• 대한간호학회지
• /
• 제41권4호
• /
• pp.520-527
• /
• 2011

Purpose: The purpose of this study was to examine effects of nitric oxide synthase (NOS) inhibitor on muscle weight and myofibrillar protein content of affected and unaffected hindlimb muscles in rats with neuropathic pain induced by unilateral peripheral nerve injury. Methods: Neuropathic pain was induced by ligation and cutting of the left L5 spinal nerve. Adult male Sprague-Dawley rats were randomly assigned to one of two groups: The NOSI group (n=19) had NOS inhibitor (L-NAME) injections daily for 14 days, and the Vehicle group (n=20) had vehicle injections daily for 14 days. Withdrawal threshold, body weight, food intake and activity were measured every day. At 15 days all rats were anesthetized and soleus, plantaris and gastrocnemius muscles were dissected from hindlimbs. Muscle weight and myofibrillar protein content of the dissected muscles were determined. Results: The NOSI group showed significant increases as compared to the Vehicle group for body weight at 15 days, muscle weight and myofibrillar protein content of the unaffected soleus and gastrocnemius. The NOSI group demonstrated a higher pain threshold than the vehicle group. Conclusion: NOSI for 14 days attenuates unaffected soleus and gastrocnemius muscle atrophy in neuropathic pain model.

• 대한치과보철학회지
• /
• 제35권1호
• /
• pp.181-210
• /
• 1997

The stress distribution generated in the surrounding bone was calculated and compared for various geometry of the dental implants by means of the finite element methods. The models were designed to represent the screw type endosseous implants(varing the size, shape, direction of the screw thread and the angle of the body) with supporting bone and the cylinder type endosseous implants(varing the lower portion-Round type, tapered type) with supporting bone. Static mean bite forces were applied 100N vertically and 25N horizontally on the center of the implant and three dimensional finite analysis was undertaken using software ANSYS 5.1 Version. The result demonstrated that different implant shape leads to significant variations in stress distribution in the bone. In the case of variation of the screw size, direction and shape the implant model with normally directional and triangular screw implied lower stress than with upper directional or lower directional and quadrangular screw but among models a different screw size, within a variation of 0.2mm there was no meaningful difference in maximum stress. In the case of variation of angle of body the straight implied lower stress than the tapered. As a result of analysis of cylinder type, the implants with larger radius of curvature of the round form and larger diameter of the tapered form implied lower stress.

• 천문학회보
• /
• 제39권2호
• /
• pp.89-89
• /
• 2014

While the current consensus view holds that galaxy mergers are commonplace, it is sometimes speculated that Globular Clusters (GCs) may also have undergone merging events, possibly resulting in massive objects with a strong metallicity spread such as Omega Centauri. Galaxies are mostly far, unresolved systems whose mergers are most likely wet, resulting in observational as well as modeling difficulties, but GCs are resolved into stars that can be used as discrete dynamical tracers, and their mergers might have been dry, therefore easily simulated with an N-body code. It is however difficult to determine the observational parameters best suited to reveal a history of merging based on the positions and kinematics of GC stars, if evidence of merging is at all observable. To overcome this difficulty, we investigate the applicability of supervised and unsupervised machine learning to the automatic reconstruction of the dynamical history of a stellar system. In particular we test whether statistical clustering methods can classify simulated systems into monolithic versus merger products. We run direct N-body simulations of two identical King-model clusters undergoing a head-on collision resulting in a merged system, and other simulations of isolated King models with the same total number of particles as the merged system. After several relaxation times elapse, we extract a sample of snapshots of the sky-projected positions of particles from each simulation at different dynamical times, and we run a variety of clustering and classification algorithms to classify the snapshots into two subsets in a relevant feature space.

