• 대한치료과학회지
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• 제10권2호
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• pp.13-20
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• 2018

Objective: To investigate the effects of a brain fitness exercise on the cognitive function of patients with dementia. Method: Forty-six elderly adults diagnosed with dementia were randomly allocated to the study or control group (n=23 per group). The study and control groups performed a brain fitness and regular exercise, respectively, for 40 minutes a day, three times a week for four weeks. We examined cognitive capacity using MMSE-K, cognitive strength, judgment time, and mental workload scores before and after intervention. Results: The study group showed significant improvements in all variables. In addition, the control group showed a significant improvement in brain stress. We found that there was a significant improvement in the study group when compared with the control group in all variables. Conclusion: Based on these results, we suggest that brain fitness exercise would be effective in improving cognitive functions of dementia patients.

• 대한물리의학회지
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• 제14권4호
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• pp.115-123
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• 2019

PURPOSE: This study compared the scores of the Mini-Mental State Examination-Korean version (MMSE-K) and Korean version Montreal Cognitive Assessment (K-MOCA), which assess cognitive function, the Fugl- Meyer Upper-Extremity Assessment (FMA), which assess the upper extremity function; and Modified Barthel Index (MBI), which that assesses activities of daily living among patients receiving inpatient treatment following a diagnosis of stroke to determine the correlations among MMSE-K, K-MOCA, FMA, and MBI. METHODS: The study assessed the cognitive function using the MMSE-K and K-MOCA, upper extremity function using FMA, and activities of daily living using MBI. The data were analyzed using Pearson's correlation analysis and multiple regression analysis. RESULTS: An analysis of the differences in the MMSE-K, K-MOCA, MBI, and FMA scores according to the affected side, revealed differences in the, K-MOCA scores according to the affected side, where patients with right hemiplegia showed better cognitive function (p <.05). Correlation analysis among MMSE-K, K-MOCA, FMA, and MBI Showed significant correlations (p <.05). The results indicate that those with higher cognitive and upper extremity functions had higher performance of activities of daily living. CONCLUSION: The cognitive and upper extremity functions were correlated with the activities of daily living in stroke patients. Accordingly, applying physical therapy with a focus on improving the cognitive function and training activities of daily living could assist in the functional recovery of stroke patients significantly.

• 생물정신의학
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• 제14권4호
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• pp.221-231
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• 2007

Recent researches have shown that important cellular-based autoprotective mechanisms are mediated by heat-shock proteins(HSPs), also called 'molecular chaperones'. HSPs as molecular chaperones are the primary cellular defense mechanism against damage to the proteome, initiating refolding of denatured proteins and regulating degradation after severe protein damage. HSPs also modulate multiple events within apoptotic pathways to help sustain cell survival following damaging stimuli. HSPs are induced by almost every type of stresses including physical and psychological stresses. Our nervous system in the brain are more vulnerable to stress and damage than any other tissues due to HSPs insufficiency. The normal function of HSPs is a key factor for endogenous stress adaptation of neural tissues. HSPs play an important role in the process of neurodevelopment, neurodegeneration, and neuroendocrine regulation. The altered function of HSPs would be associated with the development of several neuropsychiatric disorders. Therefore, an understanding of HSPs activities could help to improve autoprotective mechanism of our neural system. This paper will review the literature related to the significance of HSPs in neuropsychiatric field.

• 대한물리의학회지
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• 제13권4호
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• pp.59-65
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• 2018

PURPOSE: The purpose of the present study is to investigate the changes in the cognitive function of elderly dementia patients residing in a residential care facility, following six weeks of brain-computer interface (BCI)-based cognitive training and to determine whether BCI-based cognitive training effectively improves their cognitive functions. METHODS: Thirty subjects diagnosed with dementia were randomly assigned to either the experimental or control group. Pre- and post-test cognitive function assessments were conducted using the mini mental state examination-Korean (MMSE-K) and Korean-dementia rating scale (K-DRS). The experimental group received BCI-based cognitive training, which consisted of games such as flying a ball and exploding a bomb, while the control group participated in music listening activities and National Health Gymnastics. Both groups engaged in a total of 18 sessions (3 times per week for 6 weeks, for 40 minutes per session). RESULTS: After 6 weeks of intervention, the experimental group had significantly increased MMSE-K scores ($19.53{\pm}1.30$ to $22.20{\pm}1.15$; p<.0011) and total K-DRS scores ($87.20{\pm}4.16$ to $99.33{\pm}1.15$; p<.0011). In addition, the experimental group showed greater cognitive improvements than the control group. CONCLUSION: The results of this study suggest that BCI-based cognitive training is a positive intervention tool for improving the cognitive function of dementia patients.

