건조(熱氣乾燥)스케쥴 개선(改善)에 관(關)한 연구(硏究) (Study on Kiln-Schedule Modification for Douglas Fir)

  • 정희석;챨리 코즈리크;헬므쓰 레슈
    • Journal of the Korean Wood Science and Technology
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    • 제12권1호
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    • pp.31-37
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    • 1984
  • For the modification of kiln drying schedule, relations between resistance to drying Rd and the moisture content or drying times were found for 4/4, 6/4 and 8/4 green Douglas fir heartwood by the mild drying schedule and the severe drying schedule until the average moisture content was about 10 percent. The results of this study were as follows. 1. Resistance to drying of thicker lumber was higher than that of thinner lumber and resistance to drying of three different thicknesses were negligible between the mild-and the severe drying schedule. The relationships between resistance to drying and two schedules or three thicknesses of lumber were $Rd_1=1.830{\times}10^5\;M^{-2.24}$ for 4/4 lumber by the mild drying schedule, $Rd_2=1.822{\times}10^5\;M^{-2.25}$ for 4/4 lumber by the severe drying schedule, $Rd_3=2.352{\times}10^5\;M^{-2.14}$ for 6/4 lumber by the mild drying schedule, $Rd_4=3.457{\times}10^5\;M^{-2.27}$ for 6/4 lumber by the severe drying schedule, $Rd_5=1.317{\times}10^6\;M^{-2.56}$ for 8/4 lumber by the mild drying schedule, $Rd_6=8.267{\times}10^5\;M^{-2.40}$ for 8/4 lumber by the severe drying schedule. 2. Thinner lumber exhibited lower level of moisture content and shorter drying time required at intersection point between the moisture content and resistance to drying as a function of drying time than those of thicker lumber. Drying time of mild drying was longer than that of severe drying and similar to the level of moisture content at intersection point.

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침엽수 제재두께별 가열판 압체식 진공건조의 소요 에너지 (Energy Consumption in Vacuum-Press Drying of Some Softwood Lumbers of Different Thicknesses)

  • 정희석;이준호;강욱;이남호
    • Journal of the Korean Wood Science and Technology
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    • 제29권1호
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    • pp.9-15
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    • 2001
  • 침엽수 4수종(소나무, 잣나무, 낙엽송, 웨스턴 햄록)의 가열판 압체식 진공건조에서 소요되는 비에너지 곡선은 함수율 감소에 따라 서서히 증가, 거의 일정, 급속 증가 등 3단계의 증가 패턴을 나타내었고, 제재두께별 계산된 비에너지는 3cm 제재 0.483, 5cm 제재 0.649, 7cm 제재 0.814, 9cm 제재 0.977 및 11cm 제재 1.138kWh/kg로서 두께가 증가함에 따라 거의 직선적으로 증가하였고, 강한 건조스케줄을 적용한 비에너지는 약한 건조스케줄의 것보다 적었으며, 가열판 진공건조의 평균 비에너지는 0.712kWh/kg으로서 다른 건조법의 것보다 적었다.

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감맥대조탕 복합추출물의 만성스트레스 유발 생쥐의 항우울 작용에 관한 실험연구 (Experimental Study on the Anti-Depressant Effects of Gammakdaejo-tang Complex Extracts in Rats Induced with Chronic Mild Stress)

