• Title/Summary/Keyword: microscopic examination

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On the material properties of shell plate formed by line heating

  • Lim, Hyung Kyun;Lee, Joo-Sung
    • International Journal of Naval Architecture and Ocean Engineering
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    • v.9 no.1
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    • pp.66-76
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    • 2017
  • This paper is concerned with investigating the plastic material properties of steel plate formed by line heating method, and is aimed at implementing more rational design considering the accidental limit states such as collision or grounding. For the present study, line heating test for marine grade steel plate has been carried out with varying plate thickness and heating speed, and then microscopic examination and tensile test have been carried out. From the microscopic, it is found that the grain refined zones like ferrite and pearlite are formed all around the heat affected zone. From the tensile test results, it is seen that yield strength, tensile strength, fracture strain, hardening exponent and strength coefficient vary with plate thickness and heat input quantity. The formulae relating the material properties and heat input parameter should be, therefore, derived for the design purpose considering the accidental impact loading. This paper ends with describing the extension of the present study.

MR Imaging and Histological Findings of Experimental Cerebral Fat Embolism in Cats

  • Park Byung-Rae;Ko Seong-Jin;Kim Hwa-Gon
    • Biomedical Science Letters
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    • v.10 no.3
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    • pp.285-291
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    • 2004
  • To determine the magnetic resonance (MR) imaging findings and natural history of cerebral fat embolism in a cat model, and to correlate the MR imaging and histologic fmdings. Intemel carotid artery of 11 cats was injected with 0.1 ml of triolein. T2-weighted, T1-weighted and Gd-enhanced T1-weighted images were obtained serially for 2 hours, 1 days, 4 days, 1 week, 2 weeks and 3 weeks after embolization. Any abnormal signal intensity was evaluated. After MR imaging at 3 weeks, brain tissue was obtained for light microscopic (LM) examination using hematoxylin-eosin (HE) and Luxol fast blue staining, and for electron microscopic examination. The LM examination with HE staining revealed normal histological findings in the greater part of an embolized lesion. Cystic change was observed in the gray matter of 8 cats, while in the gray and white matter of 3 cats. At LM examination, Luxol fast blue, staining demonstrated demyelination around the cystic change occurring in the white matter, and EM examination of the embolized cortex revealed sporadic intracapillary fat vacuoles (n=11) and disruption of the blood-brain barrier (n=4). Most lesions were normal, however, and perivascular interstitial edema and cellular swelling were mild compared with the control side. The greater part of an embolized lesion showed reversible findings at MR and histological examination. Irreversible focal necrosis was, however, observed in gray and white matter at weeks 3.

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An Experimental Study on the Effects of Hyperthermia and Irradiation on the Rat's Kidney (방사선조사와 온열요법이 백서신에 미치는 조직 변화에 관한 실험적 연구)

  • Yoo, Myung-Hee;Lee, Kyung-Ja;Rhee, Chung-Sik
    • Radiation Oncology Journal
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    • v.7 no.2
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    • pp.157-169
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    • 1989
  • Radiological and clinical evidences indicate that hyperthermia combined with irradiation produce a significant improvement in therapeutic effect of cancer The experiences obtained from 90 rats' kidney A single dose of irradiation ranged from 6Gy, 8Gy and 10Gy was delivered on the rat's kidney. The combined therapy group had the same irradiation after hyperthermia at $42\~44^{\circ}C$ for 30 minutes. Microscopic examination and calculation of thermal enhancement ratio were carried out, and the results were as follows: 1. In the group of hyperthermia alone, there were moderate glomerular congestion and mild tubular degeneration on light microscopic examination. 2. In the group of irradiation alone, tubular degeneration was noted in 6Gy irradiation and its severity was increased along with radiation dose. 3. In the group of hyperthermia combined with irradiation, tubular degeneration and necrosis were appeared in 6Gy and 10Gy irradiation, respectively. 4. On electron microscopic examination, proximal convoluted tubular and glomerular changes in irradiation group were similar to that of combined with hyperthermia, and its severity was increased along with observation periods. 5. Thermal enhancement ratio (TER) was 1.0 after evaluation of histipathologic changes in rat's kidney, with combination therapy.

