• The Journal of Korean Medicine
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• v.40 no.3
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• pp.76-86
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• 2019

Objectives: This study aims to assess the Gyenggi-do support project of Korean medical treatment in subfertility in 2018. And we would like to propose a plan to improve the project by analyzing the results of the project. Methods: We got the medical records of 260 participants that personal information was deleted by the association of Korean Medicine in Gyenggi-do. We collected the participants' characteristics, treatment records, results of treatment, laboratory results and satisfaction survey results. We coded the data and analyzed them using SPSS 23 at 5% significance level. Results: After the treatment, 11.0% of participants became pregnant spontaneously. There was no significant change in blood test before and after the treatment and observation period, and there was no adverse event during the project. After the project, the satisfaction survey was conducted. 84.2% of participants answered that they were satisfied with the result of the treatment. Conclusions: We analyzed the results of Gyenggi-do support project of Korean medical treatment for infertile women in 2017 and 2018. This study suggests the effectiveness and safety of Korean medical treatment for infertile women.

• The Journal of Churna Manual Medicine for Spine and Nerves
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• v.2 no.2
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• pp.105-116
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• 2007

Objectives : Physical activity is known as beneficial to mental health like decreasing depression and stress. In this study, we tried to find out the relationship between body composition, stress, depression, and self-esteem with physical activity level. Methods : International Physical Activity Questionnaire(IPAQ)-short form, SRRS(Social readjustment rating scale), SRI(Stress response index), and BDI(Beck's depression index), SES(Self-esteem scale) were given to peri-menopausal women aged 45-55 and BMI$\geq$23kg/m2. They were given written consent and this study is performed under the permission of institutional review board of Kyung Hee East-west Neo Medical Center. Results : The mean of physical activity of total subjects was 2406MET-min/week(n=42). The physical activity of overweight(23kg/m2$\leq$BMI<25kg/m2) and obese(BMI$\geq$25kg/m2) permimenopausal women was 1428MET-min/week and 2970MET-min/week(p<0.05) respectively. When three levels of physical activity pattern(inactive, minimally active, and HEPA(Health-enhancing physical activity) active) was analyzed, all of them were heavily relied on the activity intensities of walking. The scores of BDI, SRRS, and SRI were lower and that of SES were higher in HEPA active group, not showing statical significance. Anger(subscale of SRI) measures were lower and SES measures were higher in HEPA active group than others among overweight women(p<0.05). Conclusions : The level of physical activity of peri-menopausal women was on the average, but the vigorous activity is thought to be necessary. The HEPA active group showed lower depression, stress and higher self-esteem than minimally active and inactive group.

• Journal of Ginseng Research
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• v.40 no.1
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• pp.86-89
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• 2016

This study compared the contents of prosapogenin depending on the extracting conditions of Red ginseng to provide basic information for developing Red ginseng-based functional foods. The content of ginsenoside Rg3 reached their maximum value at 24 h of extraction, followed by 36 h and 72 h of extraction at $100^{\circ}C$.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.12 no.1
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• pp.6-14
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• 2005

Purpose: This study was done to investigate the need to develop health promotion programs for adult women and to compare lifestyle, health status and quality of life in adult women in urban and rural areas. Method: The participants were women over 20 years old, 451 living in 3 cities and 436 living in 1 rural areas. Data collection was conducted from April 6 to August 30, 2004. Results: For lifestyle, the percentage of women having regular medical examinations, cholesterol tests, regular exercise, and high alcohol intake were significantly higher for urban women compared to the rural women. For health status, the percentage of women with health problems such as arthritic pain, urinary incontinence, pregnancy and postpartum complications, and the experience of violence were significantly higher for rural women compared to urban women. Rural women had significantly lower scores for health perception compared to urban women. For quality of life, rural women had significantly higher scores for quality of life, especially for the psychological wellbeing and stability subscales. Conclusion: The above findings indicate that it is necessary to develope a health promotion program which reinforces healthy lifestyle and health status for rural women, and quality of life, for urban women.

• Korean Journal of Clinical Pharmacy
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• v.16 no.2
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• pp.123-130
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• 2006

The study was aimed to recommend the ways for improving regulatory system of quasi-drugs in governmental authority by comparing with other countries. According to the regulations, the scope of quasi-drugs includes 3 categories of 1) the health aids made of textile, rubber and paper, 2) the health aids which have very minimal effects or no any effects on humans, and 3) disinfectants and pesticides. In US, these quasi-drugs in Korea are classified into 5 categories of medical device, cosmetics, OTC drugs, dietary supplements and pesticides. To improve quasi-drugs administration in Korea, it is concluded that several measures should be implemented : 1) establish clear criteria for classifying into quasi-drugs and more detailed guidelines on designation of quasi-drugs, 2) reform current regulations to meet 3-categories characteristics, supplement detailed guidelines on quasi-drugs administration for effective application process, and update relevant regulations for efficacy, safety and quality, 3) update quasi-drug monographs, 4) re-evaluate current classification of individual quasi-drugs, 5) develop comprehensive list by ingredients, 6) reform post-marketing management system for safety and quality, 7) strengthen the review agency function by increasing the number of experts, 8) develop the database for quasi-drugs for effective information management.

