• Title/Summary/Keyword: meta-regression analysis

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Effects of Taekwondo training on physical fitness factors in Korean elementary students: A systematic review and meta-analysis

  • Nam, Sang-Seok;Lim, Kiwon
    • Korean Journal of Exercise Nutrition
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    • v.23 no.1
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    • pp.36-47
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    • 2019
  • [Purpose] We conducted a meta-analysis to evaluate the effects of Taekwondo training on the physical fitness factors in Korean elementary students comprehensively and quantitatively. [Methods] We classified research studies published until November 2018 according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines and selected a total of 17 research items; a meta-analysis of these items was then conducted. We used the Comprehensive Meta-Analysis 3.0 and Review Manager 5.3 to analyze the mean effect size, study quality, and publication bias. [Results] Taekwondo training improved the cardiopulmonary endurance, muscle endurance, and power of the elementary students, but was not practical or less useful on other physical fitness factors. The meta-regression analysis of the cardiopulmonary endurance and power items showed that the effect size was large when the sample size was small. Therefore, it is necessary to consider the sample size in interpreting the effect size for these two items. Further, during correction of the publication bias for the power items, the improvement effect by Taekwondo training was eliminated. [Conclusion] Taekwondo training is helpful for improving the cardiopulmonary endurance and muscle endurance of Korean elementary students but is not useful for other physical fitness factors.

Arachnoid Plasty to Prevent and Reduce Chronic Subdural Hematoma after Clipping Surgery for Unruptured Intracranial Aneurysm : A Meta-Analysis

  • Jang, Kyoung Min;Choi, Hyun Ho;Nam, Taek Kyun;Park, Yong Sook;Kwon, Jeong Taik
    • Journal of Korean Neurosurgical Society
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    • v.63 no.4
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    • pp.455-462
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    • 2020
  • Objective : Recent studies have reported that arachnoid plasty (ARP) using gelatin sponges with fibrin glue reduced the occurrence of chronic subdural hematoma (CSDH) following clipping surgery for unruptured intracranial aneurysm (UIA). This meta-analysis was conducted to collate further evidence for the efficacy of ARP in preventing postoperative CSDH. Methods : Data of patients who underwent clipping surgery were extracted from PubMed, EMBASE, and Cochrane Central Register of Controlled Trials by two independent reviewers. A random effects model was used to investigate the efficacy of ARP by using odd ratios (ORs) and 95% confidence intervals (CIs). A meta-regression analysis for male sex was additionally preformed. Results : Data from six studies with 1715 patients were consecutively included. Meta-analysis revealed that ARP was significantly associated with lower rates of CSDH development after surgical clipping for UIA (ARP group vs. control group : 3.2% vs. 7.2%; OR, 0.40; 95% CI, 0.18-0.93; I2=44.3%; p=0.110). Meta-regression analysis did not highlight any modifying effect of the male sex on postoperative CSDH development (p=0.951). Conclusion : This meta-analysis indicated that ARP reduced the incidence rates of CSDH following clipping surgery for UIA. If feasible, ARP would be implemented as an additional surgical technique to prevent postoperative CSDH development during surgical clipping of UIA.

Anti-Diabetic Medications Do Not Influence Risk of Lung Cancer in Patients with Diabetes Mellitus: a Systematic Review and Meta-analysis

  • Nie, Shu-Ping;Chen, Hui;Zhuang, Mao-Qiang;Lu, Ming
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.16
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    • pp.6863-6869
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    • 2014
  • Objectives: Several preclinical and observational studies have shown that anti-diabetic medications (ADMs) may modify the risk of lung cancer. We performed a systematic review and meta-analysis evaluating the effect of metformin, sulfonylureas (SUs), thiazolidinediones (TZDs), and insulin on the risk of lung cancer in patients with diabetes mellitus (DM). Materials and Methods: We conducted a systematic search of Pubmed and Web of Science, up to August 20, 2013. We also searched the Conference Proceedings Citation Index (CPCI) and China National Knowledge Infrastructure (CNKI) for abstracts from major meetings. Fixed or random effect pooled measures were selected based on heterogeneity among studies, which was evaluated using Q test and the I2 of Higgins and Thompson. Meta-regression was used to explore the sources of between-study heterogeneity. Publication bias was analyzed by Begg's funnel plot and Egger's regression test. Associations were assessed by odds ratios (ORs) with 95% confidence intervals (CIs). Results: A total of 15 studies (11 cohort, 4 case-control) were included in this meta-analysis. In observational studies no significant association between metformin (n=11 studies; adjusted OR=0.99, 95%CI: 0.87-1.12), SUs (n=5 studies; adjusted OR=0.98, 95%CI: 0.79-1.22), or TZDs (n=7 studies; adjusted OR=0.92, 95%CI: 0.75-1.13), insulin (n=6 studies; adjusted OR=1.13, 95%CI: 0.79-1.62) use and risk of developing lung cancer was noted. There was considerable inherent heterogeneity between studies not explained by study design, setting, or location. Conclusions: Meta-analysis of existing studies does not support a protective or harmful association between ADMs use and risk of lung cancer in patients with DM. There was considerable heterogeneity across studies, and future, well-designed, prospective studies would be required for better understanding of any association.

