• Journal of Information Technology Applications and Management
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• 제30권1호
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• pp.71-80
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• 2023

The purpose of this study is to promote understanding of physical activity and metabolic syndrome in middle-aged adults and to provide basic data of interventions development for the prevention and management of metabolic syndrome. Using the 2020 data for Korea National Health and Nutrition Examination Survey, 1,786 middle-aged adults between the ages of 40 and 64 with no missing data were analyzed. As a result of the study, 56.5(±2.1)% of men and 52.9(±1.81)% of women were sufficient activity group among physical activity, and the proportion of men was higher than that of women, but it was not statistically significant(t=1.27, p=.207). The prevalence of metabolic syndrome was 38.9(±2.1%) of men and 25.4(±1.5)% of women, the prevalence of men was significantly higher than that of women(t=5.12, p<.001). Compared to the insufficient activity group, the sufficient activity group had a 0.71(95% CI: 0.57~0.88) times the risk of developing low HDL(high density lipoprotein)- cholesterol(p=.002), and this pattern was maintained even after adjusting for age, education level, body mass index, smoking status, and drinking status(p=.002). Based on the results of this study, a physical activity and metabolic syndrome risk group in middle-aged adults should be selected, and physical activity promotion program to improve high density lipoprotein-cholesterol among metabolic syndrome indicators should be developed.

• Journal of Preventive Medicine and Public Health
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• 제41권6호
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• pp.427-433
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• 2008

Objectives: This study was performed to assess the association between physical activity and the clustering of metabolic abnormalities among Korean children. The effect of substituting moderate to vigorous physical activity for the time spent in inactivity was examined as well. Methods: The study subjects were comprised of 692 (354 boys, 338 girls) 4th grade elementary school students. We used a modified form of the physical activity questionnaire that was developed in the Five-City Project. The subjects with clustering of metabolic abnormalities were defined as having two or more of the following five characteristics: waist circumference ${\geq}90\;%$, systolic or diastolic blood pressure ${\geq}90\;%$, fasting glucose ${\geq}110\;mg/dl$, triglycerides ${\geq}110\;mg/dl$ and HDL cholesterol ${\geq}40\;mg/dl$. We calculated the odds ratios to assess the effect of substituting moderate to vigorous physical activity for time spent in inactivity. Results: The risk of clustered metabolic abnormalities was inversely correlated with the increased time spent on moderate to vigorous physical activity, but the correlation was not significant. The odds ratio for clustering of metabolic abnormalities that represented the effect of substituting moderate to vigorous physical activity for 30minutes of sedentary activity was 0.87(95% Cl=0.76-1.01). Conclusions: These findings suggest that substituting moderate to vigorous physical activity for sedentary activity could decrease the risk of clustered metabolic abnormalities.

• 한국보건간호학회지
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• 제33권1호
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• pp.20-32
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• 2019

Objectives: This study identified biopsychosocial factors associated with metabolic syndrome among Korean men and women aged over 40 years. Methods: Secondary data from the 2010-2016 Korean National Health and Nutrition Examination Survey were used for this study. Based on the biopsychosocial model, psychosocial factors (stress, depression, smoking, binge alcohol consumption, physical activity) were assessed with control of biomedical (age, body mass index, family history of hypertension, dyslipidemia, type 2 diabetes mellitus, and cardiovascular disease) and biosocial factors (educational level and economic status). Data from 8,624 men and 7,321 women were analyzed by logistic regression analysis using a complex sample procedure. Results: Among men, current or past smoking habits (Adjusted Odds Ratio [AOR]: 1.349; 95% Confidence Interval [CI]: 1.155-1.575, p<.001) and binge alcohol consumption (AOR: 1.570, CI: 1.389-1.774, p<.001) were associated with metabolic syndrome. In addition, moderate (AOR: 1.205, CI: 1.038-1.400, p=.014) and low levels of physical activity (AOR: 1.296, CI: 1.109-1.514, p=.001) were associated with metabolic syndrome. Among women, low level of physical activity (AOR: 1.276, CI: 1.017-1.602, p=.036) was associated with metabolic syndrome. Conclusion: Gender specific interventions such as encouraging physical activity and prevention of smoking and excessive alcohol drinking are important to prevention of metabolic syndrome.

• 대한예방한의학회지
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• 제15권1호
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• pp.89-98
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• 2011

Objectives : The aim of this study was to investigate the prevalence of metabolic syndrome and the association between lifestyle factors and the risk of metabolic syndrome in Korean adolescents. Methods : The metabolic syndrome was defined with ${\geq}$ 3 metabolic abnormalities using the age-modified criteria of the Adult Treatment panel III specified by National Cholesterol Education Program in adolescents aged 12 to 18 years who have participated in the Kroean National Health and Nutrition Examination Survey in 1998(n＝936) and 2008(n＝620). Physical activity and dietary intakes were assessed. Results : The overall prevalence of metabolic syndrome in Korean adolescents declined over 10 years (P < 0.01). Adolescents engaging regular exercise significantly increased over 10 years (P < 0.001). Physically activity was associated with a lower risk of metabolic syndrome (P < 0.001). Dietary intake patterns were not associated with a risk of metabolic syndrome. Conclusions : The prevalence of metabolic syndrome among Korean adolescents declined over 10 years which may be in part due to the increased regular physical activity. The risk of metabolic syndrome is lower in individuals who are physically active.