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Study on the Difference of Urine Sediment Preparation for Microscopic Examination (현미경검사를 위한 요침사 표본제작에 따른 차이 연구)

  • Lee, Hyeok-Jae;Park, Chul;Seo, Min-Young
    • Korean Journal of Clinical Laboratory Science
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    • v.49 no.4
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    • pp.366-373
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    • 2017
  • Urinalysis is considered to be easier and simpler than other tests. It has been known to cause no burden to patients, while offering important information on diagnosing, treating, and determining the prognoses of kidney and urinary tract diseases. Urinary sediments are usually performed by microscopic examination of centrifuged urine by technologist. The guidelines proposed by the Korean Association of External Quality Assessment Service are actually different from those actually practiced by medical institutions and taught to biomedical students in textbooks. Therefore, we verified whether different sediment preparation methods lead different test results. Specimens that tested positive from the occult blood and leukocyte esterase in the urine dipstick test were randomly selected for a microscopic examination. The differences in the urine sediment preparation affected the sediment concentrations, which influenced the cell grade and cell number per HPF. The first factor in determining the sediment concentration is the centrifugal force. Many medical institutions use 1,500 rpm as the centrifugal speed without considering the radius of the centrifuge; such a value may not be accurate for 400 G. Consequently, there were differences in urine concentrations, which influenced the results. The second factor is the amount of sediment in urine. Different amounts of the remaining supernatant led to different sediment concentration factors, again, causing different results. Furthermore, not only by using a pipette to obtain an accurate amount as stipulated, but also by roughly obtaining a drop, the microscopic examination using such a volume of sediment examined affected the results. Therefore, this study highlights the importance of standardization of urine sediment preparation procedures to promote consistency and accuracy across institutions.

Microscopic Identification of the Chinese Patent Medicine 'Geum Ryeo Hwan' (금려환(錦儷丸)의 현미감정 연구)

  • Kim, Jeong-Myo;Park, Jong-Hee
    • Korean Journal of Pharmacognosy
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    • v.37 no.2 s.145
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    • pp.116-119
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    • 2006
  • Geum Ryeo Hwan(錦儷丸) is Chinese patent medicine which has been used for women's diseases and climacteric syndrome in Korea. It consists of 12 kinds of powdered crude drugs. In powdered crude drugs, it is hard to identify each component by chemical analysis or morphological examination. However, the method of identification of powdered crude drugs has not been clearly established. Therefore, it is of interest to establish the microscopic method for identification of powdered crude drugs of Chinese patent medicines. The effectiveness of microscopic method is exemplified by the identification of tissue and contents of crude drugs by comparison with standard drugs. Moreover, this method has advantage as a microscale analysis, since it requires only a small amount of specimens. In this study, it is demonstrated that the microscopic method is very effective for the identification of 12 crude drug ingredients in Geum Ryeo Hwan.

Microscopic Identification of the Chinese Patent Medicine 'Ah Myeong Dan' (아명단(兒明丹)의 현미감정연구)

  • Kim, Jeong-Myo;Park, Jong-Hee
    • Korean Journal of Pharmacognosy
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    • v.36 no.3 s.142
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    • pp.205-208
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    • 2005
  • Ah Myeong Dan (兒明丹) is Chinese patent medicine which is used for congenital fever and congenital boils in Korea. It consists of 11 kinds of powdered crude drugs. In powdered crude drugs, it is hard to identify each component by chemical analysis or morphological examination. However, the method of identification of powdered crude drugs has not been clearly established. Therefore, it is of interest to establish the microscopic method for identification of powdered crude drugs of Chinese patent medicines. The effectiveness of microscopic method is exemplified by the identification of tissue and contents of crude drugs by comparison with standard drugs. In this study, it is demonstrated that the microscopic method is very effective for the identification of 11 crude drug ingredients in Ah Myeong Dan.

A Study on the Defaulters of Tuberculosis Patient Registered at Health Center in Kyongnam Area (보건소 등록결핵환자중 중단자에 관한 조사연구)

  • Kim, Yong-Joon
    • Journal of agricultural medicine and community health
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    • v.6 no.1
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    • pp.73-81
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    • 1981
  • This study was designed to analyze the result of Tb worker's activities on the performance of follow up program as part of the government tuberculosis program. The specific objectives of this study was also to improve the method of managing the patient who were registered at health center by the setting the priorities depend upon in their results of sputum examination and X-ray examination. All the medical records of 509 patients who were dropped out from government health center in Kyongnam area during 1978, were analyzed and interpreted. Followings are the result of the study. 1. The number of investigated cases were 509 (356% males and 153 females), by age the most prevalent group was 20~29 year old group as 27.3% and 20~40 year old group was 61.5%, above 61 year old was 14.9%. 2. The microscopic result of their sputum was positive in 52.1%, and by X-ray examination moderate advanced case was 63.9% minimal 18.5% and far advanced 17.6% in order. 3. Average duration of treatment was 9.03 months, 11.4 months in microscopic positive cases and 6.5 months in negative cases. 4. Conversion rate of microscopic positive case was 42.9% on sputum culture, in the negative cases, it was confirmed in negative 20.1% only by the initial sputum culture. 5. The rate who get take X-ray and sputum examination among any family member of the patients was 43.4% in positive cases, 20.9% in negative cases. 6. 80.2% of positive cases took X-ray for following up in every 6 month after registration, 41.0% in negative cases. 7. Defaulting reasons which recorded in individual card were undetermined reason (42.0%), treating elswhere (22. 4%), refused treatment (17.9%) and moved out (17.7%).

