• 제목/요약/키워드: methods: n-body

검색결과 1,061건 처리시간 0.032초

Effects of aged garlic extract and endurance exercise on skeletal muscle FNDC-5 and circulating irisin in high-fat-diet rat models

  • Seo, Dae Yun;Kwak, Hyo Bum;Lee, Sung Ryul;Cho, Yeun Suk;Song, In-Sung;Kim, Nari;Bang, Hyun Seok;Rhee, Byoung Doo;Ko, Kyung Soo;Park, Byung Joo;Han, Jin
    • Nutrition Research and Practice
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    • 제8권2호
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    • pp.177-182
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    • 2014
  • BACKGROUND/OBJECTIVES: Irisin, a newly identified hormone, is associated with energy homeostasis. We investigated whether aged garlic extract (AGE) and exercise training intervention could improve body weight, insulin sensitivity, skeletal muscle fibronectin domain containing protein 5 (FNDC-5) levels, and plasma irisin in high-fat diet (HFD). MATERIALS/METHODS: Male Sprague Dawley rats were fed a ND (normal diet, n=5) or HFD (n=28) for 6 weeks. After 6 weeks, all rats were divided into 5 groups for the next 4 weeks: ND, (normal diet, n=5), HFD (high-fat diet, n=7), HFDA (high-fat diet + aged garlic extract, n=7), HFDE (high-fat diet + exercise, n=7), and HFDEA (high-fat diet + exercise + aged garlic extract, n=7). Exercise groups performed treadmill exercises for 15-60 min, 5 days/week, and AGE groups received AGE (2.86 g/kg, orally injected) for 4 weeks. RESULTS: Significant decreases in body weight were observed in the ND, HFDE, and HFDEA groups, as compared with the HFD group. Neither intervention affected the masses of the gastrocnemius muscle or liver. There were no significant differences in glucose levels across the groups. The homeostatic model assessments of insulin resistance were significantly higher in the HFD group, as compared with the ND, HFDA, HFDE, and HFDEA groups. However, skeletal muscle FNDC-5 levels and plasma irisin concentrations were unaffected by AGE or exercise in obese rats. AGE supplementation and exercise training did not affect skeletal muscle FNDC-5 or plasma irisin, which are associated with insulin sensitivity in obese rats. CONCLUSION: Our results suggest that the protection against HFD-induced increases in body fat/weight and insulin resistance that are provided by AGE supplementation and exercise training may not be mediated by the regulation of FNDC-5 or irisin.

하악 시상골 절단술 후 고정 방법에 따른 회귀 성향에 대한 비교 연구 (Comparative Study of Skeletal Relapse According to the Fixation Method after BSSRO for Mandibular Setback.)

  • 배진오;이동근;오승환;신기영;장관식
    • Maxillofacial Plastic and Reconstructive Surgery
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    • 제22권2호
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    • pp.184-190
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    • 2000
  • Objective : To compare two different methods of rigid fixation in postoperative stability after mandibular setback. Material and Methods : 28 patients with Class III malocclusion were treated by bilateral sagittal split ramus osteotomy(BSSRO) and mandibular setback were selected for this study. Group A(n=14) had the bone segments fixed with monocortical miniplate on the lateral side of the mandibular body and Group B(n=14) had three noncompressive bicortical screw inserted at the genial area through a transcutaneous approach. Cephalograms were taken preoperatively, postoperatively within 1 weeks and at a follow-up period (mean 8.9 months after surgery) and the amount of setback and postoperative change were measured. Results : Postoperative relapse between two groups was minimal in setback of the mandible. Statistical analysis showed no significant difference in postoperative relapse. Conclusion : This study suggests that both methods of skeletal fixation investigated give comparable postoperative stability and their use in mandibular setback appears to be a fairly stable clinical procedure .

