• Asian Pacific Journal of Cancer Prevention
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• 제15권13호
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• pp.5161-5166
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• 2014

Our aim was to access the association between recreational physical activity (RPA) and risk of ovarian cancer (OC). The studies were retrieved from the PubMed and Embase databases up to February 20th, 2014. Risk ratios (OR) and 95% confidence intervals (CI) were used to estimate effect sizes. Random-effects or fixed-effects models were used to pool the data. The trim and fill method was applied for sensitivity analysis. Begg's rank correlation test and Egger's regression asymmetry test were employed to assess the publication bias. A total of 6 studies (435398 participants including 2983 OC patients) were included in this meta-analysis. The overall estimate indicated that there was weakly inverse association between RPA and OC risk (RR=0.90, 95%CI: 0.72-1.12, p=0.335). Meanwhile, for prospective cohort studies, a result consistent with the overall estimate was obtained (RR=1.12, 95% CI: 0.88-1.42, p=0.356). However, for case control studies, the pooled estimate of RR was 0.76 (95%CI: 0.64-0.90, p=0.002), indicating a clear significant association between RPA and OC risk. In addition, the sensitivity analysis indicated a significant link between RPA and risk of OC after removing Lahmann's study (RR=0.80, 95% CI: 0.68-0.93, p=0.004). No significant publication bias was found (Begg's test: p=1.00; Egger's test: p=0.817). In conclusion, our meta-analysis indicated a weakly inverse relationship between RPA and the occurrence of OC.

• 한국컴퓨터정보학회논문지
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• 제23권10호
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• pp.157-164
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• 2018

The purpose of this study was to investigate the effect of empowerment in nurses through a systematic literature review and meta-analysis. 23 studies were collected through a systematic process of using several databases such as NDSL, DBPIA, and KISS. Keywords included 'nurse', 'empowerment', and 'correlation' and the reviewed articles were published from 2002 to 2017. In order to estimate the effect size of correlation between empowerment, 3 variables (job satisfaction, organizational commitment, and nursing performance) were considered. Using the R program, meta-analysis was calculated by using random effects model, and effect sizes on three types were estimated. As the result, it was found, first, the effect size of correlation between job satisfaction and empowerment is .50. Second, the effect size of correlation between organizational commitment and empowerment is .45. Third, for the nursing performance and empowerment relationship, the effect of correlation is 0.50. Also, Egger's regression test, fail-safe N, trim-and-fill test, and funnel plot were showed to evaluate the results. These results highlights the need for appropriate policies of the relationship between empowerment and job satisfaction, organizational commitment and nursing performance in nurses.

• Clinical and Experimental Pediatrics
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• 제64권8호
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• pp.415-421
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• 2021

Background: Antibiotic resistance is associated with longer hospitalizations, higher treatment costs, and increased morbidity and mortality rates. Purpose: This study aimed to determine the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) in Iranian children. Methods: International databases, including Web of Science, PubMed, Embase, and Scopus, and Iranian databases, including Scientific Information Database (www.sid.ir), Magiran, and Iranian Database for Medical Literature (idml.research.ac.ir), were systematically searched for articles published between January 2000 and August 2019. Sources of heterogeneity were determined using subgroup analysis and meta-regression. Results: Overall, 343 studies were identified; of them, 20 were included in the meta-analysis to estimate the pooled prevalence. The pooled prevalence of MRSA was 42% (95% confidence interval [CI], 29-55) among culture-positive cases of S. aureus, 51% (95% CI, 39-62) in hospitalized children, and 14% (95% CI, 0.05-27) in healthy children. Conclusion: The overall pooled prevalence of MRSA in children was 42%. Appropriate infection control measures and effective antibiotic therapy are needed.

• 한국가족관계학회지
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• 제22권1호
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• pp.63-85
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• 2017

Objectives: The purpose of this study was to conduct a meta analysis of the previous studies on parental factors related to psychological and social maladjustment of school children and to examine the moderate effects of publication year using the meta-regression analysis. Method: Subjects of studies was academic journals and thesis published on 1996-Feb. 2016. Final result of selection was 353(122 journal articles, 231 master's thesis & dissertations) and total number of sampling was 126,776 school children. Results: Parental factors had medium effect sizes on psychological and social maladjustment of school children. Parental risk factors had bigger effect size than protective factors on children's maladjustment. There were a tendency that effect size of some parental factors were increased as publish year went by. Conclusions: Attachment, positive communication, and positive marital relationship were major protective factors which had reduced maladjustment of children. Psychological control and negative marital relationship were the strongest risk factors. The impact on parental factors on maladjustment of children were getting stronger recently.

