• 디지털융복합연구
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• 제13권5호
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• pp.329-336
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• 2015

본 연구는 저항성 운동과 유산소 운동의 복합 운동 프로그램으로 구성된 체력관리 수업과 일반 교양체육 수업 간에 비만도와 대사증후군 위험인자의 개선 및 체력 향상 정도에 차이가 있는지를 밝혀내어 융복합적인 웰니스를 위한 체력관리 수업의 필요성을 제시하고자 하였다. 피험자는 본교 체력관리 수강 남학생 113명, 본교 교양체육 실기과목 수강 남학생 67명, 타 대학의 운동과 다이어트 및 건강관리 수업 수강 남학생 40명 총 220명을 연구 대상으로 설정하였다. 비만지표, 대사증후군 위험인자 및 건강 기술관련 체력 변인들은 세 집단 간 수업 전후의 상호작용을 검정하기 위해 이원변량분석(Repeated two-way ANOVA)을 실시하였다. 연구결과, 체력관리 수업이 본교 교양체육 수업과 타 대학 교양체육 수업보다 개인의 비만도와 대사증후군 위험인자를 개선시키고 체력을 향상시키는 것으로 나타났다. 결론적으로 체력관리 교양수업은 기존의 스포츠 실기 및 이론 교양수업에 비해 학생들의 건강과 체력을 효율적으로 증진시킬 수 있는 교과목인 것으로 사료된다.

• 대한지역사회영양학회지
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• 제27권3호
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• pp.223-244
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• 2022

Objectives: This study was designed to investigate the relationship between metabolic risk factors, Index of Nutrition Quality, and the dietary quality index score of Korean adults. Methods: The subjects were 18,652 Korean adults aged 19 years or older (7,899 males, 10,753 females) who participated in the 2016-2019 Korea National Health and Nutrition Examination Survey. Subjects were divided into normal, pre-metabolic syndrome, and metabolic syndrome (MetS) groups according to the number of their metabolic risk factors. Data were analyzed using the SPSS program. Results: About 44.7% of men in the MetS group were at least college graduates (P < 0.001), whereas 52.0% of women in the MetS group were middle school graduates or lower (P < 0.001). The frequency of fruit and dairy products intake tended to decrease as the number of metabolic risk factors increased in both men and women (P for trend < 0.001). As the number of metabolic risk factors decreased, the frequency of grain intake tended to decrease in men (P for trend < 0.001) while the frequency of intake of red meat (P for trend = 0.001), poultry (P for trend < 0.001), and eggs (P for trend < 0.001) decreased in women. The total scores of Diet Quality Index-International (DQI-I) (men P < 0.001, women P < 0.01) and Korean Healthy Eating Index (KHEI) (men and women P < 0.001) were significantly lower in the MetS group compared to the other groups, and the total score of DQI-I and KHEI tended to decrease as the number of metabolic risk factors increased. Conclusions: Dietary quality evaluation using various indices can provide more information on the dietary problems related to metabolic risk factors. Nutrients and foods that have been confirmed to be related to metabolic risk factors can be used to develop dietary guidelines for the nutritional management of metabolic diseases.

• 대한지역사회영양학회지
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• 제20권6호
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• pp.460-467
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• 2015

Objectives: Excess sodium intake has been linked to obesity and obesity-related indices. However, the scientific evidence for this association is inadequate. The purpose of this study was to investigate the association between urinary sodium excretion and obesity-related indices among Korean adults. Methods: A convenience sample of 120 subjects (60 obese and 60 non-obese subjects) were recruited applying frequency matching for sex and age between two groups. Sodium intake level was assessed through 24-hour urine collection. Obesity-related metabolic risk factors, including fasting blood lipid indices, subcutaneous and visceral fat through computed tomography (CT), insulin resistance indices, blood pressure and liver enzymes were measured in all subjects. These obesity-related metabolic risk factors were compared between obese and non-obese group according to sodium excretion levels (<110 mEq/day, 110~180 mEq/day, >180 mEq/day). Results: After adjusting for age, gender, health behaviors (smoking, exercise, drinking), and energy intake, several obesity-related metabolic risk factors, including abdominal circumference, body fat percentage, subcutaneous and visceral fat, triglyceride, and systolic blood pressure were found to be significantly deteriorated as the sodium excretion level increases. In addition, multivariate adjusted-odds ratios of abdominal obesity, high blood triglyceride, and high blood pressure were found significantly higher in the highest sodium excretion group compared to the lowest group. The mean number of metabolic syndrome risk factors was also significantly greater in the highest sodium excretion group than in the lowest group. Conclusions: The current study findings suggested that high sodium intake can affect obesity and metabolic syndrome risk negatively, implying the necessity of future research on low-sodium diet intervention in relation to obesity and related health problems.

