• Title/Summary/Keyword: meta-regression

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Revisited meta-analysis of the effects of practical reasoning instruction on students' achievements in Home Economics classes (가정과수업에서 실천적추론수업의 학생성취에 대한 효과성 연구의 메타분석)

  • Yu, Nan Sook
    • Journal of Korean Home Economics Education Association
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    • v.30 no.3
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    • pp.151-173
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    • 2018
  • The purposes of this study was to identify the magnitude and direction of the effects of Practical Reasoning Instruction (PRI) on students' achievements in Home Economics classes using the meta-analysis method and to examine whether the effects of PRI vary across publication status, study design, year of the studies, school level, gender of students, type of students' achievements, content area, location where the interventions of PRI were conducted, and duration. Thirty-four primary studies with 44 effect sizes were analyzed with calculation method of Becker(1988). A funnel plot method result revealed no publication bias. The results of this meta-analysis are as follows. First, PRI was more effective than traditional instruction on students' achievements. A summary statistic was 0.60 with a standard error of .074, which means that an increase of about two-third of a standard deviation beyond what would be expected from traditional instruction was gained from PRI intervention. Second, categorical and regression analyses were employed to find the sources of variance and moderators that predict the effects of PRI. The moderator analyses revealed no statistically significant effects of publication status, study design, school level, gender of students, type of students' achievements, and duration. Content area, location where the interventions of PRI were revealed to be moderators. It was concluded that PRI was effective in improving students' achievements regardless of publication status, study design, year of the studies, school level, gender of students, type of student achievement, and duration.

Estrogen Receptor Alpha Gene Polymorphisms and Breast Cancer Risk: a Case-control Study with Meta-analysis Combined

  • Lu, Hong;Chen, Dong;Hu, Li-Ping;Zhou, Lian-Lian;Xu, Hui-Ying;Bai, Yong-Heng;Lin, Xiang-Yang
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.11
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    • pp.6743-6749
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    • 2013
  • Molecular epidemiological studies have shown that gene polymorphisms of estrogen receptor alpha gene (ESR-${\alpha}$) are associated with breast cancer risk. However, previous results from many molecular studies have been inconsistent. In this study, we examined two polymorphisms (PvuII and XbaI RFLPs) of the ESR-${\alpha}$ gene in 542 breast cancer cases and 1,016 controls from China. Associations between the polymorphisms and breast cancer risk were calculated with an unconditional logistic regression model. Linkage disequilibrium and haplotypes were analyzed with the SHEsis software. In addition, we also performed a systematic meta-analysis of 24 published studies evaluating the association. No significant associations were found between the PvuII polymorphism and breast cancer risk. However, a significantly decreased risk of breast cancer was observed among carriers of the XbaI 'G' allele (age-adjusted OR = 0.80; 95% CI = 0.66- 0.97) compared with carriers of the 'A' allele. Haplotype analysis showed significantly decreased cancer risk for carriers of the 'CG' haplotype (OR = 0.79; 95% CI = 0.66- 0.96). In the systematic meta-analysis, the XbaI 'G' allele was associated with an overall significantly decreased risk of breast cancer (OR = 0.90, 95% CI = 0.82- 1.00). In addition, the PvuII 'C' allele showed a 0.96- fold decreased disease risk (95% CI = 0.92- 0.99). In subgroup analysis, an association between the PvuII 'C' and XbaI 'G' alleles and breast cancer risk was significant in Asians ('C' vs. 'T': OR = 0.93, 95% CI = 0.85- 1.00; 'G' vs. 'A': OR = 0.82, 95% CI = 0.68- 0.98), but not in Euro-Americans. Thus, our results provide evidence that ESR-${\alpha}$ polymorphisms are associated with susceptibility to breast cancer. These associations may largely depend on population characteristics and geographic location.

