• Title/Summary/Keyword: memorial project

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Implementation of Proteomics for Cancer Research: Past, Present, and Future

  • Karimi, Parisa;Shahrokni, Armin;Nezami Ranjbar, Mohammad R.
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.6
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    • pp.2433-2438
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    • 2014
  • Cancer is the leading cause of the death, accounts for about 13% of all annual deaths worldwide. Many different fields of science are collaborating together studying cancer to improve our knowledge of this lethal disease, and find better solutions for diagnosis and treatment. Proteomics is one of the most recent and rapidly growing areas in molecular biology that helps understanding cancer from an omics data analysis point of view. The human proteome project was officially initiated in 2008. Proteomics enables the scientists to interrogate a variety of biospecimens for their protein contents and measure the concentrations of these proteins. Current necessary equipment and technologies for cancer proteomics are mass spectrometry, protein microarrays, nanotechnology and bioinformatics. In this paper, we provide a brief review on proteomics and its application in cancer research. After a brief introduction including its definition, we summarize the history of major previous work conducted by researchers, followed by an overview on the role of proteomics in cancer studies. We also provide a list of different utilities in cancer proteomics and investigate their advantages and shortcomings from theoretical and practical angles. Finally, we explore some of the main challenges and conclude the paper with future directions in this field.

A Basic Study on the Architectural Characteristics of Seokgojeon (석고전(石鼓殿)의 건축적 특성에 관한 기초 연구)

  • Son, Chang-Il;Lee, Seung-Yong
    • Journal of the Korean Institute of Rural Architecture
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    • v.25 no.2
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    • pp.17-24
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    • 2023
  • Seokgojeon(石鼓殿) is a protective pavilion that protects stone drums made in 1902 during the Korean Empire in connection with Emperor Gojong's Mangyuksun (51'st birthday) and the commemoration of the 40th anniversary of his reign. During the Japanese colonial period, Seokgojeon was dismantled and transformed into the bell pavilion of Bakmunsa Temple, which was a memorial temple for Ito Hirobumi in 1935. In November 1945, just after liberation, Bakmunsa Temple was burned down, and the Seokgojeon Hall, which was transformed into Jonggak(鐘閣), was relocated to the Changgyeongwon(昌慶苑). Outdoor Stage in 1966, and was dismantled in 1984 due to the Changgyeonggung(昌慶宮) Palace restoration project, and only the members are currently stored. Therefore, this paper intends to use it as a basic research data to examine the style of monumental buildings during the Korean Empire through literature surveys, absence surveys, and case studies of similar buildings during the same period.

Using Implementation Science to Advance Cancer Prevention in India

  • Krishnan, Suneeta;Sivaram, Sudha;Anderson, Benjamin O.;Basu, Partha;Belinson, Jerome L;Bhatla, Neerja;D' Cruz, Anil;Dhillon, Preet K.;Gupta, Prakash C.;Joshi, Niranjan;Jhulka, PK;Kailash, Uma;Kapambwe, Sharon;Katoch, Vishwa Mohan;Kaur, Prabhdeep;Kaur, Tanvir;Mathur, Prashant;Prakash, Anshu;Sankaranarayanan, R;Selvam, Jerard M;Seth, Tulika;Shah, Keerti V;Shastri, Surendra;Siddiqi, Maqsood;Srivastava, Anurag;Trimble, Edward;Rajaraman, Preetha;Mehrotra, Ravi
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.9
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    • pp.3639-3644
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    • 2015
  • Oral, cervical and breast cancers, which are either preventable and/or amenable to early detection and treatment, are the leading causes of cancer-related morbidity and mortality in India. In this paper, we describe implementation science research priorities to catalyze the prevention and control of these cancers in India. Research priorities were organized using a framework based on the implementation science literature and the World Health Organization's definition of health systems. They addressed both community-level as well as health systems-level issues. Community-level or "pull" priorities included the need to identify effective strategies to raise public awareness and understanding of cancer prevention, monitor knowledge levels, and address fear and stigma. Health systems-level or "push" and "infrastructure" priorities included dissemination of evidence-based practices, testing of point-of-care technologies for screening and diagnosis, identification of appropriate service delivery and financing models, and assessment of strategies to enhance the health workforce. Given the extent of available evidence, it is critical that cancer prevention and treatment efforts in India are accelerated. Implementation science research can generate critical insights and evidence to inform this acceleration.

Change of Seoul's Downtown Planning: Focusing on Urban Conservation from the 1960s to the 1990s (서울시 도심 계획 방식의 변화: 1960년대부터 1990년대의 도시보전을 중심으로)

  • Rhee, Bum-Hun
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.9
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    • pp.39-48
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    • 2020
  • The purpose of this study was to understand changes in Seoul's downtown planning from the 1960s to 1990s. The approach was examined by classifying its formation process though urban conservation. The effects of modernization and urbanization on Seoul's downtown planning were as follows. In the 1960s, Seoul attempted to decentralize urban functions due to excessive population. In the 1970s, a policy to diversify urban functions according to Gangnam development was enacted. In the 1980s, the existing downtown declined, and the sub-downtown grew with changing urban functions. In the 1990s, the identity of the existing downtown was recognized through the Seoul Memorial Project. This study also analyzed downtown planning efforts concerned with urban conservation. First, the physical aspects of existing buildings and street facilities were maintained. Second, the spatial aspects for the maintenance of surrounding areas were proposed. Fourth, the social aspects for accessibility by Seoul citizens was improved. This analysis demonstrates the concept of urban conservation based on physical-spatial-social aspects.

