• 보건행정학회지
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• 제27권1호
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• pp.47-55
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• 2017

Background: This study purposed to analyze the effects of metabolic syndrome on the total medical charge of patients. Methods: 2013 National Health Insurance Service sample research database (eligibility database, medical database, and health examination database) was used for this study. Gamma regression was applied to analyze the effects of metabolic syndrome on the total medical charge and logistic regression was used to determine the probability of medical charge which was higher than the third quartile. Sociodemographic characteristics (age and household income), health behavior factors (smoking, drinking, exercise, and body mass index), and disease related factors (family history and metabolic syndrome) were included as the independent variables. Results: people who had metabolic syndrome spent more medical expenses than those without metabolic syndrome both in man and woman group. The standard regression coefficient was 0.09 (p< 0.001) in man with metabolic syndrome and 0.16 (p< 0.001) in woman. In addition, woman with metabolic syndrome spent more than the third quartile of medical charge. The odds ratios was 1.04 (p= 0.16) for man with metabolic syndrome and 1.18 (p= 0.013) for woman. Conclusion: people with metabolic syndrome spent more medical charge, so it will need to consider policy interventions for preventing the incidence and management of metabolic syndrome in Korean people.

• 한국산학기술학회논문지
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• 제13권3호
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• pp.1186-1193
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• 2012

본 연구는 대사증후군의 위험요인을 파악하여 이를 관리함으로써 심혈관질환 발생을 감소시키는데 필요한 기초자료를 제공하고자 2004년부터 2008년까지 2년 간격으로 검진을 받은 동일인 1,668명을 추적 관찰하여 대사증후군의 발생 및 이의 관련 요인을 조사하기 위한 후향적 코호트연구를 실시하였다. 연구 결과 연도변화에 따른 대사증후군 발생률의 변화는 2004년을 기준으로 2006년 8.3%, 2008년 12.0%로 증가하였다. 동일기간 중 대사증후군 발생의 위험요인을 파악하고자 다중로지스틱회귀분석을 실시하여 위험요인의 상대위험도와 95%신뢰구간을 산출하였다. 그 결과 발생위험 요인으로 연령, 흡연, 총콜레스테롤, ALT, 요산 등이 유의한 변수로 선정되었다.

• 대한영양사협회학술지
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• 제25권2호
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• pp.142-155
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• 2019

The aim of this study was to construct and test a structural equation model for the risk factors of metabolic syndrome in Korean adults. The structural equation model hypothesizes that eating alone and feeling depressed is a risk factor for metabolic syndrome. The data of this study were obtained from the Sixth Korea National Health and Nutrition Examination Survey which was cross-sectional data from the representative national survey. A total of 4,013 subjects replied to the survey item of lifestyle and completed the physical examinations among adults aged 19 years or older in South Korea was in 2015. The structural model in this study was composed of four latent variables: eating alone, depression, negative health behavior, and metabolic syndrome. Two variables, the rate of eating alone and depression, were exogenous variables. Negative health behavior was both a mediating variable and endogenous variable, and metabolic syndrome was the final endogenous variable. The data were analyzed using the Maximum Likelihood method and bootstrapping. The structural model was appropriate for the data based on the model fit indices. The results of this study can be summarized as follows: Eating alone is a direct risk factor of metabolic syndrome in Korean women. Depression can mediate metabolic syndrome through negative health behaviors. Negative health behavior had a direct impact on metabolic syndrome in both men and women. This study may be a guideline for interventions and strategies to reduce the incidence of metabolic syndrome in Korean adults.

• 근관절건강학회지
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• 제29권1호
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• pp.1-10
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• 2022

Purpose: Metabolic syndrome is known as a factor that increases the incidence of chronic diseases, such as diabetes and cardiovascular disease. In particular, the metabolic syndrome among a middle-aged population is rapidly increasing from 15.6% to 31.9%. The purpose of this study was to investigate the effect of muscle strength exercise on the metabolic syndrome in middle aged. Methods: This study was a secondary data analysis using National Health and Nutrition Survey 8th, including 2,739 middle aged people (40~64 years old). We used multivariate logistic regression to identify risk factors associated with metabolic syndrome. Statistical analysis was performed using the SPSS 23.0 program. Results: There were 772 patients in the group with metabolic syndrome and 1,967 patients in the non-metabolic syndrome group. The risk of metabolic syndrome was 1.29 times higher in those who did not do muscle strength exercise than those who did exercise (OR=1.29, 95% CI=1.01~1.66). Conclusion: We have found that muscle strength exercise was effective in lowering the risk of developing metabolic syndrome in middle aged. Thus, it is necessary to develop practical muscle strength exercise and education programs.