A Meta-Analysis on the Correlation between Job Satisfaction, Turnover Intention and Organizational Commitment among Nurses

  • Lee, Hong-Ki;Myoun, Sungmin
    • Journal of the Korea Society of Computer and Information
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    • v.22 no.4
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    • pp.115-122
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    • 2017
  • The purpose of this study was to evaluate the effect of job satisfaction on turnover intention and organizational commitment in nurses through a systematic literature review and meta-analysis. For the study purpose, 26 studies were selected through a systematic process of using several databases and used to estimate the effect size of correlation between 3 variables. Meta-analysis was applied by usingcrandom effects model, and effect sizes on three types were calculated. Results are as follows. First, the effect size of correlation between job satisfaction and turnover intention is -.58. Second, the effect size of correlation between job satisfaction and organizational commitment is .77. Third, for the organizational commitment and turnover intention relationship, the effect of correlation is -0.68. Furthermore, publication bias analysis were assessed the results by using the funnel plot, Egger's regression test, fail-safe N, and trim-and-fill test. Based on these results, implications for the study were discussed.

Effects of Electrical Stimulation on Patients with Non-Specific Low Back Pain : A Meta-Analysis of Domestic Database (비특이적 만성 허리통증 환자에 대한 전기자극의 효과 : 국내 데이터베이스의 메타분석)

  • Lee, Jeong-Woo;Cho, Sung-Hyoun
    • Journal of The Korean Society of Integrative Medicine
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    • v.10 no.3
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    • pp.37-52
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    • 2022
  • Purpose : The purpose of this meta-analysis was to evaluate the effects of electrical stimulation on patients with non-specific low back pain. Methods : Domestic databases were gathered from studies that conducted clinical trials associated with electrical stimulation and its impact on pain of non-specific low back patients. A total of 681 studies were identified, with 12 studies satisfying the inclusion data. The studies consisted of patient, intervention, comparison, outcome, and study design (PICO-SD). The search outcomes were items associated with low back pain. Cochrane risk of bias 2 (RoB 2) was used to evaluate the quality of 12 randomized controlled trials. Effect sizes (Hedges's g) in this study were computed as the corrected standard mean difference (SMD). A random-effect model was used to analyze the effect size because of the high heterogeneity among the studies. Egger's regression and 'trim-and-fill' tests were carried out to analyze the publication bias. Cumulative meta-analysis and sensitivity analysis were conducted to analyze the effect according to the sample size and the consistency of the effect size. Results : The following factors had a large overall effect size (Hedges's g=1.28, 95 % CI=.20~2.36) involving electrical stimulation on non-specific low back pain. The subgroup analysis all showed a statistical difference in the types of study design, electrical stimulation, and assessment tool. No statistically significant difference was found in the meta-regression analysis. Publican bias was found in the data. Conclusion : The findings in this study indicate that electrical stimulation interventions have a positive effect on patients with non-specific low back pain. However, due to the low quality of studies and publication bias, the results of our study should be interpreted cautiously.

Impact of Humectants on Physicochemical and Functional Properties of Jerky: A Meta-Analysis

  • Shine Htet Aung;Ki-Chang Nam
    • Food Science of Animal Resources
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    • v.44 no.2
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    • pp.464-482
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    • 2024
  • This study aimed to determine the effects of humectants on moisture content, water activity, tenderness, color, microbiological analysis, protein denaturation, and oxidation of jerky. A thorough search for papers published in scientific journals that examined the impacts of humectants on jerky was carried out using Web of Science, Google Scholar, PubMed, and Science Direct. Only 14 studies matched inclusion requirements. They were used in the meta-analysis to synthesise quantitative findings. In the current investigation, jerky produced with beef, poultry, goat, or pork was used. The standardised mean difference (SMD) between treatments with humectants and controls was examined to investigate the effects of humectants using random-effects models. Heterogeneity was investigated using meta-regression. A subgroup analysis was carried out for significant factors. Results revealed that the addition of humectants had no significant impact on water activity, pH, fat, ash, CIE L*, or CIE a* (p>0.05). However, humectant addition significantly increased moisture (SMD=1.28, p<0.05), CIE b* (SMD=1.67, p<0.05), and overall acceptability (SMD=1.73, p<0.05). It significantly decreased metmyoglobin (SMD=-0.96, p<0.05), shear force (SMD=-0.84, p<0.05), and protein (SMD=-1.61, p<0.05). However, it was difficult to get a firm conclusion about how humectants affected the myofibrillar fragmentation index, total plate count, and 2-thiobarbituric acid-reactive substances because there were fewer than ten studies. To sum up, the proper use of humectants in jerky demands careful attention to both type and quantity, needing a delicate balancing act with other contributing factors.

