• Journal of Biomedical Engineering Research
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• v.42 no.4
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• pp.150-158
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• 2021

Intracranial hemorrhage (ICH) refers to acute bleeding inside the intracranial vault. Not only does this devastating disease record a very high mortality rate, but it can also cause serious chronic impairment of sensory, motor, and cognitive functions. Therefore, a prompt and professional diagnosis of the disease is highly critical. Noninvasive brain imaging data are essential for clinicians to efficiently diagnose the locus of brain lesion, volume of bleeding, and subsequent cortical damage, and to take clinical interventions. In particular, computed tomography (CT) images are used most often for the diagnosis of ICH. In order to diagnose ICH through CT images, not only medical specialists with a sufficient number of diagnosis experiences are required, but even when this condition is met, there are many cases where bleeding cannot be successfully detected due to factors such as low signal ratio and artifacts of the image itself. In addition, discrepancies between interpretations or even misinterpretations might exist causing critical clinical consequences. To resolve these clinical problems, we developed a diagnostic model predicting intracranial bleeding and its subtypes (intraparenchymal, intraventricular, subarachnoid, subdural, and epidural) by applying deep learning algorithms to CT images. We also constructed a visualization tool highlighting important regions in a CT image for predicting ICH. Specifically, 1) 27,758 CT brain images from RSNA were pre-processed to minimize the computational load. 2) Three different CNN-based models (ResNet, EfficientNet-B2, and EfficientNet-B7) were trained based on a training image data set. 3) Diagnosis performance of each of the three models was evaluated based on an independent test image data set: As a result of the model comparison, EfficientNet-B7's performance (classification accuracy = 91%) was a way greater than the other models. 4) Finally, based on the result of EfficientNet-B7, we visualized the lesions of internal bleeding using the Grad-CAM. Our research suggests that artificial intelligence-based diagnostic systems can help diagnose and treat brain diseases resolving various problems in clinical situations.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.10 no.8
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• pp.1407-1413
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• 2006

The field of medical images has been digitalized as the development of computer and the digitalization of the medical instruments. As a result it causes a lot of problems such as an illegal copy related to medical images and property right of the medical images. Therefore, digital watermarking is used for discrimination whether the data are modified or not. It is also used to protect both the property right of medical images and the private life of many patients. The proposed theories, the Non-blind and the Blind method, have two problems. One is needed an original image and the other is using a gaussian watermarking. This paper proposes the new Blind Watermarking using binary images in order to easily recognize the results of watermark. This algorism is described that an watermark of a binary image is wavelet-transformed, and then a transformed watermark is inserted in medium-band of frequency domains of original image by the Circular Input method. This method don't have any loss when image didn't have any attack. As a result Watermark can be perfectly extracted by using this algorithm. And Maximam PSNR value is improved 3.35dB. This algorithm will be improved by using gray level image and color image.

• Journal of the Institute of Electronics and Information Engineers
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• v.53 no.12
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• pp.175-179
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• 2016

Recent advances in technology of medical image have made surgical simulation that is helpful to diagnosis, operation plan, or education. Improving and enhancing the medical imaging have led to the availability of high definition images and three-dimensional (3D) visualization, it allows a better understanding in the surgical and educational field. The Real human field of view is stereoscopic. Therefore, with just 2D images, stereoscopic reconstruction process through the surgeon's head, is necessary. To reduce these process, 3D images have been used. 3D images enhanced 3D visualization, it provides significantly shorter time for surgeon for judgment in complex situations. Based on 3D image data set, virtual medical simulations, such as virtual endoscopy, surgical planning, and real-time interaction, have become possible. This article describes principles and recent applications of newer imaging techniques and special attention is directed towards medical 3D reconstruction techniques. Recent advances in technology of CT, MR and other imaging modalities has resulted in exciting new solutions and possibilities of shoulder imaging. Especially, three-dimensional (3D) images derived from medical devices provides advanced information. This presentation describes the principles and potential applications of 3D imaging techniques, simulation and printing in shoulder and elbow practice.

• Journal of radiological science and technology
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• v.28 no.2
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• pp.111-115
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• 2005

The quality of image from the system that creates medical images by using X-ray depends on the various different reasons such as the X-ray generator, the subject and the image transmission medium. In other words, thereare various factors existing that can influence on the quality of image from the moment when the X-ray is generated and until the final image is created. Therefore, the operator who creates images at the clinical site should make continuous evaluation and observation from the final image. There are various methods of evaluating the medical images, but it is assumed that the MTF measurement method can be suitable for measuring actual or effective resolution. So in this study, the MTF measurement method by using X-ray film has been avoided and the MTF features according to the deterioration of the X-ray system have been measured by using the software (the program used Borland C++ builder software and LEAD tools software) that can measure the MTF of the digital medical images. As the result of this measurement, it has been found out through the MTF graph that the resolution and sharpness from the old x-ray generator with a many years of using and many numbers of times of using were deteriorated for the quality of image comparing to those from the new system. Also a simple and easy measurement method for the MTF from the digital medical images can be obtained in this study.

• Nuclear Medicine and Molecular Imaging
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• v.42 no.2
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• pp.172-180
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• 2008

PET/CT fused image with anatomical and functional information have improved medical diagnosis and interpretation. This fusion has resulted in more precise localization and characterization of sites of radio-tracer uptake. However, a motion during whole-body imaging has been recognized as a source of image quality degradation and reduced the quantitative accuracy of PET/CT study. The respiratory motion problem is more challenging in combined PET/CT imaging. In combined PET/CT, CT is used to localize tumors and to correct for attenuation in the PET images. An accurate spatial registration of PET and CT image sets is a prerequisite for accurate diagnosis and SUV measurement. Correcting for the spatial mismatch caused by motion represents a particular challenge for the requisite registration accuracy as a result of differences in PET/CT image. This paper provides a brief summary of the materials and methods involved in multiple investigations of the correction for respiratory motion in PET/CT imaging, with the goal of improving image quality and quantitative accuracy.