  • 이유찬;김보경
    • 동의신경정신과학회지
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    • 제29권1호
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    • pp.57-68
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    • 2018
  • Objectives: To experimentally assess the anti-depressant effects of Gammakdaejo-tang Complex Extracts (GMDJ-Tang) in rats. Methods: Twenty Wistar Hannover (160~170 g) stressed rats were treated with different concentrations of GMDJ-Tang extracts i.e., 0, 62.5 mg/kg, 125 mg/kg, and 250 mg/kg. Chronic mild stress was induced by food deprivation, empty bottles, forced swimming, flickered light, tilt cages, shaking cages, high density breeding, water deprivation, and by soaking the litter cover according to fixed schedule. Blood and brain tissue samples were collected for biochemical analysis. Tests included serotonin and ELISA assays. Results: GMDJ-tang increased the weight of treated rats as well as levels of serotonin, BDNF and TrkB; however, the differences were not significant. In contrast, the extracts significantly decreased blood glucose in stressed rats. GMDJ-tang extracts did not significantly impact Serum AST, ALT, leukocytes, erythrocytes and thrombocytes when comparing treatment groups to control rats. Likewise, hemoglobin, hematocrit and PLT increased in treatment groups following treatment with GMDJ-tang, but this change was without significance. Conclusions: These results suggest that GMDJ-tang can alleviate chronic mild stress in rats, possibly through anti-depressant activity.

우울증(憂鬱症)모델 흰쥐에 대한 조위승청탕(調胃升淸湯)과 fluoxetine의 항우울효과(抗憂鬱效果) 비교 (The effects of Jowiseungchungtang versus fluoxetine in the chronic mild stress model of depression in rats)

  • 류재면;김종우;지상은;김은주;박은혜;황의완
    • 동의신경정신과학회지
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    • 제15권1호
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    • pp.27-41
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    • 2004
  • This study was performed to evaluate the effects of Jowiseungchungtang and fluoxetine in the chronic mild stress(CMS) model of depression in rats. Chronic exposure to mild unpredictable stress was found to depress the consumption of sucrose solution in rats for 5 weeks. These CMS-treated rats were stratified into Jowiseungchungtang group, fluoxetine group and vehicle group. And control rats were also stratified into other CMS-treated group. The change of the consumption of sucrose solution was measured, and open field test were performed to investigate the anti-depression effect of Jowiseungchungtang and fluoxetine. The results were as follows : 1. The consumption of sucrose solution was significantly reversed in Jowiseungchungtang-treated group at 7 week, but there was no significant change in other groups. 2. CMS schedule decreased body weight. Jowiseungchungtang group and fluoxetine group showed significant decrease of body weight after 6 weeks. 3. In open field test, Jowiseungchungtang group and fluoxetine group showed no significant change of exploratory activity.

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강원도산(江原道産) 참나무과(科) 4수종(樹種)의 추정건조(推定乾操)스케줄(제2보) (The Estimated Drying Schedule of Fagaceae Four Species Grown in Kangwon-Do (II))

  • 박종수;김수창
    • Journal of Forest and Environmental Science
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    • 제12권1호
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    • pp.1-12
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    • 1996
  • 강원도산(江原道産) 참나무과(科) 4수종(樹種)의 건조특성(乾操特性)을 파악코져 $100^{\circ}C$에서 급속건조(急速乾操)를 실시하여 건조중(乾操中) 함수율(含水率)과 건조경과(乾操經過), 초기할열(初期割裂)(목구할열(木口割裂)과 표면할열(表面割裂)), 찌그러짐, 내부할열(內部割裂) 등의 건조결함(乾操缺陷)을 조사하여 추정건조(推定乾操)스케쥴을 작성한 결과(結果)는 다음과 같다. 건조시간별(乾操時間別) 건조중(乾操中) 함수율(含水率)은 초기함수율(初期含水率)이 높은 판재일수록 급속(急速)한 곡선적(曲線的) 감소(減少)를 나타내었고 건조소요시간(乾操所要時間)은 두께가 두꺼울수록, 초기함수율(初期含水率)이 높을수록, 건조중(乾操中) 함수율(含水率) 변화( 變化)가 느린 수종(樹種)일수록 길었다. 또한, 두께가 두꺼울수록 할열(割裂)의 발생량(發生量)이 증가하므로 건조초기(乾操初期)의 조건(條件)을 완화하게 해야 함을 알 수 있었다.

