• 생약학회지
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• 제34권4호통권135호
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• pp.335-338
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• 2003

It is thought that highly reactive oxygen species generated after strokes plays a key role in damaging the brain. We examined free radical scavenging activity and neuroprotective effects of several medicinal herbs in a rat model of transient ischemia. Free radical scavenging property of medicinal herbs was examined in vitro using 1,1-diphenyl-2-picrylhydrazyl stable free radical. Transient ischemia was induced by intraluminal occlusion of the right middle cerebral artery for 120 min, followed by reperfusion for 22 hr in rats. Aqueous extracts of 8 medicinal herbs (200 mg/kg) were orally administered twice to transient ischemic rat prior to reperfusion and 2 hr after reperfusion. Total infarction volume in the hemisphere ipsilateral to the ischemia-reperfusion was significantly decreased in 7 groups treated with Sophora flavescens, Lycopus lucidus, Sanguisorba officinalis, Caesalpinia sappan, Albizia julibrissin, Rubia akane, Psoralea corylifolia, or Prunella vulgaris. However, neuroprotective effects of these medicinal herbs were not correlated with their antioxidative activities. These results suggest that these medicinal herbs exert neuroprotection via antioxidative as well as unknown mechanism.

• 한국식품영양과학회지
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• 제34권1호
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• pp.113-119
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• 2005

한국의 전통적인 식육가공품인 양념 불고기에 한약재 물 추출물을 첨가함으로서 얻어지는 저장성 및 품질 증진효과를 살펴본 결과, pH는 4$^{\circ}C$에서 저장 9일 이후에도 변화가 거의 없이 안정하게 유지되었다. 수분함량은 전반적으로 감소하는 경향을 보였지만 한약재 물 추출물을 2% 첨가한 구에서는 가장 안정하게 유지되었다. 양념 우육의 전단력은 저장기간 동안 점점 낮아졌는데, 한약재 물 추출물 처리구가 무 처리구보다 전단력이 낮게 나타나 식육의 연화효과가 있음을 보여 주고 있다. 양념우육의 색은 적색도에 있어 한약재 2% 처리구에서 저장 기간 중 큰 변화가 없이 가장 안정하게 유지되었다. TBA값은 저장 9일 이후에 한약재 물 추출물을 첨가한 구에서 매우 낮게 나타났고 증가 비율도 낮았다. 양념 우육의 생균수 변화는 무 처리구에서 가장 빠르게 증가해, 한약재 물 추출물을 첨가한 경우 저장 6일까지 $10^{5}$ CFU/g으로 안정하게 유지되어 가식기간을 연장시켜 주었다. 관능평가에서 양념우육의 색, 외관, 연도, 탄성, 다즙성, 향, 맛은 전반적으로 한약재 물 추출물 처리구에서 무 처리구보다 더 높은 값을 얻었으며, 양념우육의 저장성과 연도에 있어서 한약재 물 추출을 0.5%에서 1% 첨가했을 때 관능적 특성과 색 등에 관하여 가장 바람직한 결과를 기대할 수 있음을 알 수 있었다. 이상의 결과를 종합해 보면, 양념우육에 한약재 물 추출물을 0.5%에서 1% 정도 첨가하는 것이 저장성의 증진 및 연도의 개선, 관능적 특징의 개선 등으로 양념우육의 품질을 향상시키는데 적합한 방법이라 사료된다.