• Journal of Microbiology and Biotechnology
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• 제33권6호
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• pp.715-723
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• 2023

Microbial biofilms are resilient, immune-evasive, often antibiotic-resistant health challenges, and increasingly the target for research into novel therapeutic strategies. We evaluated the effects of a nutraceutical enzyme and botanical blend (NEBB) on established biofilm. Five microbial strains with known implications in chronic human illnesses were tested: Candida albicans, Staphylococcus aureus, Staphylococcus simulans (coagulase-negative, penicillin-resistant), Borrelia burgdorferi, and Pseudomonas aeruginosa. The strains were allowed to form biofilm in vitro. Biofilm cultures were treated with NEBB containing enzymes targeted at lipids, proteins, and sugars, also containing the mucolytic compound N-acetyl cysteine, along with antimicrobial extracts from cranberry, berberine, rosemary, and peppermint. The post-treatment biofilm mass was evaluated by crystal-violet staining, and metabolic activity was measured using the MTT assay. Average biofilm mass and metabolic activity for NEBB-treated biofilms were compared to the average of untreated control cultures. Treatment of established biofilm with NEBB resulted in biofilm-disruption, involving significant reductions in biofilm mass and metabolic activity for Candida and both Staphylococcus species. For B. burgdorferi, we observed reduced biofilm mass, but the remaining residual biofilm showed a mild increase in metabolic activity, suggesting a shift from metabolically quiescent, treatment-resistant persister forms of B. burgdorferi to a more active form, potentially more recognizable by the host immune system. For P. aeruginosa, low doses of NEBB significantly reduced biofilm mass and metabolic activity while higher doses of NEBB increased biofilm mass and metabolic activity. The results suggest that targeted nutraceutical support may help disrupt biofilm communities, offering new facets for integrative combinational treatment strategies.

• 근관절건강학회지
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• 제23권1호
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• pp.1-8
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• 2016

Purpose: This study was to examine the effects of 12-week Tai Chi exercise on the autonomic nervous system activity and risk factors of metabolic syndrome in patients with metabolic syndrome. Methods: A single group pre-posttest was used. Subjects were 16 participants aged 51~71 years with metabolic syndrome. All of the subjects were met the criteria of the National Cholesterol Education Program-Adult Treatment Panel III (NCEP-ATP III). The Tai Chi exercise consisted of 19 movements from Yang and Sun styles provided twice a week for 3 months. Metabolic syndrome risk factors including waist circumference, blood pressure, glucose, triglyceride, high density lipoprotein cholesterol (HDL-cholesterol) were measured. A heart rate variability device was used to measure the activity of autonomic nervous system. Results: After 12-week Tai Chi exercise, systolic pressure, waist circumference, and HDL-cholesterol improved significantly. Tai Chi exercise had no effect on the autonomic nervous system activity. Conclusion: The 12-week Tai Chi exercise was partially effective in managing risk factors of metabolic syndrome. A larger study with longer period to improve the autonomic nervous system activity in patients with metabolic syndrome is needed.

• 한국산학기술학회논문지
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• 제20권6호
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• pp.158-168
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• 2019

본 연구는 국민건강영양조사 제7기 1차년도(2016년) 자료를 이용하여 청소년의 대사증후군과 식생활, 신체활동 및 정신건강과의 관계를 파악 및 분석하여 청소년의 대사증후군 예방과 정신건강 증진을 위한 기초적 자료를 제공하는데 그 목적이 있다. 연구대상자의 연령은 만13세-만18세 청소년으로, 그 중 정상군은 남자 201명(52.6%), 여자 187명(47.4%)으로 나타났으며, 대사증후군은 남자 9명(56.4%), 여자 6명(43.6%)으로 총 403명으로 나타났다. 이에 청소년의 대사증후군과 식생활, 신체활동 및 정신건강과의 관계를 분석하여 연구한 결과, 청소년의 대사증후군에 미치는 주요 영향요인은 다음과 같다. 첫째, 신체특성에서 BMI가 1 증가할 때 마다 대사증후군 유병확률이 1.746배 증가하는 것으로 나타났다. 둘째, 식생활습관에서는 아침식사 빈도에서 주1-2회 식사 시 거의 안할 때 보다 대사증후군 유병확률이 0.87배 감소하는 것으로 나타났다. 셋째, 신체활동에서는 평소 하루 앉아있는 시간이 1시간 증가할 때 마다 대사증후군 유병확률이 1.054배 증가하는 것으로 나타났다. 넷째, 청소년의 대사증후군은 정신건강과의 관련성에 미치는 영향이 없는 것으로 나타났다. 따라서 향후 청소년을 중심으로 한 대사증후군 관련 연구에 있어서 식생활, 신체활동 및 정신건강 등에 관한 다양한 변수들의 개발을 통해 보다 확장된 연구가 필요할 것으로 판단되며 또한 청소년의 대사증후군 예방을 위한 식생활요인과 신체활동요인 및 정신건강요인을 접목한 효과적인 건강교육 중재 프로그램개발이 필요하다.

