• Journal of Nutrition and Health
• /
• 제38권1호
• /
• pp.56-66
• /
• 2005

The purpose of this study was to assess the zinc and copper status of type 2 diabetic women and to analyse the relation-ship among zinc and copper status, and diabetic control indices of diabetes. The mean age of diabetes was 57.9 years old. The mean duration of diabetes was 8.0 $\pm$ 6.5 years. The mean daily energy intake of diabetes was 1562 kcal. There were no significant differences of age, BMI, %body fat, nutritional intakes, total energy intake, and energy composition from carbohydrate, protein, and fat between diabetes (n = 50) and control group (n = 68). However, both zinc intake density (4.15 mg/1000 kcal) and zinc %RDA (62.0%) of diabetes were significantly lower than control group (p <0.05, P < 0.01, respectively). The plasma zinc level was not significantly different between diabetes and control group (90$\mu$g/dl, 91$\mu$g/dl respectively). The proportion of diabetic women whose plasma zinc levels were lower than 76 $\mu$g/dl(borderline zinc deficiency) was 18.8%. This was about 38% higher than control group. It has been suggested that insulin secretion might decrease in borderline plasma zinc and copper deficiency and increase in normal plasma zinc and copper status. The urinary zinc excretion was twice higher in diabetes than in control group (p < 0.001). The urinary zinc loss was positively correlated with the duration of diabetes (p < 0.05), hyperglycemia (p < 0.001) and insulin resistance (p < 0.05). These results lead us to conclude that normal blood glucose level controlled by diet therapy could improve the hyperzincuria in diabetic women.

• Journal of Nutrition and Health
• /
• 제14권4호
• /
• pp.209-219
• /
• 1981

To evaluate long-term metabolic response of free-living Korean subjects consuming local sources adequately or slightly below habitual intake. Subjects, six male medical students aged 23-25 years were free-living, but consumed diets in the metabolic unit. They were healthy as determined from medical laborarory tests. They belong to the Korean middle-class. Temperature of outdoor during study were ranged between -2 to $26^{\circ}C$, whereas the indoor were $18-22^{\circ}C$. Animal protein ranged between 25-30% of total calorie. The three meals and a vitamin supplement to meet recommendation were given daily. Three 50day periods following the design were used to test the protein-energy adequacy of the diet. Urinary nitrogen excretion was measured daily. Fecal samples were pooled for the last 5 days of each week. Nitrogen balance was computed using 5mg N/Kg skin and miscellaneous losses. Body weight was measured daily. The study was covered on 126 metabolic observations weekly. Body weight changes were relatively stable with the energy intake of 37-44Kca1/kg, and N-balances were also relatively stable, but it was influenced by physical and or mental stress somehow. It could be assumed that the mean protein and energy requirement were $190{\pm}10mg$ N/Kg with $41{\pm}2$ Kcal/kg, and the mean digestibility of protein was 81% on these subjects with the experimental conditions. The protein requirement, however, could be cut down somewhat with some limited increaing of energy intake under parameters of N-balance and maintaining body weight. It was also observed a tendency of the requirement were getting smaller with the increase of body size.

