• Journal of The Korean Society of Clinical Toxicology
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• v.14 no.2
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• pp.78-82
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• 2016

Purpose: Green tea is known as a potent anti-oxidant, anti-carcinogen, and genetic protector. Glyphosate (N-phosphonomethyl glycine) is a widely used non-selective herbicide that causes DNA damage. The present study was conducted to investigate the protective effects of green tea in human blood lymphocytes exposed to glyphosate using the Sister Chromatid Exchange (SCE) frequency method. Methods: Peripheral blood was obtained from 10 volunteers and cultured through four different conditions. Four groups were divided into control, glyphosate only (300 ng/mL), glyphosate and low ($20{\mu}m$) concentrations of epigallocatechin gallate (EGCG) and glyphosate and high ($100{\mu}m$) concentrations of EGCG. Results: The glyphosate exposed groups had a higher mean SCE frequency ($10.33{\pm}2.50$) than the control group ($6.38{\pm}2.28$, p<0.001). The low concentrations of EGCG groups had a lower mean SCE frequency ($9.91{\pm}1.93$) than the glyphosate-only group, although this difference was not significant (p=0.219). However, the high concentration group ($9.49{\pm}1.85$) had a significantly lower SCE frequency than the glyphosate-only group (p=0.001). Conclusion: EGCG has a gene protective effect in human lymphocytes exposed to the genotoxicity of glyphosate in the case of high concentrations.

• Journal of Communications and Networks
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• v.16 no.4
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• pp.465-474
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• 2014

Wireless sensor network (WSN) is considered to be one of the most important research fields for ubiquitous healthcare (u-healthcare) applications. Healthcare systems combined with WSNs have only been introduced by several pioneering researchers. However, most researchers collect physiological data from medical nodes located at static locations and transmit them within a limited communication range between a base station and the medical nodes. In these healthcare systems, the network link can be easily broken owing to the movement of the object nodes. To overcome this issue, in this study, the fast link exchange minimum cost forwarding (FLE-MCF) routing protocol is proposed. This protocol allows real-time multi-hop communication in a healthcare system based on WSN. The protocol is designed for a multi-hop sensor network to rapidly restore the network link when it is broken. The performance of the proposed FLE-MCF protocol is compared with that of a modified minimum cost forwarding (MMCF) protocol. The FLE-MCF protocol shows a good packet delivery rate from/to a fast moving object in a WSN. The designed wearable platform utilizes an adaptive linear prediction filter to reduce the motion artifacts in the original electrocardiogram (ECG) signal. Two filter algorithms used for baseline drift removal are evaluated to check whether real-time execution is possible on our wearable platform. The experiment results shows that the ECG signal filtered by adaptive linear prediction filter recovers from the distorted ECG signal efficiently.

• Proceedings of the Korean Society of Computer Information Conference
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• 2016.01a
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• pp.125-128
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• 2016

본 논문에서는 다중 생체계측 장비를 CMCIS(Central Monitoring and Cardiology Information System) 기반의 통합 시스템에 연동하기 위한 MDEC(Medical Device Exchange Communication)의 설계 및 구현을 소개한다. MDEC은 6종의 계층장비의 신호를 받아 각 서버로 데이터를 전송할 수 있도록 설계하고 Linux OS을 포팅 하였다. 각 장비별 프로토콜에 대해 최소화된 기본 프로토콜을 정의하고 통신방법에 따라 UART 포트 혹은 USB 포트를 생체정보의 물리적 입력장치로 사용하였다. 호스트 서버와는 유무선 LAN울 통해 정보를 전달할 수 있게 하드웨어를 설계하였다. 본 연구의 결과는 CMCIS 기반의 통합 시스템을 구축하는 기반기술로 향후 효율적 의료서비스에 기여할 것으로 사료된다.

• Proceedings of the KOSOMBE Conference
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• v.1997 no.11
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• pp.478-481
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• 1997

A technique or the preparation of porous polyurethane vascular prostheses was investigated. Small-diameter vessels are not in general clinical use due to their limited long-term biocompatibility and low patency rates in experimental trial. These limits are mainly due to the failure of mechanical unction of the vascular grafts. This failure has been suggested to result partially from compliance mismatch. The long-term patency is considered to depend critically on the properties of the material and the fabrication process of the graft. So the control of pores is very important and main points to develop a available vascular grafts. Two-kind polymer sheets was compared. One was the porous PU-sheet made at room temperature by the solvent/non-solvent exchange. And the other was the porous PU-sheet which was fabricated by thermal phase transition and solvent-/non-solvent exchange using the thermal controller. The polymer sheets had a uniform pore size and pore occupation. According to the result of the above experiments, polyurethane solution was injected into a mold designed or U-type tube. The average pore size and pore occupation were easily changed by changing polyurethane concentration, freezing temperature, and methods. This technique can give a proper pore size ($10{\sim}45\;{\mu}m$) or tissue in growth, and suitable compliances or matching with arteries and veins. Besides, the fabrication of more complicated shaped vessels such as the U-type vascular grafts is easily controlled by using the fixed mold. this method might give a desired compliant graft or artificial implantation with the presently valid medical polymers.