• 한국산학기술학회논문지
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• 제17권11호
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• pp.271-284
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• 2016

본 연구는 임부의 산전우울에 대한 인지행동치료 중재의 효과를 검증하기 위해 수행된 체계적 문헌고찰 및 메타분석 연구이다. 데이터베이스는 CINAHL, PubMed, EMBASE 및 Koreamed, 국회도서관, 한국학술정보(Korean studies Information Service System, KISS), 한국의학논문데이터베이스 등 국내외 domain을 활용하였다. 검색은 ((Perinatal OR Antenatal OR Antepartum OR Pregnant) AND Depression) AND Women AND (CBT OR (Cognitive behavioral AND (Therapy OR Treatment)))와 '산전우울', '임부', '인지행동치료' 등의 검색어로 2016년 5월까지 출판된 문헌을 검토하였다. 분석은 R을 이용한 임의효과모형을 적용하여 산전우울과 불안의 효과크기를 각각 산출하였으며, 효과크기의 이질성을 검증하기위해 메타 ANOVA를 활용하여 조절효과분석을 실시하였다. 그리고 funnel plot, Egger's regression test, fail-safe N, trim-and-fill 분석을 활용한 출간오류분석과 민감성 분석을 실시하여 전체 연구 결과의 타당성을 검증하였다. 연구결과 총 180편의 문헌이 검색되었으며, 선택배제기준에 따라 최종적으로는 clinical trials 16편을 분석하였다. 분석에 포함된 개별문헌은 Scottish Intercollegiate Guideline Network (SIGN)의 checklist를 통해 비뚤림 위험을 평가하였으며, 대체로 비뚤림 위험은 낮았다. 연구결과 본 연구에서 중재의 산전우울에 대한 효과크기는 Hedges' g=-0.55(95% CI: -0.76~-0.33)로 통계적으로 유의하게 낮았으며, 불안에 대한 효과크기는 Hedges' g=-0.20(95% CI: -0.48~-0.08)이었으나, 통계적으로 유의한 차이는 없었다. 문헌의 이질성, 출판오류의 위험성 등은 낮았다. 본 메타분석결과에 의하면 인지행동치료는 임신부의 산전우울 증세 완화에 보통 정도의 효과가 있음이 밝혀졌다.

• Asian Pacific Journal of Cancer Prevention
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• 제15권9호
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• pp.4071-4077
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• 2014

Background: The effects of CYP1A1 gene polymorphisms on the risk of bladder cancer (BC) remain controversial. We carried out a meta-analysis to clarify the role of CYP1A1 gene polymorphisms in BC. Material and Methods: A comprehensive literature search was conducted up to November 20, 2013. Odds ratios (ORs) with 95% confidence intervals (CIs) were used to estimate the strength of the association. Meta-regression, subgroup analysis, sensitivity analysis and publication bias were also performed. Results: Eight studies involving 1,059 BC cases and 1,061 controls were included. The meta-analysis showed that there was no significant association between the two common mutations of CYP1A1 and BC risk. For the I1e462Val A/G polymorphism with GG vs. AA the OR was 1.47 (95 % CI= 0.70-3.07, P =0.308). For the MspI T/C polymorphism, though a slight trend was found this was not statistically nonsignificant (CC vs.TT, OR = 1.24, 95 % CI= 0.98-1.58, P =0.078). Subgroup analyses by ethnicity also found no obvious association between CYP1A1 and BC risk. Conclusion: The present meta-analysis suggests that CYP1A1 polymorphism is not associated with bladder cancer risk.

• Asian Pacific Journal of Cancer Prevention
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• 제15권21호
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• pp.9085-9091
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• 2014

Background: Epidemiology studies have shown an inconclusive relationship between phytoestrogen intake and ovarian cancer risk and there have been no relevant meta-analyses directly regarding this topic. The purpose of the present meta-analysis was therefore to investigate any association between phytoestrogen intake and ovarian cancer in detail. Materials and Methods: We conducted a search of PubMed, EMBASE, EBSCO, the Cochrane Library, CNKI and Chinese Biomedical Database (up to April 2014) using common keywords for studies that focused on phytoestrogen and ovarian cancer risk. Study-specific risk estimates (RRs) were pooled using fixed effect or random-effect models. Results: Ten epidemiologic studies were finally included in the meta-analysis. The total results indicated higher phytoestrogen intake was associated with a reduced ovarian cancer risk (RR, 0.70; 95%CI: 0.56-0.87). The association was similar in sensitivity analysis. Meta regression analysis demonstrated sources and possibly types and regions as heterogeneous factors. Subgroup analysis of types, sources and regions showed that isoflavones (RR: 0.63; 95%CI: 0.46, 0.86), soy foods (RR: 0.51; 95%CI: 0.39, 0.68) and an Asian diet (RR: 0.48; 95%CI: 0.37, 0.63) intake could reduce the incidence of ovarian cancer. Conclusions: Our findings show possible protection by phytoestrogens against ovarian cancer. We emphasize specific phytoestrogens from soy foods, but not all could reduce the risk. The habit of plentiful phytoestrogen intake by Asians is worthy to recommendation. However, we still need additional larger well designed observational studies to fully characterize underlying associations.