• Journal of Nutrition and Health
• /
• 제39권8호
• /
• pp.773-785
• /
• 2006

Vitamin E in the body system plays an important role in preventing chronic diseases by decreasing the oxidative stress by free-radicals. However, there are not enough researches on analyzing the primary factors affecting vitamin E levels in the blood in Korean adults. Therefore, the purpose of this research was to examine blood tocopherol levels and the primary factors affecting the status. A complete lifestyle survey was performed on 314 Korean adult men and surveyed their smoking, drinking and exercising habits. The average plasma level of ${\alpha}-\;and\;{\gamma}-tocopherol$ showed similar mutual relations with plasma total cholesterol (TC), triglyceride (TG), or low density lipoprotein cholesterol (LDL-C) levels (p<0.001). Plasma ${\alpha}-tocopherol$ level of the subjects did not show any difference as smoking, drinking and exercising habits changed. However, ${\gamma}-tocopherol$ per TG showed much lower figure in smokers than non smokers (p < 0.05). Amongst diet factors, plasma ${\alpha}-tocopherol$ level showed negative correlations with Vitamin E intake, while ${\gamma}-tocopherol$ level showed positive correlations with Vitamin E intake. Erythrocyte superoxide dismutase (SOD) activity and plasma tocopherol showed negative correlations, and catalase activity and plasma ${\alpha}-tocopherol$ showed positive correlationship. The level of cell DNA damage of Iymphocyte and plasma ${\alpha}-\;or\;{\gamma}-tocopherol$ showed negative correlations. As a result of this research, the factors that affect Korean adult men's plasma ${\alpha}-tocopherol$ level are plasma TG, LDL-C and cell DNA damage in Iymphocyte, while the factors that affect ${\gamma}-tocopherol$ level are plasma TG, LDL-C and vitamin E intake based on multiple regression analysis. These findings implies that the level of different types of tocopherol depends on slightly different factors. A further research is needed on the factors involved in the differentiation of the types of tocopherol.

• 대한화장품학회:학술대회논문집
• /
• 대한화장품학회 2003년도 IFSCC Conference Proceeding Book I
• /
• pp.387-412
• /
• 2003

Influence of gelatinase on basement membrane (BM) structure was investigated by using a skin equivalent (SE) model. The results showed that (1) gelatinase produced by cells degraded the BM and (2) the addition of matrix metalloproteinase-specific inhibitor to the SE medium accelerated the formation of BM structure, indicating that gelatinase is involved in BM impairment. The activity of gelatinase was also studied in healthy human facial skin tissues. The result of in situ zymography revealed gelatinase activity around the basal layer of the epidermis, where BM integrity was severely compromised. Therefore, this enzyme was suggested to be associated with BM decomposition in human facial skin. To assess the behavior of gelatinase in stratum corneum (SC) non-invasively, an immunological study was performed. Since positive immunostaining of pro-gelatinase B was observed in SC stripped from sun-exposed skin, whereas no positive staining detected in SC of non-irradiated skin, gelatinase in the epidermis could be non-invasively detected by measuring gelatinase in SC. Gelatinase in SC of healthy female volunteers was monitored using a special film that sensitively and conveniently detects gelatinase. Ninetr percent of SC from facial skin (l00 women, 40's-50's) was gelatinase-positive. On the other hand, SC from non-irradiated skin was negative. These results strongly suggest that (1) gelatinase is constantly produced in the facial epidermis of most middle-aged woman during their daily life, and (2) the enzyme might be involved in the aging-related degeneration of both BM and the matrix fibers of the upper layer of the dermis, acting as a very important aging factor. Strong inhibitory activity against gelatinase was found in turmeric extract and identified curcumin as the major ingredient. Topical application of cream containing turmeric extract significantly decreased the number of gelatinase-positive SC clusters in human facial skins. These results indicated that turmeric is an effective ingredient to prevent skin from photo aging by suppressing chlonically upregulated gelatinase activity by UV and to improve skin condition.

• 수산해양교육연구
• /
• 제27권1호
• /
• pp.160-169
• /
• 2015

The purpose of this study was to search and analyze the realities and needs of life long education, the necessity and perception of life competencies and the difference of competencies on experiences of education to support life long education system for adult learners in Busan and Ulsan. In this study, we conducted a questionnaire survey of 234 adult learners living in Busan and Ulsan. The results of this study were summarized as follows. First, adult learners perceived that life long education was very important to adults and appreciated an educational institution being managed by government. Second, adult learners thought that basic literacy competency and basic work competency were important and late fifties perceived that professional job is in important. Third, adult learners perceived that self directed learning and capacity of management are poor competencies. And they perceived that the government support adult learners who has economical difficulty. Forth, adult learners perceived that it was normal that 'professional job' and 'job transition abilities', 'women', 'the middle aged and old','the unemployed' and' low incomers' perceived that they have poor level. Fifth, according to the results of ${\chi}^2$ test for determining the statistical significance of differences in experience in lifelong learning among adult learner groups divided by their individual background, significant differences were observed in a few competencies(p<.05, p<.01).