Tissue Adequacy and Safety of Percutaneous Transthoracic Needle Biopsy for Molecular Analysis in Non-Small Cell Lung Cancer: A Systematic Review and Meta-analysis

  • Bo Da Nam;Soon Ho Yoon;Hyunsook Hong;Jung Hwa Hwang;Jin Mo Goo;Suyeon Park
    • Korean Journal of Radiology
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    • v.22 no.12
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    • pp.2082-2093
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    • 2021
  • Objective: We conducted a systematic review and meta-analysis of the tissue adequacy and complication rates of percutaneous transthoracic needle biopsy (PTNB) for molecular analysis in patients with non-small cell lung cancer (NSCLC). Materials and Methods: We performed a literature search of the OVID-MEDLINE and Embase databases to identify original studies on the tissue adequacy and complication rates of PTNB for molecular analysis in patients with NSCLC published between January 2005 and January 2020. Inverse variance and random-effects models were used to evaluate and acquire meta-analytic estimates of the outcomes. To explore heterogeneity across the studies, univariable and multivariable metaregression analyses were performed. Results: A total of 21 studies with 2232 biopsies (initial biopsy, 8 studies; rebiopsy after therapy, 13 studies) were included. The pooled rates of tissue adequacy and complications were 89.3% (95% confidence interval [CI]: 85.6%-92.6%; I2 = 0.81) and 17.3% (95% CI: 12.1%-23.1%; I2 = 0.89), respectively. These rates were 93.5% and 22.2% for the initial biopsies and 86.2% and 16.8% for the rebiopsies, respectively. Severe complications, including pneumothorax requiring chest tube placement and massive hemoptysis, occurred in 0.7% of the cases (95% CI: 0%-2.2%; I2 = 0.67). Multivariable meta-regression analysis showed that the tissue adequacy rate was not significantly lower in studies on rebiopsies (p = 0.058). The complication rate was significantly higher in studies that preferentially included older adults (p = 0.001). Conclusion: PTNB demonstrated an average tissue adequacy rate of 89.3% for molecular analysis in patients with NSCLC, with a complication rate of 17.3%. PTNB is a generally safe and effective diagnostic procedure for obtaining tissue samples for molecular analysis in NSCLC. Rebiopsy may be performed actively with an acceptable risk of complications if clinically required.

The Effect of Senior Elementary School Students' Emotional Perception Clarity, Emotion Regulation, and Family Relationship on Non-Suicidal Self-Injury and Depression (초등학생 고학년의 정서인식 명확성, 정서조절전략, 가족관계가 비자살적 자해 및 우울에 미치는 영향)

  • Shin, Ji-hye;Kim, Suk-Sun
    • Research in Community and Public Health Nursing
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    • v.32 no.4
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    • pp.457-466
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    • 2021
  • Purpose: The purpose of this study was to examine the correlations among emotional perception clarity, emotion regulation, family relationship, non-suicidal self-injury, and depression, and to determine associated factors of non-suicidal self-injury and depression for senior elementary school students. Methods: Data were collected from 150 early adolescences in K region, Korea. A self-report questionnaire consisted of Trait Meta-Mood Scale, Cognitive Emotion Regulation Questionnaire, Family Relationship Assessment Scale, Functional Assessment of Self-Mutilation, and Children's Depression Inventory. The data were analyzed using t-test, Pearson's correlation coefficient, logistic regression, and multiple regression analysis. Results: Non-suicidal self-injury and depression were positively associated with maladaptive emotion regulation strategy and family conflict, but negatively related to emotional perception clarity and family support. Adaptive emotion regulation strategy and family togetherness were only significantly correlated with depression. In logistic regression analysis, significant predictors of non-suicidal self-injury were emotional perception clarity, maladaptive emotion regulation strategy, and family support. Multiple regression analysis found that significant factors of depression were adaptive and maladaptive emotion regulation strategies, which explained 38.0% of the variance. Conclusion: Our study findings suggest that targeted intervention to reinforce the adaptive emotion regulation strategy and family relationship may prevent non-suicidal self-injury, and depression for senior elementary school students.