• Journal of Radiation Protection and Research
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• v.28 no.1
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• pp.25-33
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• 2003

The automatic system for $^{67}Ga$ production using for the diagnosis of malignant tumor has been developed. A solvent extraction and an ion exchange chromatography were used for the separation $^{67}Ga$ from the irradiated enriched $^{68}Zn$. This system consisted of a solvent separation unit which was composed of micro conductivity cells, air supply tubes, solvent transfer tubes, solenoid valves and glasses, a PLC based controller and a PMU user interface unit for automation. The radiation exposure to the workers and the production time can both be reduced by employing this system during the $^{67}Ga$ production phase. After all, the mass production of $^{67}Ga$ with high efficiency was possible.

• Journal of Biomedical Engineering Research
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• v.26 no.5
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• pp.301-307
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• 2005

We introduce a new multimedia telemedicine system which is called Telemedicine for Real-time Emergency Multi-consultation(TREM), based on multiple connection between medical specialists. Due to the subdivision of medical specialties, the existing one-to-one telemedicine system needs be modified to a simultaneous multi-consulting system. To facilitate the consultation the designed system includes following modules: high-quality video, video conferenceing, bio-signal transmission, and file transmission. In order to enhance the operability of the system in different network environment, we made it possible for the user to choose appropriate data acquisition sources of multimedia data and video resolutions. We have tested this system set up in three different places: emergency room, radiologist's office, and surgeon's office. All three communicating systems were successful in making connections with the multi-consultation center to exchange data simultaneously in real-time.

• Journal of Korean Academy of Nursing
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• v.34 no.3
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• pp.467-476
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• 2004

Purpose: The purpose of this study was to identify the effect of the exchange of saline used in surgical procedures on surgical site infections. Method: Patients with stomach cancer were assigned to the experimental group or to the control group by random sampling, respectively. The experimental group received an exchange of saline during the operation right after the excision of the stomach in a gastrectomy but the control group did not. Data were collected from the medical charts of 34 patients from Dec. 1, 2002 through May 31, 2003. Result: The surgical site infection rate of the experimental group was 5.9% while surgical site infection rate of the control group was 17.6%. In total, the surgical site infection rate was 11.8%. The experimental group maintained a normal level of WBC on post operative day 3; however, the control group, showed an increase of WBC on post operative day 3. Conclusion: The exchange of saline used in an operation immediately after the excision of the stomach in a gastrectomy decreases the contamination level of saline used in the operation, and can prevent surgical patients from a surgical site infection.

• 대한예방의학회:학술대회논문집
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• 1998.10b
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• pp.256-257
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• 1998

• Journal of Korean Medical classics
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• v.20 no.1
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• pp.17-37
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• 2007

Basic summary of the medical administration: First of all, Liao Jin Yuan dynasties had broad cultural exchange between north and south that the two traditional medical administrations were closely linked which later formed a system that united as one. Establishment of governmental medical office and governmental medical education organization was the very first attempt in the history of the medical administration. The measure on promoting the social level of medical doctors has an important meaning on the growth of the medical field. Medical policy on prisoners was done under the new condition brought on from experience. Medicine not of China was broadly interchanged, medicine from Arab was spread throughout China, and the department on skeletal injuries and the dietary treatments had major development. At this era, under a overall expansion of politics, economy, culture and medicine, scholastic dispute on medicine triggered medical expansion.

• Proceedings of the Korean Institute of Interior Design Conference
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• 2005.10a
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• pp.235-236
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• 2005

A medical college is faculty which performs frequent experiments and holds lots of seminars for these reasons, this place was designed to exchange its concentration, taking its spatial psychology convenience and its functions into consideration. This space has been built up as the technological and multi-functional space to encourage it to accomplish special functions required by each of facilities, such as the president room, a main center of administration in the medical college, an audience chamber, an attached room, the room for alumni, preventive medicine and Micro biological diseases, a legal medicine lecture room, the room for basic medical science and a conference room.