• PNF and Movement
• /
• 제15권2호
• /
• pp.201-208
• /
• 2017

Purpose: The purpose of this study is to determine the effects of visual biofeedback training on the recovery of balance function in stroke patients. Methods: A total of 30 patients with stroke were chosen as the subjects of this study. The subjects were randomly divided into either the visual biofeedback balance training group (experimental group; n=15) or the general balance training group (control group; n=15). The visual biofeedback balance training and general balance training were implemented for 30 minutes a day, three times a week, for a total of four weeks. The subjects' balance ability was measured before and after the interventions. Results: The shift length and surface area of the center of the body decreased in both the experimental group and the control group, with the difference being statistically significant. The shift length and surface area of the center of the body both decreased more in the experimental group than in the control group, and there was a statistically significant between-group difference. Conclusion: The experimental group showed a greater improvement in terms of the balance ability of patients with stroke than the control group. Therefore, we believe that visual biofeedback balance training can be effectively applied for the improvement of balance ability in patients with stroke.

• Korean Journal of Acupuncture
• /
• 제22권3호
• /
• pp.53-61
• /
• 2005

Objectives : This study was designed to investigate the effect of thermal change on face, acupuncturing Yon-gok (KI2). The room temperature adjust $26^{\circ}C$ making use of air-conditioner. Methods : A Clinical study was done on 20 males and females who didn't have any disease. We used IR-5000 to observe the effects of acupuncture at face temperature. Results : Acupuncturing Yon-gok(KI2), the special region on face falls the temperature (n=20) from Avg.=$28.1400{\pm}0.2603^{\circ}C$ to Avg.=$27.4910{\pm}0.2539^{\circ}C$ the special region on chest falls the temperature (n=20) from Avg.=$26.9450{\pm}0.2591^{\circ}C$ to Avg.=$26.8690{\pm}0.2519^{\circ}C$ These effects result at the stimulating 'Hwa' point, one of five-shu-point one in the meridian, Yon-gok (KI2) is one of 'Hwa'. the stimulating 'Hwa' is able to cure fever, headache, and pains. and it has ablility of controlling body temperature, specially, upper region of whole human body. Conclusions : In conclusion. Acupuncturing Yon-gok (KI2) falls the temperature of region on face, Compared with the temperature of region on chest.

• 대한한의진단학회지
• /
• 제17권3호
• /
• pp.241-252
• /
• 2013

Objectives The purpose of this study was to investigate the effects of walking exercise on diabetes mellitus indicator and vascular compliance of type 2 diabetes mellitus adults. Methods The subjects were 2 groups; exercise group(n=11, $age=57.36{\pm}8.74$), non-exercise group(n=10, $age=59.20{\pm}5.81$). Walking exercise five or more times a week, and more than 10,000 steps per day with writing the walking diary ordered to the exercise group. For date analysis, mean and standard deviation scores were calculated, and independent t-test was performed. Result After 45 days of walking exercise, weight (p <.01), abdominal obesity rate (p <.05), body fat mass (p <.05) showed significant difference between the groups. but diabetes indicators and vascular compliance tend to decreased in the exercise group, there was no significant difference between the groups. Conclusions Walking exercise is effective in improving body composition.

• Physical Therapy Rehabilitation Science
• /
• 제10권2호
• /
• pp.116-123
• /
• 2021

Objective: The purpose of this study was to investigate the effects of myofascial decompressiontherapy using moving suction on body temperature, pain, neck disability index, and cervical rotation for young adult with nonspecific neck pain. Design: Two-group pretest-posttest design. Methods: The subjects were randomly assigned 22 patients with chronic cervical pain who met the study conditions to the experimental group (n=11) and the control group (n=11). In the experimental group, the myofascial decompressiontherapy (MDT) was performed for 10 minutes using moving suction withnegative 15 mmHg pressure from the insertion to the origin of the upper trapezius muscle, while the control group without negative pressure. In order to investigate the effects of the intervention, an infrared thermometer, a visual analogue scale, neck disability index, and goniometer were used. Results: As a result of comparing the pre- and post- changes in each group according to the intervention, skin temperature, pain, neck disability index, and cervical rotation in both the experimental and control groups were significantly improved (p<0.05). Comparison of pre- and post- changes between the experimental and control groups showed significant differences for pain and cervical rotation (p<0.05), but no significant difference was found in the body temperature and neck disability index. Conclusions: Based on the results, MDT using moving suction was effective in reducing pain and increasing of cervical rotation for young adult with nonspecific neck pain.