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SIMULATIONS OF THE INTERACTING MAGELLANIC SYSTEM

  • GARDINER LANCE T.;NOGUCHI MASAFUMI
    • 천문학회지
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    • 제29권spc1호
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    • pp.93-94
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    • 1996
  • The Galaxy and the Large and Small Magellanic Clouds (LMC and SMC respectively) form a triple system of mutually interacting galaxies. We have carried out a set of N-body simulations on the gravitational interaction of the SMC with the Galaxy and the LMC in order to model prominent features such as the Magellanic Stream, the inter-Cloud Bridge, and the large depth of the SMC which are thought to be products of the tidal interactions among the members of this system.

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TRIBOLOGY:STATE OF THE ART AND ADVANCES IN CIS

  • Myshkin, N.K.
    • 한국윤활학회:학술대회논문집
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    • 한국윤활학회 1993년도 제18회 학술대회 초록집
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    • pp.1-31
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    • 1993
  • General state of research in fundamentals and applied areas of tribology is analysed with taldng account of changes in structure of funding and other aspects of transfer from centmllzed state economy to market one under simultaneous effect of USSR disintegration to independent states. Belarus Tribology Society as a coordinating body is presented. Activities of the major centers of research in friction, wear and lubrication are shown. Recent advances in development of analytical and calculation methods, surface characterization, wear testing and standardization, condition monitoring and tribomaterials are considered.

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척추 수술에 사용되는 나사못의 반복 삽입과 인출이 인장항력에 미치는 영향 : 생체 역학적 연구 (The Effect of Repetitive Insertion and Pullout of Spinal Screws on Pullout Resistance : A Biomechanical Study)

  • 백광흠;;김광진;김재민;김충현
    • Journal of Korean Neurosurgical Society
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    • 제30권2호
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    • pp.131-136
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    • 2001
  • 목적 : 최근 척추 수술에 나사못을 사용하는 빈도와 범위가 넓어 지고 있는데 때로 수술 중 한번 삽입하였던 나사못을 다시 사용하는 경우가 있다. 인체 골과 타이타늄의 탄성계수가 크게 차이 나지만 반복 삽입 과정에서 나사못의 이가 손상될 가능성이 있다. 저자들은 나사못의 반복 삽입이 나사못의 인출 저항에 미치는 영향을 조사하였다. 방법 : 각각 6개의 세가지 다른 종류 cortical lateral mass screw, cancellous lateral mass screw and cervical vertebral body screw의 나사못을 시험하였다. 나사못을 인체의 골과 비슷한 밀도의 인공합성골에 삽입하였으며 삽입 중 삽입력을 측정하였고 그 후 Instron(Model TT-D, Canton, MA)을 이용하여 2.4mm의 속도로 인출하여 인장항력을 digital oscilloscope에 기록하였다. 위의 과정을 3회 반복하여 기록한 뒤 나사못을 광학 현미경으로 확대하여 관찰하였다. 결과 : cortical lateral mass screws의 평균 인장항력(1회인장 시험 $185.66N{\pm}42.60$, 2회 인장시험 $167.10N{\pm}27.01$, 3회인장 시험 $162.52N{\pm}23.83$ : p=0.03)과 cervical vertebral body screws ($386.0N{\pm}24.1$, $360.2N{\pm}17.5$ and $330.9N{\pm}16.7$ : p=0.0024)은 반복하여 삽입, 인장 검사 할 때 마다 감소하였으나 cancellous lateral mass screws의 평균 인장항력($194.00N{\pm}36.47$, $219.24N{\pm}26.58$ and $199.49N{\pm}36.63$ : p=0.24)은 감소하지 않았다. 전자현미경 소견에서 나사이의 끝이 무디어지고 표면이 문드러진 것을 관찰할 수 있었다. 결론 : 일부 나사못을 반복하여 삽입한 후 나사못의 인장항력이 감소되었으므로 수술중 여러번 삽입하였던 나사못은 최종 구조물에 사용되지 않아야 한다.

