• Korean Journal of Clinical Pharmacy
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• v.32 no.1
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• pp.27-36
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• 2022

Background: Medication-related problems (MRPs) frequently occur during the discharge period. Elderly patients, particularly, are at high risk for these problems due to polypharmacy and the use of potentially inappropriate medications. The purpose of this study was to build and implement collaboration between general hospital and community pharmacies to address MRPs among high-risk elderly patients before/after discharge. Methods: This retrospective study was conducted between June and December of 2020. The inclusion criteria were patients with aged ≥65 years; residents of Jeonju; discharged from Jeonbuk National University hospital; either on medication of exceeding 10 medications (or high-risk medications) after hospitalization through the emergency room, or having severe illness. Patients received medication reconciliation and counselling by hospital pharmacists before discharge and home-visit pharmaceutical care as follow-up by community pharmacists after discharge. Results: Twenty-two patients agreed to home-visit pharmaceutical services. Fifteen and 11 patients completed the first and second home-visit pharmaceutical care service, respectively. Forty-two MRPs were identified in 15 patients. The types of high-frequency MRPs were incorrect administration of drug, adverse drug reactions, medication non-compliance, drug-drug interactions, lifestyle modifications, and expired medication disposal. After consultation with the pharmacist, 34 out of 42 MRPs were resolved. Conclusions: Transitional care for high-risk elderly patients before and after discharge was successfully built and implemented through a collaboration between general hospital and community pharmacies. This study suggests that home-visit pharmaceutical services may have positive effects on the safe use of drugs during the transition period; however, additional research is needed to expand on these findings.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.16 no.2
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• pp.207-213
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• 2009

Purpose: This study was done to examine how medication contamination in a single-dose glass ampule is affected by minute glass flakes generated in different methods of cutting the ampule. Method: Sixty medication-containing glass ampules were randomly assigned to two groups. The number of glass flakes, resulting from two different cutting methods (with cotton and without cotton), were counted under the microscope. Contamination was evaluated by extracted the medication with a syringe and culturing it in E. coli, coliform, and aerobic bacteria culture media. Result: Fewer glass flakes were found in the ampules when the ampule was cut with cotton. The use of cotton, however, did not significantly change the degree of drug contamination. Conclusion: Although minute glass flakes generated in the ampule cutting operation did not significantly contaminate the medication and the use of cotton decreased the number of glass flakes in the ampules, glass flakes injected into the blood and tissues of the patient remain a risk factor. Therefore, pre-filled syringes or syringes with filters would be alternative methods and safeguards against the possible injection of glass flakes generated while cutting the ampule.

• Korean Journal of Clinical Pharmacy
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• v.25 no.4
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• pp.254-263
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• 2015

Objectives: The present study assessed the prevalence of the potentially inappropriate medication (PIM) use in Korean elderly patients with Parkinson's disease. In addition, this study examined risk factors that affect PIM use. Method: A retrospective, observational study was conducted using Korean National Health Insurance claims database of 2009. PIM use in Parkinson's disease patients aged 65 years or older was examined based on 2012 Beers Criteria. Multivariable logistic regression was conducted to identify risk factors for PIM use. Results: Among 5,277 elderly patients with Parkinson's disease, 88.9% of patients used PIM(s) at least once. The average number of PIM items used per patient was 4.2. PIM use ratio, the proportion of total amount of PIMs to all medications per patient, was 12.6%. Frequently used PIM therapeutic classes were benzodiazepines (32.7%), first-generation antihistamines (19.2%), and prokinetics (17.5%). Individual PIMs most commonly used included chlorpheniramine (11.4%), levosulpiride (10.9%), diazepam (9.0%), and alprazolam (7.6%). Women (odds ratio [OR] 1.14, 95% confidence interval [CI] 1.11-1.16), medical aid (OR 1.18, 95% CI 1.15-1.21), and long-term facilities (OR 2.43, 95% CI 2.22-2.65) were shown to be risk factors associated with PIM use. Of particular, wide variation in PIM use was associated with the types of healthcare facility. Conclusion: The PIM prevalence was very high in elderly Parkinson's disease patients. Nationally effective and systematic efforts to identify and prevent PIM use should be made to ensure patient safety and to improve quality of care in the elderly.