• Journal of Nutrition and Health
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• 제46권6호
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• pp.531-539
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• 2013

The prevalence of metabolic syndrome (MetS) in Korea has been increasing in adults, as well as in adolescents. Recently the prevalence of MetS in children has been reported to strongly link that of MetS in parents. Families are known to share similar food environment so that eating habits of parents closely resemble that of the children's. Therefore, the aim of this study to examine metabolic risk factors and dietary intake in children by with respect to mother's metabolic syndrome, based on the data from Korean National Health and Nutrition Examination Survey (KNHANES) 2007-2010. Using the household variable and the eldest child per household, 1,341 pairs of mothers and children were selected. The mothers were defined by MetS criteria, and then the children were classified into the following three groups in accordance to the mothers' MetS; children whose mothers had none, 1-2, and 3 or more components of MetS. All dietary data were evaluated using the data from a food frequency questionnaire. The mean age was $42.6{\pm}4.2$ years for the mothers, and $14.9{\pm}2.0$ years for the children. Children whose mothers had 3 or more components of MetS showed a significantly higher prevalence of overweight and higher level of fasting triglyceride; conversely, they showed a lower level of serum HDL-cholesterol compared to the other two groups. Regarding an agreement of food consumption between the mothers and children, most food groups showed high agreement, except in the category of beverages. Regarding the dietary habits and family meals, children whose mothers had 3 or more components of MetS were more likely to skip breakfast and less likely to have family meals at breakfast or snack. In conclusion, the children's metabolic risk factors and dietary factors were different with respect to the status of mothers' MetS. Further studies are necessary to examine the causal effect of family environment in children's health status.

• 한국식품영양학회지
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• 제33권3호
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• pp.322-330
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• 2020

The purpose of this study was to investigate the comparison of nutrient intake and metabolic syndrome between single person households and non-single person households in elderly subjects. We analyzed data from 2,903 subjects ≥ age 65 who participated in the Korea National Health and Nutrition Examination Survey (KNHANES) 2013~2015. As a result, single-person households had lower income and economic ability, overall nutrient intake was deteriorated, and the proportion of high-carbohydrate intake was high, compared to non-single person households. After adjusting for potential confounders (sex, age, education, household income, economic activity, smoking status, alcohol consumption, walking frequency, health status, depression status, and dietary factors), the single-person household showed a tendency of 1.22-fold higher ORs of metabolic syndrome and 1.3-fold higher ORs of hypertriglyceridemia than the non-single-person household. We suggest that the single-person household may be associated with increased prevalence of metabolic syndrome and hypertriglyceridemia in the elderly subjects.

• 한국산학기술학회논문지
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• 제15권9호
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• pp.5660-5667
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• 2014

본 연구는 국가자료인 2012년도 국민건강영양조사 자료를 이용하여 20세 이상 성인(n=5,889)에서 대사증후군 및 Metabolic syndrom score(MSS)와 맥압(Pulse pressure, PP)의 관련성을 평가하고자 실시하였다. 연구결과에서 맥압에 대한 관련변수를 보정하였을 때, 맥압에 대한 평균값이 MSS 0은 $41.30{\pm}0.34mmHg$, MSS 1은 $42.16{\pm}0.31mmHg$, MSS 2는 $44.73{\pm}0.34mmHg$, MSS 3은 $46.46{\pm}0.42mmHg$, MSS 4는 $48.62{\pm}0.58mmHg$, MSS 5는 $53.50{\pm}1.05mmHg$으로 MSS가 증가할수록 증가하였고(p<0.001), Non-Metabolic syndrome군($42.77{\pm}0.19mmHg$)에 비하여 Metabolic syndrome군($47.25{\pm}0.34mmHg$)에서 유의하게 증가하였다(p<0.001). 또한 관련변수를 보정한 후 Hyper-PP(>61 mmHg)의 Odd Ratio(OR)값은 MSS 0에 비하여 MSS 1은 4.49(95% confidence interval[CI], 2.68-7.57), MSS 2는 8.01(95% CI, 4.77-13.47), MSS 3은 11.37(95% CI, 6.67-19.35), MSS 4는 19.69(95% CI, 11.20-34.60), MSS 5는 34.07(95% CI, 17.44-66.52)로 MSS가 증가할수록 Hyper-PP의 OR값도 증가하였고, Non-Metabolic syndrome군에 비하여 Metabolic syndrome군[2.83(95% CI, 2.29-3.49)]에서 유의하게 증가하였다. 결론적으로 대사증후군과 MSS의 증가는 맥압을 증가시킨다.

• Biomolecules & Therapeutics
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• 제31권6호
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• pp.583-598
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• 2023

Dementia is a clinical syndrome characterized by progressive impairment of cognitive and functional abilities. As currently applied treatments for dementia can only delay the progression of dementia and cannot fundamentally cure it, much attention is being paid to reducing its incidence by preventing the associated risk factors. Cardiovascular and metabolic diseases are well-known risk factors for dementia, and many studies have attempted to prevent dementia by treating these risk factors. Growing evidence suggests that sex-based factors may play an important role in the pathogenesis of dementia. Therefore, a deeper understanding of the differences in the effects of drugs based on sex may help improve their effectiveness. In this study, we reviewed sex differences in the impact of therapeutics targeting risk factors for dementia, such as cardiovascular and metabolic diseases, to prevent the incidence and/or progression of dementia.