• 대한간호학회지
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• 제45권4호
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• pp.483-494
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• 2015

Purpose: This study identified effects of dietary and physical activity interventions including dietary interventions or physical activity interventions alone or combined dietary-physical activity interventions to improve symptoms in metabolic syndrome including abdominal obesity, high triglycerides, low high density lipoprotein cholesterol, elevated blood pressure, and elevated fasting glucose through meta-analysis. Methods: Articles on metabolic syndrome X published from 1988 to 2013 were searched through electronic databases, Google Scholar, and reference reviews. Methodological quality was assessed by the checklist, SIGN (Scottish Intercollegiate Guidelines Network). Results: In the meta-analysis, there were 9 articles reporting 13 interventions with 736 participants. Using random effect models, the dietary and/or physical activity interventions showed a lower mean difference in waist circumference ( - 1.30 cm, 95% CI: - 2.44~ - 0.15, p=.027). The combined dietary-physical activity interventions showed a lower mean difference in waist circumference ( - 2.77 cm, 95% CI: - 4.77~ - 0.76, p=.007) and systolic blood pressure ( - 5.44 mmHg, 95% CI: - 10.76~ - 0.12, p=.044). Additionally, interventions of over 24 weeks yielded a lower mean difference in waist circumference ( - 2.78 cm, 95% CI: - 4.69~ - 0.87, p=.004) and diastolic blood pressure ( - 1.93 mmHg, 95% CI: - 3.63~ - 0.22, p=.026). Conclusion: The findings indicate that dietary and/or physical activity interventions for metabolic syndrome reduce central obesity with no adverse effects. This finding provides objective evidences for dietary and physical activity management on metabolic syndrome as an efficient intervention.

• 한국보건간호학회지
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• 제32권2호
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• pp.319-330
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• 2018

Purpose: This study was conducted to determine if physical activity levels relieve the risk of development of metabolic syndrome (Mets) according to smoking intensity among smoking men. Methods: Secondary data from the 2010-2015 Korea National Health and Nutrition Examination Survey were used for this cross sectional study. A total of 3,027 men over the age of 19 were included for data analysis. Complex samples logistic regression was used to analyze the combined effects of smoking and physical activity on Mets. Smoking intensity was categorized as light (${\leq}20cigarettes/day$) or heavy (> 20 cigarettes/day), while physical activity was categorized as light (< 600 metabolic equivalent [MET]-min/week), moderate (600-3,000 MET-min/week), and vigorous (${\geq}3,000MET-min/week$). Results: Mets was less prevalent among light smokers with vigorous physical activity (Adjusted Odds Ratio [AOR]: 0.632, 95% Confidence Interval [CI]: 0.475-0.840) compared to those with light physical activity. Among heavy smokers, physical activity level was not significantly associated with Mets. Conclusion: Only vigorous physical activity exerted protective effects against development of Mets among low intensity smokers. For high intensity smokers, lowering smoking intensity and smoking cessation are also necessary to prevent development of Mets.

• 한국산학기술학회논문지
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• 제20권2호
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• pp.662-672
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• 2019

본 연구는 한국 성인의 대사증후군과 신체활동, 식이 형태의 관계를 파악하기 위하여 2016년도 국민건강영양조사 원시자료를 이용한 2차분석 연구이다. 만 19세 이상 65세 미만이며 대상자 선정기준을 충족한 3,352명을 대상으로 복합표본 ${\chi}^2$-검증, t-검증, 로지스틱 회귀분석으로 자료를 분석하였다. 연구결과, 대사증후군 유병률은 남성 29.7%, 여성 16.7% 이었다. 남성의 경우, 저 신체활동군과 비교하여 고 신체활동군은 대사증후군에 이환될 가능성이 0.8배 증가하고(OR=0.8, p=.038), 지방을 많이 섭취할수록 대사증후군에 이환될 가능성이 0.98배 증가하였다(OR=0.98, p=.007). 여성의 경우, 저 신체활동군과 비교하여 고 신체활동군은 대사증후군에 이환될 가능성이 0.7배 증가하고(OR=0.71, p=.034), 탄수화물, 단백질, 지방 섭취 비율이 높을수록 대사증후군에 이환될 가능성이 각각 1.03배(OR=1.03, p<.001), 0.96배(OR=0.96, p=.009), 0.95배(OR=0.95, p<.001) 증가하였다. 본 연구결과를 바탕으로, 대사증후군 유병률이 급증하는 성인을 대상으로 정기적인 신체검진을 통해 대사증후군 위험집단을 선별하고, 선별된 위험집단을 대상으로 대상자의 특성을 반영하여 규칙적인 고강도 신체활동과 탄수화물, 단백질, 지방 섭취의 구체적인 지침을 제시하는 중재 프로그램이 개발 및 제공되어야 할 것이다.