Neuro-fuzzy optimisation to model the phenomenon of failure by punching of a slab-column connection without shear reinforcement

  • Hafidi, Mariam;Kharchi, Fattoum;Lefkir, Abdelouhab
    • Structural Engineering and Mechanics
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    • v.47 no.5
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    • pp.679-700
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    • 2013
  • Two new predictive design methods are presented in this study. The first is a hybrid method, called neuro-fuzzy, based on neural networks with fuzzy learning. A total of 280 experimental datasets obtained from the literature concerning concentric punching shear tests of reinforced concrete slab-column connections without shear reinforcement were used to test the model (194 for experimentation and 86 for validation) and were endorsed by statistical validation criteria. The punching shear strength predicted by the neuro-fuzzy model was compared with those predicted by current models of punching shear, widely used in the design practice, such as ACI 318-08, SIA262 and CBA93. The neuro-fuzzy model showed high predictive accuracy of resistance to punching according to all of the relevant codes. A second, more user-friendly design method is presented based on a predictive linear regression model that supports all the geometric and material parameters involved in predicting punching shear. Despite its simplicity, this formulation showed accuracy equivalent to that of the neuro-fuzzy model.

Time-history analysis based optimal design of space trusses: the CMA evolution strategy approach using GRNN and WA

  • Kaveh, A.;Fahimi-Farzam, M.;Kalateh-Ahani, M.
    • Structural Engineering and Mechanics
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    • v.44 no.3
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    • pp.379-403
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    • 2012
  • In recent years, the need for optimal design of structures under time-history loading aroused great attention in researchers. The main problem in this field is the extremely high computational demand of time-history analyses, which may convert the solution algorithm to an illogical one. In this paper, a new framework is developed to solve the size optimization problem of steel truss structures subjected to ground motions. In order to solve this problem, the covariance matrix adaptation evolution strategy algorithm is employed for the optimization procedure, while a generalized regression neural network is utilized as a meta-model for fitness approximation. Moreover, the computational cost of time-history analysis is decreased through a wavelet analysis. Capability and efficiency of the proposed framework is investigated via two design examples, comprising of a tower truss and a footbridge truss.

Comparative Experimental Study on the Evaluation of the Unit-water Content of Mortar According to the Structure of the Deep Learning Model (딥러닝 모델 구조에 따른 모르타르의 단위수량 평가에 대한 비교 실험 연구)

  • Cho, Yang-Je;Yu, Seung-Hwan;Yang, Hyun-Min;Yoon, Jong-Wan;Park, Tae-Joon;Lee, Han-Seung
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2021.11a
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    • pp.8-9
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    • 2021
  • The unit-water content of concrete is one of the important factors in determining the quality of concrete and is directly related to the durability of the construction structure, and the current method of measuring the unit-water content of concrete is applied by the Air Meta Act and the Electrostatic Capacity Act. However, there are complex and time-consuming problems with measurement methods. Therefore, high frequency moisture sensor was used for quick and high measurement, and unit-water content of mortar was evaluated through machine running and deep running based on measurement big data. The multi-input deep learning model is as accurate as 24.25% higher than the OLS linear regression model, which shows that deep learning can more effectively identify the nonlinear relationship between high-frequency moisture sensor data and unit quantity than linear regression.

