• 대한방사선방어학회:학술대회논문집
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• 대한방사선방어학회 2010년도 춘계 학술발표회 및 심포지엄
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• pp.166-167
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• 2010

• Korean Journal of Acupuncture
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• 제29권2호
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• pp.315-326
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• 2012

Objectives : The new health technology assessment system was introduced in April 2007. The purpose of new health technology assessment is assessing safety and efficacy in deciding a behavior of new health technology according to the Health Insurance Act. This study aims to understand the present status of new health technologies of Korean medicine. Methods : This research introduces new health technologies and their present status, and searches for a development direction for the new health technology of Korean medicine in the future. Results : Thirty seven cases(3%) of Korean medicine doctors who utilized new health technologies application were found. In the status about new health technologies application by technologies assortment, diagnostic test techniques were used more often than treatment skills. New medical technology that included korean medicine doctor as actual user was only one item, i.e. HCV antibody test. Conclusions : In order for the new health technology of korean medicine to settle down well, continuous interest and efforts of both government and medical community are necessary.

• 한국응급구조학회지
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• 제23권1호
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• pp.147-155
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• 2019

Purpose: This study aimed to analyze the research trends of the articles published in the Korean Journal of Emergency Medical Services in the past 10 years. Methods: A total of 236 articles published between 2009 and 2018 were analyzed. For analysis of the collected data, frequencies and percentages were calculated using SPSS 23 (IBM, Armonk, NY, USA). Results: Most of the articles (47.9%, 113) were authored by 2 researchers, and most first authors were affiliated with university (81.4%, 192). Most of the articles were presented with 3 key words (34.3%, 81), and the most studied subjects of emergency medical technology was clinical researches (26.7%, 63). The majority of the research was performed quantitatively (99.6%, 235) and retrospectively (72.5%, 171), and research design was the most surveyed (68.2%, 161). For the majority of articles, the size of the sample was less than 100 (35.6%, 84), and the study participants were students (38.1%, 91). Only 12.7% (40) of the articles were reviewed by institutional review boards. Conclusion: In future studies on emergency medical technology, active participation of field emergency workers is needed. In addition, qualitative and prospective studies should be conducted on various types of research subjects.

• 한국응급구조학회지
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• 제3권1호
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• pp.43-54
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• 1999

This study is attempted for the purpose of clearly understanding the stressors which emergency medical technology students experience during clinical practice, giving guidance in desirable direction and improvement of clinical practice, and giving the basic materials so that emergency medical technology students may practice effectively. The design of this study was a descriptive survey. The subjects in this study were 59 emergency medical technology students who were 2nd grade in D college. The collection of questionnaires took 3 days from September 1, 1999 to September 3, 1999. This researcher explained the purpose of this study to students, after they agreed to this survey, the researcher gave the questionnaire to them, had them answer the questions and collected the questionnaire immediately. Data analysis included percentage, mean and standard deviation, t-test and ANOVA trough SPSS computer program. The results of this study are, briefly, as follows; 1. In 'satisfaction-degree to specializing in the science of emergency medical technology' 27.1% of the subjects is revealed as 'satisfied' and in 'satisfaction-degree of clinical practice', 8.5% of the subjects is revealed as 'satisfied'. 2. Viewed from each of the categories of stressors which emergency medical technology students experience during clinical practice, 'ideals and values' is the category in which emergency medical technology students experience most severe stress at a mean 3.25 and 'personal relations' is the category in which emergency medical technology students experience mildest stress at a mean 2.82. The total stress degree mean is 3.06, which emergency medical technology students experience during clinical practice is revealed as 'moderate' stress. 3. Considering the stressor involved in each category, the results are as follows; (1) In 'environment', 'orientation to the hospital before clinical practice' is revealed as the most severe stressor at a menu 3.44. (2) In 'personal relations', 'relations with doctor and nurse' is revealed as the most severe stressor at a mean 3.59. (3) In 'role', 'unilaterally when their role is seems to be obscure' is revealed as the most severe stressor at a mean 4.10. (4) In 'ideals and values', 'difference between college practice and hospital practice' is revealed as the most severe stressor at a mean 3.88. (5) In 'activity', 'repetition of simple and functional work during clinical practice' is revealed as the most severe stressor at a mean 3.98. (6) In 'total stress factors', 'unilaterally when their role is seems to be obscure' is revealed as the most severe stress factor at a mean 4.10 and 'relations with comrade students' is revealed as the stress factor causing mildest stress at a mean 2.20. 4. Considering the relationship between the categories of stressors and the general characteristics, the results are as follows; (1) 'Environment' is revealed as being positively correlated with 'satisfaction degree of clinical practice'(F=3.53, p= .0359). (2) 'Ideals and values' is revealed as being correlated with 'sex'(t=-2.31, p= .0240) and 'satisfaction degree of clinical practice'(F=3.31, p= .0438).

• 반도체디스플레이기술학회지
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• 제13권1호
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• pp.113-116
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• 2014

This paper has been forged to suggest 'Medical Information Searching System'. This system sets itself to conduct searching of medical information stored in a wide variety of medical institutions. This system aims to suggest a flexible, compatible and effective standard on medical information searching through this. So, In this paper, we present a framework to help medical institutions search the requiring medical information in conjunction with analysis on 'medical information request'.