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Indications and findings of flexible bronchoscopy in trauma field in Korea: a case series

  • Dongsub Noh
    • Journal of Trauma and Injury
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    • 제36권3호
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    • pp.206-209
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    • 2023
  • Purpose: Since its implementation, flexible fiberoptic bronchoscopy (FBS) has played an important role in the diagnosis and treatment of tracheobronchial tree and pulmonary disease. Although FBS is often performed by endoscopists, it has also been performed by surgeons, albeit rarely. This study investigated FBS from the surgeon's perspective. Methods: This retrospective study included patients who underwent FBS performed by a single thoracic surgeon between March 2017 and December 2021. Accordingly, the epidemiology, purpose, results, and complications of FBS were analyzed. Results: A total of 47 patients received FBS, whereas 13 patients underwent repeat FBS. Their mean age was 60.7 years. The main organs injured involved the chest (n=22), brain (n=9), abdominal organ (n=7), cervical spine (n=4), extremities (n=4), and face (n=1). The average Injury Severity Score was 22.5. Indications for FBS included atelectasis or haziness on chest x-ray (n=34), pneumonia (n=17), difficult ventilator management (n=7), percutaneous dilatory tracheostomy (n=3), blood aspiration (n=2), foreign body removal (n=2), and intubation due to a difficult airway (n=1). The findings of FBS were mucous plugs (n=36), blood and blood clots (n=16), percutaneous dilatory tracheostomy (n=3), foreign bodies (n=2), granulation tissue at the tracheostomy site (n=2), tracheostomy tube malposition (n=1), bronchus spasm (n=1), difficult airway intubation (n=1), and negative findings (n=5). None of the patients developed complications. Conclusions: FBS is an important modality in the trauma field that allows for the possibility of diagnosis and therapy. With sufficient practice, surgeons may safely perform FBS at the bedside with relative ease.

Effects of ᴅ-allulose on body fat accumulation in rats fed severely carbohydrate-restricted diets containing beef tallow or soybean oil

  • Tatsuhiro Matsuo;Shunsuke Higaki;Reiko Inai;Susumu Mochizuki;Akihide Yoshihara;Kazuya Akimitsu
    • Journal of Nutrition and Health
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    • 제57권2호
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    • pp.185-195
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    • 2024
  • Purpose: The carbohydrate-restricted diet has been recognized to be effective into preventing and alleviating lifestyle-related diseases, such as obesity and type 2 diabetes. The rare sugar ᴅ-allulose is a functional monosaccharide with anti-obesity effects. In the present study, we examined the effects of dietary ᴅ-allulose on body fat accumulation in rats fed severely carbohydrate-restricted diets containing high concentrations of different fats, beef tallow, or soybean oil. Methods: Male Wistar rats (n = 35, 3-week-old) were divided into 5 groups: One chow-fed control (C) group, and four carbohydrate-restricted groups, namely, beef tallow (B), beef tallow + ᴅ-allulose (BA), soybean oil (S), and soybean oil + ᴅ-allulose (SA), with free access to the diet and water for 8 weeks. The B and BA diets contained 23% beef tallow and 2% soybean oil, whereas the S and SA diets contained 25% soybean oil. Furthermore, the BA and SA diets contained 5% ᴅ-allulose. Results: The final body weight, weight gain, and food intake were significantly higher, and food efficiency was significantly lower in the control group compared to the other carbohydrate-restricted groups. Intra-abdominal adipose tissue, carcass fat, and total body fat weights were not influenced by dietary fat type or ᴅ-allulose supplementation, except for the epididymal adipose tissue weight. In contrast, carbohydrate restriction suppressed body weight gain in rats, but remarkably increased body fat accumulation. Conclusion: Under carbohydrate-restricted conditions, no anti-obesity effects of dietary ᴅ-allulose were observed, regardless of the dietary fat type. The causes of these effects are unknown. However, they may be influenced by a very low carbohydrate and high protein diet. Further research is required to elucidate the effects of ᴅ-allulose under various nutrient compositions with different fat, carbohydrate, and protein energy ratios.

