• Title/Summary/Keyword: membrane topology

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Design of the Non-Isolated Fuel Cell Boost Charger for the Lithium Polymer Battery with Low Output Ripple (낮은 출력 리플을 갖는 연료전지를 이용한 리튬폴리머 전지용 비절연형 승압 충전기의 설계)

  • Tran, Van Long;Choi, Woojin
    • Proceedings of the KIPE Conference
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    • 2013.07a
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    • pp.182-183
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    • 2013
  • In the design of the fuel cell charger, it is important to find out the suitable topology and to design the converter to guarantee the performance of the fuel cell as well as the battery. Most of the chargers developed so far have used step-down converters. However, since the small fuel cell stack can only generate a low voltage, it is required to use the step-up converter to charge the battery. In this paper, a modified non-isolated boost charger topology for the Proton Exchange Membrane Fuel Cell (PEMFC) is proposed to meet the strict ripple requirements for the battery charge and its control method by using PI controller is detailed. The feasibility of the proposed topology and its control method is then verified by the experiments.

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Membrane Topology of Helix 0 of the Epsin N-terminal Homology Domain

  • Kweon, Dae-Hyuk;Shin, Yeon-Kyun;Shin, Jae Yoon;Lee, Jong-Hwa;Lee, Jung-Bok;Seo, Jin-Ho;Kim, Yong Sung
    • Molecules and Cells
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    • v.21 no.3
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    • pp.428-435
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    • 2006
  • Specific interaction of the epsin N-terminal homology(ENTH) domain with the plasma membrane appears to bridge other related proteins to the specific regions of the membrane that are invaginated to form endocytic vesicles. An additional $\alpha$-helix, referred to as helix 0 (H0), is formed in the presence of the soluble ligand inositol-1,4,5-trisphosphate [$Ins(1,4,5)P_3$] at the N terminus of the ENTH domain (amino acid residues 3-15). The ENTH domain alone and full-length epsin cause tubulation of liposomes made of brain lipids. Thus, it is believed that H0 is membrane-inserted when it is coordinated with the phospholipid phosphatidylinositol-4,5-bisphosphate [$PtdIns(4,5)P_2$], resulting in membrane deformation as well as recruitment of accessory factors to the membrane. However, formation of H0 in a real biological membrane has not been demonstrated. In the present study, the membrane structure of H0 was determined by measurement of electron paramagnetic resonance (EPR) nitroxide accessibility. H0 was located at the phosphate head-group region of the membrane. Moreover, EPR line-shape analysis indicated that no pre-formed H0-like structure were present on normal acidic membranes. $PtdIns(4,5)P_2$ was necessary and sufficient for interaction of the H0 region with the membrane. H0 was stable only in the membrane. In conclusion, the H0 region of the ENTH domain has an intrinsic ability to form H0 in a $PtdIns(4,5)P_2$-containing membrane, perhaps functioning as a sensor of membrane patches enriched with $PtdIns(4,5)P_2$ that will initiate curvature to form endocytic vesicles.

TM4SF5-mediated protein-protein networks and tumorigenic roles

  • Lee, Jung Weon
    • BMB Reports
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    • v.47 no.9
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    • pp.483-487
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    • 2014
  • Transmembrane 4 L six family member 5 (TM4SF5), as a membrane glycoprotein with 4 transmembrane domains, is similar to the tetraspanins in terms of membrane topology and plays important roles in tumorigenesis and tumor metastasis. Especially, TM4SF5 appears to form a massive protein-protein complex consisting of diverse membrane proteins and/or receptors in addition to cytosolic signaling molecules to regulate their signaling activities during the pathological processes. TM4SF5 is shown to interact with integrins ${\alpha}2$, ${\alpha}5$, and ${\beta}1$, EGFR, IL6R, CD151, focal adhesion kinase (FAK), and c-Src. This review focuses on the significance of the interactions with regards to TM4SF5-positive tumorigenesis and metastasis.