• 대한정형도수물리치료학회지
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• 제30권1호
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• pp.29-42
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• 2024

Background: This study aimed to determine the effects of training on breathing re-education on pain and dysfunction levels, posture, quality of life (QoL), and pulmonary function in patients. Methods: This study included 34 patients with chronic neck pain and upper thoracic breathing pattern were included. The participants were assigned to either the routine physical therapy program (RPTP) (CG; n=17) or RPTP and breathing pattern re-education training (EG; n=17). The CG and EG groups performed RPTP for 40 minutes, and only the EG groups performed breathing re-education training for 10 minutes. Exercises were performed thrice weekly for both groups. Level of pain and dysfunction, posture, QoL and pulmonary function status were assessed before and after the intervention. Results: After four weeks of intervention, numeric pain rating scale (NPRS), Korean version of neck disability index, cranio-vertebral angle, cranial rotation angle, and 12-item short form health survey-physical and mental component summaries had significant differences before and after intervention in both groups (p<.01). However, only NPRS, forced vital capacity, forced expiratory volume in 1s, and maximum voluntary ventilation showed significant interactions between the two groups and measurement time (p<.01). Conclusion: Breathing re-education training and RPTP may be optimal for patients with chronic neck pain and may be more effective in improving neck pain and pulmonary function.

• 대한통합의학회지
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• 제11권2호
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• pp.23-35
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• 2023

Purpose : Lung cancer induces a decrease in physical activity and a deterioration of respiratory ability. Exercise is an effective treatment to reduce side effects of anti-cancer treatments, also influence the survival and successful rehabilitation in lung cancer patients. However, there is insufficient evidence to show which period is the most effective to apply exercise for lung cancer patients. Therefore, this study was conducted to evaluate the efficacy of exercise-based interventions before and after surgery. Methods : Clinical trials (CTs) and randomized controlled trials (RCTs) reported in PubMed database were investigated. The trials investigated in this study were published for 10 years before August 20, 2022. The risk of bias was judged according to the Cochrane guideline. The materials included in this meta-analysis were 6-minute walk test (6MWT), pulmonary function, and quality of life (QOL). Results : 1 CT and 9 RCTs were selected in current study. In the meta-analysis, exercise increased 6MWT in preoperation (mean difference [MD] 29.49; 95 % confidence interval [CI] .99 to 57.99; p=.04; I²=0 %), 3 months postoperation (MD 54.97; 95 % CI 31.85 to 78.09; p<.001; I²=45 %) and 6 months postoperation (MD 85.59; 95 % CI 45.06 to 126.12; p<.001; I²=47 %). Exercise, also enhanced the lung function such as FEV₁/FVC (%) in postoperation (MD 7.64; 95 % CI 6.26 to 9.02; p<.001; I²=19 %). Additionally, exercise improved QOL, such as preoperative EORTC-QLQ-C30-LC13 in mental function (MD 3.21; 95 % CI .64 to 5.79; p=.01; I²=0 %) and postoperative SF-36 in mental component summary (MD 9.24; 95 % CI 4.94 to 13.54; p<.001; I²=0%). Conclusion : These results indicate that exercise-based intervention can elevate the ability to exercise and the mental componentof QOL within 3 months.

• 셀메드
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• 제7권3호
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• pp.12.1-12.6
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• 2017

The purpose of this study was to analyze the effect wool in patients with chronic obstructive pulmonary disease. The study was conducted experimentally on 53 patients with chronic obstructive pulmonary disease attending the chest diseases polyclinic of a hospital located in Erzurum. A randomized selection method was used to categorize patients into two groups; a treatment (n = 27), and a control group (n = 26). Patients in the treatment group (pre-test measurements were taken) wore wool vests for a period of three months, while patients in the control group wore cotton vests (placebo) for the same duration; post-test measurements were taken for both groups at the end of the three-month period. The Medical Outcomes Study Short Form 36, the St. George's Respiratory Questionnaire, and pulmonary function tests were used to collect data. Results concluded that there was a significant decrease (p < 0.05) in the overall score of the St. George's Respiratory Questionnaire, and the symptom, effect, and activity mean scores, while there was a significant increase (p < 0.05) in the SF-36 physical functioning, general health, bodily pain, role physical, vitality, role emotional, social functioning, mental health, physical and mental component summary mean scores of patients in the treatment group. Results of the study concluded that the symptoms, activity, disease effectiveness, and quality of life improved in patients that wore wool vests.

