• Title/Summary/Keyword: micro package

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Investigation of Impacts of Truck Lane Restrictions on Multilane Highways Using Micro Traffic Simulation (미시적 시뮬레이션을 이용한 화물차 차로이용제한 영향분석)

  • Yang, Choong-Heon;Son, Young-Tae;Kwon, Yong-Suk
    • International Journal of Highway Engineering
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    • v.9 no.4
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    • pp.75-82
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    • 2007
  • This study was performed to investigate impacts of truck lane restrictions on multilane highways on traffic flow variables such as average speed, the frequency of lane changes, and change in traffic volume and also to verify whether or not different lane restriction scenarios were proper. Two types of hypothetical highway networks and OD demands were developed for traffic simulation models in order to conduct the experimental study. Three types of scenarios were also developed according to the number of restricted lanes for trucks. The PARAMICS microscopic traffic simulation software package was used as the primary analytical tool. Statistical analysis was conducted with simulation outputs. Results showed that truck lane restrictions may lead to positive impacts on traffic flow on multilane highways. In addition, this study demonstrated that the number of restricted lanes can be very an important factor to lead successful implementation of truck lane restrictions.

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Identification of novel potential drugs and miRNAs biomarkers in lung cancer based on gene co-expression network analysis

  • Sara Hajipour;Sayed Mostafa Hosseini;Shiva Irani;Mahmood Tavallaie
    • Genomics & Informatics
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    • v.21 no.3
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    • pp.38.1-38.8
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    • 2023
  • Non-small cell lung cancer (NSCLC) is an important cause of cancer-associated deaths worldwide. Therefore, the exact molecular mechanisms of NSCLC are unidentified. The present investigation aims to identify the miRNAs with predictive value in NSCLC. The two datasets were downloaded from the Gene Expression Omnibus (GEO) database. Differentially expressed miRNAs (DEmiRNA) and mRNAs (DEmRNA) were selected from the normalized data. Next, miRNA-mRNA interactions were determined. Then, co-expression network analysis was completed using the WGCNA package in R software. The co-expression network between DEmiRNAs and DEmRNAs was calculated to prioritize the miRNAs. Next, the enrichment analysis was performed for DEmiRNA and DEmRNA. Finally, the drug-gene interaction network was constructed by importing the gene list to dgidb database. A total of 3,033 differentially expressed genes and 58 DEmiRNA were recognized from two datasets. The co-expression network analysis was utilized to build a gene co- expression network. Next, four modules were selected based on the Zsummary score. In the next step, a bipartite miRNA-gene network was constructed and hub miRNAs (let-7a-2-3p, let-7d-5p, let-7b-5p, let-7a-5p, and let-7b-3p) were selected. Finally, a drug-gene network was constructed while SUNITINIB, MEDROXYPROGESTERONE ACETATE, DOFETILIDE, HALOPERIDOL, and CALCITRIOL drugs were recognized as a beneficial drug in NSCLC. The hub miRNAs and repurposed drugs may act a vital role in NSCLC progression and treatment, respectively; however, these results must validate in further clinical and experimental assessments.

Fabrication of Porous Cellulose Acetate Propionate/Polybutylene Succinate Microfibers by High Speed Centrifugal Spinning (초고속 원심방사에 의한 아세트산프로피온산 셀룰로오스/폴리부틸렌 숙시네이트 다공성 마이크론 섬유 제조)

  • Tae Young Kim;Mi Kyung Kim;Jinsoo Kim;Jungeon Lee;Jae Hoon Jung;Youngkwon Kim;Tae Hyeon Kim;Ki Young Kim;Jeong Hyun Yeum
    • Textile Coloration and Finishing
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    • v.35 no.4
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    • pp.239-245
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    • 2023
  • Cellulose is an abundant biodegradable material in nature with excellent properties, but due to its poor processability, it has been widely studied for processing through modification. Cellulose acetate propionate (CAP) is a cellulose derivative in which the hydroxyl group of cellulose is replaced by acetyl and propionyl groups. CAP has several advantages, such as excellent solubility, structural stability, light and weather resistance, and good transparency. Porous nanofibers with excellent specific surface area, which can be applied in various fields, can be easily formed by the phase separation method using highly volatile solvents. High speed centrifugal spinning is a nano/micro fiber preparation method with advantages such as fast spinning and easy alignment control. In this study, a CAP/polybutylene succinate (PBS) spinning solution with chloroform as solvent was prepared to prepare porous microfibers and the fiber morphology was examined as a function of the disk rotation speed in an high speed centrifugal spinning device.