• Child Health Nursing Research
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• v.28 no.4
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• pp.259-268
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• 2022

Purpose: Nursing students are susceptible to medication safety incidents in the neonatal intensive care unit (NICU) related to a lack of communication experience. The purpose of the present study was to investigate the impact of a NICU medication safety simulation (NMSS) focusing on communication clarity, patient hand-off confidence, and patient safety competency in senior-year nursing students. Methods: The study utilized a nonequivalent control group pretest-posttest design. In total, 60 nursing students were assigned to two groups. The experimental group participated in the NMSS, which included three medication error scenarios. Pairs of students completed the scenarios together in 10 to 20 minutes. Data were analyzed using the chi-squared test, independent t test, and ANCOVA. Results: The experimental group showed significant improvements in communication clarity (p=.015), and patient safety competency (p<.001) compared to the control group. Using the pretest values as covariates, patient hand-off confidence scores significantly increased (p=.027). Conclusion: Implementing the NMSS focusing on communication in the pediatric nursing curriculum helped students to communicate clearly and concisely about medication errors, and its use is recommended to promote patient safety competency in the NICU.

• Korean Journal of Clinical Pharmacy
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• v.23 no.3
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• pp.197-205
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• 2013

Background: Many factors including drugs, dietary supplements, and food intake can affect the development and organ formation of fetuses. Because of this, subject tends to avoid consuming things like coffee, alcohol, or cigarettes due to the risks they pose during pregnancy. Therefore, analysis of drugs and favorite food consumption is needed and important to ensure safe health management for subject. Purpose: This study was conducted domestically to analyze these factors in South Korea. Method: The survey was conducted from pregnancy-related online communities for six days and the survey results were received via email for analysis. Result: A total of 127 subjects answered the questionnaire via email; the characteristics of subjects are widely varied in their ages, education levels, job statuses, and residences. The questionnaire included the intake of dietary supplements during pregnancy including vitamins and the result showed that the subjects took 2.23 different kinds of supplements on average. In order of highest frequency, 101 subjects took multivitamins; 79 subjects took an iron supplement; 30 subjects took analgesics; 20 subjects took prescribed antipyretic and medication for upper respiratory diseases; 12 subjects took antibiotics; 7 subjects took antiemetics. Their compliances were different in each medication categories. Only 8% of subjects answered that they had asked a pharmacist for medication information during pregnancy. In addition, 78% of subjects answered that they never counseled with anyone about pregnancy related medication use. Conclusion: In conclusion, many subjects took medication including dietary supplements. The role of pharmacists should be actively developed to improve subject care such as education about subject's medication uses and their food consumption behavior.

• YAKHAK HOEJI
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• v.55 no.3
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• pp.195-202
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• 2011

Generic medication market has been increased for economic reasons in Korea. Health authorities worldwide recommend the use of generic medications nowadays. However, patients in Korea are not familiar with the generic medications and considerable percent of those do not know the definition of the generic medications. The purpose of this study was to evaluate adults' knowledge and perception on the generic medications at community pharmacies in Korea. This study was a 11-questionnaire survey conducted from August 9, 2010 to August 27, 2010. Of the 204 respondents, 63 (30.9%) responded that they knew what a generic medication was, but only 16 (25.4%) of those answered that generic medications had the same efficacy as brand medications. When pharmacists were the source of generic medication information, more patients reported having knowledge about the definition of generic medications correctly compared with other sources. Patients with negative experience with generic medications within 6 months were more reluctant to generic substitution suggested by a pharmacist than those with positive experience. Based on the results of this study, further studies should be conducted to establish the best way to provide generic medication information for patients.

• YAKHAK HOEJI
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• v.47 no.6
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• pp.390-397
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• 2003

It is common that geriatric patients are on several medications at the same time. With this situation on hand, this study has collected prescriptions of individual geriatric patient and investigated possible drug interactions. In order to minimize the drug interactions and protect those patients from adverse reactions of medication, the gradual implementation and management of the medication history of each individual patient, the establishment of medication counseling system on medicines particularly in need of obligatory advice, the use of an inspection system on drug interactions at the time of prescription, and the implementation of a patient monitoring system on the drugs with narrow margin of safety at hospitals.