• 대한기관식도과학회지
• /
• 제2권2호
• /
• pp.232-237
• /
• 1996

Burning and lump sensation in the throat is a common disorder in middle aged woman. It is generally considered to be a neurotic origin but its pathophysiology is still remained unknown. The purpose of this study was to evaluate the prevalence of the Pharyngoesophageal structural lesions and the esophageal motility disorders among the patients with globus pharyngeus and to elucidate whether any specific manometric abnormality might have any causative role in the pathogenesis of the globus sensation, and we also wanted to know whether such tests were necessary in evaluating those patients. Structural lesions were demonstrated in 21 cases(17.5 %) among 120 patients. But among 44 controls, there were also Two cases(4.5 %) of structural lesions, and there was less significantly difference in the prevalence of the structural lesions between the patients and controls(p=0.0625) Manometric abnormalities over the lower esophageal sphincter and the lower esophageal body were demonstrated in 28 cases (23.3 %) of the patients, while only one case (2.3 %) of the controls revealed such abnormality ( p=0.0037). Various manometric parameters of the upper esophageal sphincter and pharynx showed no difference between the patients and controls except the upper esophageal sphincter pressure at lateral sides which was lower in patients than in controls (p=0.0034). Globus sensation is a kind of symptom of esophageal dysmotility, and esophageal manometry is necessary to detect such abnormality in patients with globus sensation, Careful physical examination is also necessary to detect structural lesions in the pharynx and esophagus.

• Journal of Oral Medicine and Pain
• /
• 제22권2호
• /
• pp.383-394
• /
• 1997

The purpose of this study was to examine the anatomic changes in the upper airway with a dental orthosis. the effectiveness and side effects of orthosis in the treatment of snoring and obstructive sleep apnea. To meet this puppose a dental orthosis, designed to increase the size of the upper airway by advancing the mandible, was used in 42 patients (30 M, 12 F), aged 29 - 69 years, to treat snoring and varying decrees of obstructive sleep apnea. Cephalometric study of anatomic featured was made with and without a dental orthosis, and the evaluation of the effectiveness and side effects of orthosis was done by questionnaires. The obtained results were as follows : 1. All subjects were habitual snorers and 32 patients comp1ained the loudness of snoring as severe as be heard outside of the patient's room. 2. According to the degree of respiratory distirbance index(RDI) and aprea index(Al) from the polysomnograph in 34 patient, mild obstructive sleep apnea patients were 5, moderate 6 and severe 16. 3. Various anatomic changes in the upper airway with denta1 orthosis were as follows : (1) More superioly positioned hyoid bone ( p<0.001) (2) Enlarged oropharyngeal (superior p<0.01, middle p<0.01. inferior p<0.01) and hypopharyngeal (P<0.05) airway space. 4. According to the results of the changes of clinical syptoms after the usage of the dental orthosis acquired from questionnaires, there was significant improvement in the frequently, the loudness and the severity of snoring, cessation of breathing and awakening from the difficulty of breathing during sleep. 5. The effectiveness and side effects of dental orthosis by questionnaires were as follows ; (1) Dental orthosis satisfied almost all the patients (68±20%). (2) Snoring was improved in all the patients (73±19%). (3) Obstructive sleep aphea was improved in all the patients (61 ± 37%) (4) Sleepiness in the daytime was significantly improved (61 ±37%). (5) The sleep quality was significantly improved (61±37%). (6) The discomfort of the dental orthosis was minor (33±18%) and no serious complications were observed. 6. The dental orthosis is an effective treatment for the symptom of snoring, and it can also effectively treat varying degrees of obstructive sleep apnea.