Prediction of field failure rate using data mining in the Automotive semiconductor (데이터 마이닝 기법을 이용한 차량용 반도체의 불량률 예측 연구)

  • Yun, Gyungsik;Jung, Hee-Won;Park, Seungbum
    • Journal of Technology Innovation
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    • v.26 no.3
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    • pp.37-68
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    • 2018
  • Since the 20th century, automobiles, which are the most common means of transportation, have been evolving as the use of electronic control devices and automotive semiconductors increases dramatically. Automotive semiconductors are a key component in automotive electronic control devices and are used to provide stability, efficiency of fuel use, and stability of operation to consumers. For example, automotive semiconductors include engines control, technologies for managing electric motors, transmission control units, hybrid vehicle control, start/stop systems, electronic motor control, automotive radar and LIDAR, smart head lamps, head-up displays, lane keeping systems. As such, semiconductors are being applied to almost all electronic control devices that make up an automobile, and they are creating more effects than simply combining mechanical devices. Since automotive semiconductors have a high data rate basically, a microprocessor unit is being used instead of a micro control unit. For example, semiconductors based on ARM processors are being used in telematics, audio/video multi-medias and navigation. Automotive semiconductors require characteristics such as high reliability, durability and long-term supply, considering the period of use of the automobile for more than 10 years. The reliability of automotive semiconductors is directly linked to the safety of automobiles. The semiconductor industry uses JEDEC and AEC standards to evaluate the reliability of automotive semiconductors. In addition, the life expectancy of the product is estimated at the early stage of development and at the early stage of mass production by using the reliability test method and results that are presented as standard in the automobile industry. However, there are limitations in predicting the failure rate caused by various parameters such as customer's various conditions of use and usage time. To overcome these limitations, much research has been done in academia and industry. Among them, researches using data mining techniques have been carried out in many semiconductor fields, but application and research on automotive semiconductors have not yet been studied. In this regard, this study investigates the relationship between data generated during semiconductor assembly and package test process by using data mining technique, and uses data mining technique suitable for predicting potential failure rate using customer bad data.

A Study on the Establishment of Optimal Transportation Networks in Busan New Port (부산항 신항 최적의 교통망 수립에 관한 연구)

  • Park, Ho-Kyo;Choi, Yang-Won
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.37 no.1
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    • pp.125-132
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    • 2017
  • The development project of Busan New Port aims to be Logistics Hub Port but there are too many things to deal with ; enlargement of harbour, interport competition, modernization of harbour loading equipment and so on. At present, 23 berths of North and South container quay are in operation and 22 berths will be constructed on west and south-side by 2020. Namely, Busan New Port will operate 45 berths in 2020. When it comes to port distripark, a large-scale of Port distripark project is underway, such as Ung-Dong district 1,2 phase, West container 1,2phase, North distripark and so on. This study is to deduce traffic system problem of Busan New Port which is caused by the development project through predicting traffic need considering the development project. According to study, there are three main problems of traffic system : 1. traffic congestion caused on main crossroad, connecting second harbour back road. 2. It has been predicted that South-North road and traffic capacity of New Port road would lack compared to traffic volume-to-be-increased. Moreover, the detour volume of traffic is caused because New Port's 1st avenue and route 2 were not connected directly. Thus, this study suggests three kinds of improvement plan for smoother traffic flow. 1st. Operate roundabout on major intersection, for example, second harbour back road, west container wharf's subway corridors(South to North), and permit only right turn on sub-intersection. 2nd. Extend New Port road(North container's port road) by utilizing side walk and median. 3rd. Install exit ramp which utilizes Route 2 connecting New Port's 1st avenue and local road 1042. The method we used to analyze the effect of improvement is Vissim of Mircro Simulation Package.