Topology Optimization for End Plate of Fuel Cell Stack (연료전지스택 바깥판의 위상최적설계)

  • Choi, Woo-Seok;Oh, Sung-Jin;Kim, Sung-Jong;Hong, Byung-Sun
    • Proceedings of the KSME Conference
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    • 2003.04a
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    • pp.456-461
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    • 2003
  • A fuel cell is an electrochemical device in which the energy of a chemical reaction is converted directly into electricity. By combining hydrogen fuel with oxygen from air, electricity is formed, without combustion of any form. Water and heat are the only by-products when hydrogen is used as the fuel source. Fuel cell stack consists of multi-layered unit cells. A unit cell consists of MEA and bipolar plates. The end plate of fuel cell stack should give a uniform distributed pressure to multi unit cell layers so as to reduce the contact resistance and to prevent the leakage of reactant gases and the damage of multi layer components. The current end plate is redundantly large and heavy. It makes the power per unit volume reduced. Topology optimization of end plate is conducted for mass reduction and enhancement of bending rigidity. The evaluation of the current design and the recommendation for the future design is remarked.

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Analysis of Stabilizing Process for the Unstable Truss Structures using a Topology of Member Connection (구성부재의 위상을 이용한 불안정 트러스 구조물의 안정화 이행과정)

  • 권택진;김진우;김재열
    • Proceedings of the Computational Structural Engineering Institute Conference
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    • 2001.04a
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    • pp.251-258
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    • 2001
  • Cable and membrane structures can be classified as a unstable structure in the view point of shape determination process. An unstable stucture at the initial state generally cannot take a role as the resistance for the external force. Therefore, there should be a stabilizing process to get the stable state of a structure and it is necessary to visualize the shape finding from unstable state to stable state. In this paper, a numerical method of stabilizing procedure for the link structures is presented. The structures are assumed to have rigid movements and thus only changing of the topology of member is considered during the analysis. The generalized inverse matrix and the principle of minimum potential energy are used in the process. Illustrative examples are presented and the results show good convergence.

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A Study on the Characteristics of Topological Invariant Expression in the Space of Digital Architecture (디지털건축공간에 나타난 위상기하학적 불변항의 표현특성에 관한 연구)

  • Bae Kang-Won;Park Chan-Il
    • Korean Institute of Interior Design Journal
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    • v.14 no.3 s.50
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    • pp.64-72
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    • 2005
  • The purpose of this study is to propose a topological design principles and to analyze the space of digital architecture applying topological invariant expressive characteristics. As this study is based on topology as a science of true world's pattern, we intented to explain the concepts and provide some methods of low-level and hyperspace topological invariant Properties. Four major aspects are discussed. Those are connection theory, boundary concept, homotopy group, knot Pattern theory as topological invariant properties. Then we intented to make understand topological characteristics of the Algorithms, luring machine, cellular automata, string theory, membrane, DNA and supramolecular chemistry. In fine, the topological invariant properties of the digital architecture as genetic algorithms based on self-organization and heterogeneous networks of interacting actors can be analyzed and used as a critical tool. Therefore topology can be provided endless possibilities for architecture, designers and scientists intended in expressing the more complex and organic patterns of nature as life.

Crease Behavior of Thin Membrane (멤브레인의 접힘 거동 연구)

  • Woo, Kyeong-Sik
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.35 no.10
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    • pp.905-911
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    • 2007
  • In this paper, geometrically and materially non-linear finite element analyses were performed to study the crease behavior of thin membranes. The cross-section of the membrane was modeled with 2-dimensional plane strain elements. To simulate the creasing process, the membrane mesh was folded, compressed to prescribed crease gauge by activating two rigid contact surfaces, and then released to give the crease topology. Various crease gauges were considered to investigate the effect of crease intensity on the initial deployment angle. The crease geometry was also obtained by experiments and the results were compared.