• Journal of Haehwa Medicine
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• v.8 no.2
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• pp.191-210
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• 2000

The Literatual Study on Treatment of Toothbleeding Through the literatual study on treatment of toothbleeding, we concluded as follows, 1. The causes of the toothbleeding are divided into heat of stomach (胃熱) and deficiency of renal (腎虛). If caused by heat of stomach, the treatment methods are Ryang-Hyul-Ji-Hyul(凉血止血), Cheong-Yul-Sa-Hwa(淸熱瀉火). If caused by deficiency of renal, the treatment methods are Ryang-Hyul-Ji-Hyul(凉血止血), Ja-Eum-Gang-Hwa(滋陰降火). 2. The medications are several - taking a medicine for internal use(內服法), keeping with one's mouth full of an infusion and spoutting it Haamsoobup(含漱法), and others like taking a medicine for external use(外用法) only. 3. The treatment drugs divided by medication are as follows : Taking a medicine for internal use : Cheongwesan(淸胃散), Gamroeum(甘露飮), Joweseunggitang(調胃承氣湯), Seogagjihwangtang(犀角地黃湯), Yugmijihwangtang(六味地黃湯), Palrnihwan(八味丸), Soansinhwan(小安腎丸) etc... Haamsoobup : Gudogeum(救毒飮), Jihwangtang(地黃湯), Mangchosan(莽章散) etc... Taking a medicine for external use : Pilseungsan(必勝散), Rogposan(綠包散, Hyunggeousan(荊槐散), Bingoksan(氷玉散), Sahyangsan(麝香散), Ulgeumsan(鬱金散), Yongnoisan(龍腦激) are used. 4. A coposition of the medication : Cheong-Yul medicine(淸熱藥), Bo-IK medicine(補益藥), Ji-Hyul medicine(止血藥), Gae-Gyu medicine(開竅藥), Su-sap medicine(收澁藥) are mainly used. Cheong-Yul medicine : Rehmanniae Radix(鮮地黃), Moutan Cotex(牧丹皮), Coptidis Rhizoma(黃連), Scutellariae Radix(黃芩) Bo-Ik medicine : Glycyrrhizae Radix(甘草), Angelicae gigantis Radix(當歸), Rehmanniae Radix Preparat(熟地黃), Ginseng Radix(人蔘) Ji-Hyul medicine : Biotae Cacumen(側柏葉), Sophorae Flos(槐花), Typhae Pollen(蒲黃) Gae-Gyu medicine : Moschus(麝香), Bomeolum(氷片) Su-sap medicine : Alumem(白礬) 5. A result of the observation on the medication : Taking a medicine for internal use : Glycyrrhizae Radix, Rehmanniae Radix Preparat, Rehmanniae Radix, Moutan Cortex, Scutellariae Radix are used. Yugmijihwangtang and Cheong-Yul medicine are mainly used. Taking a medicine for external use : Alumem, Moschus, Salt(鹽), Asari herba cum Radice(細辛) are mainly used. Especially there is a method that uses a burnt drug. Haamsoobup and taking a medicine for external use : Medicines of Cheong-Yul-Ryang-Hyul(淸熱凉血) and Su-Ryum-Ji-Hyul(收斂止血) are used.

• The Journal of the Korea Contents Association
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• v.16 no.9
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• pp.791-805
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• 2016

The purpose of this study was to understand the essential meanings in experiences of medication misuse and abuse behavior in elderly people with chronic disease in community. The participants were 10 patients with chronic disease over 65 ages who were selected by convenience sampling. Data were collected through individual in-depth interviews from February to May 2014, and were analyzed using Colaizzi (1978)'s phenomenological analysis method. As a results, the essential meanings and structure of medication misuse and abuse behavior experience in elderly people with chronic disease were derived into five clusters of themes as follows: 'Burden on the medications', 'Anxiety about the side effect of the medications or the disease exacerbation', 'There is no alternative other than the medications', 'Expectations of the medications effect for my criteria', 'Lack of understanding on the correct medication use'. The results of this study contributed to promoting a deeper understanding of medication misuse and abuse behaviors in elderly people with chronic disease, and provided for the basic data of strategic development for the prevention of medication misuse and abuse behaviors from the perspective of elderly people with chronic disease in community.

• Journal of Korea Entertainment Industry Association
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• v.14 no.2
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• pp.213-224
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• 2020

Purpose: This study is a descriptive and secondary analytical study that uses panel data to identify the factors of medication adherence to improve life care of hypertensive patients. Methods: The subjects of this study were 2,484 patients who were taking medication after hypertension using Korea Medical Panel 2015 data (β-version 1.0). Data analysis was performed using Chi-Square, Scheffe's test, and logistic regression using SPSS/win 22.0. Results: The level of medication adherence in patients with hypertension was 94.2%. The factors of medication adherence were gender and age in Model I of demographic factors, and the presence of disability, smoking, and drinking in Model II. Model III, which added drug use factors, was identified as drinking, drug duration, side effects, drug satisfaction, and payment of drug costs. Conclusion: In order to improve life care for hypertension patients, education and interventions on the importance of take medication and side effects of medications and how to take them will be needed in the early stages of diagnosis.