• 한국생물공학회:학술대회논문집
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• 2003.10a
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• pp.717-720
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• 2003

A chromogenic biosensor employing microfluidics on a chip has been developed for the determination of high-density lipoprotein (HDL) cholesterol (HDL-C) in human serum. We have investigated a plain and effective method to immobilize enzymes within the microchip without chemically modifying micro-channel or technically micro-fabricating column reactor and fluid channel network. In assessing risk factors of coronary heart disease, a micro-chip system would minimize requirements of instrument and reagent handling.

• 유체기계공업학회:학술대회논문집
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• 2006.08a
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• pp.249-252
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• 2006

We conducted the experiment to analyze characteristics of micro-nozzle using different cold gas under two different nozzle expansion ratios in low vacuum condition. We measured thrust and chamber pressure and mass flow rate under low vacuum condition, and then compared them with those in ambient pressure.

• 유체기계공업학회:학술대회논문집
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• 2004.12a
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• pp.743-747
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• 2004

In this study, micro blood separators capable of separating blood cell and blood plasma using microstructure are fabricated and their feasibility and separation performance are evaluated. Test results show the possibility of separating blood cell and blood plasma using microstructure. To improve separation performance and anti-clogging characteristic, technical points of tested micro blood separators are discussed and improved designs are presented.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.38 no.5
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• pp.567-573
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• 2014

Since the development of microelectromechanical systems (MEMS) technology for the medical field, various micro-fluid transfer systems have been studied. This paper proposes a micro-piezoelectric pump that imitates a stomach's peristalsis by using two separate piezoelectric elements, in contrast to existing micro-pumps. This piezoelectric pump is operated by using the valve-less traveling wave of peristalsis movement. If the piezoelectric plates at the two separated plates are actuated at the input voltage, a traveling wave occurs between the two plates. Then, the fluid migrates by the pressure difference generated by the traveling wave. Finite element analysis was performed to understand the mechanics of the combined system with piezoelectric elements, elastic structures, and fluids. The effects of design variables such as the chamber height and number of ceramics on the flow rate of the fluid were examined.

• Proceedings of the KSME Conference
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• 2001.06c
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• pp.47-52
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• 2001

Micro-injection molding and microfluidic devices with the help of MEMS technologies including the LIGA process are expected to play important roles in. micro-system industries, in particular the bioapplication industry, in the near future. Understanding fluid flows in micro-channels is important since micro-channels are typical geometry in various microfluidic devices and mold inserts for micro-injection molding. In the present study, both experimental and numerical studies have been carried out to understand the detailed flow phenomena in micro-channel filling process. Three sets of micro-channels of different thickness were fabricated and a flow visualization system was also developed to observe the filling flow into the micro-channels. Experimental flow observations were extensively made to find the effects of channel width and thickness, and effects of surface tension and volume flow rate and so on. And a numerical analysis system has been developed to simulate the filling flow into micro-channels with the surface tension effect taken into account. Discussed are the flow visualization experimental observations along with the predictability of the numerical analysis system.

• Journal of Korean Association for Spatial Structures
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• v.22 no.4
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• pp.15-22
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• 2022

Micro-climate measurements and computational fluid analysis were conducted to use it as basic data for the preservation and management of the old house of Kim Myung-kwan, a traditional building that is National Folk Cultural Property No. 26. As a result of the actual measurement, the temperature and humidity are relatively evenly distributed indoors unlike outdoors, but the temperature and humidity vary depending on the time change and the installation location in the outdoors. It was found that the temperature increases after dawn and the temperature varies depending on the installation position around 14:00-15:00, when the temperature becomes the highest. In particular, the temperature was high at the outdoor measurement point adjacent to the building and the fence. As a result of the computational fluid analysis, the temperature was high in the buildings and fences in the old house or in the area adjacent to the building, and it was about 1℃ higher than the surrounding area. In this area, it is judged that the thickening of wood will occur more severely than in other locations, and special preservation management is required.

• Journal of the Korean Society of Visualization
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• v.11 no.1
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• pp.7-13
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• 2013

• Transactions of the Korean Society of Mechanical Engineers B
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• v.23 no.8
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• pp.969-977
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• 1999

A similarity solution of a steady laminar flow of micropolar fluids past wedges has been studied. The similarity variables found by Falkner and Skan are employed to reduce the streamwise-dependence in the coupled nonlinear boundary layer equations. Numerical solutions of the equations are then obtained using the fourth-order Runge-Kutta method and the distribution of velocity, micro-rotation, shear and couple stress across the boundary layer are obtained. These results are compared with the corresponding flow problems for Newtonian fluid past wedges with various wedge angles. Numerical results show that, keeping ${\beta}$ constant, the skin friction coefficient is lower for a micropolar fluid, as compared to a Newtonian fluid. For the case of constant material parameter K, however, the velocity distribution for a micropolar fluid is higher than that of a Newtonian fluid.

• 유체기계공업학회:학술대회논문집
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• 2002.12a
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• pp.473-476
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• 2002

Micro turbine that is a component of micro power system refers to turbines on the scale of centimeters which can transmit power on the order of tens of Watts. Such devices can be used as propulsion or power generation devices for various potable and micro devices. An interdisciplinary team at Seoul National University has designed, fabricated and tested such a device, and this paper describes test results.

• Journal of Biomedical Engineering Research
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• v.14 no.4
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• pp.349-354
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• 1993

To investigate the relations between the physical constitutions, the acid-base balance, and the autonomic nervous function, the blood gas, the heart rate and the concentrations of Na, K of serum were measured pre-and poststimulation. As the result, it is shown that in the normal condition the macro-negative(strong liver- weak lung type) is the metabolic alkalosis, the macro-positive (strong lung-weak liver type) is the metabolic acidosis, the micro-negative(strong kidney-weak spleen type) is the alkalosis and the micro-positive (strong spleen-weak kidney type) is the acidosis. And the ntacro-positive and micro-positive are the sympathetic lead, the macro-negative and micro-negative are the parasympathetic lead. In the macro-positive and micro-positive subjects, the concentration of K in serum is relatively high. This si coincided with the acidosis. But in the macro-negative and micro-negative subjects, the concentration of K in serum is relatively low. This is coincided with the alkalosis.