The Process of Place-making and the Placeness of the 'Kim Gwang-seok Road' in Daegu ('김광석 다시 그리기 길'의 장소 만들기와 장소성)

  • Park, Soon Ho
    • Journal of the Economic Geographical Society of Korea
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    • v.23 no.4
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    • pp.438-453
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    • 2020
  • This study attempts to examine the process of place-making, to define the role and interrelationship of the subjects and to analyze the placeness of the 'Kim Gwang-seok Road', a representative example of artificial place-making. Through a 10-year urban regeneration project based on the concept of Kim Gwang-seok, the alleyway between Bangcheon Market and the retaining wall of Sincheon-daero has been embedded as a memorial space for Kim Gwang-seok and an cultural art space. However, the existing placeness has weakened as the result of the excessive tourism in the late 2010s, while the characteristics of cultural commercial space has strengthened. This change in place has prompted community disintegration, which has caused the loss of momentum for sustainable development. To overcome these problems, it will be necessary to establish endogenous governance to expand and reproduce existing community capabilities, embedded social capital and place assets in new directions.

A Study on the Place Identity of Tapgol Park - Focused on the Phenomena after Sacralization Project - (탑골공원의 장소 정체성에 대한 연구 - 성역화사업 이후 현상을 중심으로 -)

  • Han, Sung-Mi
    • Journal of the Korean Institute of Landscape Architecture
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    • v.44 no.3
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    • pp.25-36
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    • 2016
  • As the first public park in Korea, birth place of the march first independence movement, and a representative space of leisure of old men, Tapgol Park contains diverse symbolisms and meanings. In 2000, Seoul authorities selected the symbolism of the March First independence movement, and carried forward the sacralization project of Tapgol Park. They eliminated facilities, including vending machines, and restricted most of the leisure activities in the park such as drinking singing dancing, speech, playing chess, writing calligraphy, etc., and loitering. Also, they changed the park's design into a less available space with green areas and switched wooden benches to granite stone. Since the project finished, a representative phenomenon was the elderly men's exodus to Jongmyo Park, where the restrictions were not strong as in Tapgol Park. As a result, the numbers of users in Tapgol Park decreased sharply. However, overcrowded(more than 3000) Jongmyo Park is also in the middle of a sacralization project now. According to an investigation including observation and in-depth interview, most of the elderly men who use the parks almost everyday were in the low economic class. They just visit the parks everyday and chat with their peers, gaining comfort from each other. These phenomena can be interpreted as a social exclusion in society, which made the elderly men move to another place. Meanwhile, although fifteen years has passed since the project was completed, many people still regard the Tapgol Park as a place for elderly men instead of the birth place of the March First Independence Movement. This study focused on such problems and vague place identity, which is neither a memorial place nor a public park. The study discovery the fact they missed the symbolism that Tapgol Park was the first urban park of Korea. Also, it stresses that the monumentality does not need to be sacred, reverent, or inflexible. With this point of view, this study discussed public aspect and everydayness, which are included in most of the urban parks. Finally, this study suggests Tapgol Park as an urban park that has an identity that embraces the condition of monumentality, everydayness, and publicness all together.

A Reconsideration on the Records on Doju Cho Jeongsan and His Family in Manchuria, China (조정산 도주 일가의 만주행록에 관한 재고찰)

  • Cui, Fenglong
    • Journal of the Daesoon Academy of Sciences
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    • v.26
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    • pp.215-253
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    • 2016
  • In 2007, according to the records, I made an on-the-spot survey of the place where Doju Cho Jeongsan and his family might have lived in exile in Manchuria and released a paper in which I decided that the site could be the Shuidongchun (village) of Luotongshanzhen in Liuhexian, Jilin Province. Thereafter, sponsored by the Doju Cho Jeongsan's Memorial Project from 2008 to 2013, many times, I carried out the field investigations and researches on Liuhexian, including the visits of the institutions which have the historical documents, in order to find the data related to the participation of him and his family in the anti-Japanese movement. I was, hence, able to reconfirm that the village had been the place of their exile, based on my collected data and the oral reports which the local historians and ethnic Korean elders had provided. In this study, using the historical documents and maps and the oral materials, I made an attempt to prove the historical truth thoroughly once again. First, the existing sources of Doju Cho and his family's settling in Manchuria from March 1909 to 1917, were carefully analyzed which were described in The Jin-gyeong. In doing so, the misspelling of the names and the spatio-temporal errors of the people's activities were corrected. Next, I researched on another town, Shuitungou of Liuhexian in Fengtian Province (in West Gando of Manchuria), which it is known that Doju and his family stayed in, and the Laogushan (mountain), which it is believed that Doju cultivated himself in. Finally, through the attempt, I reached the conclusion that Doju and his family had settled at Shuidongchun (once called Shuidonggou or Shuitongchun) of Luotongshanzhen (once called Datonggou) in Liuhexian, Jilin Province. In the Liuhexian-related documents and maps published in the eras of Republican China and Manchuria, the place name called Shuitungou was not found. However, I discovered a map in the era of Republican China on which Shuitongchun was recorded as Shuidonggou. In addition, considering the administration system of Republic China, tun(屯) and gou(溝) could not be used together in the place names. Accordingly, Shuitungou was more likely misspelled as Korean people in those days mispronounced Shuidonggou. Furthermore, people in China has habitually called the Dagushan(大孤山), located in the north of Gushanzizhen of Liuhexian, as the Laogushan(老孤山). This means that the Korean people who lived in the area then perhaps recorded the mountain as the Nogosan(老姑山), the mountain of the old goddess, according to Korean enunciation, because they had the custom of worshipping the mountain goddess. I tried my best to find the historical documents regarding Doju and his family's anti-Japanese activities to prove the location of exile in which they settled in northeastern China (Manchuria). However, I was not able to reach the initial goal completely due to the shortage of objective evidences, only to leave tasks to be solved. I hope that this study can give a little help to researchers who are interested in this matter.