• 대한임상검사과학회지
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• 제50권3호
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• pp.245-252
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• 2018

한국 노인을 대상으로 대사증후군 예측인자로서 혈중 Non HDL-콜레스테롤과 중성지방/HDL-콜레스테롤 비율의 임상적용 가능성을 평가하고자 하였다. 2015년 1월부터 2017년 12월까지 경기지역 종합병원의 건강검진센터를 내원하여 건강검진을 실시한 65세 이상 노인을 1,543명을 대상으로 하였다. 대사증후군은 American Heart Association/National Heart, Lung, and Blood Institute (AHA/NHLBI)기준에 따라 진단하였다. 복부비만은 World Health Organization (WHO) West Pacific Region에서 제시하는 아시아-태평양인의 기준을 적용하였다. Non HDL-콜레스테롤은 총콜레스테롤과 HDL-콜레스테롤의 차이로 계산하였다. 대사증후군 예측력은 Non HDL-콜레스테롤보다 중성지방/HDL-콜레스테롤 비율이 높게 나타났다. 관련요인을 보정한 후 중성지방/HDL-콜레스테롤 비율은 1사분위수보다 4사분위수의 대사증후군 발병 위험이 높았다. 또한 대사증후군 발병을 예측하는 중성지방/HDL-콜레스테롤 비율의 적정 기준값은 2.8이었다. 중성지방/HDL-콜레스테롤 비율은 대사증후군 위험을 평가하는 간단하고 실용적인 지표가 될 수 있겠다.

• Journal of Preventive Medicine and Public Health
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• 제42권3호
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• pp.160-164
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• 2009

Objectives : The objective of this study was to determine the relationship between past smoking and the risk factors for metabolic syndrome. Methods : From January 2007 to December 2007, a total of 3,916 over thirty years old male health screen examinees were divided into the nonsmoking, smoking, ex-smoking groups. The diagnosis of metabolic syndrome was based on the criteria of the NCEP ATP III(Executive Summary of The Third Report of The National Cholesterol Education Program). Metabolic syndrome was defined as the presence of three or more of the following: a blood pressure $\geq$ 130/85 mmHg, a fasting glucose level $\geq$ 110 mg/dL, a HDL-C (High Density Lipoprotein Cholesterol) level < 40 mg/dL, a triglyceride level $\geq$ 150 mg/dL and, a waist circumference men $\geq$ 102 cm, but a waist to hip ratio > 0.90 was used as a surrogate for the waist circumference. Results : After adjustment for age, alcohol consumption and, exercise in the smokers, for the ex-smokers compared with the nonsmokers, the odds ratio (OR) of a lower HDL cholesterol level (<40 mg/dL) was 1.29 (95% CI=1.03-1.61) in the smokers, the ORs of a higher triglyceride level were 1.35 (95% CI=1.09-1.66) in the ex-smokers and, 2.12 (95% CI=1.75-2.57) in the smokers, and the OR of a waist to hip ratio was 1.25 (95% CI=1.03-1.52) in the ex-smokers. When there were over three components of metabolic syndrome in the ex-smokers and smokers as compared with the nonsmokers, the odds ratio against the risk of metabolic syndrome were 2.39 (95% CI=1.00-6.63) and 2.37 (95% CI=1.02-6.46), respectively. Conclusions : The present study suggested that there is an association of smoking with metabolic syndrome in men.

• 한국산학기술학회논문지
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• 제17권6호
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• pp.147-156
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• 2016

본 연구는 대사증후군 환자의 건강관리를 위한 기초자료를 제공하고자 대사증후군 환자의 호전과 그 관련된 요인을 파악하였다. 2013년 1월부터 2014년 12월까지 대학병원 종합검진센터에서 2년 연속 검진 받은 만 20세 이상 성인 중 2013년 검진에서 대사증후군 진단을 받은 280명을 대상으로 하였다. 자료 분석은 SPSS WIN18.0을 이용하여 평균과 표준편차, t-검정, ${\chi}^2$ 검정, 로지스틱 회귀분석을 하였다. 연구결과 호전군의 대사증후군 구성요소는 기준년도(2013년)의 3개에서, 추적년도(2014년)에 2개로 감소된 비율이 60.6%로 가장 높았다. 호전군은 기준년도에 비해 추적년도에 허리둘레, 수축기 혈압, 중성지방의 감소 및 고밀도 지단백 콜레스테롤 증가가 유의한 차이를 보였다. 대사증후군 호전군과 유지군 간에는 음주, 운동, 열량, 지방, 당질 섭취 및 지질저하제 복용에서 유의한 차이를 보였다. 로지스틱 회귀분석에서 대사증후군 호전에는 운동, 열량섭취, 당뇨병 복용 유지가 유의한 영향력을 보였다. 본 연구의 결과 대사증후군 관리를 위해서는 운동증가, 식생활개선을 위한 중재프로그램 제공이 필요하며, 이를 지속적으로 관리하기 위한 보건교육 강화가 요구되었다.