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A novel schedule of accelerated partial breast radiation using intensity-modulated radiation therapy in elderly patients: survival and toxicity analysis of a prospective clinical trial

  • Sayan, Mutlay;Wilson, Karen;Nelson, Carl;Gagne, Havaleh;Rubin, Deborah;Heimann, Ruth
    • Radiation Oncology Journal
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    • 제35권1호
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    • pp.32-38
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    • 2017
  • Purpose: Several accelerated partial breast radiation (APBR) techniques have been investigated in patients with early-stage breast cancer (BC); however, the optimal treatment delivery techniques remain unclear. We evaluated the feasibility and toxicity of APBR delivered using intensity-modulated radiation therapy (IMRT) in elderly patients with stage I BC, using a novel fractionation schedule. Materials and Methods: Forty-two patients aged ${\geq}65$ years, with stage I BC who underwent breast conserving surgery were enrolled in a phase I/II study evaluating APBR using IMRT. Forty eligible patients received 40 Gy in 4 Gy daily fractions. Patients were assessed for treatment related toxicities, and cosmesis, before APBR, during, and after completion of the treatment. Results: The median age was 73 years, median tumor size 0.8 cm and the median follow-up was 54 months. The 5-year locoregional control was 97.5% and overall survival 90%. Erythema and skin pigmentation was the most common acute adverse event, reported by 27 patients (69%). Twenty-six patients (65%) reported mild pain, rated 1-4/10. This improved at last follow-up to only 2 (15%). Overall the patient and physician reported worst late toxicities were lower than the baseline and at last follow-up, patients and physicians rated cosmesis as excellent/good in 93% and 86 %, respectively. Conclusion: In this prospective trial, we observed an excellent rate of tumor control with daily APBR. The acceptable toxicity profile and cosmetic results of this study support the use of IMRT planned APBR with daily schedule in elderly patients with early stage BC.

우울증유발(憂鬱症誘發) 흰쥐에 대한 귀비양(歸脾揚)의 항우울효과(抗憂鬱效果) (The Effects of Quibitang in the Chronic Mild Stress Model of Depression in Rats)

  • 성우용;황의완;박은혜;이정륜;김현택;김종우
    • 동의신경정신과학회지
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    • 제13권2호
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    • pp.121-147
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    • 2002
  • This study was performed to evaluate the effects of Quibitang in the chronic mild stress(CMS) model of depression in rats. Chronic exposure to mild unpredictable stress was found to depress the consumption of sucrose solution in rats for 8 weeks. These CMS-treated rats were stratified into Quibitang gruop and saline group. And control rats were also stratified into Quibitang group and saline group. The change of the consumption of sucrose solution and the body weight were measured, and open field test, elevated startle response and plus maze test were performed, to investigate the anti-depression effect of Quibitang. The results were as follows: 1. The consumption of sucrose solution was significantly reversed in Quibitang-treated group at 9th, 11th, 12th week, but there was no significant change at 10th week 2. CMS schedule decreased body weight. CMS-treated groups showed decrease of body weight after 5 weeks. After 10 weeks, Quibitang group showed lower body weight than saline group in CMS-treated groups 3. In open field test, Quibitang group showed significant difference of locomotion, latency. 4. In elevated startIe test, Quibitang group showed no significant change of startle response. 5. In plus maze test, Quibitang group showed no significant change of plus maze-time and plus maze-error.

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공황장애 환자의 1년 자연 경과 추적 연구 (One Year Naturalistic Outcome Study of Panic Disorder Patients)