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Analysis of Nursing Studies on Hardiness Published in Korea (강인성에 대한 국내 간호논문 분석)

  • Kim, Young-Ock
    • Korean Journal of Adult Nursing
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    • v.16 no.1
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    • pp.27-36
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    • 2004
  • Purpose: The purpose of this study was to identify patterns and trends of hardiness studies and to suggest the direction of further research. Method : Forty-seven hardiness studies were collected through internet searching and were reviewed by some criteria. Result : The results showed that hardiness studies have increased rapidly since 1990's. Eighteen studies were thesis' for degrees and others were for non-degree research studies. All studies employed the non-experimental design, particularly correlational studies. In the sampling method, all studies used non-probability sampling. Most commonly used instrument for hardiness measurement was Pollock(1986)'s HRHS. In the majority of research, hardiness was treated both as a composite measure and 3 subscales. Hardiness-related concepts were 27 and classified into 5 categories such as health behavior, stress, adaptation, support, and others. Most common statistical technique was Pearson's correlation coefficient, followed by regression, ANOVA, path analysis. Conclusion : To be utilized as practical nursing knowledge, hardiness studies should be done with more empirical analysis such as experimental research, and Meta-analysis is needed to compare the effect size and significance of composit and 3 subscales of hardiness construct.

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A Study on the Acoustic Analysis Method of the External Ear Canal Using DICOM Images (DICOM 영상을 이용한 외이도 음향해석 방법에 관한 연구)

  • Kim, Hyeong-Gyun
    • Journal of the Korea Convergence Society
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    • v.10 no.3
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    • pp.73-79
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    • 2019
  • This study simulated external ear canal modeling with different external ear canal lengths, vertical flexion angles, and inner/outer diameter ratios using digital imaging and communications in medicine(DICOM) of the head temporal region and measured the acoustic sensitivity. The experiment was performed by increasing the audible frequency for humans by 200 Hz and expressing the frequency constantly transmitted at 1 Pa as the eardrum acoustic volume and presented the measurements by linear and quadratic curve regression analysis. The results showed that the longer the external ear canal length and the higher the ratio of the outer/inner diameter, the faster the acoustic response at lower frequencies. The acoustic sensitivity correlation of the meta-model using regression analysis showed a 77% influence by the external ear canal length and 5% by the external/internal diameter ratio, while the vertical flexion angle did not show a significant relationship. This showed that auditory acoustic sensitivity of humans is a factor that reacts faster at a low frequency when the external ear canal length is longer and when the difference between the outer and inner diameter is higher.

Protected versus Unprotected Carotid Artery Stenting : Meta-Analysis of the Current Literature

  • Cho, Young Dae;Kim, Sung-Eun;Lim, Jeong Wook;Choi, Hyuk Jai;Cho, Yong Jun;Jeon, Jin Pyeong
    • Journal of Korean Neurosurgical Society
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    • v.61 no.4
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    • pp.458-466
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    • 2018
  • Objective : To compare peri-operative any symptomatic stroke after carotid angioplasty and stenting (CAS), based on the application or absence of a cerebral protection device. Methods : A systematic literature review using PubMed, Embase, and the Cochrane Central was done across an online data base from January 1995 to October 2016. Procedures which were performed due to carotid dissection or aneurysm, procedures using covered stents or conducted in an emergency, were excluded. The primary endpoint was perioperative any symptomatic stroke within 30 days after the procedure. A fixed effect model was used in cases of heterogeneity less than 50%. Results : In the 25 articles included in this study, the number of stroke events was 326 (2.0%) in protected CAS and 142 (3.4%) in unprotected CAS. The use of cerebral protection device significantly decreased stroke after CAS (odds ratio [OR] 0.633, 95% confidence interval [CI] 0.479-0.837, p=0.001). In the publication bias analysis, Egger's regression test disclosed that the intercept was -0.317 (95% CI -1.015-0.382, p=0.358). Regarding symptomatic patients (four studies, 539 CAS procedures), the number of stroke was six (1.7%) in protected CAS and 11 (5.7%) in unprotected CAS. The protective effect against stroke events by cerebral protection device did not have a statistical significance (OR 0.455, 95% CI 0.151-1.366, p=0.160). Conclusion : The use of protection device significantly decreased stroke after CAS. However, its efficacy was not demonstrated in symptomatic patients. Routine use of protection device during CAS should be critically assessed before mandatory use.