Journal of the Korean Medical Association (대한의사협회지)

Korean Medical Association (대한의사협회)
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Analysis of factors affecting antibiotic use at hospitals and clinics based on the defined daily dose

병원 및 의원급 일일사용량 기준 항생제 사용량에 영향을 미치는 요인

  • Lee, Eun Jee (Pharmaceutical & Medical Technology Research Team, Department of Research, Health Insurance Review & Assessment Service) ;
  • Lee, GeunWoo (Pharmaceutical & Medical Technology Research Team, Department of Research, Health Insurance Review & Assessment Service) ;
  • Park, Juhee (Pharmaceutical & Medical Technology Research Team, Department of Research, Health Insurance Review & Assessment Service) ;
  • Kim, Dong-Sook (Pharmaceutical & Medical Technology Research Team, Department of Research, Health Insurance Review & Assessment Service) ;
  • Ahn, Hyeong Sik (Department of Preventive Medicine, Korea University College of Medicine)
  • 이은지 (건강보험심사평가원 연구조정실) ;
  • 이근우 (건강보험심사평가원 연구조정실) ;
  • 박주희 (건강보험심사평가원 연구조정실) ;
  • 김동숙 (건강보험심사평가원 연구조정실) ;
  • 안형식 (고려대학교 의과대학 예방의학교실)
  • Received : 2018.09.14
  • Accepted : 2018.10.02
  • Published : 2018.11.20
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Abstract

Inappropriate antibiotic use significantly contributes to antibiotic resistance, resulting in reduced antibiotic efficacy and an increased burden of disease. The objective of this study was to investigate the characteristics of prescribers whose antibiotics use was high and to explore factors affecting the use of antibiotics by medical institutions. This study analyzed the National Health Insurance claims data from 2015. Antibiotic prescription data were analyzed in terms of the number of defined daily doses per 1,000 patients per day, according to the World Health Organization anatomical-therapeutic-chemical classification and methodologies for measuring the defined daily dose. We investigated the characteristics of prescribers and medical institutions with high antibiotic use. Multivariate regression analyses were performed on the basis of characteristics of the medical institution (number of patients, type of medical institution [hospital or clinic], age of the physician, etc.). The number of patients and number of beds were found to be significant factors affecting antibiotic use in hospitals, and the number of patients, region, and medical department were significant factors affecting antibiotic use at the level of medical institutions. These findings are expected to help policy-makers to better target future interventions to promote prudent antibiotic prescription.

Keywords

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