The effect of aromatherapy on pain in individuals with diabetes: a systematic review and meta-analysis

  • Mi-Kyoung Cho;Mi Young Kim
    • Journal of Korean Biological Nursing Science
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    • v.26 no.2
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    • pp.71-82
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    • 2024
  • Purpose: This study systematically analyzed the impact of aromatherapy on pain in individuals with diabetes. Methods: A search was performed in seven electronic databases based on the PICO-SD (Population, Intervention, Comparison, Outcome, Study Design) framework. The population (P) of interest was individuals with diabetes, and the intervention (I) included aromatherapy targeting pain reduction. The comparison (C) consisted of control groups that received no intervention, another intervention, or usual care. The outcome (O) measured was pain. The quality of the selected literature was assessed using the Joanna Briggs Institute checklist. In MIX 2.0 Pro, the pooled overall effect of pain was calculated using Hedge's g and a random-effects model, and heterogeneity was calculated using the Q statistic and Higgin's I2 values. Meta-regression and exclusion sensitivity analyses were performed. Results: Five articles and seven studies were included, showing a significant pooled overall effect of aromatherapy on diabetes-related pain (Hedge's g = -1.83, 95% CI: -2.76 to -0.91). Meta-regression demonstrated that effectiveness in reducing pain was associated with studies conducted in West Asia, those with IRB approval, and those receiving funding. Additionally, interventions involving subjects under 60, lavender oil (vs. turpentine oil or blended oils), massage therapy (vs. topical application), fewer hours per session, and more repeated measurements (vs. pre/post measurements) were associated with pain reduction. Conclusion: Aromatherapy, especially with lavender oil, effectively manages diabetes-related pain. Short-duration massage application is also effective. A personalized selection of oil type and application method could optimize therapeutic outcomes for individuals with diabetes.

The Meta-Analysis on Effects of Education of Python for Elementary School Students (초등학생 대상 파이썬(Python) 활용 교육의 효과에 대한 메타분석)

  • Yoon, So Hee;Jang, Bong Seok
    • Journal of Industrial Convergence
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    • v.18 no.5
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    • pp.97-101
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    • 2020
  • This study intended to analyze effects of education of python through meta-analysis. The researcher selected five primary studies reporting statistical data after implementing education of python in elementary classroom settings. Three research questions were stated. What is the total effect size of education of python? What are effect sizes of publication type, dependent variable, and etc.? What are results of meta-regression analysis by grade level, period, and etc.? Findings are as follows. The overall effect size was .598, which is medium. For categorical variables, the effect size of peer-reviewed journal articles was larger than theses. The effect size of affective domain was larger than student achievement and cognitive domain. For meta-regression analysis, education of python was more effective as the period and duration of the program increased. Finally, discussions and recommendations including qualitative investigation on affective domain and program management considering characteristics were presented regarding research findings.

Effect of Laughter Therapy on Healthy Life: A Meta-analysis (웃음요법이 건강한 삶에 미치는 효과: 메타분석)

  • Hwang, Sung-Ho;Jeong, Hyeon-Cheol;Hwang, Ji-Won
    • Journal of the Korea Convergence Society
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    • v.10 no.9
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    • pp.291-299
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    • 2019
  • The purpose of this study is to identify the effects of laughter therapy on healthy life of human through meta-analysis of literature. Based on domestic and foreign academic databases, 495 foreign and 199 domestic literature were reviewed focusing on "quality of life," as the ultimate goal of health. The final seven literature were extracted. Analyses was performed in R version 3.5.1. Significant differences (SMD=0.23, p<0.01) were shown in the pre-post comparisons of experimental groups using the mean difference (effects size) analysis of the extracted samples. Significant results were not shown in meta regression analyses setting explanatory variables as 'treatment sessions and durations' and outcome variables as 'treatment effects of laughter therapy'. This study is meaningful in comparative analyses of pre-post experimental groups to establish 'laughter therapy' has a significant effect on improving 'quality of life' and is a useful intervention method, especially for older people, and older women with depression.

The anti-diabetic effect of propolis using Hedges' standardized mean difference (헤지의 표준화된 평균차를 이용한 프로폴리스의 항-당뇨 효과)

  • Kim, Mi-Jin;Choi, Ki-Heon
    • Journal of the Korean Data and Information Science Society
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    • v.21 no.3
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    • pp.447-459
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    • 2010
  • The present study was carried out to summarize the effect of propolis in the diabetic rats by meta-analysis related studies. The association measure to test effect of propolis was Hedges's standardized mean difference between group of rats induced streptozotocin(STZ) or alloxan and group of rats induced STZ or alloxan treated with propolis about the considered 4 effect factors. In this particular fixed-effect model, blood glucose, Cholesterol, Triglyceride were significantly reduce. The case of heterogenous variable such as body weight, blood glucose, cholesterol, triglyceride, random-effect model was applied. In this model, blood glucose, triglyceride were decreased significantly in propolis treated group. According to the meta-regression analysis, period of injection was significant for body weight and blood glucose, cholesterol.