• 한국자원식물학회지
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• 제6권1호
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• pp.33-44
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• 1993

The medicinal plants used traditional medicines are classified into two groups. The first group is formulary medicine which have been recorded on authorized books, for example, kampo drug in Japan. The second group is the fork medicines. These medicinal plants production is 165 billion yen(about 1.5 billion dollar) and which rate to to total pharmaceutical production is about 3% in 1990. The number of important medicinal plants treated in the market is 124 herbs from the total 364 herbs for kampo durgs(210 preparations kampo durgs) and other propritetary drugs (agents for common cold, laxatives, gastrointestional and so on). The production of the Ginseng and Bupleurum Root are increased about ten times in last twelve years(1976 or 1988). The 80% of these medicinal plants are imported from China, Korea and Southern Asian countries. Then the Pharmaceutical Affairs Bureau of Ministry of Health and Welfare published "The Guideline of Medicinal Plant for Cultivation" for a quality control and a stabilization supply of 80 herbs. The first part(1992) of the guideline reported 5 herbs; Coptis Rhizome, Rehmannia Root, Bupleur, Root, Japanese Angelica Root and Rhubarb, The next part will be published following 5herbs; Cnidium Rhizome, Safflower, Coix seed and Fruiet, Platicodon Root and Zedoary.

• 한국약용작물학회:학술대회논문집
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• 한국약용작물학회 2008년도 춘계학술발표회
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• pp.89-90
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• 2008

• 한국약용작물학회지
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• 제15권3호
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• pp.189-193
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• 2007

사철쑥 (Artemisia capillaris Thunb.)의 수확시기 및 부위별 생육특성, scoparone과 capillarisin함량을 조사하여 약리 성분 함량이 높은 수확시기와 부위를 알아본 결과는 다음과 같다. 사철쑥은 7월 30일경 꽃봉오리가 형성되었으며 8월 30일 만개하여 9월에 종자가 성숙되었다. 생육은 8월 30일에 가장 양호하여 생체중과 건물중이 높았다. 특히 이 시기에 엽은 관찰되지 않았고 생체중은 243.7g으로 높았는데 종실의 무게는 109.6g, 줄기의 무게는 134.Is이었다. Scoparone 함량은 종실에 많이 함유되어 있었는데 8월 30일 종실에서 6.50mg/g DW로 가장 높았다. 또한 capillarisin은 줄기에는 존재하지 않았으며 엽과 종실에서 나타났는데 7월 30일 종실에 1.65mg/g DW로 가장 많이 함유되어 있었다.

• 동아시아식생활학회지
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• 제19권6호
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• pp.882-890
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• 2009

In this study, dietitians working in the school foodservice industry in the Chungbuk region were surveyed to determine their perception of medicinal herbs and medicinal foods in order to obtain basic data for developing medicinal food menus. The findings of this study are as follows. Many of the dietitians had low confidence in medicinal herbs used in medicinal foods. However the more the subjects ate such food, the higher their perception was. The higher the perception and reliability were, the more positive the answer was in terms of taste, nutrition and efficacy. Regarding the familiarity with medicinal herbs, the subjects, regardless of their age, showed a high perception of easily accessible medicinal herbs; younger subjects preferred Schisandrae fructus, Rubi fructus and Acanthopanacis cortex. The higher the perception and the eating frequency were, the higher the familiarity was. Regarding the development of medicinal food menus, the older the subjects were, the more positive they viewed the development of menus. Also, dietitians with 15 years of experience showed a high interest in the development of new menus.

• 화훼연구
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• 제16권2호
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• pp.93-101
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• 2008

식물재료로는 꽃차로 이용되고 있는 식물 중 한의학 서적에 약효가 기록되어 있는 55종을 대상으로 하였다. 이들 식물의 한의학적인 약효를 해표약, 이수약, 청열약, 사하약, 보익약, 보기약, 보혈약, 온리약, 이기약, 방향화습약과 활혈약 등 11군으로 분류하였다. 또한 이 식물들은 열(열, 온, 미온, 평, 량, 한), 맛(달다, 쓰다, 맵다, 시다, 짜다), 독성(있다, 없다) 별로 분류되었다. 꽃차의 음용은 일반적으로 모든 사람에게 이용가능할 것으로 알려져 있다. 그러나 꽃차를 음용 할 때는 본인의 체질과 건강상태에 맞는 꽃차를 선택하는 것이 중요하다. 독성이 있는 식물을 꽃차로 음용 할 때는 주의를 기울여야하고 몸이 허약한 사람은 음용을 금해야 한다. 앞으로 좀 더 많은 임상적인 연구가 진행된다면 꽃차의 건강학적 효능에 따른 상품화가 가능할 것으로 판단된다.