• The Journal of Korean Medicine
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• v.41 no.3
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• pp.32-54
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• 2020

Objectives: The purpose of this scoping review is to describe the research trends of postpartum healthcare for postpartum women, as well as to identify further direction for research in the area of postpartum healthcare. Methods: This study was conducted sequentially according to the Scoping Review Method referred to as 'frameworks of Arskey and O'Malley'. We searched for articles published as of May 15th, 2020 in seven Korean databases in order to obtain the data. A key term search strategy was employed, including terms such as "Postpartum period care", "Postpartum health", "Postpartum care", and "Postpartum status" to identify relevant studies. Results: Eighty-three articles were selected from a total of 259. The research has been undertaken steadily since 1997, particularly in the fields of Nursing and Korean medicine. In terms of study design, survey studies were the majority (48.2%), followed by interventions and experimental papers (32.5%). However, qualitative research areas are lacking. The research topics were largely divided into two categories: postpartum care characteristics and postpartum care interventions. The characteristics of postpartum care were highly connected with care for mental health. Among the postpartum care interventions, the most common employed was Korean medicine intervention. Conclusion: This study confirms that management of mental health during the postpartum period is necessary. In addition, it is necessary to identify the experiences of postpartum women and the effectiveness of a postpartum care intervention program through the utilization of qualitative research methods. In particular, such research is needed in the field of Korean medicine.

• Journal of Preventive Medicine and Public Health
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• v.31 no.1 s.60
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• pp.59-71
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• 1998

To examine the association of hypertension with cluster of obesity, abnormal glucose and dyslipidemia in Korean urban population, we conducted this cross-sectional study among 3027 men and 2127 women age 20-85 years who visited a prevention center between May 1991 and June 1995 for a multiphasic health check at St. Mary's Hospital, Seoul. By the self-administered questionnaire, the informations of educational attainments, monthly income, alcohol consumption, cigarette smoking, and physical excercise level were obtained. Height, weight, and blood pressure were measured by a trained nurse. The fasting blood sugar (FBS), total cholesterol, high density lipoprotein (HDL) cholesterol and triglyceride were tested by enzyme method. Low density lipoprotein (LDL) cholesterol was calculated by 'total cholesterol - HDL cholesterol - triglyceride/5'. For testing the differences of cardiovascular risk factors between hypertension and normotension group, 1-test and $\chi^2$-test were performed. For the age adjusted odds ratios of hypertension in persons with obesity, abnormal glucose, and dyslipidemia compared with normal, logistic regression was performed by using SAS pakageprograme. The results obtained were as follows: 1. Age, weight, body mass index(BMI), blood glucose, total cholesterol, LDL cholesterol, and triglyceride of hypertension group in men and women were significantly higher than normotension group, but height and HDL cholesterol of hypertension group only in women significantly lower than normotension group. The frequency of obesity $(BMI\geq25kg/m^2)$, abnormal glucose $(\geq\;120mg/dl)$, hypercholesterolemia $(\geq\;240mg/dl)$, lower HDL cholesterol (<45 mg/dl in women only), higher LDL cholesterol $(\geq\;160mg/dl)$, and hyper hypertriglyceridemia $(\geq\;250mg/dl)$ in hypertension group of men and women were significantly higher than normotension group. 2. Systolic and diastolic blood pressure were negatively correlated with hight, but positively with age, weight, BMI, total cholesterol, LDL cholesterol, and triglyceride in men and women. BMI was positively correlated with fasting blood sugar, total cholesterol, LDL cholesterol and triglyceride but negatively with HDL cholesterol. 3. The age adjusted odds ratios of hypertension were as follows in men and women : among persons who were obese compared with those nonobese, 2.53 (95% Confidence Intervals [C.I.] 2.08-3.07) and 2.22 (95%C.I. 1.71-2.87): among persons who were abnormal glucose compared with those normoglycemic, 1.43 (95%C.I 1.13-1.82) and 2.01 (95%C.I 1.36-2.94): and among persons who were dyslipidemia (hypercholesterolemia or lower HDL cholesterol or higher LDL cholesterol or hypertriglyceridemia) compared with those normal lipid, 1.59 (95%C.I 1.30-1.95) and 1.51 (95%C.I 1.16-1.96). After combined more than one risk factor, the odds ratios were increased. Among persons with cluster of obesity, abnormal glucose, and dyslipidemia, the odds ratio of hypertension was 2.25 (95%C.I 1.47-3.37) in men and 3.02 (95%C.I 1.71-5.30) in women. In conclusion, it was suggested that hypertension was associated with cluster of obesity, abnormal glucose, dyslipidemia in this Korean urban population.