Management and Use of Oral History Archives on Forced Mobilization -Centering on oral history archives collected by the Truth Commission on Forced Mobilization under the Japanese Imperialism Republic of Korea- (강제동원 구술자료의 관리와 활용 -일제강점하강제동원피해진상규명위원회 소장 구술자료를 중심으로-)

  • Kwon, Mi-Hyun
    • The Korean Journal of Archival Studies
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    • no.16
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    • pp.303-339
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    • 2007
  • "The damage incurred from forced mobilization under the Japanese Imperialism" means the life, physical, and property damage suffered by those who were forced to lead a life as soldiers, civilians attached to the military, laborers, and comfort women forcibly mobilized by the Japanese Imperialists during the period between the Manchurian Incident and the Pacific War. Up to the present time, every effort to restore the history on such a compulsory mobilization-borne damage has been made by the damaged parties, bereaved families, civil organizations, and academic circles concerned; as a result, on March 5, 2004, Disclosure act of Forced Mobilization under the Japanese Imperialism[part of it was partially revised on May 17, 2007]was officially established and proclaimed. On the basis of this law, the Truth Commission on Forced Mobilization under the Japanese Imperialism Republic of Korea[Compulsory Mobilization Commission hence after] was launched under the jurisdiction of the Prime Minister on November 10, 2004. Since February 1, 2005, this organ has begun its work with the aim of looking into the real aspects of damage incurred from compulsory mobilization under the Japanese Imperialism, by which making the historical truth open to the world. The major business of this organ is to receive the damage report and investigation of the reported damage[examination of the alleged victims and bereaved families, and decision-making], receipt of the application for the fact-finding & fact finding; fact finding and matters impossible to make judgment; correction of a family register subsequent to the damage judgement; collection & analysis of data concerning compulsory mobilization at home and from abroad and writing up of a report; exhumation of the remains, remains saving, their repatriation, and building project for historical records hall and museum & memorial place, etc. The Truth Commission on Compulsory Mobilization has dug out and collected a variety of records to meet the examination of the damage and fact finding business. As is often the case with other history of damage, the records which had already been made open to the public or have been newly dug out usually have their limits to ascertaining of the diverse historical context involved in compulsory mobilization in their quantity or quality. Of course, there may happen a case where the interested parties' story can fill the vacancy of records or has its foundational value more than its related record itself. The Truth Commission on Compulsory mobilization generated a variety of oral history records through oral interviews with the alleged damage-suffered survivors and puts those data to use for examination business, attempting to make use of those data for public use while managing those on a systematic method. The Truth Commission on compulsory mobilization-possessed oral history archives were generated based on a drastic planning from the beginning of their generation, and induced digital medium-based production of those data while bearing the conveniences of their management and usage in mind from the stage of production. In addition, in order to surpass the limits of the oral history archives produced in the process of the investigating process, this organ conducted several special training sessions for the interviewees and let the interviewees leave their real context in time of their oral testimony in an interview journal. The Truth Commission on compulsory mobilization isn't equipped with an extra records management system for the management of the collected archives. The digital archives are generated through the management system of the real aspects of damage and electronic approval system, and they plays a role in registering and searching the produced, collected, and contributed records. The oral history archives are registered at the digital archive and preserved together with real records. The collected oral history archives are technically classified at the same time of their registration and given a proper number for registration, classification, and keeping. The Truth Commission on compulsory mobilization has continued its publication of oral history archives collection for the positive use of them and is also planning on producing an image-based matters. The oral history archives collected by this organ are produced, managed and used in as positive a way as possible surpassing the limits produced in the process of investigation business and budgetary deficits as well as the absence of records management system, etc. as the form of time-limit structure. The accumulated oral history archives, if a historical records hall and museum should be built as regulated in Disclosure act of forced mobilization, would be more systematically managed and used for the public users.