Fabrication of MEMS Test Socket for BGA IC Packages (MEMS 공정을 이용한 BGA IC 패키지용 테스트 소켓의 제작)

  • Kim, Sang-Won;Cho, Chan-Seob;Nam, Jae-Woo;Kim, Bong-Hwan;Lee, Jong-Hyun
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.47 no.11
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    • pp.1-5
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    • 2010
  • We developed a novel micro-electro mechanical systems (MEMS) test socket using silicon on insulator (SOI) substrate with the cantilever array structure. We designed the round shaped cantilevers with the maximum length of $350{\mu}m$, the maximum width of $200{\mu}m$ and the thickness of $10{\mu}m$ for $650{\mu}m$ pitch for 8 mm x 8 mm area and 121 balls square ball grid array (BGA) packages. The MEMS test socket was fabricated by MEMS technology using metal lift off process and deep reactive ion etching (DRIE) silicon etcher and so on. The MEMS test socket has a simple structure, low production cost, fine pitch, high pin count and rapid prototyping. We verified the performances of the MEMS test sockets such as deflection as a function of the applied force, path resistance between the cantilever and the metal pad and the contact resistance. Fabricated cantilever has 1.3 gf (gram force) at $90{\mu}m$ deflection. Total path resistance was less than $17{\Omega}$. The contact resistance was approximately from 0.7 to $0.75{\Omega}$ for all cantilevers. Therefore the test socket is suitable for BGA integrated circuit (IC) packages tests.

Quality Changes of Fresh-Cut Tumeric by Packaging Methods during Storage (포장방법에 따른 세절 생울금의 저장 중 품질 변화)

  • Kim, Dong-Hoo;Han, Jin-Soo;Woo, In-Bong;Jung, Jun-Jae;Park, Si-Woo;Heo, Kyung-Chel;Ha, Ju-hyeung;Yoon, Chan-Suk
    • KOREAN JOURNAL OF PACKAGING SCIENCE & TECHNOLOGY
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    • v.23 no.3
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    • pp.151-162
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    • 2017
  • The purpose of this study was to investigate the quality change of fresh-cut tumeric (Curcuma Longa Linne) according to packaging method during storage time. The fresh-cut tumeric were packaged in three different methods : degassing valve packaging (DVP), $CO_2$ gas absorber packaging (CAP) and micro-perforated packaging (MPP). After the samples were packaged, they were stored for 15 days at 4 and $23^{\circ}C$ respectively. The following parameters were observed to indicate the quality changes of the samples: weight loss, CIE $L^*a^*b^*$ colour difference, variation of gas composition inside the package, curcumin contents and changes in hardness of fresh-cut tumeric. DVP did not effectively release $CO_2$ gas to the outside. MPP was suitable to release $CO_2$ gas. However, MPP showed very fast browning and erosion, because a large amount of oxygen was introduced through the perforated hole on the film. CAP was most effective packaging method to inhibit browning, to prevent expansion of the packaging by $CO_2$ gas and to minimize weight loss of fresh-cut tumeric.

Determination of Minimum Spacing between Off-ramp Terminus and Intersection Considering the Influence of Adjacent Signalized Intersections (신호교차로 영향에 따른 도시고속도로 유출연결로 최소이격거리에 관한 연구)

  • Kim, Sang-Gu;Sim, Dae-Yeong;Heo, Du-Wan
    • Journal of Korean Society of Transportation
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    • v.25 no.4
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    • pp.79-87
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    • 2007
  • The interchanges of urban freeways have many problems with traffic operation due to high off-ramp flows and frequent congestion at adjacent intersections. The flow exiting from off-ramps is affected by the operational status and traffic volume conditions of the nearest signalized intersection. As a result, off-ramp flow cannot exit and the queue backs up the freeway mainline when queues from the signalized intersection form up to the junction of the off-ramp and street. The spacing between an off-ramp and an adjacent intersection is likely to determine the traffic conditions at the adjacent intersection. However, the current design guidelines do not consider such a factor. This study is to develop a model calculating the spacing between off-ramps and adjacent intersections considering the signal, traffic, and road conditions. The variables affecting the model in this study are effective green time (g/C), volume-capacity ratio (v/c), the number of lanes, and off-ramp volume. Various scenarios are designed to represent the effects of the variables and the road networks are constructed using VISSIM, which is a common traffic micro-simulation software package. The queue length is derived from VISSIM and this length is considered as the recommended spacing between the off-ramp and the adjacent intersection. Through the simulation analysis, regression models are developed to calculate the queue length reflecting the various conditions such as signals, traffic, and road configurations. The developed model can be used to create road design guidelines to determine the location of off-ramps in the planning stage.