• Journal of Oriental Medical Thermology
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• v.8 no.1
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• pp.39-47
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• 2010

Purpose : Most pregnant women avoid laking medicine and acupuncture treatment because of its affect on the unborn baby. However, for a healthy pregnancy, appropriate treatments are needed. Until now, there hasn't been much research about acupuncture therapy on pregnant women in Korea. so we decided to review the kinds of research that have been done in the recent 10 years. Methods : We researched for papers associated with pregnancy and acupuncture. Type of research was limited to randomized controlled trials in the recent 10 years. Results : 58 papers were found. Researches associated with pregnancy and acupuncture could be divided into symptoms of pregnancy, childbirth, and infertility. General acupuncture treatment, acupressure band, and finger pressure therapy was used for morning sickness. General acupuncture treatment was most commonly used for pregnancy-related back pain. Acupuncture and moxibustion treatment were used for breech presentation. Conclusion : Further research needed for more acupuncture and moxibustion treatment in pregnant women.

• Korean Journal of Radiology
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• v.22 no.4
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• pp.584-595
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• 2021

Objective: Immune checkpoint inhibitor (ICI) therapy has shown activity against melanoma brain metastases. Recently, promising results have also been reported for ICI combination therapy and ICI combined with radiotherapy. We aimed to evaluate radiologic response and adverse event rates of these therapeutic options by a systematic review and meta-analysis. Materials and Methods: A systematic literature search of Ovid-MEDLINE and EMBASE was performed up to October 12, 2019 and included studies evaluating the intracranial objective response rates (ORRs) and/or disease control rates (DCRs) of ICI with or without radiotherapy for treating melanoma brain metastases. We also evaluated safety-associated outcomes. Results: Eleven studies with 14 cohorts (3 with ICI combination therapy; 5 with ICI combined with radiotherapy; 6 with ICI monotherapy) were included. ICI combination therapy {pooled ORR, 53% (95% confidence interval [CI], 44-61%); DCR, 57% (95% CI, 49-66%)} and ICI combined with radiotherapy (pooled ORR, 42% [95% CI, 31-54%]; DCR, 85% [95% CI, 63-95%]) showed higher local efficacy compared to ICI monotherapy (pooled ORR, 15% [95% CI, 11-20%]; DCR, 26% [95% CI, 21-32%]). The grade 3 or 4 adverse event rate was significantly higher with ICI combination therapy (60%; 95% CI, 52-67%) compared to ICI monotherapy (11%; 95% CI, 8-17%) and ICI combined with radiotherapy (4%; 95% CI, 1-19%). Grade 3 or 4 central nervous system (CNS)-related adverse event rates were not different (9% in ICI combination therapy; 8% in ICI combined with radiotherapy; 5% in ICI monotherapy). Conclusion: ICI combination therapy or ICI combined with radiotherapy showed better local efficacy than ICI monotherapy for treating melanoma brain metastasis. The grade 3 or 4 adverse event rate was highest with ICI combination therapy, and the CNS-related grade 3 or 4 event rate was similar. Prospective trials will be necessary to compare the efficacy of ICI combination therapy and ICI combined with radiotherapy.

• The Journal of Churna Manual Medicine for Spine and Nerves
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• v.2 no.1
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• pp.115-125
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• 2007

Objectives : The limited number of studies to date have mainly focused on the effect of obesity on the characteristics of plantar foot pressures. This study is designed to find the correlation between plantar pressure and obese index. Methods : This study assessed the body composition of 30 obese women using bioelectrical impidence analysis and Gaitview AFA-50. The static and dynamic plantar pressure was determined from electronic footprints captured using a capacitive pressure distribution platform during standing and walking. The data were analysed by independent t-test and Pearson Correlation. Results : Positive correlations were noted between body weight, body mass index(BMI), waist circumference(WC), waist-hip ratio(WHR) and difference of fore and rear plantar pressure. And negative correlations were noted between body weight, BMI, WC, WHR and difference of left and right plantar pressure. Conclusions : The findings of this pilot study suggest that body composition influences the waight distribution in overweight and obese subjects.