• Physical Therapy Rehabilitation Science
• /
• 제12권1호
• /
• pp.72-79
• /
• 2023

Objective: Despite known associations between negative body image and health declines in chronic pain patients, few studies have examined longitudinal associations between psychological stress and perceived hand deformities. This study examined whether psychological distress was associated with hand deformities 4 years later and if rural and urban adults differed in the association. Design: A community-based cohort study. Methods: Community dwelling adults (mean age=51.97, 52.3% women) in a rural (n=2968) and urban area (n=2784) provided demographic data at baseline and, in the 4-year follow-up, responded to questionnaires about psychological distress. Perceived hand deformities were assessed at the 8-year follow-up. Linear regression was conducted to examine the effects of psychological distress on hand deformities and moderation by residential areas. Results: The perceived hand deformities were more likely among those with severe psychological stress, hand osteoarthritis, or any chronic disease condition (p<0.01) but less likely among those with younger age, higher education, or income (p<0.01). The regression results showed that psychological distress predicted more perceived hand deformities 4 years later even after adjusting for demographic and health covariates (p<0.01). The residential areas did not significantly moderate the association between distress and hand deformities. Conclusions: This study suggected that psychological distress may trigger later perception of hand deformities in both urband and rural adults. The findings indicate that stress management interventions that are customizable to regional contexts may be effective at preventing negative body image related health problems of community-dewelling adults.

• Maxillofacial Plastic and Reconstructive Surgery
• /
• 제22권2호
• /
• pp.184-190
• /
• 2000

Objective : To compare two different methods of rigid fixation in postoperative stability after mandibular setback. Material and Methods : 28 patients with Class III malocclusion were treated by bilateral sagittal split ramus osteotomy(BSSRO) and mandibular setback were selected for this study. Group A(n=14) had the bone segments fixed with monocortical miniplate on the lateral side of the mandibular body and Group B(n=14) had three noncompressive bicortical screw inserted at the genial area through a transcutaneous approach. Cephalograms were taken preoperatively, postoperatively within 1 weeks and at a follow-up period (mean 8.9 months after surgery) and the amount of setback and postoperative change were measured. Results : Postoperative relapse between two groups was minimal in setback of the mandible. Statistical analysis showed no significant difference in postoperative relapse. Conclusion : This study suggests that both methods of skeletal fixation investigated give comparable postoperative stability and their use in mandibular setback appears to be a fairly stable clinical procedure .

• Nutrition Research and Practice
• /
• 제8권2호
• /
• pp.177-182
• /
• 2014

BACKGROUND/OBJECTIVES: Irisin, a newly identified hormone, is associated with energy homeostasis. We investigated whether aged garlic extract (AGE) and exercise training intervention could improve body weight, insulin sensitivity, skeletal muscle fibronectin domain containing protein 5 (FNDC-5) levels, and plasma irisin in high-fat diet (HFD). MATERIALS/METHODS: Male Sprague Dawley rats were fed a ND (normal diet, n=5) or HFD (n=28) for 6 weeks. After 6 weeks, all rats were divided into 5 groups for the next 4 weeks: ND, (normal diet, n=5), HFD (high-fat diet, n=7), HFDA (high-fat diet + aged garlic extract, n=7), HFDE (high-fat diet + exercise, n=7), and HFDEA (high-fat diet + exercise + aged garlic extract, n=7). Exercise groups performed treadmill exercises for 15-60 min, 5 days/week, and AGE groups received AGE (2.86 g/kg, orally injected) for 4 weeks. RESULTS: Significant decreases in body weight were observed in the ND, HFDE, and HFDEA groups, as compared with the HFD group. Neither intervention affected the masses of the gastrocnemius muscle or liver. There were no significant differences in glucose levels across the groups. The homeostatic model assessments of insulin resistance were significantly higher in the HFD group, as compared with the ND, HFDA, HFDE, and HFDEA groups. However, skeletal muscle FNDC-5 levels and plasma irisin concentrations were unaffected by AGE or exercise in obese rats. AGE supplementation and exercise training did not affect skeletal muscle FNDC-5 or plasma irisin, which are associated with insulin sensitivity in obese rats. CONCLUSION: Our results suggest that the protection against HFD-induced increases in body fat/weight and insulin resistance that are provided by AGE supplementation and exercise training may not be mediated by the regulation of FNDC-5 or irisin.