• Journal of the Korean Society for Industrial and Applied Mathematics
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• v.2 no.1
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• pp.131-139
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• 1998

With the rapid development of communication technology and widespread uses of internet service, utilization of internet-based medical information systems which transmitts moving pictures of medical objects is becoming a common practice. The internet-based medical information service prvovides richer information than conventional services such as touch-tone telephone, personal computers e-mails, or pagers, because "a picture is worth a thousand words". However, the systems passively transmits moving pictures of the medical objects to the users, and thus the system cannot intelligently adjust itself to provide better service. As the tradeoff exists between transmission speed and quality of the image, there is a need that moving pictures be analyzed to adjust the trnasmission speed and image quality. When very little difference between consecutive images are detected, the system can automatically increase the size of the image files, thus enhancing the quality of image. In contrast, the system should increase the number of images to send more pictorial information by sacrificing the quality of each individual image, when a significant difference is detected. In this paper an adaptive filtering technique is introduced which adjusts the quality of image and transmission speed according to a clinical situation in hospital.

• Journal of Biomedical Engineering Research
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• v.20 no.3
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• pp.265-274
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• 1999

In this paper, we propose a novel interframe coding algorithm especially appropriate for 3-D medical images. The proposed algorithm is based on a video coding algorithm using motion estimation/ compensation and transform coding. In the algorithm, warping is adopted lor motion compensation (MC). Then, by using adaptive mode selection, a motion compensated residual image and original image are mixed up in the wavelet transform domain for improvement in coding performance. The mixed image is then compressed by the zerotree coding method. We prove that the adaptive mode selection technique in the wavelet transform domain is very useful lor 3-D medical image coding. Simulation results show that the proposed scheme provides good performance regardless of inter-slice distance and is prospective for 3-D medical image compression.

• Journal of Information Processing Systems
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• v.13 no.1
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• pp.40-56
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• 2017

Since the progress of digital medical imaging techniques, it has been needed to compress the variety of medical images. In medical imaging, reversible compression of image's region of interest (ROI) which is diagnostically relevant is considered essential. Then, improving the global compression rate of the image can also be obtained by separately coding the ROI part and the remaining image (called background). For this purpose, the present work proposes an efficient reversible discrete cosine transform (RDCT) based embedded image coder designed for lossless ROI coding in very high compression ratio. Motivated by the wavelet structure of DCT, the proposed rearranged structure is well coupled with a lossless embedded zerotree wavelet coder (LEZW), while the background is highly compressed using the set partitioning in hierarchical trees (SPIHT) technique. Results coding shows that the performance of the proposed new coder is much superior to that of various state-of-art still image compression methods.

• Journal of radiological science and technology
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• v.42 no.2
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• pp.119-130
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• 2019

Positron emission tomography (PET) is widely used imaging modality for effective and accurate functional testing and medical diagnosis using radioactive isotopes. However, PET has difficulties in acquiring images with high image quality due to constraints such as the amount of radioactive isotopes injected into the patient, the detection time, the characteristics of the detector, and the patient's motion. In order to overcome this problem, we have succeeded to improve the image quality by using the dynamic image reconstruction method based on singular value decomposition. However, there is still some question about the characteristics of the proposed technique. In this study, the characteristics of reconstruction method based on singular value decomposition was estimated over computational simulation. As a result, we confirmed that the singular value decomposition based reconstruction technique distinguishes the images well when the signal - to - noise ratio of the input image is more than 20 decibels and the feature vector angle is more than 60 degrees. In addition, the proposed methode to estimate the characteristics of reconstruction technique can be applied to other spatio-temporal feature based dynamic image reconstruction techniques. The deduced conclusion of this study can be useful guideline to apply medical image into SVD based dynamic image reconstruction technique to improve the accuracy of medical diagnosis.

• Progress in Medical Physics
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• v.18 no.3
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• pp.134-138
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• 2007

The current PET/CT system with high quality CT images not only increases diagnostic value by providing anatomic localization, but also shortens the acquisition time for attenuation correction than primary PET system. All commercially available PET/CT system uses the CT scan for attenuation correction instead of the transmission scan using radioactive source such as $^{137}Cs,\;^{68}Ge$. However the CT scan may substantially increase the patient dose. The purpose of this study was to evaluate quality of PET images reconstructed by CT attenuation map using various tube currents. in this study, images were acquired for 3D Hoffman brain phantom and cylindrical phantom using GE DSTe PET/CT system. The emission data were acquired for 10 min using phantoms after injecting 44.03 MBq of $^{18}F-FDG$. The CT images for attenuation map were acquired by changing tube current from 10 mA to 95 mA with fixed exposure time of 8 sec and fixed tube voltage of 140 kVp. The PET images were reconstructed using these CT attenuation maps. Image quality of CT images was evaluated by measuring SD (standard deviation) of cylindrical phantom which was filled with water and $^{18}F-FDG$ solution. The PET images were evaluated by measuring the activity ratio between gray matter and white matter in Hoffman phantom images. SDs of CT images decrease by increasing tube current. When PET images were reconstructed using CT attenuation maps with various tube currents, the activity ratios between gray matter and white matter of PET images were almost same. These results indicated that the quality of the PET images using low dose CT data were comparable to the PET images using general dose CT data. Therefore, the use of low dose CT is recommended than the use of general dose CT, when the diagnostic high quality CT is not required. Further studies may need to be performed for other system, since this study is limited to the GE DSTe system used in this study.