• 한국융합학회논문지
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• 제7권5호
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• pp.145-153
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• 2016

이 연구는 메타분석을 활용하여 현재 다양한 영역에서 실시되고 있는 수용전념치료 프로그램의 효과에 대해 종합적으로 평가하였다. 메타분석은 통계적인 방법을 활용하여 개입의 크기와 방향을 제시한다. 이를 통해 개입에 대한 종합적 분석이 가능하다. 논문의 선정기준을 통해 총 43편의 연구물을 분석 대상으로 선정하였다. 선정된 33편의 연구물에서 183개의 효과크기를 종합하여 전체효과크기, 하위집단별 효과크기, 메타회귀분석 결과를 제시하였다. 그 결과 수용전념치료 프로그램의 전체 효과크기는 0.704로 나타났다. 이는 중간 이상의 효과크기를 의미한다. 수용전념치료의 효과 영역에 따라 효과크기를 비교한 결과, 정의적 영역, 인지적 영역, 행동적 영역 순으로 효과크기를 나타냈다. 참가자의 특성에 따른 효과크기를 비교한 결과 첫째, 성별에 따른 분석결과, 혼성 집단, 여성 집단, 남성 집단 순으로 효과크기를 나타냈다. 둘째 연령에 따른 분석 결과 일반성인, 대학생(대학원생), 청소년 순이었다. 이러한 연구 결과를 바탕으로 후속연구와 향후 프로그램 운영에 대한 시사점을 논의하였다.

• 소성∙가공
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• 제29권5호
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• pp.241-250
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• 2020

In this study, the methodology of the springback prediction of automotive parts applied 3rd generation AHSS was investigated using the response surface model analysis based on a regression model, and the meta model analysis based on a Kriging model. To design the learning data set for constructing the springback prediction models, and the experimental design was conducted at three levels for each processing variable using the definitive screening designs method. The hat-shaped member, which is the basic shape of the member parts, was selected and the springback values were measured for each processing type and processing variable using the finite element analysis. When the nonlinearity of the variables is small during the hat-shaped member forming, the response surface model and the meta model can provide the same processing parameter. However, the accuracy of the springback prediction of the meta model is better than the response surface model. Even in the case of the simple shape parts forming, the springback prediction accuracy of the meta model is better than that of the response surface model, when more variables are considered and the nonlinearity effect of the variables is large. The efficient global optimization algorithm-based Kriging is appropriate in resolving the high computational complexity optimization problems such as developing automotive parts.

• 한국문헌정보학회지
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• 제43권4호
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• pp.117-137
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• 2009

본 연구는 도서관의 경제적 가치를 실증적으로 측정한 국내 외 42개의 선행연구들을 수집 정리하고, 상이하게 나타난 투자수익률이나 비용편익비율을 어떻게 해석해야 하는지를 메타분석을 통해서 통계적인 방법으로 파악하고자 한다. 메타분석법은 도서관의 경제적 가치측정 연구들이 제시한 수치를 통계적인 방법으로 분석하여 그 결과를 객관적으로 종합하기 위하여 적용되었다. 선행연구를 토대로 6개의 변인(조사시점, 도서관 유형, 연구방법, 혜택범위, 서비스범위, 1인당 GDP)을 도출하였고, 이들을 대상으로 6개의 가설을 설정하였다. 메타 회귀분석 결과, 혜택의 범위(직접효과, 간접효과) 및 국민 1인당 GDP의 수준에 따라 투자수익률의 일관성 있는 예측이 가능하다는 결과가 나타났다. 본 연구는 도서관의 경제적 가치 분야에서 수행된 국내 최초의 메타분석으로서, 이 분야의 연구에서 도출된 결과를 정책결정에 적용하는 데 도움이 될 것으로 기대된다.