  • 김민후;이동은;정석훈;송해철;한오수;이선형;권수희;홍진표
    • 대한불안의학회지
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    • 제2권2호
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    • pp.108-114
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    • 2006
  • Objectives : Only a few prospective studies of panic disorder are available. This study investigated naturalistic outcome of panic disorder patients at twelve months after the initial diagnosis. Methods : A total of 84 subjects were diagnosed with panic disorder by diagnostic interview, Structured Clinical Interview for DSM-IV (SCID-IV) and Anxiety Disorder Interview Schedule for DSM-IV (ADISIV). Among them, 80 subjects could be evaluated by means of Panic Disorder Severity Scale (PDSS) at follow-up interview after twelve months. Treatment continuation was also examined at follow-up interview. Results : At initial intake, 80 patients were classified into 22% with mild, 33% with moderate-to-marked, and 45% with severe symptoms on the basis of their PDSS total score. At twelve months, 20% of patients reached remission, 65% had mild and 15% had moderate-to-marked symptoms. Initial panic symptom severity, presence of agoraphobia, panic symptom duration before diagnosis, number of comorbid Axis I disorders were associated with significantly higher PDSS total score at twelve months. Forty six percent of total patients continued medication and 23% have stopped treatment by clinician's recommendation and 31% have selfdiscontinued their medication. At twelve months, all three groups were improved but self-discontinuation group had significantly higher PDSS total score. Conclusion : In the one-year naturalistic outcome study of panic disorder patients, high percentage of patients achieved remission or had mild symptoms.

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Adverse Events Following Immunizations in Infants Under 1 Year of Age in Lorestan Province, Western Iran

  • Anbari Khatereh;Ghanadi Koruosh;Toulabipour Alireza;Jamebozuorghi Daryuosh;Baharvand Parastoo
    • Journal of Preventive Medicine and Public Health
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    • 제56권2호
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    • pp.172-179
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    • 2023
  • Objectives: Vaccination is an important intervention for preventing disease and reducing disease severity. Universal vaccination programs have significantly reduced the incidence of many dangerous diseases among children worldwide. This study investigated the side effects after immunization in infants under 1 year of age in Lorestan Province, western Iran. Methods: This descriptive analytical study included data from all children <1 year old in Lorestan Province, Iran who were vaccinated according to the national schedule in 2020 and had an adverse event following immunization (AEFI). Data were extracted from 1084 forms on age, sex, birth weight, type of birth, AEFI type, vaccine type, and time of vaccination. Descriptive statistics (frequency, percentage) were calculated, and the chi-square test and Fisher exact test were used to assess differences in AEFIs according to the abovelisted variables. Results: The most frequent AEFIs were high fever (n=386, 35.6%), mild local reaction (n=341, 31.5%), and swelling and pain (n=121, 11.2%). The least common AEFIs were encephalitis (n=1, 0.1%), convulsion (n=2, 0.2%), and nodules (n=3, 0.3%). Girls and boys only showed significant differences in mild local reactions (p=0.044) and skin allergies (p=0.002). The incidence of lymphadenitis (p<0.001), severe local reaction (p<0.001), mild local reaction (p=0.007), fainting (p=0.032), swelling and pain (p=0.006), high fever (p=0.005), and nodules (p<0.001) showed significant differences based on age at vaccination. Conclusions: Immunization is a fundamental public health policy for controlling vaccine-preventable infectious diseases. Although vaccines such as the Bacillus Calmette-Guérin vaccine, oral poliovirus vaccine, and pentavalent vaccine are well-researched and reliable, AEFIs are inevitable.

Bayesian Method on Sequential Preventive Maintenance Problem

  • Kim Hee-Soo;Kwon Young-Sub;Park Dong-Ho
    • Communications for Statistical Applications and Methods
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    • 제13권1호
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    • pp.191-204
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    • 2006
  • This paper develops a Bayesian method to derive the optimal sequential preventive maintenance(PM) policy by determining the PM schedules which minimize the mean cost rate. Such PM schedules are derived based on a general sequential imperfect PM model proposed by Lin, Zuo and Yam(2000) and may have unequal length of PM intervals. To apply the Bayesian approach in this problem, we assume that the failure times follow a Weibull distribution and consider some appropriate prior distributions for the scale and shape parameters of the Weibull model. The solution is proved to be finite and unique under some mild conditions. Numerical examples for the proposed optimal sequential PM policy are presented for illustrative purposes.