• Title/Summary/Keyword: metabolic disease

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A Case of Adult Onset Glycogen Storage Myopathy (성인형 당원축적근육병 1예)

  • Shin, Jung Hwan;Kim, Dong Gun;Shin, Je Young;Park, Sung Hye;Lee, Kwang Woo
    • Annals of Clinical Neurophysiology
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    • v.16 no.2
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    • pp.81-85
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    • 2014

  • Primary metabolic myopathy as a type of congenital myopathies was first described by McArdle in 1951. Glycogen storage disease is a disease caused by genetic mutations involved in glycogen synthesis, glycogenolysis or glycolysis. Several types of glycogen storage disease are known to cause metabolic myopathies. We report a case of adult onset metabolic myopathy with glycogen storage.

  • https://doi.org/10.14253/kjcn.2014.16.2.81 인용 PDF KSCI

Independent beneficial effects of aged garlic extract intake with regular exercise on cardiovascular risk in postmenopausal women

  • Seo, Dae-Yun;Lee, Sung-Ryul;Kim, Hyoung-Kyu;Baek, Yeong-Ho;Kwak, Yi-Sub;Ko, Tae-Hee;Kim, Na-Ri;Rhee, Byoung-Doo;Ko, Kyoung-Soo;Park, Byung-Joo;Han, Jin
    • Nutrition Research and Practice
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    • v.6 no.3
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    • pp.226-231
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    • 2012

  • The purpose of the study was to assess the effects of a 12 weeks aged garlic extract (AGE) regimen with regular exercise on cardiovascular disease (CVD) risk in postmenopausal women. A total of 30 postmenopausal women ($54.4{\pm}5.4$ years) were randomly divided into the following four groups: Placebo (Placebo; n = 6), AGE intake (AGEI; n = 8), exercise and placebo (Ex + Placebo; n = 8), exercise and AGE (Ex + AGE; n = 8) groups. The AGE group consume 80 mg per day, and exercise groups performed moderate exercise (aerobic and resistance) three times per week. After 12 weeks of treatment, body composition, lipid profile, and CVD risk factors were analyzed. Body weight was significantly decreased in AGEI, Ex + Placebo, and Ex + AGE groups compared to baseline. Body fat % was significantly decreased in the AGEI and Ex + Placebo groups. Body mass index (BMI) was significantly decreased in the AGEI, Ex + Placebo, and Ex + AGE groups. Fat-free mass was significantly decreased in the AGEI group. Total cholesterol (TC) was significantly lower in the Ex + Placebo compared to the Placebo group. AGE supplementation or exercise effectively reduced low-density lipoprotein (LDL-C). Triglyceride (TG) was significantly increased in the AGEI group. Malondialdehyde (MDA) levels were significantly decreased in the AGEI, Ex + Placebo, and Ex + AGE compared to the placebo group. AGE supplementation reduced homocysteine levels regardless of whether the women also exercised. The present results suggest that AGE supplementation reduces cardiovascular risk factors independently of exercise in postmenopausal women.

  • https://doi.org/10.4162/nrp.2012.6.3.226 인용 PDF KSCI

BH4 결손증 13례

  • Lee, Dong-Hwan;Hong, Yong-Hui;Lee, Yong-Hwa
    • Journal of The Korean Society of Inherited Metabolic disease
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    • v.9 no.1
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    • pp.9-10
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    • 2009

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