• 디자인학연구
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• 제15권4호
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• pp.139-148
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• 2002

본 연구에서는 조형(Form-Giving)이 가지는 언어적 능력 또는 기능으로써 'Fun' 감성의 발생과 수용을 다루고 있다. 조형언어로써 'Fun' 감성은 넓은 의미로 사용자가 인공물과의 관계를 통한 경험으로서 소유의지(가지고 싶은)를 갖게 하는 감성으로 정의한다. 좁은 의미로는 보다 능동적이고 의식적인 인지과정에서 겪게 되는 예상치 못한 조형 정보에 대한 물리적.심적 체험의 결과로써 소유의지가 생기는 경우의 감성을 'Fun' 감성으로 본다. 'Fun' 감성의 발생은 사용자의 인지적 특성으로부터 심적 정체(mental block)의 인지과정(여기서는 사용과정으로 보고 있음)을 통한 심적 정체의 해소 시점에서 발생됨을 유추할 수 있었다. 조형요소의 변형 및 규칙, 그리고 적용 조건을 인지적 관점에서 사용자 경험과 조형 컨텍스트(context)의 상호작용으로부터 제안하였다. 이는 목적하는 감성에 부합하는 조형(form-giving)에 있어 매우 중요한 요소로 다루어진다. 또한 다루고 있는 심적 정체로부터 'Fun' 감성 지향을 위한 조형 요소의 활용을 논하였다. 따라서 본 연구 내용을 기반으로 향후, 보다 실증적 연구를 통해, 디자인에 있어서 'Fun' 감성의 발생 메커니즘의 활용이 보다 매력적이고 흥미있는 제품 컨셉과 제품 형태에 효과적으로 적용되길 기대한다.

• 국제물리치료학회지
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• 제5권2호
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• pp.714-717
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• 2014

The goal of this study was to assess the effect of a group exercise program on cognitive function of elderly people. Subjects were chosen to be elders with dementia having minor to moderate degrees of cognitive function. Study was started out by randomly dividing the 16 subjects into two groups, each with 8 people; the group exercise group and the control group. The group exercise group performed 8 weeks of group exercise program and general physiotherapy while the control group only performed general physiotherapy. Cognitive function was measured by Korean version mini-mental state examination. The study group's attention and calculation statistically significantly improved but the control group saw no statistically significant change. The group exercise program affected improvement in cognitive function of elderly people with dementia and in particular, was effective for enhancing their attention and calculation.

• Physical Therapy Rehabilitation Science
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• 제11권1호
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• pp.32-42
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• 2022

Objective: This study was conducted to verify the effectiveness of a cognitive rehabilitation program consisting of physical exercises and mental activities for patients with chronic stroke with mild cognitive impairment (MCI). We aimed to investigate how this cognitive rehabilitation program affects patients' cognitive ability, depression, and sleep quality. Design: One group pretest-posttest design Methods: The study was conductedon 12 patients who participated in thecognitive rehabilitation complex exercise program for 16 weeks. The Korean version of the Montreal Cognitive Assessment (MoCA-K), Hamilton Depression Rating Scale (K-HDRS), and Pittsburgh Sleep Quality Index (PSQI) were used to evaluate the measured variables before and after study participation. The cognitive rehabilitation complex exercise program included 30 minutes of cognitive exercise and 30 minutes of Brill Exercise. The Wilcoxon signed-rank test was used to compare the variables before and after program participation. Cronbach's ɑ was used to assess the reliability of the test variables. Results: The post-program assessment showed a statistically significant increase in the MoCA-K score, which measures cognitive function (Z=-2.628, P=0.009). For depression ratings, there was a statistically significant decrease in the K-HDRS score (Z=-2.041, P=0.041). For sleep quality, although there was a numerical increase in the PSQI score, the difference was not statistically significant (Z=-0.702, P=0.483). The reliability test confirmed that all the individual test variables exhibited high reliability (cognitive function, 0.859; depression, 0.872; sleep, 0.822). Conclusions: We found that cognitive rehabilitation program used in this study had a positive effect on the cognitive function and depression in patients with chronic stroke with MCI.