• Asian Pacific Journal of Cancer Prevention
• /
• 제16권7호
• /
• pp.2731-2737
• /
• 2015

Background: The majority of deaths from cancer occur in low and middle income countries, partly due to poor public awareness of the signs and symptoms of cancer. Materials and Methods: A community based survey using the Cancer Awareness Measure (CAM) questionnaire was conducted in three different communities in Oman. Omani adults aged 18 years and above were invited to participate in the study. Results: A total of 345 responded from 450 invited participants (response rate=76.7%). The majority of respondents were unable to identify the common signs and symptoms of cancer identified in the CAM (average awareness was 40.6%). The most emotional barrier to seeking help was worry about what the doctor might find (223, 64.6%); a practical barrier was too busy to make an appointment (259, 75.1%) and a service barrier was difficulty talking to the doctor (159, 46.1%). The majority of respondents (more than 60% for seven out of ten symptoms) would seek medical help in two weeks for most signs or symptoms of cancer. Females were significantly more likely than males to be embarrassed (p<0.001), scared (p=0.001), and lack confidence talking about their symptoms (p=0.022). Conclusions: Urgent strategies are needed to improve public awareness of the signs and symptoms of cancer in Oman. This might leads to earlier diagnosis, improved prognosis and reduced mortality from cancer.

• 가정과삶의질연구
• /
• 제21권5호
• /
• pp.13-24
• /
• 2003

Regarding leisure and work as very important in residential life of old ages, this study analyzed their preference by leisure and work for senior congregate housing, which can provide proper work and leisure activities for older people who are able to manage their social activities with healthy condition. It conducted a survey of middle aged of the 50's who would face problems of senior housing in 2010, with stratified sampling by region, sex and housing structure type. Totally 556 Questionnaires were used for the final analysis. The research results showed that, first, the group which was positive toward their works mostly had spouse of the age of early 50' s and work for professional, technological, managerial positions with good health. Second, the more positive group towards their work showed high willingness to move in senior congregate housing, than a negative group towards their work, and put a weight on the openness of shared space and facilities as well as various alarming equipments, common space, common programs and the ability of managers. Third, according to the attitudes toward leisure activities, there were differences in each group by housing structure type, education of their own or their spouses, monthly income, property, economic ability, health condition, living together with spouse, housing tenureship, and usable area of houses. The fourth was that those who enjoy active leisure activities presented high willingness to move in senior congregate housing than those of negative attitude and also there was a difference in managerial ways. Throughout the results of the study, it appeared that a group of positive attitude toward work and leisure, than that of negative attitude, recognized the importance of senior congregate housing which social and leisure programs could support. It implied necessary to develop housing for the older people who have enough ability to manage their leisure activity as well as their work. The study is likely to have a contribution to suggest practical data for helping the development of housing for self-reliant seniors by analyzing their preference on senior congregate housing by their attitudes toward work. The research for the factors of various designs and managements by leisure and work may become the following research theme of the study.

• 가정과삶의질연구
• /
• 제28권2호
• /
• pp.27-37
• /
• 2010

The purpose of the study was to analyze the constraints that are normally experienced before moving in the context of the household characteristics of households that had recently moved to newly-built apartments. The data for the analysis was collected through a self-administered questionnaire from July 1, 2008 to August 10, 2008. The sample consisted of 251 households in Ulsan living in an apartment complex who had moved within a year. The data from the sample was analyzed by descriptive statistics, factor analysis, and analysis of variance with Duncan's multiple range tests. The results are as follows. The constraints were categorized into information gathering, attractive housing characteristics, expectations of residential mobility, housing development and policies, and resources. Overall, the constraints did not have a huge impact on the performance of the residential mobility of the sample households. Resources, however, were the most influential factors among the five constraints followed by attractive housing characteristics, information gathering, etc. The constraints varied based on the demographic characteristics, such as the household size, duration of marriage, age of the household head, and the socio-economic characteristics, such as the education level of the household head, household income, and the number of mobility. As the number of family members increased, the age of the household head went up, or the level of education went down, the constraints on information gathering were affected in terms of performing residential mobility. Households with a middle aged head with a professional occupation were more constrained by the attractive characteristics of the housing. The impact of the resources related constraints was significantly different based on the number of family members, marriage duration, and the household head's age and occupation, and the number of mobility.