• 한국건강관리협회지
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• 제4권1호
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• pp.85-94
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• 2006

Background Cardiovascular disease is becoming an important national health issue since its recent increase in incidence and mortality. The study was conducted to find out the prevalence of metabolic syndrome according to the clinical identification criteria by NCEP-ATP3 and Asia-Pacific criteria. Meterials & Methods: The subjects were 759 people -male 375 and female 384 after twenties age - who had undergone medical examinations at Korea Association of Health, Daejeon- Chungnam Branch. The prevalence of metabolic syndrome was assessed as defined by the NCEP ATP3, while abdominal obesity was assessed according to the Asia-Pacific guidelines. Anthropometric variables and cardiovascular risk factors were measured, and Associated factors with metabolic syndroms was analyzed by logistic regression analysis. Results The prevalence of metabotic syndrome was 24.O% for male and 27.1% for female The high blood pressure was the highest prevalent risk factors of metabolic syndrome. In the age group of thirties, the prevalence of metabolic syndrome was higher in men than in women, however it was significantly higher in women than in men in fifties and six ties. The metabolic syndrome was more prevalent in aged people over 50 years. and .significantly associated with BMI index(odds ratio 2.58 in male, 9.87 in female)Conclusions The prevalence of metabolic syndrome is over 20%.Early detection and intervention of risk factors by health examination and promotion are needed for prevention of metabolic syndrome.

• Gut and Liver
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• 제12권6호
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• pp.655-663
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• 2018

Background/Aims: The association between metabolic syndrome and colorectal cancer (CRC) has been suggested as one of causes for the increasing incidence of CRC, particularly in younger age groups. The present study examined whether the current age threshold (50 years) for CRC screening in Korea requires modification when considering increased metabolic syndrome. Methods: We analyzed data from the National Health Insurance Corporation database, which covers ~97% of the population in Korea. CRC risk was evaluated with stratification based on age and the presence/absence of relevant metabolic syndrome components (diabetes, dyslipidemia, and hypertension). Results: A total of 51,612,316 subjects enrolled during 2014 to 2015 were analyzed. Among them, 19.3% had diabetes, hypertension, dyslipidemia, or some combination thereof. This population had a higher incidence of CRC than did those without these conditions, and this was more prominent in subjects <40 years of age. The optimal cutoff age for detecting CRC, based on the highest Youden index, was 45 years among individuals without diabetes, dyslipidemia, and hypertension. Individuals with at least one of these components of metabolic syndrome had the highest Youden index at 62 years old, but the value was only 0.2. Resetting the cutoff age from 50 years to 45 years achieved a 6% increase in sensitivity for CRC detection among the total population. Conclusions: Starting CRC screening earlier, namely, at 45 rather than at 50 years of age, may improve secondary prevention of CRC in Korea.

• 융합정보논문지
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• 제10권11호
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• pp.240-250
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• 2020

본 연구는 한국 성인의 성별에 따른 혈청 요산 수치와 인슐린저항성 및 대사증후군 구성요소간의 관련성을 확인하고자 하였다. 2018년 6월에서 2020년 5월 사이에 경기지역 종합병원에서 건강검진을 받았던 20세 이상 남성 2,365명, 여성 2,063명 총 4,428명을 대상으로 단면연구를 시행하였다. 연구결과 남녀 모두 정상군보다 대사증후군 진단군에서 요산치가 높았으며, 고요산혈증군에서 대사증후군과 그 구성요소의 발병률은 정상군보다 높았다. 고요산혈증은 남성에서 혈압상승(p=0.006)과 고중성지방혈증(p<0.001), 여성에서 대사증후군(p=0.012)과 낮은 HDL-콜레스테롤(p<0.001) 발병 위험을 높이는 요인으로 나타났다. 따라서 남성과 여성 모두에서 고요산혈증은 대사증후군 및 그 구성요소와 관련이 있었으며, 특히 여성에서 대사증후군 발병의 독립적인 예측인자임을 확인하였다.

• Journal of Nutrition and Health
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• 제52권6호
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• pp.569-580
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• 2019