발목관절 가동술과 결합한 전신진동운동이 뇌졸중 환자의 보행 기능과 균형 능력에 미치는 영향: 무작위 대조 예비연구 (Effects of the Whole-body Vibration Exercise Combined with Ankle Joint Mobilization on the Gait Function and Balancing Ability in Stroke Patients: A Preliminary Randomized, Controlled Study)

  • 손수봉;최경욱;김태우;박상영;차용준
    • 대한물리의학회지
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    • 제17권4호
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    • pp.103-111
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    • 2022
  • PURPOSE: This study was performed to investigate the effects of the whole-body vibration exercise combined with ankle joint mobilization on the gait and balancing ability in patients with hemiplegic stroke. METHODS: A total of 19 patients at a rehabilitation hospital who had suffered a hemiplegic stroke were randomly assigned to the experimental group (whole-body vibration exercise combined with ankle joint mobilization, n=10) or control group (whole-body vibration exercise, n=9). All participants underwent 30 min of comprehensive rehabilitation therapy (5 × /week for 6 weeks). Additionally, the experimental group performed the whole body vibration exercise and ankle joint mobilization (15 minutes each, 30 minutes total, 3 × / week for 6 weeks). In the control group, only the whole- body vibration exercise was performed in the same manner and not the ankle joint mobilization. The gait and balancing abilities were measured before and after the 6-week training. RESULTS: Significant improvements were observed in the 10-m walk test, timed up-and-go (TUG) test, center of pressure (COP) path length, and COP path velocity in the experimental group (p < .05). The experimental group showed a larger decrease in the COP path length and velocity than the control group (COP path length, -10.27 mm vs. -3.67 mm, p < .05; COP path velocity, -.33 cm/sec vs. -.13 cm/sec, p < .05, respectively). CONCLUSION: The whole-body vibration exercise combined with ankle joint mobilization could be effective in improving the gait and balancing ability of stroke patients and could also be more effective for improving the static balance ability than the general whole-body vibration exercise alone.

NUMERICAL METHOD IN WAVE-BODY INTERACTIONS

  • MOUSAVIZADEGAN S. H.;RAHMAN M.
    • Journal of applied mathematics & informatics
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    • 제17권1_2_3호
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    • pp.73-91
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    • 2005
  • The application of Green's function in calculation of flow characteristics around submerged and floating bodies due to a regular wave is presented. It is assumed that the fluid is homogeneous, inviscid and incompressible, the flow is irrotational and all body motions are small. Two methods based on the boundary integral equation method (BIEM) are applied to solve associated problems. The first is a low order panel method with triangular flat patches and uniform distribution of velocity potential on each panel. The second method is a high order panel method in which the kernels of the integral equations are modified to make it nonsingular and amenable to solution by the Gaussian quadrature formula. The calculations are performed on a submerged sphere and some floating spheroids of different aspect ratios. The excellent level of agreement with the analytical solutions shows that the second method is more accurate and reliable.

Chlorella Protein의 영양가(營養價)에 관한 연구(硏究) (II) (Nutrition Value of Chlorella (II))

  • 박충웅;황호관
    • 한국식품영양과학회지
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    • 제3권1호
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    • pp.43-46
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    • 1974
  • It was reported that the digestion ratio of chlorella was low because it had a low metabolic rate in body. Generally, the thickness of a cell membrane of it is $200-250\;{\AA}$, the weight of it is approximatly 13% of the total weight of a dry cell. And it is composed of protein, lipid, hemicellulose and ash etc. So, in order to elevate the digestion ratio of chlorella in body, we experimented the crude treatment methods of chlorella. The results obtained in this experiment are summarized as follows : 1. The digestion ratios calculated from ordinary N- balance method were 83.05% for 10% chl. (b) plus diastase group ; 81.25% for 10% chl. (b) plus amylase group, and 79.23% for 10% chl. (b), 58.55% for 10% chl. (a). 2. Biological values from this method were 80.25% for 10% chl. (b) plus diastase group, and 60% for 10% for chlorella(a).

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