• Asian Pacific Journal of Cancer Prevention
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• 제16권14호
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• pp.5607-5611
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• 2015

Thousands of people die each year from cancer due to occupational causes. To reduce cancer in workers, preventive strategies should be used in the high-risk workplace. The effective prevention of occupational cancer requires knowledge of carcinogen agents. Like other areas of healthcare industry, occupational health has been affected by information technology solutions to improve prevention, early detection, treatment and finally the efficiency and cost effectiveness of the healthcare system. Information technology solutions are thus an important issue in the healthcare field. Information about occupational cancer in information systems is important for policy makers, managers, physicians, patients and researchers; because examples that include high quality data about occupational cancer patients and occupational cancer causes are able to determine the worker groups which require special attention. As a result exposed workers who are vulnerable can undergo screening and be considered for preventive interventions.

• 한국정보통신학회논문지
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• 제19권9호
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• pp.2100-2106
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• 2015

최근 고령화로 인한 건강에 대한 관심이 증가되고 있다. 이는 만성질환의 의료비용 증가에 대한 요구사항이 뚜렷이 나타나고 있으며, 소득증대와 삶의 질 향상으로 새로운 첨단의료기술이 필요한 상황으로 기존의 의료기술에 정보통신기술을 연계하여 첨단기술을 적용한 선진국 형 의료기술의 표준화가 시급하다. 정보통신기술의 표준화 선점경쟁에 WBAN (Wireless Body Area Network)과 여러 가지 무선통신 기술의 표준을 살펴보고, 양질의 의료서비스 제공을 통한 전 국민의 의료서비스 질 향상 및 의료기술 강국으로 가기위한 환경조성이 필요하다. 따라서, 본 연구에서는 의료기술과 정보통신기술을 융합할 때 필요한 구성과 연관기술의 관계를 설명하고, 첨단 의료기기로 발전을 위한 정보통신 기술의 표준들을 정리해 보고자 한다.

• 대한의생명과학회지
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• 제7권4호
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• pp.181-190
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• 2001

This study was designed to investigate the effects of reactive oxygen species (ROS) on DNA stability in human spermatozoa. To verify human spermatozoa were incubated with xanthine-xanthine oxidase (X 100$\mu$M-XO 50 mlU ~ 400 mIU), $H_2O_2$ (125 $\mu$M ~ 1 mM), sodium nitroprusside (SNP 0.1 $\mu$M ~ 100 $\mu$M) or lymphocyte. Otherwise, spermatozoa were incubated under low $O_2$ (5%) condition. Damage of sperm DNA was analyzed by single cell electrophoresis (Comet assay) and flow cytometry after acridine orange staining. In the presence of ROS, there was increase in DNA damage. The rate of DNA single strand breakage (9.0$\pm$1.0% ~ 46.0$\pm$4.6%) and DNA fragmentation (7.51$\pm$1.0% ~ 29.5$\pm$4.6%) were similar regardless of the kinds of ROS and exposure time. DNA damage in the lower $O_2$ condition (5%) was lower than ambient $O_2$ condition (20%). Taken together, it suggested that sperm DNA might be damaged by ROS. In the presence of ROS, increase in DNA damage and chromatin instability was obvious in spite of short exposure. Although present study reconfirmed that sperm incubation in the low concentration of ROS have the benefit m the induction of capacitation and Ah, the increase in DNA damage by ROS and possible genetic problem should be considered before the human trials.

• 대한의사협회지
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• 제61권11호
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• pp.687-698
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• 2018

Inappropriate antibiotic use significantly contributes to antibiotic resistance, resulting in reduced antibiotic efficacy and an increased burden of disease. The objective of this study was to investigate the characteristics of prescribers whose antibiotics use was high and to explore factors affecting the use of antibiotics by medical institutions. This study analyzed the National Health Insurance claims data from 2015. Antibiotic prescription data were analyzed in terms of the number of defined daily doses per 1,000 patients per day, according to the World Health Organization anatomical-therapeutic-chemical classification and methodologies for measuring the defined daily dose. We investigated the characteristics of prescribers and medical institutions with high antibiotic use. Multivariate regression analyses were performed on the basis of characteristics of the medical institution (number of patients, type of medical institution [hospital or clinic], age of the physician, etc.). The number of patients and number of beds were found to be significant factors affecting antibiotic use in hospitals, and the number of patients, region, and medical department were significant factors affecting antibiotic use at the level of medical institutions. These findings are expected to help policy-makers to better target future interventions to promote prudent antibiotic prescription.

• Journal of Microbiology and Biotechnology
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• 제30권7호
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• pp.996-1004
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• 2020

Various genetically engineered microorganisms have been developed for the removal of heavy metal contaminants. Metal biosorption by whole-cell biosorbents can be enhanced by overproduction of metal-binding proteins/peptides in the cytoplasm or on the cell surface. However, few studies have compared the biosorption capacity of whole cells expressing intracellular or surface-displayed metal-adsorbing proteins. In this study, several constructs were prepared for expressing intracellular and surface-displayed Ochrobactrum tritici 5bvl1 ChrB in Escherichia coli BL21(DE3) cells. E. coli cells expressing surface-displayed ChrB removed more Cr(VI) from aqueous solutions than cells with cytoplasmic ChrB under the same conditions. However, intracellular ChrB was less susceptible to variation in extracellular conditions (pH and ionic strength), and more effectively removed Cr(VI) from industrial wastewater than the surface-displayed ChrB at low pH (<3). An adsorption-desorption experiment demonstrated that compared with intracellular accumulation, cell-surface adsorption is reversible, which allows easy desorption of the adsorbed metal ions and regeneration of the bioadsorbent. In addition, an intrinsic ChrB protein fluorescence assay suggested that pH and salinity may influence the Cr(VI) adsorption capacity of ChrB-expressing E. coli cells by modulating the ChrB protein conformation. Although the characteristics of ChrB may not be universal for all metal-binding proteins, our study provides new insights into different engineering strategies for whole-cell biosorbents for removing heavy metals from industrial effluents.