Development of an Open-Typed Optimal Trolley Model for Cable-Based Retractable Membrane Roof (케이블 기반 개폐 막 지붕의 오픈형 최적 트롤리 모델 개발)

  • Lee, Donwoo;Shon, Sudeok;Choi, Bongyoung;Lee, Seungjae
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.22 no.1
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    • pp.719-727
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    • 2021
  • In the field of architecture, retractable devices capable of responding flexibly to the environment have been applied widely to large structures. Among these devices, the aesthetically pleasing retractable membrane is lightweight so that the membrane can be opened easily using only a traction device. On the other hand, because the towed membrane moves as it is connected to the main cable by a trolley, the number of trolleys needed increases in proportion to the roof's area. This study proposes an optimal model for an open-type trolley (OTT), which is used widely in these devices, using topology optimization. The analysis used the ANSYS program. A new model was proposed based on the results and reviewed through the feedback. Through this process, it was possible to develop a prototype with increased durability and reduced weight. For OTT, optimization was performed based on static analysis and the boundary conditions, so three prototypes were designed. A comparison of the proposed trolley with the conventional one under the same conditions revealed an up to 71.04% decrease in volume while the yield-strength reached 8.67 to 11.43%. In conclusion, the optimal trolley proposed was found to be reliable in terms of economy and stability.

A Study on the Distribution of Cytochrome-c-oxidase Subunit in the Cristae of Mitochondria (미토콘드리아 크리스테에 존재하는 cytochrome-c-oxidase의 단백질 소단위 분포에 관한 연구)

  • Kim, Soo-Jin;Lee, Ji-Hyon;Chung, Cha-Kwon
    • Applied Microscopy
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    • v.24 no.4
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    • pp.41-51
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    • 1994
  • The topology of the enzyme has been investigated by biochemical studies including chemical labeling and cross linking. Thirteen subunits(polypeptides) of the cytochrome-c-oxidase have localistic characteristics of existing in the matrix side or cytoplasmic side in the mitochondria. In order to observe the distribution of the enzyme subunit on the mitochondria membrane, immunogold-labeling methods were employed. Antibody was obtained from the serum of immunized rabbit with enzyme subunit antigen which was obtained from cytochrome-c-oxidase of the beef heart muscle mitochondria. Beef heart muscle tissue as a tissue antigen was stained with immunized rabbit IgG and protein A gold complex. Electron microscopy has identified the existance of cytochrome-c-oxidase subunit $Mt_I,\;Mt_{II}\;and\;Mt_{III}$ on the membrane of cristae and outer chamber of mitochondria and the subunit $C_{IV}$ on the membrane of cristae and matrix of mitochondria. Particularly, the subunit $C_{IV}$ was also observed to exist in the sarcoplasm of muscle tissue.

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Fabrication of Nonconductive Microscale Patterns on Ion Exchange Membrane by Laser Process (레이저 가공을 이용한 이온교환막 표면의 비전도성 마이크로 패턴의 제작)

  • Jinwoong Choi;Myeonghyeon Cho; Bumjoo Kim
    • Korean Journal of Materials Research
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    • v.33 no.2
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    • pp.71-76
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    • 2023
  • The electroconvection generated on the surface of an ion exchange membrane (IEM) is closely related to the electrical/chemical characteristics or topology of the IEM. In particular, when non-conductive regions are mixed on the surface of the IEM, it can have a great influence on the transfer of ions and the formation of nonlinear electroconvective vortices, so more theoretical and experimental studies are necessary. Here, we present a novel method for creating microscale non-conductive patterns on the IEM surface by laser ablation, and successfully visualize microscale vortices on the surface modified IEM. Microscale (~300 ㎛) patterns were fabricated by applying UV nanosecond laser processing to the non-conductive film, and were transferred to the surface of the IEM. In addition, UV nanosecond laser process parameters were investigated for obvious micro-pattern production, and operating conditions were optimized, such as minimizing the heat-affected zone. Through this study, we found that non-conductive patterns on the IEM surface could affect the generation and growth of electroconvective vortices. The experimental results provided in our study are expected to be a good reference for research related to the surface modification of IEMs, and are expected to be helpful for new engineering applications of electroconvective vortices using a non-conductive patterned IEM.