• 동아시아식생활학회지
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• 제13권3호
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• pp.176-184
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• 2003

This experiment was planned to develop a functional supplements by food resources to prevent and lessen the bad effects caused by the environmental pollution such as bad food, air, water and heavy metals exposed to people these days. As for Its primary stage, the nutrient profile and sensory characteristics of the duck-extract were evaluated in this study. The duck-extract was formulated by the mixture of bone and internal organs of ducks and 6 medicinal herbs which were able to be used as foods and known to help the excretion and the repression of the poison inside the body for a long time. As we compared the six medicinal herbs mentioned above to the vegetable herbs, the nutrient profile of the medicinal herbs were superior to the vegetable herbs. The duck-extract was composed of protein 49.92%, carbohydrate 37.02%, dietary fiber 20.99%, lipid 7.60% and ash 5.46%. The ratio of Ca to P was 1 : 1.4, which was a suitable ratio for absorption, the contents of Na and K were low and those of micro-elements such as Fe, Mn, Zn and Cu high compared to other meat extracts. The essential amino acids accounted for 30.91% of total amino acids. The result of sensory evaluation was better in overall preferences than the ones which are already in the market. From these results, the nutrient profile of the duck-extract was estimated to be able to supply enough nutrients to the people whose nutritional balance was destroyed these days. This study also showed the effective way of using duck-extract and its application to the oriental medicine.

• Preventive Nutrition and Food Science
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• 제19권3호
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• pp.178-186
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• 2014

Many recent studies have focused on maintaining a healthy life by preventing and/or postponing the aging process. Numerous studies have reported that continuous exposure to reactive oxygen species can stimulate skin aging and that excessive accumulation of fat can cause an impaired skin barrier and tissue structure alterations. Thus, the maintenance of antioxidant homeostasis and the suppression of adipose accumulation are important strategies for skin anti-aging. Here, we prepared three types of extracts [whole juice, acetone-perchloric acid (PCA), and ethanol] from 20 fruits and medicinal herbs native to the Gyeongnam area of Korea. The total phenolic content of each extract was analyzed, and we observed higher total phenolic contents in the medicinal herbs. Consistent with this, the results of the oxygen radical absorbance activity capacity assay indicated that the in vitro antioxidant activities of the medicinal herb extracts were stronger than those of the fruit extracts. The fruits and medicinal herbs had strong effects on cell-based systems, including $H_2O_2$-induced oxidative stress in human keratinocytes and 3T3-L1 lipid accumulation. Nishimura Wase persimmon, Taishu persimmon, wrinkled giant hyssop, sweet wormwood, Chinese cedar, red perilla, tan shen, hiyodori-jogo, and cramp bark may be natural anti-aging materials with effective antioxidant and anti-adipogenic activities. Taken together, our findings may provide scientific evidence supporting the development of functional foods and nutraceuticals from fruits and medicinal herbs.

• Food Science and Biotechnology
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• 제17권2호
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• pp.408-412
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• 2008

Determining the elution of water-soluble substances from herbal teas is an important factor in their efficient use in terms of taste, perfume, and content of health-related components. The antioxidant activity and content of catechins in commercial Chrysanthemum indicum (gamguk) teas were determined for optimum elution conditions. The water extract of gamguk teas did not differ significantly in yield compared to methanol extracts and showed stronger antioxidant activity. Catechin contents in gamguk teas were 8-18% of the extracts when individual peaks in high-performance liquid chromatography analysis were compared to standard catechin peaks. Gamguk teas exhibited faster release of antioxidants, and the antioxidant activity was positively correlated with the thermal treatments. Gukhwacha (GC) was the best tea for rapid release (30 sec) of antioxidants with the $50^{\circ}C$ treatment, whereas antioxidants in other teas were relatively slower released.