Effects of OTR Film Type on the Quality of Lepidium sativum L. Baby Leaf Vegetable during MA Storage (큰다닥냉이 어린잎채소의 MA저장 중 OTR 필름 종류가 품질에 미치는 영향)

  • Kim, Ju Young;Han, Su Jeong;Choi, In-Lee;Yoon, Jae Su;Moon, Young Hyun;Kim, Sang Min;Kang, Ho-Min
    • Journal of Bio-Environment Control
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    • v.27 no.2
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    • pp.180-184
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    • 2018
  • This study was conducted to examine the effect OTR film type on the quality of garden cress (Lepidium sativum L.) baby leaf during MA storage. Garden cress harvested at baby leaf size of 10cm plant height packed with 1,300 cc, 10,000 cc, 20,000 cc, 40,000 cc, and $80,000cc{\cdot}m^{-2}{\cdot}day^{-1}{\cdot}atm^{-1}$ OTR (oxygen transmission rate) films and MP (micro-perforated) film, and then stored at $8^{\circ}C$ for 10 days. All of the OTR film treatments showed a decrease of 0.5% fresh weight until the storage end date and a 1.3% decrease in the MP film treatment. The oxygen concentration in the packaging during storage was maintained at 18% or more in 20,000 cc, 40,000 cc, and 80,000 cc OTR film treatments, while the 1,300 cc OTR film treatment decreased to 11% at the storage end date. And the concentration of carbon dioxide was steadily increased in the 1,300 cc and 10,000 cc OTR film treatments to show the levels of 4.5% and 3.4%, respectively, and the other OTR film treatments showed a concentration of less than 1%. Ethylene concentration in the package was maintained at the highest level of $3-5{\mu}L{\cdot}L^{-1}$ in the 1,300 cc treatment during the storage period. The lowest odor and the highest quality of appearance were observed in the 1,300 cc treatment, but the MP film treatment and the other OTR treatments lost marketable quality due to yellowing. The color of garden cress baby leaf was changed the lowest in 1,300 cc treatment that showed the highest chlorophyll content and Hue angle value, lowest $b^*$ value, present of yellowing at end of storage date. Therefore, 1,300 cc treatment which was most effective for yellowing and odor suppression during storage is considered to be suitable for packaging of garden cress baby leaf.

Effect of Packaging Systems with High CO2 Treatment on the Quality Changes of Fig (Ficus carica L) during Storage (저장 중 무화과(Ficus carica L) 선도유지를 위한 고농도 이산화탄소 처리된 포장 시스템 적용 연구)

  • Kim, Jung-Soo;Chung, Dae-Sung;Lee, Youn Suk
    • Food Science and Preservation
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    • v.19 no.6
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    • pp.799-806
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    • 2012
  • This experiment was conducted to establish the optimum conditions for high $CO_2$ gas treatment in combination with a proper gas-permeable packaging film to maintain the quality of fig fruit (Ficus carica L). Among the fig fruits with different high $CO_2$ treatments, the quality change was most effectively controlled during storage in the 70%-$CO_2$-treated fig fruit. Harvested fig fruit was packaged using microperforated oriented polypropylene (MP) film to maintain the optimum gas concentrations in the headspace of packaging for the modified-atmosphere system. MP film had an oxygen transmission rate of about $10,295cm^3/m^2$/day/atm at $25^{\circ}C$. The weight loss, firmness, soluble-solid content (SSC), acidity (pH), skin color (Hunter L, a, b), and decay ratio of the fig fruits were monitored during storage at 5 and $25^{\circ}C$. The results of this study showed that the OPP film, OPP film + 70% $CO_2$, and MP film+70% $CO_2$ were highly effective in reducing the loss rate, firmness and decay occurrence rate of fig fruits that were packaged with them during storage. In the case of using treatments with packages of OPP film and OPP film+70% $CO_2$, however, adverse effects like package bursting or physiological injury of the fig may occur due to the gas pressure or long exposure to $CO_2$. Therefore, the results indicated that MP film containing 70% $CO_2$ can be used as an effective treatment to extend the freshness of fig fruits for storage at a proper low temperature.