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Risk Factors of Microscopic Invasion in Early Gastric Cancer

  • Choi, Jong-Ho;Suh, Yun-Suhk;Park, Shin-Hoo;Kong, Seong-Ho;Lee, Hyuk-Joon;Kim, Woo Ho;Yang, Han-Kwang
    • Journal of Gastric Cancer
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    • v.17 no.4
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    • pp.331-341
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    • 2017
  • Purpose: This study aimed to evaluate the clinical significance of microscopic invasion to determine the adequate resection margin in early gastric cancer (EGC). Materials and Methods: A retrospective review was performed that included patients who underwent gastrectomy for clinical early gastric cancer (cEGC) at Seoul National University Hospital between January 2007 and December 2010. After subtracting the microscopic resection margin from the gross resection margin for each proximal or distal resection margin, microscopic invasion was represented by the larger value. Microscopic invasion and its risk factors were analyzed according to the clinicopathologic characteristics. Results: In total, 861 patients were enrolled in the study. Microscopic invasion of cEGC was $6.0{\pm}12.8mm$, and the proportion of patients with microscopic invasion ${\geq}0mm$ was 78.4%. In the risk group, tumor location, pT stage, and differentiation did not significantly discriminate the presence of microscopic invasion. The microscopic invasion of EGC-IIb was $13.9{\pm}16.8mm$, which was significantly greater than that of EGC-I. No linear correlation was observed between the overall tumor size and microscopic invasion (R=0.030). The independent risk factors for microscopic invasion ${\geq}20mm$ were EGC-IIb vs. EGC-I/IIa/IIc/III (odds ratio [OR], 3.103; 95% confidence interval [CI], 1.533-6.282; P=0.002) and male vs. female sex (OR, 1.655; 95% CI, 1.012-2.705; P=0.045). Conclusions: Male sex and EGC-IIb were independent risk factors for microscopic invasion ${\geq}20mm$. Examination of intraoperative frozen sections is highly recommended to avoid resection margin involvement, especially in cases of EGC-IIb.

Microscopic Identification of the Chinese Patent Medicine "Shin Kwae Hwan" (신쾌환의 현미감정연구)

  • Jung, Ji-Hyun;Kim, Seong-Ryong;Park, Jong-Hee
    • Korean Journal of Pharmacognosy
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    • v.39 no.4
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    • pp.330-334
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    • 2008
  • Shin Kwae Hwan(神快丸) is a Chinese patent medicine which has been used for polymyositis, trigeminal neuralgiaand ischiodynia in Korea. It consists of 15 kinds of powdered crude drugs. In powered crude drugs, it is hard to identify each component by chemical analysis or morphological examination. However, the method of identification of powdered crude drugs has not been clearly established. For the identification of individual crude drugs in such powdery mixtures, microscopic method may advantageously be used, as it requires only small amount of specimens. In this study, it is demonstrated that the microscopic method is very effective for the identification of 15 crude drug ingredients in Shin Kwae Hwan.

Microscopic Identification of the Chinese Patent Medicine 'An Che Whan' (안체환의 현미감정연구)

  • Kim, Jeong-Myo;Kim, Seong-Ryung;Park, Jong-Hee
    • Korean Journal of Pharmacognosy
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    • v.37 no.3
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    • pp.196-199
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    • 2006
  • 'An Che Whan(安滯九)' is a Chinese patent medicine which has been used for gastric ulcer and digestive disorder in Korea. It consists of 15 kinds of powdered crude drugs. In powdered crude drugs, it is hard to identify each component by chemical analysis or morphological examination. However, the method of identification of powdered crude drugs has not been clearly established. For the identification of individual crude drugs in such powdery mixtures, a microscopic method may be used conveniently as it requires only a small amount of specimens. In this study, it is demonstrated that the microscopic method is very effective fer the identification of the 15 crude drug ingredients in An Che Whan.