본 연구에서는 한국인유전체역학조사사업에서 수집한 2001 ~ 2002년 기반조사 자료로부터 건강한 한국 성인 3,560명의 배추김치 섭취빈도에 따른 일반적 특성, 식품군 섭취빈도와 영양소 섭취량을 분석하였고, 이들 중 2,259명을 대상으로 10년 추적조사에서 대사증후군과 그 구성 요소의 발생률 위험도를 분석하였다. 기반조사에서의 배추 김치 섭취빈도에 따라 1일 기준으로 '1회 미만 섭취군', '1 ~ 2회 섭취군', '3회 섭취군'으로 대상자를 분류하였으며, 세 집단 간 성별에 따른 유의적인 차이는 없었고, 남녀 모두 연령, 교육수준, 소득수준, 거주지역에서 유의적인 차이가 있었다. 배추김치 섭취빈도에 따라 식품군 섭취빈도는 연령, 교육수준, 소득수준, 거주지역, 음주여부와 에너지 섭취량으로 보정한 후 남녀 모두에서 3회 섭취군의 밥류와 두류의 섭취빈도가 다른 두 군의 섭취빈도보다 높았으며, 육류의 섭취빈도는 낮았다. 배추김치 섭취빈도가 높을수록 남녀 모두 에너지 섭취량이 많았으며, 대부분의 영양소 섭취량도 많았다. 10년의 추적기간 동안 대상자 2,259명 중 933명이 대사증후군을 나타냈으며, 배추김치 섭취빈도에 따라 남자의 경우에는 대사증후군 발생률 위험도에 유의적 차이가 없었으나, 여자의 경우 교란변수인 연령, 교육수준, 소득수준, 거주지역, 음주여부, 에너지 섭취량으로 보정한 후에도 HR이 0.63 (95% CI: 0.47 ~ 0.86)으로 유의적으로 감소한 것으로 나타났다. 결론적으로 지역사회기반 코호트의 10년 추적조사 결과 성인 여자의 경우 배추김치를 1일 3회 섭취하는 집단은 1회 미만 섭취하는 집단에 비해 대사증후군 발병 위험이 낮은 것으로 나타났다.

• Journal of Preventive Medicine and Public Health
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• 제55권5호
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• pp.475-484
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• 2022

Objectives: This study aimed to determine the association between metabolic syndrome (MetS) and the incidence of colorectal cancer (CRC) in Korean women with obesity. Methods: Cancer-free women (n=6 142 486) aged 40-79 years, who underwent National Health Insurance Service health examinations in 2009 and 2010 were included. The incidence of CRC was followed until 2018. The hazard ratio (HR) of MetS for the incidence of colon and rectal cancer was analyzed according to body mass index (BMI) categories, adjusting for confounders such as women's reproductive factors. In addition, the heterogeneity of associations across BMI categories was assessed. Results: Women with MetS were at increased risk of colon and rectal cancer compared to women without MetS (HR, 1.20; 95% confidence interval [CI], 1.16 to 1.23 and HR,1.15; 95% CI, 1.11 to 1.20), respectively. The HR of MetS for colon cancer across BMI categories was 1.12 (95% CI, 1.06 to 1.19), 1.14 (95% CI, 1.08 to 1.20), and 1.16 (95% CI, 1.12 to 1.21) in women with BMIs <23.0 kg/m², 23.0-24.9 kg/m², and ≥25.0 kg/m², respectively. The HR of MetS for rectal cancer across corresponding BMI categories was 1.16 (95% CI, 1.06 to 1.26), 1.14 (95% CI, 1.05 to 1.23), and 1.13 (95% CI, 1.06 to 1.20). The heterogeneity of associations across BMI categories was not significant in either colon or rectal cancer (p=0.587 for colon cancer and p=0.927 for rectal cancer). Conclusions: Women with MetS were at increased risk of colon and rectal cancer. Clinical and public health strategies should be considered for primary CRC prevention with an emphasis on improving women's metabolic health across all BMI groups.

• Journal of Nutrition and Health
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• 제41권4호
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• pp.327-340
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• 2008

This study was designed to investigate the correlation between nutrition status and cardiovascular disease in type 2 diabetes patients with metabolic syndrome. The subjects were 66 patients and divided into Non MS (a group without metabolic syndrome, n = 37) and MS (a group with metabolic syndrome, n = 29). The percentage of patients accompanying metabolic syndrome was 43.9% and family history such as DM, skipping meal and eating speed were higher in MS (P < 0.05) The average values of BMI, body fat (%), waist circumference were significantly higher in patients of MS than that of Non MS. For hamatological values, MS showed higher FRS, HOMA-IR, LDL-Cholesterol, CRP. Percentage of FRS was 21.63% in MS that is relatively higher in comparison with 16.81% in Non MS. Moreover, the incidence of cardiovascular disease appeared 13.8% in MS that is higher than 2.7% in Non MS. The intake of sodium and vitamin E were higher, but the intake of fat, vitamin A and zinc were lower in MS than in Non MS. Close correlations were elucidated among FRS, occurrence of cardiovascular disease, weight, waist circumference, Total-Cholesterol, LDLCholesterol, sodium in both groups. In conclusion, cardiovascular disease risk factors would be higher in type 2 diabetes patients with metabolic syndrome and there were distinctive patterns that were associated with hamatological values, nutrition intake risk factors. This result should be considered when designing nutrition study and intervetion programs.